𝕏

Task 56172248

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479_1
Workunit 26677687
Created 4 Jul 2024, 21:19:20 UTC
Sent 5 Jul 2024, 6:40:07 UTC
Report deadline 8 Jul 2024, 16:16:07 UTC
Received 7 Jul 2024, 0:08:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 43 min 43 sec
CPU time 1 hours 59 min 1 sec
Validate state Valid
Credit 62.73
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.20 MB
Peak swap size 5.39 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479_1_r277356745_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479_1_r277356745_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.807458
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.084978
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031889
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.164008
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.233922
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032737
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479_1_r277356745_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_479_1_r277356745_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.807458
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.084978
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031889
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.164008
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.233922
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032737
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11395538, states[0] = -95.099543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24951026, states[0] = -95.077488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41117501, states[0] = -38.208551, states[40]= 0.000167
Saving checkpoint... 
Iteration: 57639489, states[0] = -60.995850, states[40]= 0.000004
Saving checkpoint... 
Iteration: 74998003, states[0] = -95.042539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92120348, states[0] = -39.499099, states[40]= 0.000139
Saving checkpoint... 
Iteration: 107215271, states[0] = -94.863655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122233961, states[0] = -94.893031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135741637, states[0] = -94.903281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145975823, states[0] = -95.029830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160369933, states[0] = -95.003039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175926338, states[0] = -95.019851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191307330, states[0] = -94.968836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204823112, states[0] = -94.979211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216254380, states[0] = -94.918274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226933509, states[0] = -95.020980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243608487, states[0] = -27.660524, states[40]= 0.000580
Saving checkpoint... 
Iteration: 261446574, states[0] = -95.023535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278990094, states[0] = -95.030346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292847487, states[0] = -94.992270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307835427, states[0] = -94.986047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321173404, states[0] = -94.667816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335416577, states[0] = -95.016824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349727392, states[0] = -94.879801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365388801, states[0] = -95.008780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379172719, states[0] = -94.640747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390281061, states[0] = -94.946729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401581721, states[0] = -3.897066, states[40]= 0.003611
Saving checkpoint... 
Iteration: 413260609, states[0] = -94.925399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427937206, states[0] = -95.021508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440981388, states[0] = -95.029059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455452802, states[0] = -95.024521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470464058, states[0] = -95.026441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482482337, states[0] = -95.029163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495225798, states[0] = -94.877111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506358182, states[0] = -94.997046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520969569, states[0] = -95.027281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533325869, states[0] = -94.980425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546282813, states[0] = -94.948254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561334561, states[0] = -94.985396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574670650, states[0] = -94.515684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589755587, states[0] = -94.919329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601091941, states[0] = -12.105578, states[40]= 0.001927
Saving checkpoint... 
Iteration: 615453950, states[0] = -95.024623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630704038, states[0] = -94.837719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646088183, states[0] = -8.828071, states[40]= 0.002578
Saving checkpoint... 
Iteration: 661164136, states[0] = -92.919952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676192195, states[0] = -94.813282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689279589, states[0] = -94.945143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703777854, states[0] = -94.943469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719059178, states[0] = 7.852189, states[40]= 0.004843
Saving checkpoint... 
Iteration: 732689945, states[0] = -94.808219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745151492, states[0] = -75.388618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759297956, states[0] = -94.961036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772730191, states[0] = -94.883976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788353093, states[0] = -94.994578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803202019, states[0] = -94.833601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814316293, states[0] = -94.974231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827175957, states[0] = -94.731546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841856724, states[0] = -94.996184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855188167, states[0] = -94.803945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870573699, states[0] = 0.990517, states[40]= 0.004368
Saving checkpoint... 
Iteration: 883265852, states[0] = -94.930988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897015116, states[0] = 22.017388, states[40]= 0.018014
Saving checkpoint... 
Iteration: 911583421, states[0] = -5.099207, states[40]= 0.003372
Saving checkpoint... 
Iteration: 926215074, states[0] = -94.858367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939321227, states[0] = -94.977318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953073920, states[0] = 0.870186, states[40]= 0.004354
Saving checkpoint... 
Iteration: 966156121, states[0] = -83.292124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975283197, states[0] = -94.948326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989254013, states[0] = -94.917138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002980806, states[0] = -95.028614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016434762, states[0] = -95.020609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030273542, states[0] = -94.938988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045166357, states[0] = -93.807925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059053918, states[0] = 10.014208, states[40]= 0.004912
