𝕏

Task 56148988

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0
Workunit 26666099
Created 4 Jul 2024, 21:08:21 UTC
Sent 5 Jul 2024, 4:10:29 UTC
Report deadline 8 Jul 2024, 4:10:29 UTC
Received 5 Jul 2024, 15:34:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 163832
Run time 2 hours 15 min 8 sec
CPU time 1 hours 58 min 36 sec
Validate state Valid
Credit 42.71
Device peak FLOPS 2.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.23 MB
Peak disk usage 0.15 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0_r480144299_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0_r480144299_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.251564
     * GNaL_b in INaL: 0.005850
     * Gto_b in Ito: 0.084369
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.164219
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.560661
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032106
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11954153, states[0] = -84.589560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24116217, states[0] = -55.398126, states[40]= 0.000044
Saving checkpoint... 
Iteration: 36333268, states[0] = -79.333623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48497468, states[0] = -33.549187, states[40]= 0.000223
Saving checkpoint... 
Iteration: 60647870, states[0] = 16.518205, states[40]= 0.000010
Saving checkpoint... 
Iteration: 72671639, states[0] = -1.436144, states[40]= 0.000207
Saving checkpoint... 
Iteration: 84682342, states[0] = -14.709072, states[40]= 0.000216
Saving checkpoint... 
Iteration: 96846599, states[0] = 17.122256, states[40]= 0.000007
Saving checkpoint... 
Iteration: 109429946, states[0] = 26.146699, states[40]= 0.000048
Saving checkpoint... 
Iteration: 121267044, states[0] = 2.597221, states[40]= 0.000126
Saving checkpoint... 
Iteration: 130673941, states[0] = -4.236753, states[40]= 0.000221
Saving checkpoint... 
Iteration: 141871417, states[0] = -1.543951, states[40]= 0.000189
Saving checkpoint... 
Iteration: 152256826, states[0] = 10.455009, states[40]= 0.000034
Saving checkpoint... 
Iteration: 164989900, states[0] = -84.928336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177617839, states[0] = 30.387855, states[40]= 0.003772
Saving checkpoint... 
Iteration: 190210560, states[0] = 30.060529, states[40]= 0.055616
Saving checkpoint... 
Iteration: 202659212, states[0] = 8.751102, states[40]= 0.000047
Saving checkpoint... 
Iteration: 215361707, states[0] = -84.671309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228043530, states[0] = 18.882214, states[40]= 0.000004
Saving checkpoint... 
Iteration: 240650898, states[0] = 14.393228, states[40]= 0.000014
Saving checkpoint... 
Iteration: 253356844, states[0] = -84.609999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266016805, states[0] = 30.531194, states[40]= 0.005510
Saving checkpoint... 
Iteration: 278601020, states[0] = 34.836629, states[40]= 0.638811
Saving checkpoint... 
Iteration: 291178390, states[0] = -84.832348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303623120, states[0] = 28.979803, states[40]= 0.000553
Saving checkpoint... 
Iteration: 316164832, states[0] = -84.700769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328735145, states[0] = -82.319413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341431251, states[0] = 25.493935, states[40]= 0.000030
Saving checkpoint... 
Iteration: 354052687, states[0] = 13.239542, states[40]= 0.000018
Saving checkpoint... 
Iteration: 362916864, states[0] = -59.565942, states[40]= 0.000020
Saving checkpoint... 
Iteration: 373720301, states[0] = -64.297147, states[40]= 0.000011
Saving checkpoint... 
Iteration: 386381658, states[0] = -84.854783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398774004, states[0] = -84.787730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411265206, states[0] = 4.120237, states[40]= 0.000101
Saving checkpoint... 
Iteration: 423191809, states[0] = -84.929143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435149236, states[0] = -84.469037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446142328, states[0] = -84.125838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457022142, states[0] = 29.312868, states[40]= 0.000787
Saving checkpoint... 
Iteration: 467897398, states[0] = -34.902394, states[40]= 0.000172
Saving checkpoint... 
Iteration: 479272335, states[0] = -2.514440, states[40]= 0.000200
Saving checkpoint... 
Iteration: 490731833, states[0] = -79.921671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502241238, states[0] = 20.204090, states[40]= 0.000003
Saving checkpoint... 
Iteration: 513232559, states[0] = 24.851507, states[40]= 0.000019
Saving checkpoint... 
Iteration: 521882004, states[0] = -14.601734, states[40]= 0.000203
Saving checkpoint... 
Iteration: 533028311, states[0] = 26.878984, states[40]= 0.000086
Saving checkpoint... 
Iteration: 544325288, states[0] = -71.548624, states[40]= 0.000004
Saving checkpoint... 
Iteration: 550741307, states[0] = -84.008871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561831258, states[0] = 25.494989, states[40]= 0.000030
Saving checkpoint... 
Iteration: 572853002, states[0] = 13.038221, states[40]= 0.000019
Saving checkpoint... 
Iteration: 583898562, states[0] = -36.361865, states[40]= 0.000161
Saving checkpoint... 
Iteration: 594670795, states[0] = -0.928134, states[40]= 0.000178
Saving checkpoint... 
Iteration: 605295724, states[0] = -32.769649, states[40]= 0.000185
