𝕏

Task 56172258

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_879_1
Workunit 26677692
Created 4 Jul 2024, 21:19:20 UTC
Sent 5 Jul 2024, 6:39:55 UTC
Report deadline 8 Jul 2024, 16:15:55 UTC
Received 5 Jul 2024, 9:12:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241028
Run time 2 hours 30 min 27 sec
CPU time 2 hours 30 min 24 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 4.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 1.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_879.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_879_1_r1931820140_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_879_1_r1931820140_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.097793
     * GNaL_b in INaL: 0.005864
     * Gto_b in Ito: 0.084739
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031749
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163497
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.668144
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032160
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14703656, states[0] = -94.918680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29421902, states[0] = -95.059674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44253969, states[0] = -94.941044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58942236, states[0] = -95.035598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73702278, states[0] = -94.839717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88436884, states[0] = -95.023571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103165111, states[0] = -93.166646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117912780, states[0] = -95.013386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132800426, states[0] = -94.959248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147628342, states[0] = -46.549435, states[40]= 0.000048
Saving checkpoint... 
Iteration: 162453842, states[0] = -95.020026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177131120, states[0] = -49.436596, states[40]= 0.000031
Saving checkpoint... 
Iteration: 191876569, states[0] = -94.999117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206566389, states[0] = 4.865899, states[40]= 0.004701
Saving checkpoint... 
Iteration: 221194017, states[0] = -94.810515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235823870, states[0] = -94.973431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250459409, states[0] = -95.020150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265030095, states[0] = 18.723605, states[40]= 0.006036
Saving checkpoint... 
Iteration: 279650133, states[0] = -72.052708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294288310, states[0] = -94.947074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308882989, states[0] = -95.000999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323480076, states[0] = -95.023259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338121017, states[0] = -39.017973, states[40]= 0.000150
Saving checkpoint... 
Iteration: 352716450, states[0] = -94.854269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367291380, states[0] = -94.949662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381908040, states[0] = -95.008733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396448831, states[0] = -95.018090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411019855, states[0] = 21.287533, states[40]= 0.009769
Saving checkpoint... 
Iteration: 425628993, states[0] = -47.138696, states[40]= 0.000044
Saving checkpoint... 
Iteration: 440252355, states[0] = -94.908855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454881406, states[0] = -95.000337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469481884, states[0] = -95.023409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484073932, states[0] = 1.124188, states[40]= 0.004380
Saving checkpoint... 
Iteration: 498713322, states[0] = -94.848485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513303764, states[0] = -94.959467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527911202, states[0] = -95.009497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542526338, states[0] = 19.785042, states[40]= 0.006711
Saving checkpoint... 
Iteration: 557095851, states[0] = -15.175268, states[40]= 0.001440
Saving checkpoint... 
Iteration: 571716212, states[0] = -94.853696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586284007, states[0] = -94.943008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600870594, states[0] = -94.996211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615436618, states[0] = -95.015506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630040451, states[0] = 15.285972, states[40]= 0.005211
Saving checkpoint... 
Iteration: 644623539, states[0] = -41.524438, states[40]= 0.000104
Saving checkpoint... 
Iteration: 659226461, states[0] = -94.871245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673863236, states[0] = -94.993175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688444887, states[0] = -95.017143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703035667, states[0] = 16.950536, states[40]= 0.005478
Saving checkpoint... 
Iteration: 717707444, states[0] = -94.837260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732196158, states[0] = -94.814571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746885677, states[0] = -95.001631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761647385, states[0] = -68.189132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776433597, states[0] = -95.014754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791313108, states[0] = -94.965987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806116752, states[0] = -34.878304, states[40]= 0.000266
Saving checkpoint... 
Iteration: 820961532, states[0] = -95.020077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835745349, states[0] = -94.899399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850536062, states[0] = 16.817415, states[40]= 0.005451
Saving checkpoint... 
Iteration: 865398490, states[0] = -95.005663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880308942, states[0] = -94.963020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895175087, states[0] = -94.687430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910093909, states[0] = -13.383638, states[40]= 0.001705
Saving checkpoint... 
Iteration: 924946910, states[0] = -95.017383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939745429, states[0] = -94.899440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954368480, states[0] = -94.995146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969106934, states[0] = -25.579521, states[40]= 0.000683
Saving checkpoint... 
Iteration: 983906451, states[0] = -95.007901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998675512, states[0] = -94.698595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013514788, states[0] = 22.166066, states[40]= 0.019126
Saving checkpoint... 
