𝕏

Task 56163709

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_371_0
Workunit 26673423
Created 4 Jul 2024, 21:15:19 UTC
Sent 5 Jul 2024, 5:55:49 UTC
Report deadline 8 Jul 2024, 5:55:49 UTC
Received 5 Jul 2024, 12:56:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224662
Run time 2 hours 30 min 52 sec
CPU time 2 hours 29 min 17 sec
Validate state Valid
Credit 44.28
Device peak FLOPS 1.89 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 1.30 MB
Peak swap size 3.68 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_371.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_371_0_r1796576252_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_371_0_r1796576252_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.223595
     * GNaL_b in INaL: 0.005908
     * Gto_b in Ito: 0.085458
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031972
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.164387
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.672254
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033153
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10348906, states[0] = 19.750653, states[40]= 0.016721
Saving checkpoint... 
Iteration: 20349581, states[0] = 19.212339, states[40]= 0.013476
Saving checkpoint... 
Iteration: 30298903, states[0] = -87.711035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40284125, states[0] = -87.608182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50241151, states[0] = -42.484830, states[40]= 0.000113
Saving checkpoint... 
Iteration: 60317569, states[0] = -87.792319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70098480, states[0] = -82.523649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80219159, states[0] = -16.152854, states[40]= 0.001830
Saving checkpoint... 
Iteration: 90096273, states[0] = -82.353321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99852267, states[0] = 13.727436, states[40]= 0.008231
Saving checkpoint... 
Iteration: 109651425, states[0] = -87.812511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119468361, states[0] = -87.765271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129838977, states[0] = 19.040117, states[40]= 0.012557
Saving checkpoint... 
Iteration: 139838600, states[0] = 18.764836, states[40]= 0.011938
Saving checkpoint... 
Iteration: 149931609, states[0] = -87.083041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159802946, states[0] = -87.783256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169750967, states[0] = -76.388820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179682092, states[0] = 10.924936, states[40]= 0.007691
Saving checkpoint... 
Iteration: 189556777, states[0] = -37.556197, states[40]= 0.000221
Saving checkpoint... 
Iteration: 199268092, states[0] = -87.619052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209131880, states[0] = -87.784963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219105772, states[0] = -87.684487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229153615, states[0] = 22.556866, states[40]= 0.048256
Saving checkpoint... 
Iteration: 239253265, states[0] = -86.365139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249122267, states[0] = -87.766467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259361960, states[0] = -8.067636, states[40]= 0.003849
Saving checkpoint... 
Iteration: 269299766, states[0] = -87.806666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279093275, states[0] = -87.615925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288937239, states[0] = -87.711039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299225851, states[0] = -56.446309, states[40]= 0.000014
Saving checkpoint... 
Iteration: 309333123, states[0] = 12.621391, states[40]= 0.007987
Saving checkpoint... 
Iteration: 319254771, states[0] = -87.590896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329630982, states[0] = -87.817502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339969208, states[0] = 33.007525, states[40]= 0.120042
Saving checkpoint... 
Iteration: 349828883, states[0] = 12.738683, states[40]= 0.008010
Saving checkpoint... 
Iteration: 360061750, states[0] = -70.235864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 369992517, states[0] = 13.356918, states[40]= 0.008144
Saving checkpoint... 
Iteration: 379840367, states[0] = 2.152342, states[40]= 0.006435
Saving checkpoint... 
Iteration: 389666714, states[0] = 7.001193, states[40]= 0.007152
Saving checkpoint... 
Iteration: 399761720, states[0] = -87.720537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409558014, states[0] = -72.357595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419645908, states[0] = 17.859838, states[40]= 0.010503
Saving checkpoint... 
Iteration: 429730928, states[0] = -84.429404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439652569, states[0] = 13.144670, states[40]= 0.008096
Saving checkpoint... 
Iteration: 449848679, states[0] = -15.982496, states[40]= 0.001862
Saving checkpoint... 
Iteration: 459746215, states[0] = -87.668925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469882493, states[0] = -67.484090, states[40]= 0.000003
Saving checkpoint... 
Iteration: 479945791, states[0] = -87.807555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489846002, states[0] = -17.865013, states[40]= 0.001549
Saving checkpoint... 
Iteration: 499895909, states[0] = -86.949885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510049851, states[0] = -75.670557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519828330, states[0] = 0.358963, states[40]= 0.006097
Saving checkpoint... 
Iteration: 529859294, states[0] = -41.992078, states[40]= 0.000122
Saving checkpoint... 
