𝕏

Task 56166669

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_374_1
Workunit 26674902
Created 4 Jul 2024, 21:16:43 UTC
Sent 5 Jul 2024, 6:09:33 UTC
Report deadline 8 Jul 2024, 6:09:33 UTC
Received 6 Jul 2024, 3:31:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224482
Run time 1 hours 56 min 34 sec
CPU time 1 hours 55 min 24 sec
Validate state Valid
Credit 43.93
Device peak FLOPS 2.90 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.38 MB
Peak swap size 6.13 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_374.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_374_1_r1256473808_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_4000-conf_374_1_r1256473808_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.408194
     * GNaL_b in INaL: 0.005918
     * Gto_b in Ito: 0.084070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031719
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.163498
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.535293
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033920
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 2517365, states[0] = -94.445302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 9424754, states[0] = -94.362074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16466656, states[0] = -94.302890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23684186, states[0] = -94.277428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30900989, states[0] = -94.283610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38136213, states[0] = -26.354381, states[40]= 0.000281
Saving checkpoint... 
Iteration: 45439993, states[0] = -94.252637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52656130, states[0] = -94.277861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59812761, states[0] = -94.244298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67057690, states[0] = -94.266899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74187456, states[0] = -91.430633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81361457, states[0] = -94.259830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88362647, states[0] = -94.177106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95433570, states[0] = -94.261081, states[40]= 0.000000
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Iteration: 102540524, states[0] = -94.280477, states[40]= 0.000000
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Iteration: 109631394, states[0] = -94.258821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116606654, states[0] = -94.289570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123554910, states[0] = -94.262370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130629852, states[0] = -94.292120, states[40]= 0.000000
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Iteration: 137713238, states[0] = -94.260186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144806473, states[0] = -94.290854, states[40]= 0.000000
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Iteration: 151775866, states[0] = -94.259802, states[40]= 0.000000
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Iteration: 158936239, states[0] = -94.285974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166017823, states[0] = 24.021123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173118226, states[0] = -94.278661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180110915, states[0] = -3.705629, states[40]= 0.000247
Saving checkpoint... 
Iteration: 187160243, states[0] = -94.277251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194366633, states[0] = -94.191219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201398071, states[0] = -94.269497, states[40]= 0.000000
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Iteration: 208444866, states[0] = -94.256563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215513568, states[0] = -94.266411, states[40]= 0.000000
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Iteration: 223014368, states[0] = -94.283206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230270035, states[0] = -93.965263, states[40]= 0.000000
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Iteration: 237246701, states[0] = -94.274134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244328507, states[0] = -94.130811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251382680, states[0] = -94.269733, states[40]= 0.000000
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Iteration: 258585237, states[0] = -94.291586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265817734, states[0] = -94.259675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272781819, states[0] = -94.292646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279779095, states[0] = -94.260228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286868963, states[0] = -94.289044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292709324, states[0] = -94.294315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299856391, states[0] = -94.258651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301230803, states[0] = -94.274066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309555631, states[0] = -94.264574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316484005, states[0] = -94.272037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323672561, states[0] = -94.261813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330932017, states[0] = -94.285773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338043369, states[0] = 25.961097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345246392, states[0] = -94.273015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352403934, states[0] = -94.228197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359576054, states[0] = -94.263503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366673338, states[0] = -94.293688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373825043, states[0] = -94.258313, states[40]= 0.000000
