𝕏

Task 56170285

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_477_1
Workunit 26676707
Created 4 Jul 2024, 21:18:27 UTC
Sent 5 Jul 2024, 6:31:51 UTC
Report deadline 8 Jul 2024, 6:32:01 UTC
Received 5 Jul 2024, 22:55:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235464
Run time 59 min 54 sec
CPU time 31 min 59 sec
Validate state Valid
Credit 50.59
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.84 MB
Peak swap size 391.82 GB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_477.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_477_1_r591167945_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_477_1_r591167945_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.344299
     * GNaL_b in INaL: 0.005791
     * Gto_b in Ito: 0.084833
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031913
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163896
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.504855
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031907
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 16307973, states[0] = -84.484526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37955129, states[0] = 30.181301, states[40]= 0.359121
Saving checkpoint... 
Iteration: 55813036, states[0] = 23.951720, states[40]= 0.000007
Saving checkpoint... 
Iteration: 77946877, states[0] = 25.620562, states[40]= 0.000014
Saving checkpoint... 
Iteration: 95627580, states[0] = -84.247460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115020762, states[0] = 30.741230, states[40]= 0.001361
Saving checkpoint... 
Iteration: 128351807, states[0] = -54.739488, states[40]= 0.000018
Saving checkpoint... 
Iteration: 142943485, states[0] = 14.450181, states[40]= 0.000032
Saving checkpoint... 
Iteration: 157107081, states[0] = -61.120127, states[40]= 0.000008
Saving checkpoint... 
Iteration: 170803032, states[0] = 28.309204, states[40]= 0.000104
Saving checkpoint... 
Iteration: 190208918, states[0] = -84.182227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213344394, states[0] = 31.045696, states[40]= 0.002217
Saving checkpoint... 
Iteration: 236053554, states[0] = 31.507817, states[40]= 0.007317
Saving checkpoint... 
Iteration: 256822779, states[0] = -6.905698, states[40]= 0.000272
Saving checkpoint... 
Iteration: 282391129, states[0] = 8.351534, states[40]= 0.000086
Saving checkpoint... 
Iteration: 301078425, states[0] = 8.481695, states[40]= 0.000085
Saving checkpoint... 
Iteration: 319180791, states[0] = 14.556442, states[40]= 0.000031
Saving checkpoint... 
Iteration: 336669155, states[0] = 29.816067, states[40]= 0.212286
Saving checkpoint... 
Iteration: 354907403, states[0] = -61.528511, states[40]= 0.000007
Saving checkpoint... 
Iteration: 371965977, states[0] = -84.601310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385837267, states[0] = 31.330482, states[40]= 0.028485
Saving checkpoint... 
Iteration: 398829720, states[0] = 7.652235, states[40]= 0.000095
Saving checkpoint... 
Iteration: 413450795, states[0] = 29.161918, states[40]= 0.000228
Saving checkpoint... 
Iteration: 432395595, states[0] = -84.789647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450500551, states[0] = -84.770454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471563385, states[0] = 10.072892, states[40]= 0.000067
Saving checkpoint... 
Iteration: 494027628, states[0] = -27.298243, states[40]= 0.000174
Saving checkpoint... 
Iteration: 514760999, states[0] = -66.153400, states[40]= 0.000004
Saving checkpoint... 
Iteration: 537047383, states[0] = -84.790829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559682087, states[0] = -84.473382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579633776, states[0] = 25.858251, states[40]= 0.000016
Saving checkpoint... 
Iteration: 604386869, states[0] = 10.999605, states[40]= 0.000058
Saving checkpoint... 
Iteration: 620757429, states[0] = 20.433866, states[40]= 0.000009
Saving checkpoint... 
Iteration: 646782073, states[0] = -84.381321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672065225, states[0] = -84.235165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696963394, states[0] = 10.070598, states[40]= 0.000067
Saving checkpoint... 
Iteration: 720572750, states[0] = -21.582969, states[40]= 0.000173
Saving checkpoint... 
Iteration: 750048031, states[0] = -84.675146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777135980, states[0] = 29.959262, states[40]= 0.000518
Saving checkpoint... 
Iteration: 795905872, states[0] = -31.006675, states[40]= 0.000162
Saving checkpoint... 
Iteration: 818850325, states[0] = 17.590454, states[40]= 0.000017
Saving checkpoint... 
