𝕏

Task 56170050

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777_1
Workunit 26676591
Created 4 Jul 2024, 21:18:17 UTC
Sent 5 Jul 2024, 6:31:51 UTC
Report deadline 8 Jul 2024, 6:31:51 UTC
Received 5 Jul 2024, 20:40:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235464
Run time 46 min 3 sec
CPU time 27 min 22 sec
Validate state Valid
Credit 43.76
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.05 MB
Peak swap size 391.94 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777_1_r568056076_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777_1_r568056076_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.101350
     * GNaL_b in INaL: 0.005921
     * Gto_b in Ito: 0.085377
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031730
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.164135
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.117934
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032133
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 24265651, states[0] = -86.957263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48421060, states[0] = -86.997387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73272382, states[0] = -86.888386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93023926, states[0] = 20.978186, states[40]= 0.006509
Saving checkpoint... 
Iteration: 114506808, states[0] = 24.276397, states[40]= 0.099926
Saving checkpoint... 
Iteration: 130761792, states[0] = -86.858769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156994081, states[0] = -86.968510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175816249, states[0] = -86.907339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196961159, states[0] = -86.962267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213291340, states[0] = -86.886479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237587162, states[0] = -8.244638, states[40]= 0.002646
Saving checkpoint... 
Iteration: 255487902, states[0] = -86.965901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276429557, states[0] = -86.955178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297860215, states[0] = -86.931647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318156061, states[0] = -83.176945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335098882, states[0] = -19.432209, states[40]= 0.000964
Saving checkpoint... 
Iteration: 358558854, states[0] = 8.323427, states[40]= 0.004682
Saving checkpoint... 
Iteration: 386562541, states[0] = 6.694174, states[40]= 0.004639
Saving checkpoint... 
Iteration: 411947000, states[0] = -86.958861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434477445, states[0] = -86.964173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456807625, states[0] = -86.899656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484136222, states[0] = -58.013728, states[40]= 0.000007
Saving checkpoint... 
Iteration: 508082940, states[0] = -4.837236, states[40]= 0.003347
Saving checkpoint... 
Iteration: 532894850, states[0] = -86.945104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554889032, states[0] = -86.943098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580021215, states[0] = 21.687436, states[40]= 0.007597
Saving checkpoint... 
Iteration: 607064153, states[0] = 5.956660, states[40]= 0.004611
Saving checkpoint... 
Iteration: 619598560, states[0] = -19.110340, states[40]= 0.000989
Saving checkpoint... 
Iteration: 643810513, states[0] = -86.901728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667380603, states[0] = -86.939930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694525080, states[0] = 20.778301, states[40]= 0.006231
Saving checkpoint... 
Iteration: 717456541, states[0] = -86.960482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741587808, states[0] = -8.798599, states[40]= 0.002531
Saving checkpoint... 
Iteration: 765198312, states[0] = -86.749748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786934435, states[0] = -86.955889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813688446, states[0] = -86.729214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832427953, states[0] = -86.954332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837005781, states[0] = 25.247663, states[40]= 0.125355
Saving checkpoint... 
Iteration: 840535997, states[0] = 17.348307, states[40]= 0.005013
Saving checkpoint... 
Iteration: 844689398, states[0] = -86.731235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848247651, states[0] = -86.835691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849837904, states[0] = -86.919671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851537600, states[0] = 16.772157, states[40]= 0.004943
Saving checkpoint... 
Iteration: 854136752, states[0] = -58.630292, states[40]= 0.000006
Saving checkpoint... 
Iteration: 856629298, states[0] = -50.286106, states[40]= 0.000024
Saving checkpoint... 
Iteration: 859160124, states[0] = -85.384979, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777_1_r568056076_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_777_1_r568056076_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.101350
     * GNaL_b in INaL: 0.005921
     * Gto_b in Ito: 0.085377
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031730
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.164135
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.117934
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032133
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 859160124
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -85.384979 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 897399398, states[0] = -86.946321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921562140, states[0] = 6.875323, states[40]= 0.004645
Saving checkpoint... 
Iteration: 937834097, states[0] = -86.917374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950181887, states[0] = -86.713424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981773487, states[0] = -86.867719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011002685, states[0] = 34.253466, states[40]= 0.153283
Saving checkpoint... 
Iteration: 1029373031, states[0] = -86.936675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053038164, states[0] = 16.566494, states[40]= 0.004921
Saving checkpoint... 
Iteration: 1074278553, states[0] = -86.873042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098575842, states[0] = -0.106621, states[40]= 0.004123
Saving checkpoint... 
Iteration: 1125414615, states[0] = -86.950669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148081401, states[0] = -3.713231, states[40]= 0.003561
Saving checkpoint... 
Iteration: 1168095878, states[0] = -16.441309, states[40]= 0.001247
Saving checkpoint... 
Iteration: 1191260619, states[0] = -86.852587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212201232, states[0] = -86.755319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234739108, states[0] = -86.822890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255483347, states[0] = -86.964442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275970670, states[0] = -86.962512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294650045, states[0] = -76.272533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313730543, states[0] = -86.809253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328532165, states[0] = 18.664596, states[40]= 0.005255
Saving checkpoint... 
Iteration: 1348141983, states[0] = -65.047107, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1356479563, states[0] = -86.963822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367337933, states[0] = -86.919312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380576127, states[0] = -0.276474, states[40]= 0.004101
Saving checkpoint... 
Iteration: 1402965136, states[0] = -86.961507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425020458, states[0] = 21.840682, states[40]= 0.008033
Saving checkpoint... 
Iteration: 1445625164, states[0] = -45.873443, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1466570003, states[0] = 3.110256, states[40]= 0.004447
Saving checkpoint... 
Iteration: 1489731919, states[0] = -86.811377, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.842315
 - CaMKt in component CaMK (millimolar): 0.006805
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.411603
 - nass in component intracellular_ions (millimolar): 6.411660
 - ki in component intracellular_ions (millimolar): 145.571622
 - kss in component intracellular_ions (millimolar): 145.571603
 - cansr in component intracellular_ions (millimolar): 1.295995
 - cajsr in component intracellular_ions (millimolar): 1.258113
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008150
 - hf in component INa (dimensionless): 0.661092
 - hs in component INa (dimensionless): 0.661080
 - j in component INa (dimensionless): 0.661016
 - hsp in component INa (dimensionless): 0.413205
 - jp in component INa (dimensionless): 0.660972
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466045
 - hLp in component INaL (dimensionless): 0.240587
 - a in component Ito (dimensionless): 0.001073
 - iF in component Ito (dimensionless): 0.999466
 - iS in component Ito (dimensionless): 0.577833
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999466
 - iSp in component Ito (dimensionless): 0.632200
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934826
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001535
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.406704
 - xs1 in component IKs (dimensionless): 0.243349
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997021
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:03:30 (1110): called boinc_finish(0)

</stderr_txt>
]]>