𝕏

Task 56165368

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_273_0
Workunit 26674252
Created 4 Jul 2024, 21:16:06 UTC
Sent 5 Jul 2024, 6:00:02 UTC
Report deadline 8 Jul 2024, 6:00:02 UTC
Received 6 Jul 2024, 3:24:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215304
Run time 54 min 8 sec
CPU time 54 min 8 sec
Validate state Valid
Credit 44.78
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.78 MB
Peak swap size 6.23 MB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_273.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_273_0_r559302274_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_273_0_r559302274_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.272007
     * GNaL_b in INaL: 0.005763
     * Gto_b in Ito: 0.084907
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031740
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.163025
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.388697
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032422
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9163143, states[0] = -94.671377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19254153, states[0] = -94.596358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29296988, states[0] = -94.551669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39194907, states[0] = -94.525723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48765957, states[0] = -94.514991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58211684, states[0] = -94.509202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67417289, states[0] = -94.483967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76719601, states[0] = -94.483357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86008331, states[0] = -94.490650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96375884, states[0] = -94.479931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106174724, states[0] = -94.480972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115717306, states[0] = -94.483225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124999436, states[0] = -94.463234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134199011, states[0] = -94.468004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144622875, states[0] = -94.463118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154784341, states[0] = -94.461271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164775227, states[0] = -94.460701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174570369, states[0] = -94.461580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184130621, states[0] = -94.465461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193341480, states[0] = -94.478281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202886051, states[0] = -94.382321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212239440, states[0] = -94.459356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221429944, states[0] = -94.467425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230727309, states[0] = -94.476538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240953878, states[0] = -94.476150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251015900, states[0] = -94.474930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260853920, states[0] = -94.477274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270808472, states[0] = -94.477349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280054780, states[0] = 19.619718, states[40]= 0.002913
Saving checkpoint... 
Iteration: 289236977, states[0] = -94.462866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298452534, states[0] = -94.475872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309013507, states[0] = -94.465614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319168608, states[0] = -94.463568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329129249, states[0] = -94.464028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338810413, states[0] = -94.468833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348238651, states[0] = -94.476336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357543094, states[0] = 22.902607, states[40]= 0.002245
Saving checkpoint... 
Iteration: 366764570, states[0] = -94.462424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376981666, states[0] = -94.460388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386905273, states[0] = -94.461033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396688337, states[0] = -94.463238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406299374, states[0] = -94.468959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415662174, states[0] = -94.472966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424865185, states[0] = -94.457783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434073322, states[0] = -94.464637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443302326, states[0] = -94.477048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453938667, states[0] = -94.466568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463970697, states[0] = -94.466069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473687441, states[0] = -94.471042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483142532, states[0] = -94.471442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492425785, states[0] = -94.457415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501580341, states[0] = -94.464494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510788839, states[0] = -94.476931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520116063, states[0] = -9.969791, states[40]= 0.002508
Saving checkpoint... 
Iteration: 531770231, states[0] = -94.462232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541567853, states[0] = -94.464631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551256072, states[0] = -94.469654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560719147, states[0] = -94.475617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569958698, states[0] = -94.457195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579250010, states[0] = -94.462413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589416097, states[0] = -94.460784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599367858, states[0] = -94.461216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609207431, states[0] = -94.462862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618767317, states[0] = -94.469395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628070637, states[0] = -94.462541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637224164, states[0] = -94.458451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646411359, states[0] = -94.466863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655673386, states[0] = -94.473498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665706147, states[0] = -94.475080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675828355, states[0] = -94.476890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685732480, states[0] = -94.475919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695137226, states[0] = -26.932143, states[40]= 0.001545
Saving checkpoint... 