Iteration: 835356689, states[0] = -84.134486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854696950, states[0] = -84.668031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879592843, states[0] = -58.953778, states[40]= 0.000010
Saving checkpoint... 
Iteration: 899048301, states[0] = 24.930137, states[40]= 0.000010
Saving checkpoint... 
Iteration: 920800967, states[0] = -84.572887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 943296431, states[0] = 30.451602, states[40]= 0.094314
Saving checkpoint... 
Iteration: 967638239, states[0] = -84.417898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988672352, states[0] = -84.665730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009124070, states[0] = -84.781241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033395571, states[0] = -47.572157, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1054978459, states[0] = -72.802316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078532425, states[0] = -46.838130, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1110013775, states[0] = -84.718422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134848806, states[0] = -7.987536, states[40]= 0.000269
Saving checkpoint... 
Iteration: 1155151463, states[0] = -84.717707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180561165, states[0] = -7.831231, states[40]= 0.000269
Saving checkpoint... 
Iteration: 1202018728, states[0] = -84.730426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213941378, states[0] = -42.832531, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1225049022, states[0] = 31.195349, states[40]= 0.037207
Saving checkpoint... 
Iteration: 1237559026, states[0] = -83.810737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259080605, states[0] = -44.774105, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1285123495, states[0] = -84.772093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305894255, states[0] = 6.329128, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1330329468, states[0] = 7.829736, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1352521394, states[0] = -48.490632, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1372720836, states[0] = -84.369846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383813085, states[0] = 1.835475, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1392312130, states[0] = -84.612266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399865893, states[0] = 28.177700, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1411078456, states[0] = 28.152544, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1426016524, states[0] = 31.485035, states[40]= 0.006178
Saving checkpoint... 
Iteration: 1446332363, states[0] = -84.449462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466029340, states[0] = 7.914319, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1484048812, states[0] = -84.700091, states[40]= 0.000001
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.645143
 - CaMKt in component CaMK (millimolar): 0.056411
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.907278
 - nass in component intracellular_ions (millimolar): 6.907455
 - ki in component intracellular_ions (millimolar): 144.674138
 - kss in component intracellular_ions (millimolar): 144.674108
 - cansr in component intracellular_ions (millimolar): 2.236671
 - cajsr in component intracellular_ions (millimolar): 1.851787
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010161
 - hf in component INa (dimensionless): 0.576186
 - hs in component INa (dimensionless): 0.575946
 - j in component INa (dimensionless): 0.574591
 - hsp in component INa (dimensionless): 0.328535
 - jp in component INa (dimensionless): 0.573081
 - mL in component INaL (dimensionless): 0.000348
 - hL in component INaL (dimensionless): 0.322188
 - hLp in component INaL (dimensionless): 0.137274
 - a in component Ito (dimensionless): 0.001245
 - iF in component Ito (dimensionless): 0.999214
 - iS in component Ito (dimensionless): 0.305706
 - ap in component Ito (dimensionless): 0.000634
 - iFp in component Ito (dimensionless): 0.999214
 - iSp in component Ito (dimensionless): 0.336507
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.813115
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990413
 - jca in component ICaL (dimensionless): 0.994324
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007787
 - xrf in component IKr (dimensionless): 0.001952
 - xrs in component IKr (dimensionless): 0.726398
 - xs1 in component IKs (dimensionless): 0.425765
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996767
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:01:49 (3863): called boinc_finish(0)

</stderr_txt>
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