𝕏

Task 56166673

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_574_1
Workunit 26674904
Created 4 Jul 2024, 21:16:43 UTC
Sent 5 Jul 2024, 6:09:33 UTC
Report deadline 8 Jul 2024, 6:09:33 UTC
Received 5 Jul 2024, 23:26:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224482
Run time 1 hours 56 min 45 sec
CPU time 1 hours 56 min 9 sec
Validate state Valid
Credit 46.26
Device peak FLOPS 2.90 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.38 MB
Peak swap size 6.14 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_574.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_574_1_r1044848286_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_574_1_r1044848286_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.030773
     * GNaL_b in INaL: 0.005876
     * Gto_b in Ito: 0.084238
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031889
     * GKs_b in IKs: 0.001923
     * GK1_b in IK1: 0.162823
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.263021
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032217
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5003136, states[0] = -94.409068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12334617, states[0] = -94.216655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19738160, states[0] = -94.281429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26998989, states[0] = -94.278039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34185209, states[0] = -88.156849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41313767, states[0] = -94.248582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48609491, states[0] = -94.267363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55802056, states[0] = -94.234669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62994084, states[0] = -94.259637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70164898, states[0] = -61.022739, states[40]= 0.000023
Saving checkpoint... 
Iteration: 77267493, states[0] = -94.252745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84262477, states[0] = -93.912478, states[40]= 0.000000
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Iteration: 91321127, states[0] = -94.254602, states[40]= 0.000000
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Iteration: 98362567, states[0] = -94.169948, states[40]= 0.000000
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Iteration: 105333256, states[0] = -94.257090, states[40]= 0.000000
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Iteration: 112501468, states[0] = -94.265265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119580325, states[0] = -94.252522, states[40]= 0.000000
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Iteration: 126557700, states[0] = -94.277857, states[40]= 0.000000
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Iteration: 133522915, states[0] = -94.255339, states[40]= 0.000000
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Iteration: 140642470, states[0] = -94.284877, states[40]= 0.000000
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Iteration: 147748647, states[0] = -94.251354, states[40]= 0.000000
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Iteration: 154685873, states[0] = -94.285994, states[40]= 0.000000
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Iteration: 161765155, states[0] = -94.251641, states[40]= 0.000000
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Iteration: 168866892, states[0] = -94.280892, states[40]= 0.000000
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Iteration: 175915949, states[0] = -94.249390, states[40]= 0.000000
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Iteration: 182698083, states[0] = -94.286623, states[40]= 0.000000
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Iteration: 189744421, states[0] = -94.252581, states[40]= 0.000000
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Iteration: 196907128, states[0] = -94.279497, states[40]= 0.000000
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Iteration: 203916507, states[0] = -94.249640, states[40]= 0.000000
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Iteration: 210866476, states[0] = -94.281321, states[40]= 0.000000
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Iteration: 217724448, states[0] = -94.253038, states[40]= 0.000000
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Iteration: 224808366, states[0] = -94.283700, states[40]= 0.000000
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Iteration: 231870752, states[0] = -94.250320, states[40]= 0.000000
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Iteration: 238912910, states[0] = -94.279151, states[40]= 0.000000
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Iteration: 245827484, states[0] = -94.250964, states[40]= 0.000000
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Iteration: 252960014, states[0] = -94.276934, states[40]= 0.000000
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Iteration: 260076319, states[0] = 16.275079, states[40]= 0.000007
Saving checkpoint... 
Iteration: 267108068, states[0] = -94.270488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274169485, states[0] = -68.480676, states[40]= 0.000009
Saving checkpoint... 