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Iteration: 381022934, states[0] = -94.281202, states[40]= 0.000000
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Iteration: 388234287, states[0] = -93.787750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395251924, states[0] = -94.272224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402385429, states[0] = -94.210619, states[40]= 0.000000
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Iteration: 409386142, states[0] = -94.267834, states[40]= 0.000000
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Iteration: 416312586, states[0] = -94.094561, states[40]= 0.000000
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Iteration: 423340725, states[0] = -94.269018, states[40]= 0.000000
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Iteration: 430377122, states[0] = -94.201422, states[40]= 0.000000
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Iteration: 437488841, states[0] = -94.264688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444538517, states[0] = -94.283679, states[40]= 0.000000
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Iteration: 449479703, states[0] = -94.264778, states[40]= 0.000000
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Iteration: 456525120, states[0] = -94.281072, states[40]= 0.000000
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Iteration: 463451171, states[0] = -94.265361, states[40]= 0.000000
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Iteration: 470390540, states[0] = -94.214837, states[40]= 0.000000
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Iteration: 476936525, states[0] = -94.283808, states[40]= 0.000000
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Iteration: 483785118, states[0] = -94.257684, states[40]= 0.000000
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Iteration: 490648081, states[0] = -94.291915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497654436, states[0] = -94.260084, states[40]= 0.000000
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Iteration: 504723583, states[0] = -94.291523, states[40]= 0.000000
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Iteration: 511555175, states[0] = -94.262142, states[40]= 0.000000
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Iteration: 518468473, states[0] = -94.263962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525486414, states[0] = -94.263674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532533608, states[0] = -94.281752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539759486, states[0] = -94.257474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546996342, states[0] = -94.280324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554291149, states[0] = -94.035072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561428691, states[0] = -94.264775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568502537, states[0] = -94.274484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575602061, states[0] = -94.260276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582759327, states[0] = -94.289669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589916421, states[0] = -94.254164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597027719, states[0] = -94.278367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602893369, states[0] = -94.284180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609954063, states[0] = -94.253341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617031442, states[0] = -94.277967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623983580, states[0] = -94.252733, states[40]= 0.000000
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Iteration: 630904254, states[0] = -94.283361, states[40]= 0.000000
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Iteration: 639937602, states[0] = -94.253225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646975478, states[0] = -94.280018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653966548, states[0] = -94.252615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661028321, states[0] = -94.277560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666744387, states[0] = -94.289066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673624912, states[0] = -94.258570, states[40]= 0.000000
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Iteration: 680648742, states[0] = -94.289613, states[40]= 0.000000
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Iteration: 687630943, states[0] = -94.258268, states[40]= 0.000000
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Iteration: 694607486, states[0] = -94.287941, states[40]= 0.000000
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Iteration: 701506440, states[0] = -94.261014, states[40]= 0.000000
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Iteration: 708418427, states[0] = -94.234882, states[40]= 0.000000
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Iteration: 715514708, states[0] = -94.260635, states[40]= 0.000000
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Iteration: 722669629, states[0] = -94.289341, states[40]= 0.000000
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Iteration: 727559846, states[0] = -94.259392, states[40]= 0.000000
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Iteration: 734572905, states[0] = -94.284738, states[40]= 0.000000
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Iteration: 741591751, states[0] = -94.258480, states[40]= 0.000000
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Iteration: 748721323, states[0] = -94.288594, states[40]= 0.000000
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Iteration: 755898790, states[0] = -94.252413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763044625, states[0] = -94.275625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770116663, states[0] = -8.922484, states[40]= 0.000283
Saving checkpoint... 
