𝕏

Task 56170066

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_677_1
Workunit 26676599
Created 4 Jul 2024, 21:18:17 UTC
Sent 5 Jul 2024, 6:31:51 UTC
Report deadline 8 Jul 2024, 6:31:51 UTC
Received 6 Jul 2024, 1:00:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235464
Run time 1 hours 16 min 14 sec
CPU time 34 min 9 sec
Validate state Valid
Credit 48.61
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.03 MB
Peak swap size 391.82 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_677.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_677_1_r177441623_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_677_1_r177441623_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.191096
     * GNaL_b in INaL: 0.005746
     * Gto_b in Ito: 0.084010
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031977
     * GKs_b in IKs: 0.001928
     * GK1_b in IK1: 0.162578
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.312475
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033781
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 20457572, states[0] = -87.665567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38246745, states[0] = -48.737746, states[40]= 0.000045
Saving checkpoint... 
Iteration: 49731504, states[0] = -29.299905, states[40]= 0.000553
Saving checkpoint... 
Iteration: 59643698, states[0] = -87.768253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70267724, states[0] = -85.006822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80336148, states[0] = 22.260858, states[40]= 0.039409
Saving checkpoint... 
Iteration: 88421055, states[0] = -68.292285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 97384622, states[0] = -17.081855, states[40]= 0.001672
Saving checkpoint... 
Iteration: 106578304, states[0] = -56.423793, states[40]= 0.000014
Saving checkpoint... 
Iteration: 120603972, states[0] = -87.401680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136532727, states[0] = 0.871434, states[40]= 0.006208
Saving checkpoint... 
Iteration: 153522741, states[0] = 7.664408, states[40]= 0.007261
Saving checkpoint... 
Iteration: 169071750, states[0] = -56.020889, states[40]= 0.000015
Saving checkpoint... 
Iteration: 179728642, states[0] = -43.621422, states[40]= 0.000097
Saving checkpoint... 
Iteration: 187246136, states[0] = -71.196383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199896224, states[0] = -47.730633, states[40]= 0.000053
Saving checkpoint... 
Iteration: 215809077, states[0] = -87.816964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233450472, states[0] = -87.741324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248765976, states[0] = -87.655038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268691013, states[0] = -4.105229, states[40]= 0.005017
Saving checkpoint... 
Iteration: 284780632, states[0] = -87.748675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294564492, states[0] = -64.097984, states[40]= 0.000004
Saving checkpoint... 
Iteration: 303169892, states[0] = 10.823528, states[40]= 0.007709
Saving checkpoint... 
Iteration: 313244223, states[0] = -85.602362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322361304, states[0] = -15.964554, states[40]= 0.001867
Saving checkpoint... 
Iteration: 332370808, states[0] = -30.837596, states[40]= 0.000477
Saving checkpoint... 
Iteration: 347220958, states[0] = -56.552104, states[40]= 0.000014
Saving checkpoint... 
Iteration: 365653154, states[0] = 16.992745, states[40]= 0.009695
Saving checkpoint... 
Iteration: 389279152, states[0] = -87.779435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407299674, states[0] = 24.593040, states[40]= 0.085360
Saving checkpoint... 
Iteration: 420538684, states[0] = -44.726939, states[40]= 0.000083
Saving checkpoint... 
Iteration: 429656693, states[0] = 11.184990, states[40]= 0.007766
Saving checkpoint... 
Iteration: 439104538, states[0] = -87.769562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449236398, states[0] = -87.273810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459212433, states[0] = -60.565132, states[40]= 0.000007
Saving checkpoint... 
Iteration: 471067343, states[0] = -87.249592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485066762, states[0] = -87.338081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505325147, states[0] = 4.374378, states[40]= 0.006806
Saving checkpoint... 
Iteration: 529027782, states[0] = -44.650108, states[40]= 0.000084
Saving checkpoint... 
Iteration: 547094898, states[0] = -87.773395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557953502, states[0] = 22.988310, states[40]= 0.054193
Saving checkpoint... 
Iteration: 567597656, states[0] = -87.788822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578218505, states[0] = -86.004188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591482130, states[0] = 5.233813, states[40]= 0.006930
Saving checkpoint... 
Iteration: 613743107, states[0] = -87.730553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631321266, states[0] = -3.942371, states[40]= 0.005062
Saving checkpoint... 
Iteration: 647605464, states[0] = 31.728149, states[40]= 0.122882
Saving checkpoint... 
Iteration: 667409024, states[0] = -87.748136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688573400, states[0] = -87.747459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708633598, states[0] = 7.874833, states[40]= 0.007290
Saving checkpoint... 