Iteration: 1028257895, states[0] = -94.915296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042944981, states[0] = -95.016933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057729627, states[0] = -94.876096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072416452, states[0] = -95.010519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087334597, states[0] = -94.979046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102185356, states[0] = -94.788476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116725268, states[0] = -94.868983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131239399, states[0] = -94.890865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145906194, states[0] = -95.007725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160594785, states[0] = -14.187869, states[40]= 0.001580
Saving checkpoint... 
Iteration: 1175300328, states[0] = -94.956415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190097241, states[0] = -16.471770, states[40]= 0.001280
Saving checkpoint... 
Iteration: 1204932587, states[0] = -95.014257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219844560, states[0] = -94.984222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234700124, states[0] = -94.822428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249455446, states[0] = -95.018751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264231061, states[0] = -94.878226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278986798, states[0] = -95.023552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293764755, states[0] = -94.923054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308556530, states[0] = 9.131615, states[40]= 0.004884
Saving checkpoint... 
Iteration: 1323215319, states[0] = -94.851596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337915531, states[0] = -95.010112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352640375, states[0] = -59.591009, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1367385870, states[0] = -95.001297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382130182, states[0] = -48.395469, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1396880481, states[0] = -94.999400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411616646, states[0] = -34.776274, states[40]= 0.000269
Saving checkpoint... 
Iteration: 1426224308, states[0] = -94.867184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440842178, states[0] = -94.982867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455414752, states[0] = -95.009835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470013725, states[0] = 22.336266, states[40]= 0.023316
Saving checkpoint... 
Iteration: 1484634846, states[0] = -53.421254, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1499275244, states[0] = -94.934017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513925164, states[0] = -64.857867, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1528625231, states[0] = -66.328193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1543285173, states[0] = -20.483613, states[40]= 0.001006
Saving checkpoint... 
Iteration: 1557844016, states[0] = -95.243849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572307369, states[0] = 25.671064, states[40]= 0.091878
Saving checkpoint... 
Iteration: 1586824850, states[0] = -67.905205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1601479717, states[0] = -15.366934, states[40]= 0.001595
Saving checkpoint... 
Iteration: 1616115934, states[0] = 22.052038, states[40]= 0.017396
Saving checkpoint... 
Iteration: 1630735241, states[0] = -95.243823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645442777, states[0] = -95.253473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660049565, states[0] = -94.925049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674600776, states[0] = 44.003312, states[40]= 0.009245
Saving checkpoint... 
Iteration: 1689185242, states[0] = -95.159338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703792483, states[0] = -29.382827, states[40]= 0.000490
Saving checkpoint... 
Iteration: 1718432077, states[0] = 16.310333, states[40]= 0.006760
Saving checkpoint... 
Iteration: 1733121594, states[0] = 20.341603, states[40]= 0.009769
Saving checkpoint... 
Iteration: 1747799536, states[0] = -95.303811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762573784, states[0] = -9.312203, states[40]= 0.002800
Saving checkpoint... 
Iteration: 1777420679, states[0] = -95.224582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792258180, states[0] = 2.862251, states[40]= 0.005160
Saving checkpoint... 
Iteration: 1807010001, states[0] = 22.829716, states[40]= 0.052516
Saving checkpoint... 
Iteration: 1821678230, states[0] = -94.797428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836364311, states[0] = -95.016837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850999621, states[0] = -95.040284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865680762, states[0] = -94.780516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880293848, states[0] = -94.957282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894969755, states[0] = -95.024876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909720617, states[0] = -94.863339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924380594, states[0] = -95.000818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939042660, states[0] = 14.467500, states[40]= 0.005129
Saving checkpoint... 
Iteration: 1953728633, states[0] = -94.874635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968375805, states[0] = -94.997753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983083441, states[0] = -4.754308, states[40]= 0.003438
Saving checkpoint... 
Iteration: 1997766273, states[0] = -94.924429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012365119, states[0] = -94.993173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027034720, states[0] = 17.265316, states[40]= 0.005550
Saving checkpoint... 
Iteration: 2041701719, states[0] = -94.825126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056344711, states[0] = -94.983737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071054638, states[0] = 9.895973, states[40]= 0.004907
Saving checkpoint... 
Iteration: 2085779546, states[0] = -94.937814, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.900491
 - CaMKt in component CaMK (millimolar): 0.007004
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573263
 - nass in component intracellular_ions (millimolar): 6.573323
 - ki in component intracellular_ions (millimolar): 145.403970
 - kss in component intracellular_ions (millimolar): 145.403951
 - cansr in component intracellular_ions (millimolar): 1.313209
 - cajsr in component intracellular_ions (millimolar): 1.275146
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879977
 - hs in component INa (dimensionless): 0.879973
 - j in component INa (dimensionless): 0.879943
 - hsp in component INa (dimensionless): 0.725786
 - jp in component INa (dimensionless): 0.879924
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709730
 - hLp in component INaL (dimensionless): 0.451509
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620603
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695350
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934942
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001607
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331378
 - xs1 in component IKs (dimensionless): 0.242371
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:12:25 (31288): called boinc_finish(0)

</stderr_txt>
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