Iteration: 539806073, states[0] = 14.986223, states[40]= 0.008605
Saving checkpoint... 
Iteration: 549997283, states[0] = -5.256297, states[40]= 0.004685
Saving checkpoint... 
Iteration: 559855951, states[0] = -41.520267, states[40]= 0.000130
Saving checkpoint... 
Iteration: 569980357, states[0] = 8.209494, states[40]= 0.007310
Saving checkpoint... 
Iteration: 580215739, states[0] = -84.312623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590238252, states[0] = -87.700294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600321414, states[0] = -0.740802, states[40]= 0.005862
Saving checkpoint... 
Iteration: 610635217, states[0] = 13.297516, states[40]= 0.008129
Saving checkpoint... 
Iteration: 620685571, states[0] = -44.812875, states[40]= 0.000082
Saving checkpoint... 
Iteration: 630795179, states[0] = 15.971633, states[40]= 0.009021
Saving checkpoint... 
Iteration: 641003712, states[0] = -26.588827, states[40]= 0.000713
Saving checkpoint... 
Iteration: 650791152, states[0] = 17.027202, states[40]= 0.009687
Saving checkpoint... 
Iteration: 660977693, states[0] = 3.210515, states[40]= 0.006612
Saving checkpoint... 
Iteration: 671168736, states[0] = -28.510829, states[40]= 0.000599
Saving checkpoint... 
Iteration: 681600428, states[0] = 39.422098, states[40]= 0.080158
Saving checkpoint... 
Iteration: 692051098, states[0] = -87.597022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702284494, states[0] = 17.770610, states[40]= 0.010398
Saving checkpoint... 
Iteration: 712336399, states[0] = -35.590532, states[40]= 0.000281
Saving checkpoint... 
Iteration: 722204501, states[0] = -86.178390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732054644, states[0] = -87.684877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742328261, states[0] = -28.473240, states[40]= 0.000601
Saving checkpoint... 
Iteration: 752177858, states[0] = -52.516241, states[40]= 0.000026
Saving checkpoint... 
Iteration: 762226755, states[0] = -87.725378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772166329, states[0] = -39.142539, states[40]= 0.000180
Saving checkpoint... 
Iteration: 782374521, states[0] = -87.573845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792396890, states[0] = -87.750291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802091926, states[0] = 26.510372, states[40]= 0.112512
Saving checkpoint... 
Iteration: 812096770, states[0] = 21.921985, states[40]= 0.035847
Saving checkpoint... 
Iteration: 821968015, states[0] = -2.913504, states[40]= 0.005334
Saving checkpoint... 
Iteration: 832077361, states[0] = -87.807425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842364381, states[0] = -87.344932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852171266, states[0] = -57.502692, states[40]= 0.000012
Saving checkpoint... 
Iteration: 862075393, states[0] = -87.810287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871935564, states[0] = 17.097481, states[40]= 0.009743
Saving checkpoint... 
Iteration: 882182551, states[0] = -80.889842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892137411, states[0] = -15.459346, states[40]= 0.001960
Saving checkpoint... 
Iteration: 902420824, states[0] = 22.022419, states[40]= 0.037649
Saving checkpoint... 
Iteration: 912410923, states[0] = 38.153174, states[40]= 0.090770
Saving checkpoint... 
Iteration: 922448298, states[0] = 5.837838, states[40]= 0.006996
Saving checkpoint... 
Iteration: 932449067, states[0] = 4.436410, states[40]= 0.006799
Saving checkpoint... 
Iteration: 942811446, states[0] = -32.964076, states[40]= 0.000381
Saving checkpoint... 
Iteration: 952969997, states[0] = -23.043332, states[40]= 0.000967
Saving checkpoint... 
Iteration: 962789135, states[0] = -5.020237, states[40]= 0.004753
Saving checkpoint... 
Iteration: 972827836, states[0] = -60.482947, states[40]= 0.000008
Saving checkpoint... 
Iteration: 982903529, states[0] = 39.902125, states[40]= 0.075458
Saving checkpoint... 
Iteration: 992726708, states[0] = -87.803629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002818865, states[0] = -51.663022, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1013012024, states[0] = -87.093573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022883451, states[0] = -87.782682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033206482, states[0] = -87.751211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043450915, states[0] = -8.983800, states[40]= 0.003578
Saving checkpoint... 
Iteration: 1053656643, states[0] = -66.148567, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1063429050, states[0] = 9.581628, states[40]= 0.007494
Saving checkpoint... 
