𝕏

Task 56160166

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1
Workunit 26671653
Created 4 Jul 2024, 21:13:40 UTC
Sent 5 Jul 2024, 5:24:36 UTC
Report deadline 8 Jul 2024, 5:24:36 UTC
Received 5 Jul 2024, 15:34:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 163832
Run time 2 hours 14 min 49 sec
CPU time 1 hours 57 min 35 sec
Validate state Valid
Credit 44.62
Device peak FLOPS 2.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1_r1179109444_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1_r1179109444_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.793206
     * GNaL_b in INaL: 0.005745
     * Gto_b in Ito: 0.084510
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031842
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.163592
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.582858
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032439
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12597575, states[0] = -94.084236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25158155, states[0] = -94.014313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35536044, states[0] = -93.979188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46722619, states[0] = -93.991819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55894529, states[0] = -93.956452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68727560, states[0] = -93.985799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81488800, states[0] = -93.961696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94268446, states[0] = -93.557993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106873635, states[0] = -93.982502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119596976, states[0] = -93.957809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132293366, states[0] = -93.651117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144976020, states[0] = -93.978471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157758319, states[0] = -93.953865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170503765, states[0] = -93.946629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183298459, states[0] = -93.965991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195951224, states[0] = -93.950149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208434147, states[0] = -93.903872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221030570, states[0] = -93.975979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233692230, states[0] = -93.954962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246470640, states[0] = -93.929571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259269008, states[0] = -93.966766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270163172, states[0] = -41.812432, states[40]= 0.000705
Saving checkpoint... 
Iteration: 279029286, states[0] = -93.975872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291802427, states[0] = -93.952537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304317436, states[0] = -93.721963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316992198, states[0] = -93.977244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329270153, states[0] = -93.966550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341241249, states[0] = -93.967544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352762075, states[0] = -93.983154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363925914, states[0] = -93.950121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374689521, states[0] = -93.981442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386123796, states[0] = -11.380750, states[40]= 0.002256
Saving checkpoint... 
Iteration: 397544133, states[0] = -93.958083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409251518, states[0] = -93.967013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420531005, states[0] = -93.956242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429112377, states[0] = -93.972200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440390768, states[0] = -93.858245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451605667, states[0] = -93.956412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460546087, states[0] = -93.960769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469451325, states[0] = -93.960445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480625213, states[0] = -93.975987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491830329, states[0] = -93.951518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502710979, states[0] = -93.981981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513603080, states[0] = -93.956325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524363193, states[0] = -93.817854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535163658, states[0] = -93.969953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543107547, states[0] = -93.972115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552303084, states[0] = -93.680771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561812490, states[0] = -93.951687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571380650, states[0] = -93.962316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580899986, states[0] = -93.979985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590099307, states[0] = 4.748535, states[40]= 0.003226
Saving checkpoint... 
Iteration: 600055756, states[0] = 22.681229, states[40]= 0.000475
Saving checkpoint... 
Iteration: 609589212, states[0] = -93.956432, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1_r1179109444_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1_r1179109444_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.793206
     * GNaL_b in INaL: 0.005745
     * Gto_b in Ito: 0.084510
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031842
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.163592
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.582858
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032439
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 609589212
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.956432 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 621869038, states[0] = -93.950491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634102520, states[0] = 3.072861, states[40]= 0.003440
Saving checkpoint... 
Iteration: 645754207, states[0] = -93.952638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654758003, states[0] = -93.982412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667440580, states[0] = -93.960278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680203732, states[0] = -77.913377, states[40]= 0.000003
Saving checkpoint... 
Iteration: 692952081, states[0] = -93.977874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705542556, states[0] = -93.957379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718201248, states[0] = -74.799806, states[40]= 0.000004
Saving checkpoint... 
Iteration: 730907679, states[0] = -93.979367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743511741, states[0] = -93.958102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756186326, states[0] = -60.304821, states[40]= 0.000046
Saving checkpoint... 
