𝕏

Task 56163429

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_471_0
Workunit 26673284
Created 4 Jul 2024, 21:15:09 UTC
Sent 5 Jul 2024, 5:44:14 UTC
Report deadline 8 Jul 2024, 5:44:14 UTC
Received 5 Jul 2024, 11:14:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242053
Run time 4 hours 54 min 12 sec
CPU time 4 hours 51 min 39 sec
Validate state Valid
Credit 46.30
Device peak FLOPS 2.31 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_471.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_471_0_r326060667_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_471_0_r326060667_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.418406
     * GNaL_b in INaL: 0.005862
     * Gto_b in Ito: 0.085482
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031840
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.163402
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.487120
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033368
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5356653, states[0] = -94.296158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 10778617, states[0] = -94.314860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15882183, states[0] = -94.276794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21016044, states[0] = -94.246163, states[40]= 0.000000
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Iteration: 25974331, states[0] = -94.228690, states[40]= 0.000000
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Iteration: 31114270, states[0] = -94.209483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36473460, states[0] = -94.189012, states[40]= 0.000000
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Iteration: 41573181, states[0] = -94.179872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46561760, states[0] = -94.175501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51861600, states[0] = -94.167459, states[40]= 0.000000
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Iteration: 56949098, states[0] = -94.164654, states[40]= 0.000000
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Iteration: 62082247, states[0] = -94.162323, states[40]= 0.000000
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Iteration: 67207107, states[0] = -94.160898, states[40]= 0.000000
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Iteration: 72240627, states[0] = -94.160835, states[40]= 0.000000
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Iteration: 82485009, states[0] = -94.160023, states[40]= 0.000000
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Iteration: 87784593, states[0] = -94.158972, states[40]= 0.000000
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Iteration: 93061432, states[0] = -94.158524, states[40]= 0.000000
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Iteration: 98260759, states[0] = -94.158592, states[40]= 0.000000
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Iteration: 108414655, states[0] = -94.159515, states[40]= 0.000000
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Iteration: 123476698, states[0] = -94.161003, states[40]= 0.000000
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Iteration: 128482956, states[0] = -94.161431, states[40]= 0.000000
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Iteration: 133758121, states[0] = -94.161259, states[40]= 0.000000
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Iteration: 138987825, states[0] = -94.161243, states[40]= 0.000000
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Iteration: 144342622, states[0] = -94.161130, states[40]= 0.000000
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Iteration: 149472633, states[0] = -94.161277, states[40]= 0.000000
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Iteration: 154667794, states[0] = -94.161355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160044179, states[0] = 26.426343, states[40]= 0.000000
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Iteration: 165332777, states[0] = -94.041732, states[40]= 0.000000
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Iteration: 170911694, states[0] = -94.199940, states[40]= 0.000000
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Iteration: 176113393, states[0] = -94.192228, states[40]= 0.000000
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Iteration: 181557869, states[0] = -94.179944, states[40]= 0.000000
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Iteration: 186760385, states[0] = -94.176294, states[40]= 0.000000
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Iteration: 197231176, states[0] = -94.170543, states[40]= 0.000000
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Iteration: 202485524, states[0] = -94.168508, states[40]= 0.000000
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Iteration: 207530590, states[0] = -94.168238, states[40]= 0.000000
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Iteration: 212535623, states[0] = -94.168239, states[40]= 0.000000
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Iteration: 217597295, states[0] = -94.167865, states[40]= 0.000000
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Iteration: 222702131, states[0] = -94.167263, states[40]= 0.000000
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Iteration: 227998036, states[0] = -94.165856, states[40]= 0.000000
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Iteration: 233113074, states[0] = -94.165425, states[40]= 0.000000
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Iteration: 238233342, states[0] = -94.165023, states[40]= 0.000000
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Iteration: 243243837, states[0] = -94.164992, states[40]= 0.000000
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Iteration: 248255436, states[0] = -94.164955, states[40]= 0.000000
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Iteration: 253253690, states[0] = -94.164957, states[40]= 0.000000
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Iteration: 258425492, states[0] = -94.164461, states[40]= 0.000000
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Iteration: 263630002, states[0] = -94.163973, states[40]= 0.000000
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Iteration: 268801129, states[0] = -94.163632, states[40]= 0.000000
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Iteration: 273798772, states[0] = -94.163624, states[40]= 0.000000
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Iteration: 279114067, states[0] = -94.163131, states[40]= 0.000000
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Iteration: 284343639, states[0] = -94.162850, states[40]= 0.000000
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Iteration: 289568531, states[0] = -94.162624, states[40]= 0.000000
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Iteration: 294537886, states[0] = -94.162633, states[40]= 0.000000
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Iteration: 314941706, states[0] = -94.162267, states[40]= 0.000000
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Iteration: 325274017, states[0] = -93.878366, states[40]= 0.000000
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Iteration: 330546225, states[0] = -94.197535, states[40]= 0.000000
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Iteration: 335646154, states[0] = -94.206081, states[40]= 0.000000
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Iteration: 340784148, states[0] = -94.205028, states[40]= 0.000000
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Iteration: 350847644, states[0] = -94.202814, states[40]= 0.000000
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Iteration: 355878602, states[0] = -94.201603, states[40]= 0.000000
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Iteration: 366009965, states[0] = -94.196308, states[40]= 0.000000
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Iteration: 371218975, states[0] = -94.188802, states[40]= 0.000000
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Iteration: 376235837, states[0] = -94.188247, states[40]= 0.000000
