𝕏

Task 56150821

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_2000-conf_659_1
Workunit 26667007
Created 4 Jul 2024, 21:09:13 UTC
Sent 5 Jul 2024, 4:26:46 UTC
Report deadline 8 Jul 2024, 4:26:46 UTC
Received 5 Jul 2024, 9:05:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 2 hours 2 min 41 sec
CPU time 1 hours 39 min 23 sec
Validate state Valid
Credit 44.77
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 4.26 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_2000-conf_659.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_2000-conf_659_1_r838898415_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_2000-conf_659_1_r838898415_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.901475
     * GNaL_b in INaL: 0.005820
     * Gto_b in Ito: 0.085232
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031976
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163961
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.618961
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032371
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11671041, states[0] = -94.300485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22549584, states[0] = -94.267368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34723782, states[0] = -94.312959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47025184, states[0] = 34.342345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59542192, states[0] = -94.312418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71822275, states[0] = -94.352202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84127609, states[0] = 2.159986, states[40]= 0.000551
Saving checkpoint... 
Iteration: 96476349, states[0] = -94.299639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108756464, states[0] = -94.370685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120867777, states[0] = -94.370073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132725855, states[0] = -94.374981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144933021, states[0] = -94.369625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157268287, states[0] = -93.678330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169583163, states[0] = -94.362044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182054380, states[0] = 29.767993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193926280, states[0] = -94.371197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206051971, states[0] = 30.411531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218087071, states[0] = 18.258438, states[40]= 0.000017
Saving checkpoint... 
Iteration: 230165394, states[0] = -20.733976, states[40]= 0.004057
Saving checkpoint... 
Iteration: 242538802, states[0] = -94.347022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254763724, states[0] = -94.376149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266858542, states[0] = -94.372909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279185635, states[0] = -29.898235, states[40]= 0.007714
Saving checkpoint... 
Iteration: 291320070, states[0] = -93.991975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303640814, states[0] = -94.369426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315261024, states[0] = -93.470868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327211585, states[0] = -45.919292, states[40]= 0.001715
Saving checkpoint... 
Iteration: 339302950, states[0] = -93.909520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351469758, states[0] = -94.302022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363595529, states[0] = -94.360022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 375699089, states[0] = -94.371241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388429442, states[0] = -94.258442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400913047, states[0] = -94.365549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413685443, states[0] = -94.369266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426440078, states[0] = -94.270055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440479228, states[0] = -94.306490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452910908, states[0] = -94.363839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465221709, states[0] = -53.726410, states[40]= 0.000611
Saving checkpoint... 
Iteration: 477738729, states[0] = -94.368489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490028088, states[0] = 33.871058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502759184, states[0] = -94.367572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514565377, states[0] = -94.346981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526704969, states[0] = -94.366113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538972112, states[0] = -94.357329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551596071, states[0] = -94.353478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564007827, states[0] = 27.899299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575641229, states[0] = -94.359864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588100564, states[0] = 12.780800, states[40]= 0.000070
Saving checkpoint... 
Iteration: 600558244, states[0] = -94.341676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 613211858, states[0] = -46.106840, states[40]= 0.001674
Saving checkpoint... 
Iteration: 626042271, states[0] = 32.564385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638792679, states[0] = -94.362189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651542631, states[0] = -94.334271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664219404, states[0] = -51.884575, states[40]= 0.000788
Saving checkpoint... 
Iteration: 676894586, states[0] = -94.356737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689057105, states[0] = 28.962866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701161260, states[0] = -18.612856, states[40]= 0.002626
Saving checkpoint... 
Iteration: 713458834, states[0] = -94.279388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 726016075, states[0] = 32.379879, states[40]= -0.000000
Saving checkpoint... 
Iteration: 738594311, states[0] = -94.346461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750913584, states[0] = -94.353111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763236101, states[0] = -66.604534, states[40]= 0.000092
Saving checkpoint... 
Iteration: 775499015, states[0] = -94.308184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787896813, states[0] = -94.352698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799994644, states[0] = -94.346758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812330303, states[0] = -94.014485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824477099, states[0] = -94.291166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835889830, states[0] = -94.351359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848380221, states[0] = -94.158720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 861062994, states[0] = 27.116335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873705248, states[0] = -94.353822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 884849799, states[0] = -94.351501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897149058, states[0] = -11.087571, states[40]= 0.001313
Saving checkpoint... 
Iteration: 909724106, states[0] = -94.353003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922336814, states[0] = -94.034389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934721153, states[0] = -94.352064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947364835, states[0] = -94.118556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 959944977, states[0] = -94.343963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972482224, states[0] = -94.289778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984989472, states[0] = -94.340489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997571165, states[0] = -94.331516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010065096, states[0] = 26.417337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022584444, states[0] = -94.334117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035247323, states[0] = -82.940196, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1048094880, states[0] = 15.121824, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1060566608, states[0] = -94.327952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1073074570, states[0] = 23.055533, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1085983915, states[0] = -94.337232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098382482, states[0] = -94.154597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110941895, states[0] = -94.338780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123337437, states[0] = -94.029295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135734239, states[0] = -94.345115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147999462, states[0] = -94.334126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160097264, states[0] = 14.149391, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1172223884, states[0] = -55.419905, states[40]= 0.000479
Saving checkpoint... 
Iteration: 1184801208, states[0] = -94.342626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1197220143, states[0] = -52.427038, states[40]= 0.000730
Saving checkpoint... 
Iteration: 1209469340, states[0] = -94.271139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221985185, states[0] = -94.332346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234395166, states[0] = -94.174996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247029930, states[0] = 33.862436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259814506, states[0] = -94.339555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272698670, states[0] = -94.339431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285611963, states[0] = -94.330480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298096598, states[0] = 14.424684, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1310680991, states[0] = -94.337211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323035423, states[0] = 33.523966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335330756, states[0] = -93.997239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349232507, states[0] = -62.883875, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1361203238, states[0] = -39.958956, states[40]= 0.003400
Saving checkpoint... 
Iteration: 1374966583, states[0] = -94.328002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389380478, states[0] = -94.139848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404367387, states[0] = -94.108624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419318914, states[0] = -93.946100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433519068, states[0] = -94.296022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446770245, states[0] = -94.333978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461056453, states[0] = 29.166141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475403672, states[0] = -94.181443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489737078, states[0] = -94.332589, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.197542
 - CaMKt in component CaMK (millimolar): 0.009829
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 8.153220
 - nass in component intracellular_ions (millimolar): 8.153397
 - ki in component intracellular_ions (millimolar): 143.389390
 - kss in component intracellular_ions (millimolar): 143.389365
 - cansr in component intracellular_ions (millimolar): 2.120500
 - cajsr in component intracellular_ions (millimolar): 2.123036
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003885
 - hf in component INa (dimensionless): 0.867232
 - hs in component INa (dimensionless): 0.867234
 - j in component INa (dimensionless): 0.867248
 - hsp in component INa (dimensionless): 0.702250
 - jp in component INa (dimensionless): 0.867255
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709935
 - hLp in component INaL (dimensionless): 0.491759
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.871139
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.913367
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.959558
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005345
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.124890
 - xs1 in component IKs (dimensionless): 0.168739
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997516
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:55:32 (38899): called boinc_finish(0)

</stderr_txt>
]]>


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