𝕏

Task 56151513

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_960_0
Workunit 26667350
Created 4 Jul 2024, 21:09:34 UTC
Sent 5 Jul 2024, 4:28:59 UTC
Report deadline 8 Jul 2024, 4:28:59 UTC
Received 5 Jul 2024, 9:05:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 2 hours 1 min 49 sec
CPU time 1 hours 39 min 10 sec
Validate state Valid
Credit 44.37
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.94 MB
Peak swap size 4.51 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_960.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_960_0_r397209329_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_960_0_r397209329_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.900680
     * GNaL_b in INaL: 0.005887
     * Gto_b in Ito: 0.085253
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031772
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.163853
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.157879
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033357
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12324590, states[0] = -94.908708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24523792, states[0] = 26.103469, states[40]= 0.001900
Saving checkpoint... 
Iteration: 36750425, states[0] = -94.716203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48968364, states[0] = -94.936765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61107862, states[0] = -20.052142, states[40]= 0.001290
Saving checkpoint... 
Iteration: 73094788, states[0] = -7.363930, states[40]= 0.003257
Saving checkpoint... 
Iteration: 84970601, states[0] = -94.932431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97359869, states[0] = -94.876311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109838139, states[0] = -94.855479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122253794, states[0] = -94.711786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134469484, states[0] = -94.930293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146337185, states[0] = -94.853666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158410726, states[0] = -94.907948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170428157, states[0] = -94.915776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182728164, states[0] = -94.633990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194969639, states[0] = -94.929689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207086375, states[0] = -0.590288, states[40]= 0.004459
Saving checkpoint... 
Iteration: 219415256, states[0] = -94.909706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231487083, states[0] = -94.933832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243798535, states[0] = -94.802549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255686136, states[0] = -94.424318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267285147, states[0] = -94.779496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279517605, states[0] = 27.376006, states[40]= 0.004711
Saving checkpoint... 
Iteration: 291751923, states[0] = -94.705487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303880418, states[0] = -94.889486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316221792, states[0] = -94.610728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328703391, states[0] = -94.537058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341268629, states[0] = -94.745821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353914034, states[0] = -94.908542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366675086, states[0] = -93.409957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380536410, states[0] = 22.548709, states[40]= 0.001834
Saving checkpoint... 
Iteration: 393181484, states[0] = -94.291083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405518947, states[0] = 27.204442, states[40]= 0.003422
Saving checkpoint... 
Iteration: 417988982, states[0] = -94.933480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430381217, states[0] = -94.889511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442864599, states[0] = -94.877314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455215183, states[0] = -94.585157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466888379, states[0] = -94.893997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479018566, states[0] = 27.257323, states[40]= 0.003729
Saving checkpoint... 
Iteration: 491673653, states[0] = -92.893170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503922957, states[0] = -94.912040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516041246, states[0] = 20.834771, states[40]= 0.002118
Saving checkpoint... 
Iteration: 528111622, states[0] = -23.466576, states[40]= 0.001217
Saving checkpoint... 
Iteration: 540646927, states[0] = -58.854213, states[40]= 0.000023
Saving checkpoint... 
Iteration: 553219347, states[0] = -94.600694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565944138, states[0] = -94.920165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578572091, states[0] = 7.821510, states[40]= 0.004396
Saving checkpoint... 
Iteration: 591196448, states[0] = -94.504068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603830075, states[0] = -94.843686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616346500, states[0] = -94.860799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628773716, states[0] = -94.755583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641122454, states[0] = -33.769907, states[40]= 0.000738
Saving checkpoint... 
Iteration: 653436092, states[0] = -94.916842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665805497, states[0] = -94.811501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678367353, states[0] = -94.878521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690784565, states[0] = -94.776694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702959076, states[0] = -94.924521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715207858, states[0] = -94.554516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727356453, states[0] = -94.869411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739595351, states[0] = -7.748842, states[40]= 0.003172
Saving checkpoint... 
Iteration: 751907619, states[0] = -94.903749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764114341, states[0] = -26.056435, states[40]= 0.001169
Saving checkpoint... 