Iteration: 704256598, states[0] = -94.462254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713415097, states[0] = -94.476079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723630029, states[0] = -94.472022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733657444, states[0] = -94.471459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743550010, states[0] = -94.473636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753198685, states[0] = -94.474713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762718686, states[0] = -93.983842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772021762, states[0] = -94.459776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779102729, states[0] = -94.464006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787937332, states[0] = -94.418262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796812089, states[0] = -94.461616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805808922, states[0] = -94.476807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814645099, states[0] = -94.458843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823605653, states[0] = -94.472449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832400587, states[0] = -94.457304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841270424, states[0] = -94.469180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850375838, states[0] = -94.371225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859528215, states[0] = -94.459664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868658203, states[0] = -94.471348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877486613, states[0] = -94.456843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886391230, states[0] = -94.467023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895204563, states[0] = -92.211572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904106165, states[0] = -94.463874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913190573, states[0] = -94.474232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921856225, states[0] = -94.461098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930642233, states[0] = -94.471102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940322430, states[0] = -94.301319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949803689, states[0] = -94.457752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958521986, states[0] = -94.474042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967756159, states[0] = -94.145522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976623897, states[0] = -94.463598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985893712, states[0] = -94.476168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995464354, states[0] = -94.431766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004881694, states[0] = -94.457282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014260625, states[0] = -94.461993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023274978, states[0] = -94.476449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032424935, states[0] = -94.457038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041674357, states[0] = -94.462939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050855983, states[0] = -94.476491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060101499, states[0] = 0.063249, states[40]= 0.004377
Saving checkpoint... 
Iteration: 1069883596, states[0] = -94.457226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079210994, states[0] = -94.462490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088278714, states[0] = -94.476441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098458655, states[0] = -94.475120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107653856, states[0] = -40.275986, states[40]= 0.000429
Saving checkpoint... 
Iteration: 1117767496, states[0] = -94.179360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127728755, states[0] = -94.050128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137638342, states[0] = -27.806583, states[40]= 0.001499
Saving checkpoint... 
Iteration: 1147133686, states[0] = -94.458687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156318891, states[0] = -94.468074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165467224, states[0] = -94.432911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174587330, states[0] = -94.458997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185712369, states[0] = -94.474946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195627175, states[0] = -94.469553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205352580, states[0] = -94.344891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214694000, states[0] = -94.458236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223915755, states[0] = -94.466386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233316568, states[0] = -94.476512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242564739, states[0] = 16.410931, states[40]= 0.003535
Saving checkpoint... 
Iteration: 1252636141, states[0] = -26.082542, states[40]= 0.001573
Saving checkpoint... 
Iteration: 1262592457, states[0] = 4.917155, states[40]= 0.004594
Saving checkpoint... 
Iteration: 1272620216, states[0] = -13.315386, states[40]= 0.001898
Saving checkpoint... 
Iteration: 1282199440, states[0] = -94.458153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291405874, states[0] = -94.466498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300651363, states[0] = -94.471567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309841777, states[0] = -94.457283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320115607, states[0] = -9.610072, states[40]= 0.002584
Saving checkpoint... 
Iteration: 1330144554, states[0] = -32.717654, states[40]= 0.001055
Saving checkpoint... 
Iteration: 1339882481, states[0] = -94.457042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349450375, states[0] = -94.459951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358874650, states[0] = -94.466966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368614386, states[0] = -94.471887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378764560, states[0] = -94.468911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388754816, states[0] = -94.469087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398455404, states[0] = -94.474964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408055887, states[0] = -94.459305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417359206, states[0] = -94.457112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426675067, states[0] = -94.462659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435881301, states[0] = -94.475992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446079822, states[0] = -94.472538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456250579, states[0] = -94.469120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466569061, states[0] = -94.463963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476092005, states[0] = -94.472268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485381602, states[0] = -94.376401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494545189, states[0] = -94.459085, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.332316
 - CaMKt in component CaMK (millimolar): 0.001125
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.307782
 - nass in component intracellular_ions (millimolar): 6.307869
 - ki in component intracellular_ions (millimolar): 145.617471
 - kss in component intracellular_ions (millimolar): 145.617460
 - cansr in component intracellular_ions (millimolar): 1.566445
 - cajsr in component intracellular_ions (millimolar): 1.566482
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003833
 - hf in component INa (dimensionless): 0.869760
 - hs in component INa (dimensionless): 0.869760
 - j in component INa (dimensionless): 0.869761
 - hsp in component INa (dimensionless): 0.706846
 - jp in component INa (dimensionless): 0.869762
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713895
 - hLp in component INaL (dimensionless): 0.521512
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997754
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999256
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998867
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002995
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001786
 - xs1 in component IKs (dimensionless): 0.022769
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997483
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:44:46 (10096): called boinc_finish(0)

</stderr_txt>
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