Saving checkpoint... 
Iteration: 615813506, states[0] = 30.598440, states[40]= 0.018612
Saving checkpoint... 
Iteration: 626583681, states[0] = -84.858603, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0_r480144299_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0_r480144299_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.251564
     * GNaL_b in INaL: 0.005850
     * Gto_b in Ito: 0.084369
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.164219
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.560661
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032106
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 626583681
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.858603 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 636473536, states[0] = -3.810644, states[40]= 0.000214
Saving checkpoint... 
Iteration: 648200839, states[0] = 33.315337, states[40]= 0.371522
Saving checkpoint... 
Iteration: 660151824, states[0] = -84.511778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672221992, states[0] = 29.365260, states[40]= 0.000831
Saving checkpoint... 
Iteration: 684251582, states[0] = 13.964336, states[40]= 0.000015
Saving checkpoint... 
Iteration: 696427621, states[0] = 27.189804, states[40]= 0.000110
Saving checkpoint... 
Iteration: 708619870, states[0] = 29.972440, states[40]= 0.001795
Saving checkpoint... 
Iteration: 721062553, states[0] = 6.256926, states[40]= 0.000073
Saving checkpoint... 
Iteration: 729625135, states[0] = 28.233528, states[40]= 0.000267
Saving checkpoint... 
Iteration: 741404399, states[0] = 30.124383, states[40]= 0.519081
Saving checkpoint... 
Iteration: 754045350, states[0] = 17.821627, states[40]= 0.000006
Saving checkpoint... 
Iteration: 766783952, states[0] = -84.853498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 779461181, states[0] = 7.308409, states[40]= 0.000061
Saving checkpoint... 
Iteration: 791961364, states[0] = -84.637333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804564071, states[0] = -84.667051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 817139701, states[0] = -83.750311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829707612, states[0] = -47.651844, states[40]= 0.000069
Saving checkpoint... 
Iteration: 842215556, states[0] = 30.639899, states[40]= 0.008719
Saving checkpoint... 
Iteration: 854800817, states[0] = 33.068824, states[40]= 0.339553
Saving checkpoint... 
Iteration: 865668686, states[0] = 1.100822, states[40]= 0.000147
Saving checkpoint... 
Iteration: 874700393, states[0] = -38.638242, states[40]= 0.000141
Saving checkpoint... 
Iteration: 886026885, states[0] = 27.513551, states[40]= 0.000143
Saving checkpoint... 
Iteration: 898550024, states[0] = -84.462518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911137752, states[0] = -83.291568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923790262, states[0] = -84.892548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936411137, states[0] = 30.216775, states[40]= 0.044839
Saving checkpoint... 
Iteration: 948798841, states[0] = -84.948017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961336442, states[0] = -82.842517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973900400, states[0] = -38.639725, states[40]= 0.000141
Saving checkpoint... 
Iteration: 986493684, states[0] = -30.133554, states[40]= 0.000193
Saving checkpoint... 
Iteration: 998847876, states[0] = 16.300820, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1011451355, states[0] = 14.117827, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1024094077, states[0] = -30.635563, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1036796535, states[0] = -84.929021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049254960, states[0] = 11.745596, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1061815762, states[0] = 30.633228, states[40]= 0.008079
Saving checkpoint... 
Iteration: 1074261580, states[0] = 7.014703, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1086803557, states[0] = 31.770123, states[40]= 0.695131
Saving checkpoint... 
Iteration: 1099315594, states[0] = -57.803219, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1111710176, states[0] = -50.847349, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1124176340, states[0] = -84.771284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136190679, states[0] = -84.884560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144206935, states[0] = 29.016938, states[40]= 0.210578
Saving checkpoint... 
Iteration: 1155446530, states[0] = 17.123244, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1167918938, states[0] = -62.297343, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1176173282, states[0] = -84.740684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188017704, states[0] = 30.425287, states[40]= 0.003957
Saving checkpoint... 
Iteration: 1200254790, states[0] = 11.863950, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1209414428, states[0] = 30.657388, states[40]= 0.013218
Saving checkpoint... 
Iteration: 1221586428, states[0] = -84.849117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234227386, states[0] = 27.303669, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1246878321, states[0] = -9.595943, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1259541314, states[0] = -83.962594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272054219, states[0] = 12.248750, states[40]= 0.000023


