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Task 56179063

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_86_1
Workunit 26681091
Created 4 Jul 2024, 21:22:23 UTC
Sent 5 Jul 2024, 7:15:16 UTC
Report deadline 8 Jul 2024, 10:08:04 UTC
Received 6 Jul 2024, 5:19:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241382
Run time 1 hours 9 min 21 sec
CPU time 44 min 5 sec
Validate state Valid
Credit 50.05
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.38 MB
Peak swap size 391.75 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_86.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_86_1_r537247808_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_15-conf_86_1_r537247808_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.893538
     * GNaL_b in INaL: 0.005773
     * Gto_b in Ito: 0.083824
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.027046
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.164299
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.625887
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032264
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22247631, states[0] = -94.676766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42375873, states[0] = -94.843490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64447182, states[0] = -94.873192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88979913, states[0] = -94.879619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113828668, states[0] = -94.786625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140448343, states[0] = -94.867620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166109260, states[0] = -14.240625, states[40]= 0.001921
Saving checkpoint... 
Iteration: 193575637, states[0] = 8.245530, states[40]= 0.004702
Saving checkpoint... 
Iteration: 219881325, states[0] = -94.833120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243283344, states[0] = -94.715126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264666889, states[0] = -65.593850, states[40]= 0.000009
Saving checkpoint... 
Iteration: 291550989, states[0] = 18.457208, states[40]= 0.002963
Saving checkpoint... 
Iteration: 320547867, states[0] = 19.593511, states[40]= 0.002721
Saving checkpoint... 
Iteration: 344988874, states[0] = -94.877764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373369664, states[0] = -94.823912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392809465, states[0] = -94.758690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418093905, states[0] = -2.002747, states[40]= 0.004456
Saving checkpoint... 
Iteration: 442334691, states[0] = -94.790857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468386453, states[0] = -94.835552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492584938, states[0] = 3.470688, states[40]= 0.004902
Saving checkpoint... 
Iteration: 519863055, states[0] = -94.818027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547449332, states[0] = -94.865734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572318397, states[0] = -94.770461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601525170, states[0] = 26.794011, states[40]= 0.001745
Saving checkpoint... 
Iteration: 626077916, states[0] = 7.141788, states[40]= 0.004791
Saving checkpoint... 
Iteration: 656691136, states[0] = -93.728799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682934796, states[0] = -94.859786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708584575, states[0] = 3.671842, states[40]= 0.004903
Saving checkpoint... 
Iteration: 736635097, states[0] = -35.832329, states[40]= 0.000764
Saving checkpoint... 
Iteration: 756582548, states[0] = 4.769221, states[40]= 0.004896
Saving checkpoint... 
Iteration: 784576492, states[0] = 7.838146, states[40]= 0.004738
Saving checkpoint... 
Iteration: 808537896, states[0] = 23.062491, states[40]= 0.002055
Saving checkpoint... 
Iteration: 835852328, states[0] = -94.807365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862235785, states[0] = -94.591742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889647411, states[0] = -46.548030, states[40]= 0.000189
Saving checkpoint... 
Iteration: 914179059, states[0] = -82.539968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937852205, states[0] = -94.806858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966087672, states[0] = 1.913801, states[40]= 0.004855
Saving checkpoint... 
Iteration: 992224780, states[0] = -94.553691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018542161, states[0] = 21.612160, states[40]= 0.002317
Saving checkpoint... 
Iteration: 1048198436, states[0] = -94.373148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066604710, states[0] = -10.303423, states[40]= 0.002661
Saving checkpoint... 
Iteration: 1090508070, states[0] = 28.582151, states[40]= 0.092526
Saving checkpoint... 
Iteration: 1117162146, states[0] = -60.542226, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1142677942, states[0] = -80.717744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169791614, states[0] = -94.726885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197768595, states[0] = -94.680305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223912500, states[0] = -94.847663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249898941, states[0] = -94.840246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277380386, states[0] = -94.828346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304249182, states[0] = -94.630531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332372955, states[0] = -94.822750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355580308, states[0] = 5.939518, states[40]= 0.004859
Saving checkpoint... 
Iteration: 1382423301, states[0] = -94.852208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407158689, states[0] = -57.111951, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1434832390, states[0] = -94.784436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462805362, states[0] = -94.748431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487777242, states[0] = -94.698028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514637650, states[0] = -64.642993, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1538799783, states[0] = -94.575360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562708494, states[0] = -94.668491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590724848, states[0] = -94.061349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618838693, states[0] = -94.475118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642616232, states[0] = -5.432671, states[40]= 0.003534
Saving checkpoint... 
Iteration: 1666799417, states[0] = -94.440150, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.307948
 - CaMKt in component CaMK (millimolar): 0.001140
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.346868
 - nass in component intracellular_ions (millimolar): 6.346954
 - ki in component intracellular_ions (millimolar): 145.550166
 - kss in component intracellular_ions (millimolar): 145.550155
 - cansr in component intracellular_ions (millimolar): 1.569104
 - cajsr in component intracellular_ions (millimolar): 1.569122
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003842
 - hf in component INa (dimensionless): 0.869306
 - hs in component INa (dimensionless): 0.869306
 - j in component INa (dimensionless): 0.869307
 - hsp in component INa (dimensionless): 0.706016
 - jp in component INa (dimensionless): 0.869308
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.713231
 - hLp in component INaL (dimensionless): 0.520687
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997655
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999216
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998764
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003018
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001899
 - xs1 in component IKs (dimensionless): 0.024293
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997489
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:01:07 (8691): called boinc_finish(0)

</stderr_txt>
]]>