Iteration: 281129529, states[0] = -94.269493, states[40]= 0.000000
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Iteration: 288200153, states[0] = -93.520224, states[40]= 0.000000
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Iteration: 295259981, states[0] = -94.264561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302329901, states[0] = -94.123565, states[40]= 0.000000
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Iteration: 309223627, states[0] = -94.265664, states[40]= 0.000000
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Iteration: 316315529, states[0] = -94.093025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323425405, states[0] = -94.259125, states[40]= 0.000000
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Iteration: 330382241, states[0] = -94.199345, states[40]= 0.000000
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Iteration: 337363293, states[0] = -94.260763, states[40]= 0.000000
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Iteration: 344405822, states[0] = -94.221144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351540106, states[0] = -94.255788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358586019, states[0] = -94.282236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365757462, states[0] = -94.250921, states[40]= 0.000000
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Iteration: 372962059, states[0] = -94.275495, states[40]= 0.000000
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Iteration: 380180267, states[0] = -85.331256, states[40]= 0.000001
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Iteration: 387387233, states[0] = -94.259446, states[40]= 0.000000
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Iteration: 394538653, states[0] = -94.275979, states[40]= 0.000000
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Iteration: 401605695, states[0] = -94.253634, states[40]= 0.000000
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Iteration: 408918463, states[0] = -94.277006, states[40]= 0.000000
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Iteration: 416066750, states[0] = 20.112412, states[40]= 0.000002
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Iteration: 423150466, states[0] = -94.266990, states[40]= 0.000000
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Iteration: 430295935, states[0] = -94.040883, states[40]= 0.000000
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Iteration: 437401303, states[0] = -94.258423, states[40]= 0.000000
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Iteration: 444548683, states[0] = -94.276948, states[40]= 0.000000
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Iteration: 451564278, states[0] = -94.253981, states[40]= 0.000000
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Iteration: 458401041, states[0] = -94.215755, states[40]= 0.000000
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Iteration: 465427738, states[0] = -94.257330, states[40]= 0.000000
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Iteration: 472607301, states[0] = -94.282332, states[40]= 0.000000
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Iteration: 479718080, states[0] = -94.250289, states[40]= 0.000000
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Iteration: 486737738, states[0] = -94.283089, states[40]= 0.000000
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Iteration: 493792299, states[0] = -94.248703, states[40]= 0.000000
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Iteration: 500902426, states[0] = -94.276597, states[40]= 0.000000
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Iteration: 507959699, states[0] = -94.245743, states[40]= 0.000000
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Iteration: 515094515, states[0] = -94.268077, states[40]= 0.000000
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Iteration: 522213698, states[0] = -93.637049, states[40]= 0.000000
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Iteration: 529151474, states[0] = -94.265652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536153682, states[0] = -49.669389, states[40]= 0.000104
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Iteration: 543251658, states[0] = -94.261836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550405296, states[0] = -94.218188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557415831, states[0] = -94.256533, states[40]= 0.000000
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Iteration: 564430782, states[0] = -94.236132, states[40]= 0.000000
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Iteration: 571477395, states[0] = -94.254679, states[40]= 0.000000
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Iteration: 578558812, states[0] = -94.276692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585473865, states[0] = -94.254600, states[40]= 0.000000
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Iteration: 592504425, states[0] = -94.266296, states[40]= 0.000000
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Iteration: 599499897, states[0] = -94.253749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606360868, states[0] = -94.170267, states[40]= 0.000000
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Iteration: 613487010, states[0] = -94.253909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620523128, states[0] = -94.270302, states[40]= 0.000000
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Iteration: 627453210, states[0] = -94.254634, states[40]= 0.000000
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Iteration: 634499577, states[0] = -94.264478, states[40]= 0.000000
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Iteration: 641578763, states[0] = -94.251300, states[40]= 0.000000
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Iteration: 648575342, states[0] = -94.277705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655588807, states[0] = -94.250896, states[40]= 0.000000
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Iteration: 660758005, states[0] = -94.280392, states[40]= 0.000000
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Iteration: 667819976, states[0] = -94.246061, states[40]= 0.000000
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Iteration: 674862289, states[0] = -94.276226, states[40]= 0.000000
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Iteration: 681799062, states[0] = -94.246263, states[40]= 0.000000
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Iteration: 688852780, states[0] = -94.276464, states[40]= 0.000000