Iteration: 768816349, states[0] = -93.981710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781386633, states[0] = -93.961623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791164467, states[0] = -93.969304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800351770, states[0] = -93.797066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812964817, states[0] = -93.977104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825641689, states[0] = -93.954655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838422362, states[0] = -93.891870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851182186, states[0] = -93.968487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863822852, states[0] = -93.950760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876279754, states[0] = -93.600374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888864086, states[0] = -93.980334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901590435, states[0] = -93.955696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914118785, states[0] = -7.385450, states[40]= 0.002965
Saving checkpoint... 
Iteration: 926829584, states[0] = -93.981080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939527598, states[0] = -93.957206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952317086, states[0] = -93.719452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965092156, states[0] = -93.971706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977561149, states[0] = -93.956245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989993698, states[0] = -93.947499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002676661, states[0] = -93.979238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015212230, states[0] = -93.966971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027770897, states[0] = -93.951377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040286968, states[0] = -93.626528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052916148, states[0] = -93.978302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063255281, states[0] = -93.965300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071698713, states[0] = -93.952779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084379678, states[0] = -93.841808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095286388, states[0] = -93.964137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104486127, states[0] = -93.936004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116757398, states[0] = -93.981297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129441178, states[0] = -93.959145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138326615, states[0] = -93.742965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151073534, states[0] = -93.971998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163825666, states[0] = -93.949981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176541701, states[0] = -93.957769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189293600, states[0] = -93.963664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201897397, states[0] = -93.948585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214108021, states[0] = -0.038684, states[40]= 0.003644
Saving checkpoint... 
Iteration: 1226049858, states[0] = 24.692396, states[40]= 0.000339
Saving checkpoint... 
Iteration: 1238197581, states[0] = -70.653941, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1250230512, states[0] = -93.331043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262295988, states[0] = -93.656704, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1_r1179109444_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_4000-conf_368_1_r1179109444_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.793206
     * GNaL_b in INaL: 0.005745
     * Gto_b in Ito: 0.084510
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031842
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.163592
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.582858
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032439
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1262295988
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.656704 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1272242084, states[0] = -93.430933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283367029, states[0] = -93.961023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295909805, states[0] = -93.948143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308567521, states[0] = -93.964196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321284016, states[0] = -93.963673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333774819, states[0] = -93.950559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346238107, states[0] = -93.407510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355516353, states[0] = -93.956500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368154805, states[0] = -35.391135, states[40]= 0.001461
Saving checkpoint... 
Iteration: 1380668491, states[0] = -93.977809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388578728, states[0] = -93.966417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399611711, states[0] = -93.953976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412125357, states[0] = -12.661159, states[40]= 0.002058
Saving checkpoint... 
Iteration: 1424706352, states[0] = -93.979607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437289253, states[0] = -93.963213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449569475, states[0] = -93.954894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461569562, states[0] = -93.954862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473567770, states[0] = -93.954879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485568449, states[0] = -93.954832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497578712, states[0] = -93.954546, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.822135
 - CaMKt in component CaMK (millimolar): 0.002078
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.723765
 - nass in component intracellular_ions (millimolar): 6.723888
 - ki in component intracellular_ions (millimolar): 145.134820
 - kss in component intracellular_ions (millimolar): 145.134809
 - cansr in component intracellular_ions (millimolar): 1.831894
 - cajsr in component intracellular_ions (millimolar): 1.831743
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004035
 - hf in component INa (dimensionless): 0.859967
 - hs in component INa (dimensionless): 0.859967
 - j in component INa (dimensionless): 0.859971
 - hsp in component INa (dimensionless): 0.689182
 - jp in component INa (dimensionless): 0.859973
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699814
 - hLp in component INaL (dimensionless): 0.504082
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.991407
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.996553
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996446
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005256
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008113
 - xs1 in component IKs (dimensionless): 0.041475
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997607
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:38:34 (5220): called boinc_finish(0)

</stderr_txt>
]]>


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