Iteration: 776113460, states[0] = -25.218798, states[40]= 0.001189
Saving checkpoint... 
Iteration: 787905254, states[0] = -94.902375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800498037, states[0] = -94.933857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813256446, states[0] = -94.715086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825289406, states[0] = -94.784891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836890878, states[0] = -94.894043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849419748, states[0] = -94.909214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862055948, states[0] = 15.149820, states[40]= 0.003231
Saving checkpoint... 
Iteration: 874610236, states[0] = -22.135882, states[40]= 0.001237
Saving checkpoint... 
Iteration: 887073226, states[0] = 7.239397, states[40]= 0.004452
Saving checkpoint... 
Iteration: 899637412, states[0] = -48.673498, states[40]= 0.000113
Saving checkpoint... 
Iteration: 912244563, states[0] = -94.682583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924704758, states[0] = -94.540531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937226289, states[0] = -94.624294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949755672, states[0] = -94.712565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962277468, states[0] = -94.761907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974621536, states[0] = -32.891758, states[40]= 0.000800
Saving checkpoint... 
Iteration: 987612447, states[0] = -24.252991, states[40]= 0.001206
Saving checkpoint... 
Iteration: 1000164990, states[0] = -83.547253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012729420, states[0] = -94.634771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025348351, states[0] = -94.860904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037979903, states[0] = -94.928866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050512677, states[0] = 27.655044, states[40]= 0.020330
Saving checkpoint... 
Iteration: 1063018864, states[0] = 27.217037, states[40]= 0.003486
Saving checkpoint... 
Iteration: 1075529585, states[0] = 24.752322, states[40]= 0.001561
Saving checkpoint... 
Iteration: 1087893677, states[0] = -94.894709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100384094, states[0] = -94.888710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112216164, states[0] = -94.586281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124686931, states[0] = -94.431958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137171387, states[0] = -91.579528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149441551, states[0] = -94.916886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161950818, states[0] = -94.920053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174319911, states[0] = -94.829175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187066708, states[0] = 10.445079, states[40]= 0.004068
Saving checkpoint... 
Iteration: 1199824856, states[0] = -94.835174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212705415, states[0] = -94.542165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225727792, states[0] = -94.628337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238639950, states[0] = -51.340280, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1250471481, states[0] = -94.925856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263334649, states[0] = -94.846100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275412169, states[0] = -94.903921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289032248, states[0] = 23.931767, states[40]= 0.001643
Saving checkpoint... 
Iteration: 1301712970, states[0] = -94.572965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314934670, states[0] = -94.913626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329204125, states[0] = -94.536143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343801110, states[0] = -94.802119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358780436, states[0] = -94.766152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373120485, states[0] = -31.888571, states[40]= 0.000869
Saving checkpoint... 
Iteration: 1387563852, states[0] = 11.754835, states[40]= 0.003862
Saving checkpoint... 
Iteration: 1400662216, states[0] = -78.945708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414978457, states[0] = -94.926991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429274870, states[0] = -94.754729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443499904, states[0] = -94.931641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458020332, states[0] = 26.988523, states[40]= 0.002603
Saving checkpoint... 
Iteration: 1472501059, states[0] = 47.255998, states[40]= 0.183667
Saving checkpoint... 
Iteration: 1487015691, states[0] = 27.550948, states[40]= 0.007981
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.807309
 - CaMKt in component CaMK (millimolar): 0.012812
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.745185
 - nass in component intracellular_ions (millimolar): 6.745283
 - ki in component intracellular_ions (millimolar): 145.133917
 - kss in component intracellular_ions (millimolar): 145.133895
 - cansr in component intracellular_ions (millimolar): 1.673787
 - cajsr in component intracellular_ions (millimolar): 1.632089
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003653
 - hf in component INa (dimensionless): 0.878351
 - hs in component INa (dimensionless): 0.878343
 - j in component INa (dimensionless): 0.878292
 - hsp in component INa (dimensionless): 0.722708
 - jp in component INa (dimensionless): 0.878257
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.704802
 - hLp in component INaL (dimensionless): 0.441966
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.611420
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.682314
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916060
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999834
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003097
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.365363
 - xs1 in component IKs (dimensionless): 0.267516
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997362
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:59:26 (40580): called boinc_finish(0)

</stderr_txt>
]]>


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