𝕏

Task 56168155

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0
Workunit 26675645
Created 4 Jul 2024, 21:17:25 UTC
Sent 5 Jul 2024, 6:22:23 UTC
Report deadline 8 Jul 2024, 6:22:23 UTC
Received 5 Jul 2024, 22:56:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 1 hours 55 min 49 sec
CPU time 1 hours 36 min 26 sec
Validate state Valid
Credit 45.22
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.88 MB
Peak swap size 4.38 GB
Peak disk usage 0.19 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0_r2091344193_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0_r2091344193_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.447953
     * GNaL_b in INaL: 0.005790
     * Gto_b in Ito: 0.083729
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031867
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162732
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.389493
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032971
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14847657, states[0] = -24.103028, states[40]= 0.000407
Saving checkpoint... 
Iteration: 29875233, states[0] = -57.148141, states[40]= 0.000019
Saving checkpoint... 
Iteration: 44919858, states[0] = -84.352695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59767648, states[0] = 31.263689, states[40]= 0.004157
Saving checkpoint... 
Iteration: 74698682, states[0] = -84.620579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89641102, states[0] = -79.338471, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0_r2091344193_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0_r2091344193_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.447953
     * GNaL_b in INaL: 0.005790
     * Gto_b in Ito: 0.083729
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031867
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162732
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.389493
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032971
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 89641102
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -79.338471 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 99899246, states[0] = -83.473383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110169902, states[0] = -84.377376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119142308, states[0] = -80.507183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128842229, states[0] = -19.662060, states[40]= 0.000167
Saving checkpoint... 
Iteration: 138914799, states[0] = -84.317325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148617371, states[0] = -49.582671, states[40]= 0.000038
Saving checkpoint... 
Iteration: 159101143, states[0] = -30.565375, states[40]= 0.000163
Saving checkpoint... 
Iteration: 168598779, states[0] = -27.741175, states[40]= 0.000169
Saving checkpoint... 
Iteration: 177578071, states[0] = -2.939471, states[40]= 0.000218
Saving checkpoint... 
Iteration: 187564457, states[0] = 7.918177, states[40]= 0.000070
Saving checkpoint... 
Iteration: 198185720, states[0] = -84.527366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208627112, states[0] = -61.498437, states[40]= 0.000009
Saving checkpoint... 
Iteration: 217862154, states[0] = -43.495991, states[40]= 0.000071
Saving checkpoint... 
Iteration: 226611293, states[0] = -42.492249, states[40]= 0.000078
Saving checkpoint... 
Iteration: 234544351, states[0] = 20.008487, states[40]= 0.000006
Saving checkpoint... 
Iteration: 242607000, states[0] = -37.484978, states[40]= 0.000117
Saving checkpoint... 
Iteration: 253479317, states[0] = -84.799062, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0_r2091344193_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_500-conf_775_0_r2091344193_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.447953
     * GNaL_b in INaL: 0.005790
     * Gto_b in Ito: 0.083729
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031867
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162732
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.389493
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032971
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 253479317
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.799062 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 266887509, states[0] = -75.567325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 280458039, states[0] = -84.685954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293272329, states[0] = 30.071091, states[40]= 0.000773
Saving checkpoint... 
Iteration: 305273324, states[0] = 29.751634, states[40]= 0.000542
Saving checkpoint... 
Iteration: 317837302, states[0] = -13.486728, states[40]= 0.000203
Saving checkpoint... 
Iteration: 331059079, states[0] = 11.439530, states[40]= 0.000039
Saving checkpoint... 
Iteration: 344374598, states[0] = -58.312126, states[40]= 0.000014
Saving checkpoint... 
Iteration: 357636835, states[0] = -74.684690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 370391910, states[0] = -80.238693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383556135, states[0] = 13.264916, states[40]= 0.000027
Saving checkpoint... 
Iteration: 396847209, states[0] = -25.847543, states[40]= 0.000168
Saving checkpoint... 
Iteration: 409936325, states[0] = -84.524784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423555444, states[0] = 13.684848, states[40]= 0.000025
Saving checkpoint... 
Iteration: 436635418, states[0] = -72.767499, states[40]= 0.000002
Saving checkpoint... 
Iteration: 449777732, states[0] = 28.095802, states[40]= 0.000113
Saving checkpoint... 
Iteration: 462997875, states[0] = -84.864397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476150035, states[0] = -83.618879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489256256, states[0] = 29.673925, states[40]= 0.255580
Saving checkpoint... 
Iteration: 502526335, states[0] = 28.658426, states[40]= 0.000185
Saving checkpoint... 
Iteration: 515790453, states[0] = 22.072520, states[40]= 0.000005
Saving checkpoint... 
Iteration: 529348353, states[0] = -27.224536, states[40]= 0.000169
Saving checkpoint... 
Iteration: 542763628, states[0] = 31.346127, states[40]= 0.017803
Saving checkpoint... 
Iteration: 555913008, states[0] = -84.277251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569214622, states[0] = -84.713935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582652024, states[0] = -83.854173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595784410, states[0] = 25.094758, states[40]= 0.000012
Saving checkpoint... 
Iteration: 608979884, states[0] = -84.788705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622201738, states[0] = -84.632933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634978218, states[0] = -84.780248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648025438, states[0] = 29.004897, states[40]= 0.000255
Saving checkpoint... 
Iteration: 660269617, states[0] = 30.807075, states[40]= 0.002045
Saving checkpoint... 
