𝕏

Task 56157362

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1
Workunit 26670256
Created 4 Jul 2024, 21:12:16 UTC
Sent 5 Jul 2024, 5:13:16 UTC
Report deadline 8 Jul 2024, 5:13:16 UTC
Received 5 Jul 2024, 21:23:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 2 hours 12 min 28 sec
CPU time 1 hours 35 min 15 sec
Validate state Valid
Credit 45.65
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.39 MB
Peak swap size 4.37 GB
Peak disk usage 1.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1_r297190380_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1_r297190380_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.221407
     * GNaL_b in INaL: 0.005865
     * Gto_b in Ito: 0.083724
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031814
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162745
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.245101
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032028
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11963577, states[0] = -86.735991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24337432, states[0] = -86.585911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37011462, states[0] = -86.611332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49419775, states[0] = -86.570617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61940410, states[0] = -86.541779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74336511, states[0] = -86.457473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87128527, states[0] = -86.522852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99974132, states[0] = -86.504017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112923977, states[0] = -86.511768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125917571, states[0] = -86.493464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139013470, states[0] = -86.502280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150752709, states[0] = -86.503491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164438192, states[0] = -86.471392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176577489, states[0] = -86.494584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189354563, states[0] = -86.489837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202450472, states[0] = -86.472179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215374241, states[0] = -86.488293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229728951, states[0] = -86.483636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244323084, states[0] = -86.403919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259400510, states[0] = -86.486961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274069665, states[0] = 10.510799, states[40]= 0.004224
Saving checkpoint... 
Iteration: 288561855, states[0] = -86.489853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301898053, states[0] = -86.481394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316266842, states[0] = -86.338030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330726476, states[0] = -86.496791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345130548, states[0] = -86.491115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359805352, states[0] = -86.481965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374330711, states[0] = -86.409818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388872448, states[0] = -86.495881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403946049, states[0] = -86.480869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419108336, states[0] = -86.491478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434406813, states[0] = -86.455348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449623229, states[0] = -86.483627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464755552, states[0] = -86.496800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479726071, states[0] = -86.482593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494780927, states[0] = -86.496752, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1_r297190380_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1_r297190380_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.221407
     * GNaL_b in INaL: 0.005865
     * Gto_b in Ito: 0.083724
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031814
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162745
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.245101
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032028
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 494780927
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.496752 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1_r297190380_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_4000-conf_65_1_r297190380_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.221407
     * GNaL_b in INaL: 0.005865
     * Gto_b in Ito: 0.083724
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031814
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.162745
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.245101
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032028
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 494780927
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.496752 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 507364409, states[0] = -86.486950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519316363, states[0] = -86.487702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531565289, states[0] = -86.484254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544504278, states[0] = -86.482031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556938748, states[0] = -86.494730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568665791, states[0] = -86.495610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580252315, states[0] = -86.315917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591559590, states[0] = -86.484308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602681345, states[0] = -86.495995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613391100, states[0] = -86.486528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624268894, states[0] = -86.340790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634352285, states[0] = -86.426049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644521274, states[0] = -86.484678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656391788, states[0] = -86.448640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668551329, states[0] = -86.488453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679813683, states[0] = -86.481788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690963931, states[0] = -86.494239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702666655, states[0] = -86.495608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714027954, states[0] = 21.069158, states[40]= 0.005215
Saving checkpoint... 