Iteration: 777299430, states[0] = -94.265992, states[40]= 0.000000
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Iteration: 784685970, states[0] = -94.288588, states[40]= 0.000000
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Iteration: 791727979, states[0] = -94.254998, states[40]= 0.000000
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Iteration: 798768756, states[0] = -94.286744, states[40]= 0.000000
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Iteration: 805873132, states[0] = -94.252221, states[40]= 0.000000
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Iteration: 812875350, states[0] = -94.282405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820033482, states[0] = 26.417294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826932627, states[0] = -94.279714, states[40]= 0.000000
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Iteration: 833874580, states[0] = -94.251856, states[40]= 0.000000
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Iteration: 840892163, states[0] = -94.281330, states[40]= 0.000000
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Iteration: 847972497, states[0] = -94.250154, states[40]= 0.000000
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Iteration: 853958174, states[0] = -94.250294, states[40]= 0.000000
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Iteration: 860910550, states[0] = -94.280274, states[40]= 0.000000
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Iteration: 867997445, states[0] = -94.249544, states[40]= 0.000000
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Iteration: 874955847, states[0] = -94.278098, states[40]= 0.000000
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Iteration: 882028198, states[0] = 26.058763, states[40]= 0.000000
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Iteration: 886821908, states[0] = -94.283737, states[40]= 0.000000
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Iteration: 893880397, states[0] = -94.251024, states[40]= 0.000000
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Iteration: 900909854, states[0] = -94.279816, states[40]= 0.000000
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Iteration: 908046761, states[0] = 25.497992, states[40]= 0.000000
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Iteration: 915035132, states[0] = -94.274170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922006130, states[0] = 16.761017, states[40]= -0.000004
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Iteration: 929055976, states[0] = -94.273124, states[40]= 0.000000
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Iteration: 936508684, states[0] = -94.271564, states[40]= 0.000000
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Iteration: 943685228, states[0] = -94.253992, states[40]= 0.000000
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Iteration: 950830683, states[0] = -94.282604, states[40]= 0.000000
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Iteration: 957957772, states[0] = -94.249028, states[40]= 0.000000
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Iteration: 965132076, states[0] = -94.269625, states[40]= 0.000000
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Iteration: 972200335, states[0] = -93.526101, states[40]= 0.000000
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Iteration: 979319990, states[0] = -94.262872, states[40]= 0.000000
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Iteration: 986451625, states[0] = -94.250882, states[40]= 0.000000
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Iteration: 993522609, states[0] = -94.257045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000598139, states[0] = -94.283634, states[40]= 0.000000
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Iteration: 1007585736, states[0] = -94.255370, states[40]= 0.000000
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Iteration: 1011995797, states[0] = -94.247810, states[40]= 0.000000
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Iteration: 1019061846, states[0] = -94.271785, states[40]= 0.000000
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Iteration: 1025974692, states[0] = -94.247946, states[40]= 0.000000
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Iteration: 1032877119, states[0] = -94.279646, states[40]= 0.000000
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Iteration: 1040001986, states[0] = 26.153168, states[40]= 1.972561
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Iteration: 1047109015, states[0] = -94.269531, states[40]= 0.000000
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Iteration: 1053250843, states[0] = -94.264232, states[40]= 0.000000
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Iteration: 1060244110, states[0] = -93.835073, states[40]= 0.000000
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Iteration: 1067371949, states[0] = -94.260218, states[40]= 0.000000
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Iteration: 1074359683, states[0] = -94.171974, states[40]= 0.000000
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Iteration: 1081247737, states[0] = -94.263996, states[40]= 0.000000
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Iteration: 1088142339, states[0] = -36.102125, states[40]= 0.000365
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Iteration: 1095161283, states[0] = -94.266926, states[40]= 0.000000
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Iteration: 1102114867, states[0] = -7.207480, states[40]= 0.000280
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Iteration: 1109117124, states[0] = -94.268456, states[40]= 0.000000
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Iteration: 1116182871, states[0] = -88.500135, states[40]= 0.000000
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Iteration: 1123246980, states[0] = -94.263511, states[40]= 0.000000
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Iteration: 1129423126, states[0] = -94.257995, states[40]= 0.000000
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Iteration: 1135052688, states[0] = -94.270753, states[40]= 0.000000
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Iteration: 1140595278, states[0] = -94.281732, states[40]= 0.000000
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Iteration: 1147390096, states[0] = -94.258711, states[40]= 0.000000
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Iteration: 1154364904, states[0] = -94.177905, states[40]= 0.000000
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Iteration: 1161444089, states[0] = -94.257027, states[40]= 0.000000
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Iteration: 1168373475, states[0] = -94.188224, states[40]= 0.000000
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Iteration: 1175235261, states[0] = -94.263277, states[40]= 0.000000