Iteration: 674029453, states[0] = 27.369996, states[40]= 0.000062
Saving checkpoint... 
Iteration: 687412924, states[0] = -84.270974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700391174, states[0] = -79.572355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713771037, states[0] = 30.453086, states[40]= 0.001228
Saving checkpoint... 
Iteration: 727558908, states[0] = 11.554165, states[40]= 0.000038
Saving checkpoint... 
Iteration: 740773695, states[0] = 29.632624, states[40]= 0.000474
Saving checkpoint... 
Iteration: 754190952, states[0] = -84.549580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767251615, states[0] = 36.812154, states[40]= 1.118836
Saving checkpoint... 
Iteration: 779480991, states[0] = -84.787402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 791993610, states[0] = -84.837438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804398449, states[0] = -83.310181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816857864, states[0] = -38.464444, states[40]= 0.000109
Saving checkpoint... 
Iteration: 829467868, states[0] = -84.722119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842171453, states[0] = -84.370054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854347772, states[0] = -26.505993, states[40]= 0.000168
Saving checkpoint... 
Iteration: 867483536, states[0] = -84.795158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879822016, states[0] = 2.393064, states[40]= 0.000145
Saving checkpoint... 
Iteration: 892981633, states[0] = -84.786082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906505281, states[0] = 29.916365, states[40]= 0.360483
Saving checkpoint... 
Iteration: 920788935, states[0] = 22.858244, states[40]= 0.000005
Saving checkpoint... 
Iteration: 935288989, states[0] = 22.830940, states[40]= 0.000005
Saving checkpoint... 
Iteration: 949910948, states[0] = -84.227319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964449979, states[0] = -84.608379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978782714, states[0] = 25.903181, states[40]= 0.000020
Saving checkpoint... 
Iteration: 993361250, states[0] = -42.401215, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1007827210, states[0] = -2.091727, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1022128243, states[0] = -62.901964, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1036181147, states[0] = -84.456712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050003427, states[0] = 32.564410, states[40]= 0.687036
Saving checkpoint... 
Iteration: 1064012781, states[0] = 31.265058, states[40]= 0.024200
Saving checkpoint... 
Iteration: 1079127702, states[0] = -62.192236, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1094324206, states[0] = 0.598240, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1109515600, states[0] = 31.380675, states[40]= 0.008706
Saving checkpoint... 
Iteration: 1124839182, states[0] = -15.823811, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1140151459, states[0] = -83.770383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155552249, states[0] = 15.594061, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1170932244, states[0] = -84.461516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186323283, states[0] = 1.373712, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1201853612, states[0] = -33.458308, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1217357346, states[0] = -37.838052, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1232800492, states[0] = 16.611090, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1248342464, states[0] = -19.958195, states[40]= 0.000165
Saving checkpoint... 
Iteration: 1263650817, states[0] = -83.688334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279090273, states[0] = -17.197737, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1294395891, states[0] = -82.512145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309793243, states[0] = 20.617869, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1325139505, states[0] = -77.825927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340468839, states[0] = -84.708617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355945625, states[0] = -84.562944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371385347, states[0] = -72.562325, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1386879931, states[0] = -65.105990, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1402336825, states[0] = -12.833494, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1417771969, states[0] = 30.196227, states[40]= 0.000879
Saving checkpoint... 
Iteration: 1433170567, states[0] = -84.338586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448612221, states[0] = -43.507022, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1464128927, states[0] = -63.761913, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1479645354, states[0] = -82.274528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494767859, states[0] = 31.155534, states[40]= 0.003848
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.709817
 - CaMKt in component CaMK (millimolar): 0.082324
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 6.995643
 - nass in component intracellular_ions (millimolar): 6.995846
 - ki in component intracellular_ions (millimolar): 144.482072
 - kss in component intracellular_ions (millimolar): 144.482041
 - cansr in component intracellular_ions (millimolar): 2.469859
 - cajsr in component intracellular_ions (millimolar): 1.900692
 - cai in component intracellular_ions (millimolar): 0.000119
 - m in component INa (dimensionless): 0.010095
 - hf in component INa (dimensionless): 0.578778
 - hs in component INa (dimensionless): 0.578419
 - j in component INa (dimensionless): 0.576154
 - hsp in component INa (dimensionless): 0.330518
 - jp in component INa (dimensionless): 0.572318
 - mL in component INaL (dimensionless): 0.000344
 - hL in component INaL (dimensionless): 0.293082
 - hLp in component INaL (dimensionless): 0.122682
 - a in component Ito (dimensionless): 0.001239
 - iF in component Ito (dimensionless): 0.999222
 - iS in component Ito (dimensionless): 0.253317
 - ap in component Ito (dimensionless): 0.000632
 - iFp in component Ito (dimensionless): 0.999222
 - iSp in component Ito (dimensionless): 0.280225
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.781439
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.981555
 - jca in component ICaL (dimensionless): 0.986236
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010602
 - xrf in component IKr (dimensionless): 0.007029
 - xrs in component IKr (dimensionless): 0.771956
 - xs1 in component IKs (dimensionless): 0.464252
 - xs2 in component IKs (dimensionless): 0.000352
 - xk1 in component IK1 (dimensionless): 0.996753
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
16:55:20 (1964): called boinc_finish(0)

</stderr_txt>
]]>


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