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0_r480144299_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_857_0_r480144299_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.251564
     * GNaL_b in INaL: 0.005850
     * Gto_b in Ito: 0.084369
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031805
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.164219
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.560661
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032106
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1272054219
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 12.248750 (After loading)
 - states[40]: 0.000023 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1281260222, states[0] = 8.038379, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1291035108, states[0] = 23.562865, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1300673983, states[0] = -4.278775, states[40]= 0.000218
Saving checkpoint... 
Iteration: 1310345191, states[0] = -84.275959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320235047, states[0] = 23.595327, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1330176271, states[0] = -84.759993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341377789, states[0] = -84.772784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353890369, states[0] = -25.807474, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1366493049, states[0] = -29.289208, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1379104407, states[0] = -43.608889, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1391456164, states[0] = 10.933103, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1403834226, states[0] = 24.022916, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1412977119, states[0] = -84.763213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1425552462, states[0] = -84.482371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437934405, states[0] = -81.782118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445883986, states[0] = -17.251511, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1456866944, states[0] = 2.680339, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1469306411, states[0] = -46.099918, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1481812015, states[0] = 30.410825, states[40]= 0.032331
Saving checkpoint... 
Iteration: 1494396244, states[0] = -84.903643, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.802502
 - CaMKt in component CaMK (millimolar): 0.148671
 - cass in component intracellular_ions (millimolar): 0.000143
 - nai in component intracellular_ions (millimolar): 7.145066
 - nass in component intracellular_ions (millimolar): 7.145333
 - ki in component intracellular_ions (millimolar): 144.125728
 - kss in component intracellular_ions (millimolar): 144.125694
 - cansr in component intracellular_ions (millimolar): 2.942550
 - cajsr in component intracellular_ions (millimolar): 1.954785
 - cai in component intracellular_ions (millimolar): 0.000137
 - m in component INa (dimensionless): 0.010002
 - hf in component INa (dimensionless): 0.582482
 - hs in component INa (dimensionless): 0.581828
 - j in component INa (dimensionless): 0.574032
 - hsp in component INa (dimensionless): 0.332906
 - jp in component INa (dimensionless): 0.557166
 - mL in component INaL (dimensionless): 0.000338
 - hL in component INaL (dimensionless): 0.236582
 - hLp in component INaL (dimensionless): 0.097266
 - a in component Ito (dimensionless): 0.001232
 - iF in component Ito (dimensionless): 0.999233
 - iS in component Ito (dimensionless): 0.180294
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999234
 - iSp in component Ito (dimensionless): 0.200789
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.725030
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.957352
 - jca in component ICaL (dimensionless): 0.956754
 - ffp in component ICaL (dimensionless): 0.999936
 - fcafp in component ICaL (dimensionless): 0.999997
 - nca in component ICaL (dimensionless): 0.020438
 - xrf in component IKr (dimensionless): 0.036309
 - xrs in component IKr (dimensionless): 0.833373
 - xs1 in component IKs (dimensionless): 0.525166
 - xs2 in component IKs (dimensionless): 0.001509
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
16:33:17 (14612): called boinc_finish(0)

</stderr_txt>
]]>


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