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Iteration: 1182234585, states[0] = -93.779553, states[40]= 0.000000
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Iteration: 1189283829, states[0] = -94.261469, states[40]= 0.000000
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Iteration: 1196391872, states[0] = -94.207224, states[40]= 0.000000
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Iteration: 1203325813, states[0] = -94.259956, states[40]= 0.000000
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Iteration: 1210224216, states[0] = -93.713957, states[40]= 0.000000
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Iteration: 1217317119, states[0] = -94.260057, states[40]= 0.000000
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Iteration: 1224352147, states[0] = -94.159394, states[40]= 0.000000
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Iteration: 1231376998, states[0] = -94.258066, states[40]= 0.000000
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Iteration: 1238317011, states[0] = -94.094626, states[40]= 0.000000
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Iteration: 1245305194, states[0] = -94.260095, states[40]= 0.000000
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Iteration: 1252428463, states[0] = -94.234888, states[40]= 0.000000
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Iteration: 1259513246, states[0] = -94.254030, states[40]= 0.000000
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Iteration: 1266442574, states[0] = -94.242879, states[40]= 0.000000
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Iteration: 1273085572, states[0] = -94.267716, states[40]= 0.000000
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Iteration: 1280375789, states[0] = -94.189515, states[40]= 0.000000
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Iteration: 1287565455, states[0] = -94.252424, states[40]= 0.000000
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Iteration: 1292728686, states[0] = -94.281821, states[40]= 0.000000
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Iteration: 1299782416, states[0] = -94.247767, states[40]= 0.000000
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Iteration: 1306755419, states[0] = -94.280966, states[40]= 0.000000
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Iteration: 1313871494, states[0] = -94.246043, states[40]= 0.000000
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Iteration: 1320966428, states[0] = -94.272197, states[40]= 0.000000
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Iteration: 1328038346, states[0] = 26.371169, states[40]= 0.000000
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Iteration: 1334845577, states[0] = -94.277312, states[40]= 0.000000
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Iteration: 1341989642, states[0] = -94.243865, states[40]= 0.000000
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Iteration: 1349380025, states[0] = -94.256535, states[40]= 0.000000
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Iteration: 1356905075, states[0] = -94.274471, states[40]= 0.000000
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Iteration: 1364176539, states[0] = -78.482219, states[40]= 0.000002
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Iteration: 1371549080, states[0] = -94.251783, states[40]= 0.000000
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Iteration: 1378927035, states[0] = -94.273230, states[40]= 0.000000
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Iteration: 1386138011, states[0] = -31.329779, states[40]= 0.000442
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Iteration: 1393260822, states[0] = -94.259742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398087139, states[0] = 11.200497, states[40]= 0.000027
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Iteration: 1405348374, states[0] = -94.256795, states[40]= 0.000000
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Iteration: 1412606779, states[0] = -94.279154, states[40]= 0.000000
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Iteration: 1419719133, states[0] = -94.247497, states[40]= 0.000000
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Iteration: 1426771637, states[0] = -94.278998, states[40]= 0.000000
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Iteration: 1433949510, states[0] = -94.243335, states[40]= 0.000000
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Iteration: 1441162057, states[0] = -94.262673, states[40]= 0.000000
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Iteration: 1448345428, states[0] = -94.146249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455412907, states[0] = -94.254298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460407638, states[0] = -94.217653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468290048, states[0] = -94.020370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475499501, states[0] = -94.251738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483280476, states[0] = -94.257991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491294004, states[0] = -94.257452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492463345, states[0] = -94.249988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493697277, states[0] = -94.247031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497668552, states[0] = -94.247572, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.117755
 - CaMKt in component CaMK (millimolar): 0.002328
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.140306
 - nass in component intracellular_ions (millimolar): 7.140443
 - ki in component intracellular_ions (millimolar): 144.533913
 - kss in component intracellular_ions (millimolar): 144.533898
 - cansr in component intracellular_ions (millimolar): 2.415634
 - cajsr in component intracellular_ions (millimolar): 2.416092
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003917
 - hf in component INa (dimensionless): 0.865714
 - hs in component INa (dimensionless): 0.865715
 - j in component INa (dimensionless): 0.865718
 - hsp in component INa (dimensionless): 0.699490
 - jp in component INa (dimensionless): 0.865720
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.708037
 - hLp in component INaL (dimensionless): 0.514046
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996748
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005288
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006689
 - xs1 in component IKs (dimensionless): 0.039711
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997536
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:08:16 (6232): called boinc_finish(0)

</stderr_txt>
]]>


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