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Iteration: 381237066, states[0] = -94.188187, states[40]= 0.000000
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Iteration: 386218823, states[0] = -94.188740, states[40]= 0.000000
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Iteration: 391211019, states[0] = -94.188967, states[40]= 0.000000
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Iteration: 396547904, states[0] = -94.180082, states[40]= 0.000000
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Iteration: 401557637, states[0] = -94.179855, states[40]= 0.000000
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Iteration: 406727910, states[0] = -94.176624, states[40]= 0.000000
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Iteration: 411849162, states[0] = -94.174688, states[40]= 0.000000
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Iteration: 417153439, states[0] = -94.170908, states[40]= 0.000000
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Iteration: 422426319, states[0] = -94.168461, states[40]= 0.000000
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Iteration: 427592373, states[0] = -94.167285, states[40]= 0.000000
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Iteration: 432608328, states[0] = -94.167162, states[40]= 0.000000
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Iteration: 437591880, states[0] = -94.167242, states[40]= 0.000000
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Iteration: 442598361, states[0] = -94.167178, states[40]= 0.000000
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Iteration: 447680917, states[0] = -94.166658, states[40]= 0.000000
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Iteration: 452841082, states[0] = -94.165790, states[40]= 0.000000
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Iteration: 457843367, states[0] = -94.165755, states[40]= 0.000000
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Iteration: 462941031, states[0] = -94.165285, states[40]= 0.000000
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Iteration: 467937853, states[0] = -94.165276, states[40]= 0.000000
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Iteration: 472947683, states[0] = -94.165210, states[40]= 0.000000
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Iteration: 477992174, states[0] = -94.165000, states[40]= 0.000000
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Iteration: 483151818, states[0] = -94.164372, states[40]= 0.000000
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Iteration: 488212925, states[0] = -94.164143, states[40]= 0.000000
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Iteration: 493307823, states[0] = -94.163826, states[40]= 0.000000
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Iteration: 498440720, states[0] = -94.163437, states[40]= 0.000000
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Iteration: 503504149, states[0] = -94.163256, states[40]= 0.000000
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Iteration: 508489157, states[0] = -94.163269, states[40]= 0.000000
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Iteration: 513748955, states[0] = -94.162689, states[40]= 0.000000
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Iteration: 518747501, states[0] = -94.162669, states[40]= 0.000000
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Iteration: 529010898, states[0] = -94.162189, states[40]= 0.000000
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Iteration: 534130742, states[0] = -94.162004, states[40]= 0.000000
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Iteration: 539448878, states[0] = -94.161631, states[40]= 0.000000
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Iteration: 544567190, states[0] = -94.161502, states[40]= 0.000000
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Iteration: 549860444, states[0] = -94.161262, states[40]= 0.000000
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Iteration: 555148659, states[0] = -38.540176, states[40]= 0.000299
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Iteration: 560223618, states[0] = -93.613912, states[40]= 0.000000
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Iteration: 565222484, states[0] = -93.606335, states[40]= 0.000000
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Iteration: 570395581, states[0] = -94.127845, states[40]= 0.000000
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Iteration: 575662738, states[0] = -94.205366, states[40]= 0.000000
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Iteration: 585883793, states[0] = -94.200351, states[40]= 0.000000
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Iteration: 590884893, states[0] = -94.200284, states[40]= 0.000000
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Iteration: 596049585, states[0] = -94.193721, states[40]= 0.000000
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Iteration: 601114225, states[0] = -94.191302, states[40]= 0.000000
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Iteration: 616579669, states[0] = -94.178414, states[40]= 0.000000
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Iteration: 621801956, states[0] = -94.174435, states[40]= 0.000000
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Iteration: 626876334, states[0] = -94.173307, states[40]= 0.000000
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Iteration: 642322588, states[0] = -94.168284, states[40]= 0.000000
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Iteration: 662931836, states[0] = -94.164404, states[40]= 0.000000
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Iteration: 683888054, states[0] = -94.161663, states[40]= 0.000000
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Iteration: 710181511, states[0] = -78.938304, states[40]= 0.000002
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Iteration: 720452202, states[0] = -94.166883, states[40]= 0.000000
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Iteration: 725599554, states[0] = -94.201953, states[40]= 0.000000
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Iteration: 730588292, states[0] = -94.200991, states[40]= 0.000000
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Iteration: 740666083, states[0] = -94.204660, states[40]= 0.000000
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Iteration: 854281611, states[0] = -94.160350, states[40]= 0.000000
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Iteration: 911325172, states[0] = -94.183149, states[40]= 0.000000
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Iteration: 956339421, states[0] = -94.182547, states[40]= 0.000000
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Iteration: 961636866, states[0] = -94.175704, states[40]= 0.000000
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Iteration: 971861181, states[0] = -94.171936, states[40]= 0.000000
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Iteration: 997792576, states[0] = -94.163520, states[40]= 0.000000
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Iteration: 1003001669, states[0] = -94.162542, states[40]= 0.000000
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Iteration: 1023948957, states[0] = -94.160000, states[40]= 0.000000
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Iteration: 1029056215, states[0] = -94.159821, states[40]= 0.000000
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Iteration: 1060213194, states[0] = -93.539019, states[40]= 0.000000
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Iteration: 1065478796, states[0] = -94.176858, states[40]= 0.000000
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Iteration: 1070915509, states[0] = -94.196859, states[40]= 0.000000