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Iteration: 695937317, states[0] = -94.243769, states[40]= 0.000000
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Iteration: 702951773, states[0] = -94.271904, states[40]= 0.000000
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Iteration: 709868170, states[0] = -94.244713, states[40]= 0.000000
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Iteration: 716882608, states[0] = -94.274821, states[40]= 0.000000
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Iteration: 723942583, states[0] = -94.243342, states[40]= 0.000000
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Iteration: 731322634, states[0] = -94.257182, states[40]= 0.000000
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Iteration: 738625757, states[0] = -94.279934, states[40]= 0.000000
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Iteration: 745729792, states[0] = -94.246780, states[40]= 0.000000
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Iteration: 752940318, states[0] = -94.271800, states[40]= 0.000000
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Iteration: 759961470, states[0] = -94.242608, states[40]= 0.000000
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Iteration: 767111288, states[0] = -94.264297, states[40]= 0.000000
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Iteration: 774316786, states[0] = -94.090228, states[40]= 0.000000
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Iteration: 781410933, states[0] = -94.253913, states[40]= 0.000000
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Iteration: 788513688, states[0] = -94.266168, states[40]= 0.000000
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Iteration: 795509475, states[0] = -94.251091, states[40]= 0.000000
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Iteration: 802524152, states[0] = -94.268275, states[40]= 0.000000
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Iteration: 809515508, states[0] = -94.250765, states[40]= 0.000000
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Iteration: 816549161, states[0] = -94.272449, states[40]= 0.000000
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Iteration: 823660348, states[0] = -94.247239, states[40]= 0.000000
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Iteration: 830742062, states[0] = -94.278752, states[40]= 0.000000
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Iteration: 837660467, states[0] = -94.247065, states[40]= 0.000000
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Iteration: 844604204, states[0] = -94.277583, states[40]= 0.000000
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Iteration: 851563570, states[0] = -94.249075, states[40]= 0.000000
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Iteration: 858540819, states[0] = -94.270645, states[40]= 0.000000
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Iteration: 865525222, states[0] = -94.249837, states[40]= 0.000000
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Iteration: 872494430, states[0] = -94.260090, states[40]= 0.000000
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Iteration: 879462646, states[0] = -94.251281, states[40]= 0.000000
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Iteration: 886348043, states[0] = -94.148084, states[40]= 0.000000
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Iteration: 893256518, states[0] = -94.257364, states[40]= 0.000000
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Iteration: 900269386, states[0] = -93.943992, states[40]= 0.000000
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Iteration: 907257915, states[0] = -94.257144, states[40]= 0.000000
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Iteration: 914256937, states[0] = -93.889955, states[40]= 0.000000
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Iteration: 921289130, states[0] = -94.255925, states[40]= 0.000000
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Iteration: 928367165, states[0] = -94.174521, states[40]= 0.000000
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Iteration: 935418288, states[0] = -94.251812, states[40]= 0.000000
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Iteration: 942686301, states[0] = -94.278301, states[40]= 0.000000
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Iteration: 949656302, states[0] = -94.245776, states[40]= 0.000000
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Iteration: 957063170, states[0] = -94.263934, states[40]= 0.000000
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Iteration: 964232866, states[0] = -93.760055, states[40]= 0.000000
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Iteration: 971241295, states[0] = -94.256930, states[40]= 0.000000
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Iteration: 978395994, states[0] = -94.204891, states[40]= 0.000000
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Iteration: 985475199, states[0] = -94.249643, states[40]= 0.000000
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Iteration: 992619866, states[0] = -94.276580, states[40]= 0.000000
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Iteration: 999688775, states[0] = -94.244481, states[40]= 0.000000
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Iteration: 1006776199, states[0] = -94.275560, states[40]= 0.000000
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Iteration: 1013802801, states[0] = -94.242108, states[40]= 0.000000
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Iteration: 1020915978, states[0] = -94.269602, states[40]= 0.000000
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Iteration: 1028045533, states[0] = 25.663115, states[40]= 0.000000
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Iteration: 1035200050, states[0] = -94.257612, states[40]= 0.000000
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Iteration: 1042182978, states[0] = -88.978467, states[40]= 0.000000
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Iteration: 1064179855, states[0] = -84.640009, states[40]= 0.000001
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Iteration: 1071092318, states[0] = -94.261328, states[40]= 0.000000
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Iteration: 1078048225, states[0] = 25.231102, states[40]= 0.000000
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Iteration: 1085182430, states[0] = -94.257643, states[40]= 0.000000
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Iteration: 1092229964, states[0] = -93.740409, states[40]= 0.000000
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Iteration: 1099347104, states[0] = -94.251892, states[40]= 0.000000
