𝕏

Task 56170283

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377_1
Workunit 26676706
Created 4 Jul 2024, 21:18:27 UTC
Sent 5 Jul 2024, 6:31:51 UTC
Report deadline 8 Jul 2024, 6:32:01 UTC
Received 5 Jul 2024, 20:40:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235464
Run time 47 min 8 sec
CPU time 27 min 54 sec
Validate state Valid
Credit 48.24
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.09 MB
Peak swap size 391.94 GB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377_1_r783049650_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377_1_r783049650_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.409655
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.084174
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.163423
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.253573
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032212
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 20164722, states[0] = 23.156863, states[40]= 0.000013
Saving checkpoint... 
Iteration: 42889778, states[0] = 16.702581, states[40]= 0.000023
Saving checkpoint... 
Iteration: 64050183, states[0] = -84.576805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88707392, states[0] = -83.660972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112046034, states[0] = -84.486513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132066968, states[0] = -29.258752, states[40]= 0.000168
Saving checkpoint... 
Iteration: 157940631, states[0] = -27.745982, states[40]= 0.000171
Saving checkpoint... 
Iteration: 179079364, states[0] = -84.707708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206023025, states[0] = -84.191505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227581911, states[0] = -84.146010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252327612, states[0] = -84.349475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274163076, states[0] = -84.216961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298069442, states[0] = -84.548870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319697104, states[0] = -84.790186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344583411, states[0] = -83.767489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367894739, states[0] = -84.278215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394193355, states[0] = 27.160017, states[40]= 0.000039
Saving checkpoint... 
Iteration: 413002223, states[0] = -82.624060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438426831, states[0] = -84.767836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462896088, states[0] = 30.674627, states[40]= 0.001209
Saving checkpoint... 
Iteration: 488151342, states[0] = -84.729969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508776797, states[0] = -84.335244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533673142, states[0] = 3.661596, states[40]= 0.000152
Saving checkpoint... 
Iteration: 559137929, states[0] = -84.632902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579764494, states[0] = -84.044991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599784687, states[0] = 12.323659, states[40]= 0.000045
Saving checkpoint... 
Iteration: 617970282, states[0] = -61.727275, states[40]= 0.000007
Saving checkpoint... 
Iteration: 641170115, states[0] = 20.352518, states[40]= 0.000009
Saving checkpoint... 
Iteration: 662472428, states[0] = 4.172313, states[40]= 0.000143
Saving checkpoint... 
Iteration: 685246350, states[0] = -63.069730, states[40]= 0.000006
Saving checkpoint... 
Iteration: 707463166, states[0] = -84.500279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735384696, states[0] = -84.665734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746255035, states[0] = -84.354594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750258853, states[0] = -84.155765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753901406, states[0] = 1.231921, states[40]= 0.000192
Saving checkpoint... 
Iteration: 757776702, states[0] = -84.505095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760277327, states[0] = -55.141643, states[40]= 0.000017
Saving checkpoint... 
Iteration: 762043603, states[0] = -84.118277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764388223, states[0] = -84.498972, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766842842, states[0] = -2.023562, states[40]= 0.000239
Saving checkpoint... 
Iteration: 769348879, states[0] = -84.781417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 771783314, states[0] = -62.384668, states[40]= 0.000006


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377_1_r783049650_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_377_1_r783049650_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.409655
     * GNaL_b in INaL: 0.005757
     * Gto_b in Ito: 0.084174
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.163423
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.253573
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032212
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 771783314
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -62.384668 (After loading)
 - states[40]: 0.000006 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 807384424, states[0] = -5.917830, states[40]= 0.000265
Saving checkpoint... 
Iteration: 834777999, states[0] = -84.060494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851210073, states[0] = -84.476827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865661061, states[0] = -84.777947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889640433, states[0] = -41.619835, states[40]= 0.000077
Saving checkpoint... 
Iteration: 916857551, states[0] = 30.933913, states[40]= 0.001749
Saving checkpoint... 
Iteration: 939570262, states[0] = 30.885125, states[40]= 0.001623
Saving checkpoint... 
Iteration: 962017263, states[0] = 21.807581, states[40]= 0.000007
Saving checkpoint... 
Iteration: 985070209, states[0] = -18.416466, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1009604884, states[0] = -84.345669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038085596, states[0] = -84.474705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058618531, states[0] = 21.168129, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1081298909, states[0] = 31.204659, states[40]= 0.038733
Saving checkpoint... 
Iteration: 1100074881, states[0] = -23.955747, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1118888796, states[0] = -84.561792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1139063880, states[0] = -84.746647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157311311, states[0] = -51.059968, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1179174062, states[0] = -66.555388, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1200477709, states[0] = -84.042801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218951515, states[0] = -84.618579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237519200, states[0] = -45.830928, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1253704348, states[0] = -84.427258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265721073, states[0] = -78.609006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277755622, states[0] = -30.563456, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1294625622, states[0] = 31.489228, states[40]= 0.020920
Saving checkpoint... 
Iteration: 1316185710, states[0] = 31.036729, states[40]= 0.049789
Saving checkpoint... 
Iteration: 1337240185, states[0] = 0.232096, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1358787081, states[0] = 10.904072, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1378543209, states[0] = -84.717449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402188936, states[0] = 17.010427, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1421158730, states[0] = 19.783993, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1441968939, states[0] = -83.516388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461416835, states[0] = 15.409757, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1481132432, states[0] = -84.517305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1500137684, states[0] = -84.654989, states[40]= 0.000001
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.638865
 - CaMKt in component CaMK (millimolar): 0.056465
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.911999
 - nass in component intracellular_ions (millimolar): 6.912175
 - ki in component intracellular_ions (millimolar): 144.668829
 - kss in component intracellular_ions (millimolar): 144.668799
 - cansr in component intracellular_ions (millimolar): 2.235835
 - cajsr in component intracellular_ions (millimolar): 1.849924
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010167
 - hf in component INa (dimensionless): 0.575934
 - hs in component INa (dimensionless): 0.575693
 - j in component INa (dimensionless): 0.574332
 - hsp in component INa (dimensionless): 0.328305
 - jp in component INa (dimensionless): 0.572813
 - mL in component INaL (dimensionless): 0.000348
 - hL in component INaL (dimensionless): 0.321770
 - hLp in component INaL (dimensionless): 0.136996
 - a in component Ito (dimensionless): 0.001245
 - iF in component Ito (dimensionless): 0.999213
 - iS in component Ito (dimensionless): 0.305392
 - ap in component Ito (dimensionless): 0.000635
 - iFp in component Ito (dimensionless): 0.999213
 - iSp in component Ito (dimensionless): 0.336102
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.812889
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990382
 - jca in component ICaL (dimensionless): 0.994308
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007779
 - xrf in component IKr (dimensionless): 0.001971
 - xrs in component IKr (dimensionless): 0.726768
 - xs1 in component IKs (dimensionless): 0.426035
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996769
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:10:21 (1112): called boinc_finish(0)

</stderr_txt>
]]>


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