Iteration: 1073379856, states[0] = -87.787288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083269335, states[0] = 2.746638, states[40]= 0.006537
Saving checkpoint... 
Iteration: 1093474818, states[0] = -49.313508, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1103599955, states[0] = 3.326734, states[40]= 0.006631
Saving checkpoint... 
Iteration: 1113936662, states[0] = -0.690017, states[40]= 0.005873
Saving checkpoint... 
Iteration: 1124298369, states[0] = -39.960528, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1134505409, states[0] = -87.555806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144646677, states[0] = -64.727632, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1154739611, states[0] = 17.592894, states[40]= 0.010202
Saving checkpoint... 
Iteration: 1164881324, states[0] = -87.817870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175231683, states[0] = 20.172079, states[40]= 0.016805
Saving checkpoint... 
Iteration: 1185097828, states[0] = -2.340529, states[40]= 0.005481
Saving checkpoint... 
Iteration: 1195139333, states[0] = -61.098772, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1205444701, states[0] = -22.976305, states[40]= 0.000972
Saving checkpoint... 
Iteration: 1215828175, states[0] = -87.436762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225663250, states[0] = -87.565136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235566580, states[0] = 16.733029, states[40]= 0.009469
Saving checkpoint... 
Iteration: 1245397257, states[0] = 17.571515, states[40]= 0.010178
Saving checkpoint... 
Iteration: 1255672638, states[0] = -87.703947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265462886, states[0] = -56.934486, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1275275791, states[0] = -29.631561, states[40]= 0.000539
Saving checkpoint... 
Iteration: 1285085733, states[0] = -0.219585, states[40]= 0.005976
Saving checkpoint... 
Iteration: 1294955952, states[0] = -51.145717, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1304874352, states[0] = 27.748151, states[40]= 0.120901
Saving checkpoint... 
Iteration: 1315260951, states[0] = -14.315348, states[40]= 0.002194
Saving checkpoint... 
Iteration: 1325209498, states[0] = 23.182399, states[40]= 0.061667
Saving checkpoint... 
Iteration: 1335332457, states[0] = -87.709035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345499839, states[0] = -87.716645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355442301, states[0] = -40.480515, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1365463020, states[0] = -73.425147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375490908, states[0] = -87.687711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385561635, states[0] = 10.831259, states[40]= 0.007676
Saving checkpoint... 
Iteration: 1395578922, states[0] = -4.713750, states[40]= 0.004841
Saving checkpoint... 
Iteration: 1405684740, states[0] = -87.801161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415822253, states[0] = -87.698600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425864870, states[0] = 24.061843, states[40]= 0.079424
Saving checkpoint... 
Iteration: 1435767561, states[0] = -40.427017, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1446028381, states[0] = 25.240903, states[40]= 0.098440
Saving checkpoint... 
Iteration: 1456191192, states[0] = 31.838741, states[40]= 0.123707
Saving checkpoint... 
Iteration: 1466279635, states[0] = -62.266404, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1476188137, states[0] = 36.749708, states[40]= 0.100633
Saving checkpoint... 
Iteration: 1486340962, states[0] = -87.793998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496351666, states[0] = 41.517446, states[40]= 0.047399
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.698703
 - CaMKt in component CaMK (millimolar): 0.042405
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.000514
 - nass in component intracellular_ions (millimolar): 7.000662
 - ki in component intracellular_ions (millimolar): 144.919802
 - kss in component intracellular_ions (millimolar): 144.919770
 - cansr in component intracellular_ions (millimolar): 1.619809
 - cajsr in component intracellular_ions (millimolar): 1.187705
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007477
 - hf in component INa (dimensionless): 0.691876
 - hs in component INa (dimensionless): 0.691639
 - j in component INa (dimensionless): 0.681138
 - hsp in component INa (dimensionless): 0.446667
 - jp in component INa (dimensionless): 0.654685
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293063
 - hLp in component INaL (dimensionless): 0.136207
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175774
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.212746
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804443
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966933
 - jca in component ICaL (dimensionless): 0.948008
 - ffp in component ICaL (dimensionless): 0.999864
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009461
 - xrf in component IKr (dimensionless): 0.028547
 - xrs in component IKr (dimensionless): 0.786626
 - xs1 in component IKs (dimensionless): 0.458662
 - xs2 in component IKs (dimensionless): 0.001183
 - xk1 in component IK1 (dimensionless): 0.996812
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:55:45 (31392): called boinc_finish(0)

</stderr_txt>
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