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Iteration: 1106485400, states[0] = -94.254410, states[40]= 0.000000
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Iteration: 1113651646, states[0] = -94.243856, states[40]= 0.000000
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Iteration: 1141641951, states[0] = -94.243721, states[40]= 0.000000
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Iteration: 1148667866, states[0] = -94.275769, states[40]= 0.000000
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Iteration: 1162624147, states[0] = -94.274669, states[40]= 0.000000
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Iteration: 1204821510, states[0] = -94.271432, states[40]= 0.000000
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Iteration: 1211885488, states[0] = -94.238244, states[40]= 0.000000
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Iteration: 1219019935, states[0] = -94.262556, states[40]= 0.000000
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Iteration: 1226097698, states[0] = 5.300833, states[40]= 0.000087
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Iteration: 1233104902, states[0] = -94.258826, states[40]= 0.000000
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Iteration: 1240104707, states[0] = 0.796395, states[40]= 0.000167
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Iteration: 1247199260, states[0] = -94.255030, states[40]= 0.000000
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Iteration: 1254260530, states[0] = -93.902061, states[40]= 0.000000
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Iteration: 1261282779, states[0] = -94.251952, states[40]= 0.000000
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Iteration: 1268254805, states[0] = -93.875441, states[40]= 0.000000
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Iteration: 1282349825, states[0] = -94.145956, states[40]= 0.000000
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Iteration: 1289283459, states[0] = -94.251584, states[40]= 0.000000
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Iteration: 1296282279, states[0] = -93.986909, states[40]= 0.000000
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Iteration: 1303361996, states[0] = -94.248926, states[40]= 0.000000
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Iteration: 1310485810, states[0] = -94.252035, states[40]= 0.000000
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Iteration: 1317435025, states[0] = -94.246640, states[40]= 0.000000
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Iteration: 1324561503, states[0] = -94.267869, states[40]= 0.000000
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Iteration: 1331713530, states[0] = -94.239888, states[40]= 0.000000
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Iteration: 1338920106, states[0] = -94.265508, states[40]= 0.000000
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Iteration: 1346202110, states[0] = -93.530515, states[40]= 0.000000
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Iteration: 1353120931, states[0] = -94.256710, states[40]= 0.000000
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Iteration: 1360207778, states[0] = -93.581523, states[40]= 0.000000
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Iteration: 1367319117, states[0] = -94.249469, states[40]= 0.000000
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Iteration: 1374389945, states[0] = -94.194318, states[40]= 0.000000
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Iteration: 1381513022, states[0] = -94.243791, states[40]= 0.000000
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Iteration: 1388537286, states[0] = -94.263543, states[40]= 0.000000
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Iteration: 1395543988, states[0] = -94.242850, states[40]= 0.000000
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Iteration: 1402655622, states[0] = -94.272535, states[40]= 0.000000
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Iteration: 1409774830, states[0] = -94.237743, states[40]= 0.000000
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Iteration: 1416700882, states[0] = -94.272360, states[40]= 0.000000
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Iteration: 1423739028, states[0] = -94.238251, states[40]= 0.000000
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Iteration: 1444716982, states[0] = -94.271773, states[40]= 0.000000
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Iteration: 1451769115, states[0] = -94.237330, states[40]= 0.000000
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Iteration: 1458865954, states[0] = -94.266434, states[40]= 0.000000
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Iteration: 1465927853, states[0] = -94.234429, states[40]= 0.000000
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Iteration: 1472891898, states[0] = -94.265119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479947714, states[0] = -94.233948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484915487, states[0] = -94.263918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492005328, states[0] = 15.312347, states[40]= 0.578661
Saving checkpoint... 
Iteration: 1499068216, states[0] = -94.257056, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.108890
 - CaMKt in component CaMK (millimolar): 0.002335
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.149714
 - nass in component intracellular_ions (millimolar): 7.149852
 - ki in component intracellular_ions (millimolar): 144.522855
 - kss in component intracellular_ions (millimolar): 144.522840
 - cansr in component intracellular_ions (millimolar): 2.420517
 - cajsr in component intracellular_ions (millimolar): 2.420981
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003920
 - hf in component INa (dimensionless): 0.865545
 - hs in component INa (dimensionless): 0.865546
 - j in component INa (dimensionless): 0.865549
 - hsp in component INa (dimensionless): 0.699184
 - jp in component INa (dimensionless): 0.865551
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707793
 - hLp in component INaL (dimensionless): 0.513753
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996755
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005326
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006689
 - xs1 in component IKs (dimensionless): 0.039638
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997538
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:29:12 (8076): called boinc_finish(0)

</stderr_txt>
]]>


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