Iteration: 724819552, states[0] = -86.496441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735207187, states[0] = -86.489537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745310048, states[0] = -86.487760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755909442, states[0] = -86.481041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766351296, states[0] = -86.425345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776367743, states[0] = -86.435855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787339739, states[0] = -86.487277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798400404, states[0] = -86.452542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809808409, states[0] = -86.481807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821134811, states[0] = -86.490877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831551590, states[0] = -86.484357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841812379, states[0] = -86.481768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853332760, states[0] = -86.487374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865252529, states[0] = -86.488706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876721367, states[0] = -86.496554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887308974, states[0] = -86.487750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897855986, states[0] = -86.481410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909071179, states[0] = -86.492102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920401964, states[0] = -86.453198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932344393, states[0] = -86.420400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944050613, states[0] = 16.067008, states[40]= 0.004202
Saving checkpoint... 
Iteration: 955498225, states[0] = -86.484990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966199019, states[0] = -85.843660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976686944, states[0] = -86.496041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987222891, states[0] = -86.489205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997096712, states[0] = -86.491583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006890081, states[0] = -86.495472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016433555, states[0] = -86.465041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026128373, states[0] = -23.514210, states[40]= 0.000801
Saving checkpoint... 
Iteration: 1035317323, states[0] = -86.487586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044734850, states[0] = -86.496620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053843811, states[0] = -86.481475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063422547, states[0] = -86.485987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073013405, states[0] = -86.493211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082582551, states[0] = -86.491277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092911792, states[0] = -86.495100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103011736, states[0] = -86.493238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112806787, states[0] = -86.496478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122172509, states[0] = -62.843263, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1132491813, states[0] = -86.479675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143783592, states[0] = -86.481951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155615878, states[0] = -86.483565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167238374, states[0] = -86.488896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179186262, states[0] = -86.489836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190503009, states[0] = -86.481690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201136750, states[0] = -86.490767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211902393, states[0] = -86.481004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222058917, states[0] = 13.792100, states[40]= 0.004226
Saving checkpoint... 
Iteration: 1230856749, states[0] = -86.495916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241503292, states[0] = -86.484870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252621583, states[0] = -86.493752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264012382, states[0] = 21.998588, states[40]= 0.025824
Saving checkpoint... 
Iteration: 1273706300, states[0] = -86.482623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283599793, states[0] = -86.483717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294132124, states[0] = -26.621553, states[40]= 0.000678
Saving checkpoint... 
Iteration: 1304949799, states[0] = -86.494384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315096293, states[0] = -86.491530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325457741, states[0] = -86.485450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336647127, states[0] = -86.494854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347067786, states[0] = -86.492085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357456668, states[0] = -86.485459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368514934, states[0] = -86.483594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378609262, states[0] = -86.493051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389899269, states[0] = -86.480992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400345078, states[0] = -86.420811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410595368, states[0] = -86.492159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421790121, states[0] = -86.481842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431772904, states[0] = -86.481987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441775752, states[0] = -86.481961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451689214, states[0] = -86.482754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461917733, states[0] = -86.480846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471809084, states[0] = -86.481674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482721158, states[0] = -86.496436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493358095, states[0] = -86.486856, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.356258
 - CaMKt in component CaMK (millimolar): 0.000893
 - cass in component intracellular_ions (millimolar): 0.000070
 - nai in component intracellular_ions (millimolar): 6.054733
 - nass in component intracellular_ions (millimolar): 6.054778
 - ki in component intracellular_ions (millimolar): 145.940850
 - kss in component intracellular_ions (millimolar): 145.940840
 - cansr in component intracellular_ions (millimolar): 1.251458
 - cajsr in component intracellular_ions (millimolar): 1.251595
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008558
 - hf in component INa (dimensionless): 0.642971
 - hs in component INa (dimensionless): 0.642972
 - j in component INa (dimensionless): 0.642975
 - hsp in component INa (dimensionless): 0.394021
 - jp in component INa (dimensionless): 0.642976
 - mL in component INaL (dimensionless): 0.000251
 - hL in component INaL (dimensionless): 0.462378
 - hLp in component INaL (dimensionless): 0.272883
 - a in component Ito (dimensionless): 0.001109
 - iF in component Ito (dimensionless): 0.999418
 - iS in component Ito (dimensionless): 0.985463
 - ap in component Ito (dimensionless): 0.000565
 - iFp in component Ito (dimensionless): 0.999418
 - iSp in component Ito (dimensionless): 0.991580
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997466
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001272
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020599
 - xs1 in component IKs (dimensionless): 0.037461
 - xs2 in component IKs (dimensionless): 0.000229
 - xk1 in component IK1 (dimensionless): 0.997136
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:02:40 (10555): called boinc_finish(0)

</stderr_txt>
]]>


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