Saving checkpoint... 
Iteration: 1071123034, states[0] = -41.748330, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1083509493, states[0] = 23.223479, states[40]= 0.059329
Saving checkpoint... 
Iteration: 1097621088, states[0] = -39.797756, states[40]= 0.000134
Saving checkpoint... 
Iteration: 1112804739, states[0] = -94.965984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128310504, states[0] = -94.970108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142424654, states[0] = -95.018262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157563214, states[0] = 6.104464, states[40]= 0.004771
Saving checkpoint... 
Iteration: 1169790855, states[0] = -94.954955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183788768, states[0] = -94.953156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195531481, states[0] = 18.180009, states[40]= 0.005852
Saving checkpoint... 
Iteration: 1208238231, states[0] = -94.895832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222781531, states[0] = -94.946624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237062048, states[0] = 6.618855, states[40]= 0.004795
Saving checkpoint... 
Iteration: 1252002168, states[0] = 43.129562, states[40]= 0.100835
Saving checkpoint... 
Iteration: 1266536949, states[0] = 16.382063, states[40]= 0.005387
Saving checkpoint... 
Iteration: 1281225899, states[0] = -94.876762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295064646, states[0] = 5.460949, states[40]= 0.004738
Saving checkpoint... 
Iteration: 1307138570, states[0] = -58.413598, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1320833782, states[0] = -94.984471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335690335, states[0] = -94.808712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350102531, states[0] = -22.023081, states[40]= 0.000848
Saving checkpoint... 
Iteration: 1363919836, states[0] = -95.016962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378957682, states[0] = -95.024783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393235351, states[0] = -94.891472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406117893, states[0] = -36.656795, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1419869706, states[0] = -95.001232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433346310, states[0] = -94.990935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447837798, states[0] = -94.986571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461669655, states[0] = -94.420841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477878861, states[0] = -95.004637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491209780, states[0] = -94.848226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503562727, states[0] = -95.223798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516648582, states[0] = -94.669845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530354314, states[0] = 5.546130, states[40]= 0.005384
Saving checkpoint... 
Iteration: 1544796556, states[0] = -33.439889, states[40]= 0.000314
Saving checkpoint... 
Iteration: 1559894217, states[0] = -95.173011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572113103, states[0] = -53.165147, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1588036379, states[0] = -88.652618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602564171, states[0] = -95.278820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616322021, states[0] = -95.230295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630761940, states[0] = -95.278373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643224673, states[0] = -68.947815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1658150888, states[0] = 6.914027, states[40]= 0.005526
Saving checkpoint... 
Iteration: 1670108666, states[0] = 24.495569, states[40]= 0.070587
Saving checkpoint... 
Iteration: 1683345702, states[0] = 9.674768, states[40]= 0.005751
Saving checkpoint... 
Iteration: 1697450404, states[0] = 7.173704, states[40]= 0.005547
Saving checkpoint... 
Iteration: 1710716814, states[0] = -58.297002, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1726367566, states[0] = -95.122567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738399337, states[0] = -95.193987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750485327, states[0] = -95.298894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765297166, states[0] = -35.097679, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1778813091, states[0] = -53.648645, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1791637483, states[0] = 13.735654, states[40]= 0.006224
Saving checkpoint... 
Iteration: 1804084777, states[0] = -9.098394, states[40]= 0.002617
Saving checkpoint... 
Iteration: 1818088076, states[0] = -10.812245, states[40]= 0.002205
Saving checkpoint... 
Iteration: 1833142119, states[0] = -64.859586, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1845539970, states[0] = 15.054530, states[40]= 0.005227
Saving checkpoint... 
Iteration: 1859945403, states[0] = -95.034093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874702455, states[0] = -94.841593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887866395, states[0] = -95.004781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903651881, states[0] = -76.417558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917818544, states[0] = -94.977093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931445699, states[0] = -95.023625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945930650, states[0] = -95.019997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959332925, states[0] = -94.984162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975150235, states[0] = -73.457228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1989272637, states[0] = -94.937653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001763869, states[0] = -94.928194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015594575, states[0] = -14.528136, states[40]= 0.001532
Saving checkpoint... 
Iteration: 2029947933, states[0] = -95.022621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044776947, states[0] = -94.941707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059108241, states[0] = -27.423725, states[40]= 0.000592
Saving checkpoint... 
Iteration: 2072561087, states[0] = 7.036532, states[40]= 0.004812
Saving checkpoint... 
Iteration: 2087354767, states[0] = -94.994454, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.906165
 - CaMKt in component CaMK (millimolar): 0.007006
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583204
 - nass in component intracellular_ions (millimolar): 6.583264
 - ki in component intracellular_ions (millimolar): 145.393794
 - kss in component intracellular_ions (millimolar): 145.393775
 - cansr in component intracellular_ions (millimolar): 1.314004
 - cajsr in component intracellular_ions (millimolar): 1.276011
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003617
 - hf in component INa (dimensionless): 0.880076
 - hs in component INa (dimensionless): 0.880071
 - j in component INa (dimensionless): 0.880042
 - hsp in component INa (dimensionless): 0.725971
 - jp in component INa (dimensionless): 0.880023
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710074
 - hLp in component INaL (dimensionless): 0.452257
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621460
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696413
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935593
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329664
 - xs1 in component IKs (dimensionless): 0.241019
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:07:33 (1856): called boinc_finish(0)

</stderr_txt>
]]>


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