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Iteration: 1075953800, states[0] = -94.195293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081196162, states[0] = -94.186280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086293934, states[0] = -94.183235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091654729, states[0] = -94.174770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096664732, states[0] = -94.174563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101632286, states[0] = -94.175146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106836537, states[0] = -94.171676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112014548, states[0] = -94.169261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117213693, states[0] = -94.167084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122212562, states[0] = -94.167072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127386920, states[0] = -94.165521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132579673, states[0] = -94.164119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137916067, states[0] = -94.162285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142933202, states[0] = -94.162186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147900653, states[0] = -94.162309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152915760, states[0] = -94.162217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158070893, states[0] = -94.161556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163064371, states[0] = -94.161557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168327531, states[0] = -94.160658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173514507, states[0] = -94.160144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178528402, states[0] = -94.160088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183491598, states[0] = -94.160153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188515074, states[0] = -94.160073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193970139, states[0] = -94.159184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199005994, states[0] = -94.159108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204267421, states[0] = -94.158752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209733982, states[0] = -94.158306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214962403, states[0] = -94.158133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220210547, states[0] = -93.517705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225300419, states[0] = -93.962104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230315273, states[0] = -94.000649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235290384, states[0] = -93.931861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240413704, states[0] = -94.140286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245654837, states[0] = -94.202140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250730333, states[0] = -94.202143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255792561, states[0] = -94.200584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260865989, states[0] = -94.197946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265920548, states[0] = -94.195760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271207712, states[0] = -94.185031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276307223, states[0] = -94.181978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281505788, states[0] = -94.176927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286633699, states[0] = -94.174268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291807448, states[0] = -94.171265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297205448, states[0] = -94.166335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302549914, states[0] = -94.163530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307702882, states[0] = -94.162572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312859200, states[0] = -94.161741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317911484, states[0] = -94.161476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322981939, states[0] = -94.161149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328187133, states[0] = -94.160358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333199572, states[0] = -94.160293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338668987, states[0] = -94.159043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344122887, states[0] = -94.158280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349312398, states[0] = -94.158034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354475241, states[0] = -94.157850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359529690, states[0] = -94.157778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364783742, states[0] = -94.157556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370164962, states[0] = -57.217257, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1375405972, states[0] = -94.133420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380499527, states[0] = -94.182277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385971508, states[0] = -94.193157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391424530, states[0] = -94.178328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396567076, states[0] = -94.175082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401713135, states[0] = -94.172298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406872719, states[0] = -94.169767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411946817, states[0] = -94.168731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417071233, states[0] = -94.167192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422087007, states[0] = -94.166992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427344766, states[0] = -94.164482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432438323, states[0] = -94.163719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437608014, states[0] = -94.162534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443001320, states[0] = -94.160516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448281040, states[0] = -94.159505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453722538, states[0] = -94.158407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459001468, states[0] = -94.157916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464359200, states[0] = -94.157455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469614970, states[0] = -94.157199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474739169, states[0] = -94.157081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479735111, states[0] = -94.157061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484798710, states[0] = -94.156993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489880955, states[0] = -94.156915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494940262, states[0] = -94.156855, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.032784
 - CaMKt in component CaMK (millimolar): 0.000978
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.980117
 - nass in component intracellular_ions (millimolar): 6.980248
 - ki in component intracellular_ions (millimolar): 144.766639
 - kss in component intracellular_ions (millimolar): 144.766628
 - cansr in component intracellular_ions (millimolar): 2.345589
 - cajsr in component intracellular_ions (millimolar): 2.345735
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003950
 - hf in component INa (dimensionless): 0.864083
 - hs in component INa (dimensionless): 0.864083
 - j in component INa (dimensionless): 0.864083
 - hsp in component INa (dimensionless): 0.696543
 - jp in component INa (dimensionless): 0.864083
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.705642
 - hLp in component INaL (dimensionless): 0.511584
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999848
 - iS in component Ito (dimensionless): 0.999848
 - ap in component Ito (dimensionless): 0.000337
 - iFp in component Ito (dimensionless): 0.999848
 - iSp in component Ito (dimensionless): 0.999848
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005125
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002081
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997556
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:13:57 (38879): called boinc_finish(0)

</stderr_txt>
]]>


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