Iteration: 729493387, states[0] = -24.700428, states[40]= 0.000838
Saving checkpoint... 
Iteration: 751355007, states[0] = -68.825296, states[40]= 0.000002
Saving checkpoint... 
Iteration: 772484696, states[0] = -18.449693, states[40]= 0.001465
Saving checkpoint... 
Iteration: 792475716, states[0] = -8.713225, states[40]= 0.003660
Saving checkpoint... 
Iteration: 818757960, states[0] = 25.199998, states[40]= 0.094733
Saving checkpoint... 
Iteration: 837497280, states[0] = -45.139694, states[40]= 0.000078
Saving checkpoint... 
Iteration: 856801335, states[0] = -7.067397, states[40]= 0.004151
Saving checkpoint... 
Iteration: 869066543, states[0] = -87.785301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879362850, states[0] = -87.492620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887447159, states[0] = 9.219184, states[40]= 0.007473
Saving checkpoint... 
Iteration: 896359302, states[0] = -87.368406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907604491, states[0] = 13.926340, states[40]= 0.008326
Saving checkpoint... 
Iteration: 915825105, states[0] = -48.408744, states[40]= 0.000048
Saving checkpoint... 
Iteration: 928976891, states[0] = -29.554454, states[40]= 0.000541
Saving checkpoint... 
Iteration: 941359654, states[0] = -87.596975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956172939, states[0] = -77.586753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966473337, states[0] = -29.828122, states[40]= 0.000527
Saving checkpoint... 
Iteration: 980001517, states[0] = -73.515962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991138023, states[0] = -30.506058, states[40]= 0.000493
Saving checkpoint... 
Iteration: 1000852288, states[0] = -87.557937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015666684, states[0] = -77.078349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027703961, states[0] = -87.738714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038231926, states[0] = 36.925586, states[40]= 0.099021
Saving checkpoint... 
Iteration: 1050911819, states[0] = 19.836497, states[40]= 0.014932
Saving checkpoint... 
Iteration: 1060217789, states[0] = -87.796431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068788350, states[0] = -18.381777, states[40]= 0.001475
Saving checkpoint... 
Iteration: 1079890526, states[0] = -87.819187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091440418, states[0] = -2.303310, states[40]= 0.005497
Saving checkpoint... 
Iteration: 1109186411, states[0] = -87.698561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132604381, states[0] = -3.846757, states[40]= 0.005089
Saving checkpoint... 
Iteration: 1152283505, states[0] = -23.382718, states[40]= 0.000939
Saving checkpoint... 
Iteration: 1171046154, states[0] = -87.813843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192488737, states[0] = -85.038188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214302095, states[0] = -58.314016, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1238649188, states[0] = -83.698072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264265046, states[0] = -13.048816, states[40]= 0.002484
Saving checkpoint... 
Iteration: 1295060201, states[0] = 16.994339, states[40]= 0.009696
Saving checkpoint... 
Iteration: 1322645848, states[0] = -86.669463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351534026, states[0] = 36.406174, states[40]= 0.102321
Saving checkpoint... 
Iteration: 1379881907, states[0] = 18.526527, states[40]= 0.011461
Saving checkpoint... 
Iteration: 1411788315, states[0] = -67.739366, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1437133556, states[0] = -86.395440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462182837, states[0] = -87.810973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491456918, states[0] = -83.371334, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.698045
 - CaMKt in component CaMK (millimolar): 0.042051
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.004752
 - nass in component intracellular_ions (millimolar): 7.004900
 - ki in component intracellular_ions (millimolar): 144.916458
 - kss in component intracellular_ions (millimolar): 144.916425
 - cansr in component intracellular_ions (millimolar): 1.616041
 - cajsr in component intracellular_ions (millimolar): 1.185805
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007478
 - hf in component INa (dimensionless): 0.691853
 - hs in component INa (dimensionless): 0.691614
 - j in component INa (dimensionless): 0.681145
 - hsp in component INa (dimensionless): 0.446636
 - jp in component INa (dimensionless): 0.654762
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293272
 - hLp in component INaL (dimensionless): 0.136315
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.176053
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.213068
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804419
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966931
 - jca in component ICaL (dimensionless): 0.948216
 - ffp in component ICaL (dimensionless): 0.999866
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009425
 - xrf in component IKr (dimensionless): 0.028571
 - xrs in component IKr (dimensionless): 0.787475
 - xs1 in component IKs (dimensionless): 0.458279
 - xs2 in component IKs (dimensionless): 0.001175
 - xk1 in component IK1 (dimensionless): 0.996812
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:32:33 (10071): called boinc_finish(0)

</stderr_txt>
]]>