𝕏

Task 56156336

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1
Workunit 26669759
Created 4 Jul 2024, 21:11:50 UTC
Sent 5 Jul 2024, 5:11:04 UTC
Report deadline 8 Jul 2024, 5:11:04 UTC
Received 5 Jul 2024, 21:23:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 2 hours 13 min 13 sec
CPU time 1 hours 36 min 36 sec
Validate state Valid
Credit 45.62
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.93 MB
Peak swap size 4.38 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1_r1881478677_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1_r1881478677_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.082790
     * GNaL_b in INaL: 0.005879
     * Gto_b in Ito: 0.083864
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031875
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.162547
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.352639
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033009
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12423683, states[0] = -84.547675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25052636, states[0] = 18.686124, states[40]= 0.000042
Saving checkpoint... 
Iteration: 37528955, states[0] = 28.590522, states[40]= 0.000079
Saving checkpoint... 
Iteration: 49975685, states[0] = -84.501545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62231522, states[0] = -84.014213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74275684, states[0] = -84.209114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86510098, states[0] = 30.792247, states[40]= 0.056535
Saving checkpoint... 
Iteration: 99038084, states[0] = 25.363283, states[40]= 0.000016
Saving checkpoint... 
Iteration: 111479265, states[0] = -84.485851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123831310, states[0] = -84.345797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136390675, states[0] = -84.427229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148867104, states[0] = -84.400086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 161587129, states[0] = 1.387074, states[40]= 0.000380
Saving checkpoint... 
Iteration: 174377820, states[0] = -84.412157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187310269, states[0] = -84.298769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200247540, states[0] = -84.082594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212651654, states[0] = -61.045158, states[40]= 0.000007
Saving checkpoint... 
Iteration: 225267928, states[0] = -84.169573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237714384, states[0] = -83.892461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250131245, states[0] = -40.066470, states[40]= 0.000108
Saving checkpoint... 
Iteration: 264016580, states[0] = 31.560947, states[40]= 0.005721
Saving checkpoint... 
Iteration: 276159176, states[0] = -69.910230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 290047118, states[0] = 21.588009, states[40]= 0.000026
Saving checkpoint... 
Iteration: 304520481, states[0] = 31.079480, states[40]= 0.001449
Saving checkpoint... 
Iteration: 319484784, states[0] = -84.482326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334377582, states[0] = -84.409393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348517716, states[0] = 31.476149, states[40]= 0.003833
Saving checkpoint... 
Iteration: 361809650, states[0] = -84.294731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376044524, states[0] = 22.714329, states[40]= 0.000022
Saving checkpoint... 
Iteration: 390437882, states[0] = -84.459381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404801698, states[0] = -84.274317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419352130, states[0] = -84.374943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 433813982, states[0] = -84.303887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448182114, states[0] = -83.499352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462936262, states[0] = -84.457465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477943670, states[0] = -84.461616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492897893, states[0] = -84.428153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508001785, states[0] = 36.160793, states[40]= 0.940967
Saving checkpoint... 
Iteration: 523059996, states[0] = 15.706424, states[40]= 0.000070
Saving checkpoint... 
Iteration: 538053878, states[0] = 18.558876, states[40]= 0.000044
Saving checkpoint... 
Iteration: 552947674, states[0] = -84.462857, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1_r1881478677_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1_r1881478677_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.082790
     * GNaL_b in INaL: 0.005879
     * Gto_b in Ito: 0.083864
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031875
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.162547
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.352639
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033009
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 552947674
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.462857 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1_r1881478677_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_1000-conf_864_1_r1881478677_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.082790
     * GNaL_b in INaL: 0.005879
     * Gto_b in Ito: 0.083864
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031875
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.162547
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.352639
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033009
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 552947674
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.462857 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 565347675, states[0] = -84.366212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577156491, states[0] = -66.622663, states[40]= 0.000003
Saving checkpoint... 
Iteration: 589192008, states[0] = -83.714809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601960325, states[0] = -84.468605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614188527, states[0] = -83.670035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625714520, states[0] = -83.888102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637146340, states[0] = -55.303591, states[40]= 0.000015
Saving checkpoint... 
Iteration: 648331359, states[0] = -84.337064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659288847, states[0] = -84.234913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669891678, states[0] = -84.419965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680608537, states[0] = -17.182046, states[40]= 0.000291
Saving checkpoint... 
Iteration: 690511059, states[0] = 31.078254, states[40]= 0.040210
Saving checkpoint... 
Iteration: 700502550, states[0] = 34.218085, states[40]= 0.780937
Saving checkpoint... 
Iteration: 712116228, states[0] = -25.110777, states[40]= 0.000263
Saving checkpoint... 
Iteration: 724213792, states[0] = -83.881920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735255248, states[0] = -84.110726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746256629, states[0] = -84.116613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757723693, states[0] = -83.945011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768979822, states[0] = -84.474703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 779607425, states[0] = -16.011014, states[40]= 0.000309
Saving checkpoint... 
Iteration: 789831990, states[0] = -84.336405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799784258, states[0] = -84.218869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810283382, states[0] = -84.215935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820559837, states[0] = 15.783481, states[40]= 0.000069
Saving checkpoint... 
Iteration: 830439531, states[0] = -84.454685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841233745, states[0] = -84.002621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852147648, states[0] = -56.673689, states[40]= 0.000013
Saving checkpoint... 
Iteration: 863392399, states[0] = -84.418168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874537911, states[0] = 25.470448, states[40]= 0.000016
Saving checkpoint... 
Iteration: 884807711, states[0] = -84.283224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894923865, states[0] = -84.443801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906270676, states[0] = -84.170848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918037038, states[0] = 25.818980, states[40]= 0.000016
Saving checkpoint... 
Iteration: 929376063, states[0] = -84.399941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939796196, states[0] = -84.252510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950141195, states[0] = -50.003963, states[40]= 0.000032
Saving checkpoint... 
Iteration: 961199580, states[0] = -83.777011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972434850, states[0] = -84.450024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984196944, states[0] = -83.755484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995706707, states[0] = -83.829359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007022436, states[0] = 30.673893, states[40]= 0.000730
Saving checkpoint... 
Iteration: 1017554937, states[0] = 18.074963, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1027894678, states[0] = -84.418233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038264547, states[0] = -84.145612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048013126, states[0] = 31.458769, states[40]= 0.019366
Saving checkpoint... 
Iteration: 1057683082, states[0] = -83.530922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067067660, states[0] = 11.990606, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1076610333, states[0] = -19.055746, states[40]= 0.000272
Saving checkpoint... 
Iteration: 1085670130, states[0] = -80.889185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094991440, states[0] = -84.474628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103943855, states[0] = -84.453646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113379219, states[0] = -84.401156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122840207, states[0] = -84.346738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132306575, states[0] = -84.277201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142516734, states[0] = 31.556523, states[40]= 0.005417
Saving checkpoint... 
Iteration: 1152464926, states[0] = -84.463619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162147291, states[0] = -56.287426, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1171394376, states[0] = -84.416089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181540471, states[0] = 24.428392, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1192674756, states[0] = -82.642186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204268780, states[0] = -84.159828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215684482, states[0] = -83.575601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227478021, states[0] = -84.468106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238659808, states[0] = -70.643934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1249125724, states[0] = -34.578249, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1259755248, states[0] = -84.103794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269770237, states[0] = -84.164434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278447838, states[0] = -84.453589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288927224, states[0] = -84.441014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299875113, states[0] = -84.394037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311163082, states[0] = -74.592139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320686437, states[0] = -83.622603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330463266, states[0] = -84.460575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340910645, states[0] = -84.428147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351556307, states[0] = 17.442941, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1361528252, states[0] = 29.029558, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1371683604, states[0] = -83.545266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382758242, states[0] = -84.115137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393025512, states[0] = 29.871588, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1403223791, states[0] = -83.936987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414128287, states[0] = -37.112041, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1424083558, states[0] = 3.561327, states[40]= 0.000318
Saving checkpoint... 
Iteration: 1435187763, states[0] = -83.646131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445503155, states[0] = 32.670635, states[40]= 0.638413
Saving checkpoint... 
Iteration: 1455571254, states[0] = 10.188890, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1466569255, states[0] = 11.197712, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1476452886, states[0] = -84.453684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486314264, states[0] = -84.290802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496074909, states[0] = 8.305563, states[40]= 0.000192
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.347994
 - CaMKt in component CaMK (millimolar): 0.016703
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.600950
 - nass in component intracellular_ions (millimolar): 6.601069
 - ki in component intracellular_ions (millimolar): 145.185979
 - kss in component intracellular_ions (millimolar): 145.185955
 - cansr in component intracellular_ions (millimolar): 1.793971
 - cajsr in component intracellular_ions (millimolar): 1.739503
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.010468
 - hf in component INa (dimensionless): 0.564222
 - hs in component INa (dimensionless): 0.564189
 - j in component INa (dimensionless): 0.564016
 - hsp in component INa (dimensionless): 0.318462
 - jp in component INa (dimensionless): 0.563893
 - mL in component INaL (dimensionless): 0.000368
 - hL in component INaL (dimensionless): 0.382900
 - hLp in component INaL (dimensionless): 0.181635
 - a in component Ito (dimensionless): 0.001270
 - iF in component Ito (dimensionless): 0.999173
 - iS in component Ito (dimensionless): 0.549341
 - ap in component Ito (dimensionless): 0.000647
 - iFp in component Ito (dimensionless): 0.999173
 - iSp in component Ito (dimensionless): 0.589543
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.907955
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999802
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003518
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.507719
 - xs1 in component IKs (dimensionless): 0.281613
 - xs2 in component IKs (dimensionless): 0.000286
 - xk1 in component IK1 (dimensionless): 0.996836
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
14:58:18 (10554): called boinc_finish(0)

</stderr_txt>
]]>


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