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Task 56148257

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_457_0
Workunit 26665734
Created 4 Jul 2024, 21:08:00 UTC
Sent 5 Jul 2024, 4:09:22 UTC
Report deadline 8 Jul 2024, 7:02:10 UTC
Received 5 Jul 2024, 8:12:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218513
Run time 50 min 35 sec
CPU time 45 min 31 sec
Validate state Valid
Credit 47.97
Device peak FLOPS 4.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.78 MB
Peak swap size 391.76 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_457.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_457_0_r1374498805_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_457_0_r1374498805_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.311867
     * GNaL_b in INaL: 0.005753
     * Gto_b in Ito: 0.084933
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009546
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.162683
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.140977
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032888
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 25572432, states[0] = 15.433867, states[40]= 0.004642
Saving checkpoint... 
Iteration: 53699983, states[0] = -31.032255, states[40]= 0.003211
Saving checkpoint... 
Iteration: 81676364, states[0] = -22.861484, states[40]= 0.005146
Saving checkpoint... 
Iteration: 107489820, states[0] = -94.766174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133276865, states[0] = -60.906154, states[40]= 0.000036
Saving checkpoint... 
Iteration: 161512317, states[0] = 30.797431, states[40]= 0.022708
Saving checkpoint... 
Iteration: 190930295, states[0] = -94.728682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217126806, states[0] = -2.756974, states[40]= 0.004295
Saving checkpoint... 
Iteration: 244151181, states[0] = -13.263024, states[40]= 0.002640
Saving checkpoint... 
Iteration: 271520148, states[0] = 30.751338, states[40]= 0.004047
Saving checkpoint... 
Iteration: 298092478, states[0] = 10.008488, states[40]= 0.005158
Saving checkpoint... 
Iteration: 323118189, states[0] = 0.680775, states[40]= 0.004807
Saving checkpoint... 
Iteration: 351712354, states[0] = -32.841197, states[40]= 0.002565
Saving checkpoint... 
Iteration: 377715363, states[0] = -33.834791, states[40]= 0.002287
Saving checkpoint... 
Iteration: 403192841, states[0] = -26.837583, states[40]= 0.004453
Saving checkpoint... 
Iteration: 430861768, states[0] = -94.661828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458271136, states[0] = -56.831782, states[40]= 0.000073
Saving checkpoint... 
Iteration: 487057682, states[0] = 21.202720, states[40]= 0.004062
Saving checkpoint... 
Iteration: 516463778, states[0] = -94.745137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542285600, states[0] = -66.038042, states[40]= 0.000015
Saving checkpoint... 
Iteration: 569325540, states[0] = -94.588878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596067560, states[0] = 18.217126, states[40]= 0.004555
Saving checkpoint... 
Iteration: 623484589, states[0] = -94.753615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652498414, states[0] = -94.758417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678762959, states[0] = -52.737076, states[40]= 0.000146
Saving checkpoint... 
Iteration: 706137785, states[0] = -7.392771, states[40]= 0.003335
Saving checkpoint... 
Iteration: 733655377, states[0] = -14.976759, states[40]= 0.002839
Saving checkpoint... 
Iteration: 761949003, states[0] = -94.737124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788434853, states[0] = -94.728840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814972296, states[0] = -94.748209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842348123, states[0] = -94.641508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870772360, states[0] = -57.487831, states[40]= 0.000065
Saving checkpoint... 
Iteration: 897491048, states[0] = -94.755309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923009097, states[0] = 30.640181, states[40]= 0.061388
Saving checkpoint... 
Iteration: 948773081, states[0] = -57.882130, states[40]= 0.000061
Saving checkpoint... 
Iteration: 976753067, states[0] = -48.245037, states[40]= 0.000306
Saving checkpoint... 
Iteration: 1002032856, states[0] = 28.265501, states[40]= 0.002843
Saving checkpoint... 
Iteration: 1028482033, states[0] = -94.751652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055557343, states[0] = 21.303392, states[40]= 0.004043
Saving checkpoint... 
Iteration: 1083106226, states[0] = 5.140988, states[40]= 0.005128
Saving checkpoint... 
Iteration: 1109950461, states[0] = -94.737058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136535133, states[0] = 27.667404, states[40]= 0.002909
Saving checkpoint... 
Iteration: 1163000411, states[0] = -43.273063, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1188777010, states[0] = -60.139928, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1215236368, states[0] = -41.383534, states[40]= 0.000858
Saving checkpoint... 
Iteration: 1244262889, states[0] = -52.702114, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1270065593, states[0] = 18.823553, states[40]= 0.004467
Saving checkpoint... 
Iteration: 1295886619, states[0] = -94.688699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324669391, states[0] = -19.950723, states[40]= 0.004733
Saving checkpoint... 
Iteration: 1350134923, states[0] = -6.146806, states[40]= 0.003600
Saving checkpoint... 
Iteration: 1377762942, states[0] = -52.726882, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1405193053, states[0] = -26.897737, states[40]= 0.004435
Saving checkpoint... 
Iteration: 1433684066, states[0] = -24.304439, states[40]= 0.005008
Saving checkpoint... 
Iteration: 1460373030, states[0] = -94.673362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488381080, states[0] = -94.682392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515266503, states[0] = -94.765058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542543077, states[0] = -48.899147, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1567487211, states[0] = -94.491200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593257829, states[0] = -94.475797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620071161, states[0] = 21.333152, states[40]= 0.003622
Saving checkpoint... 
Iteration: 1644154332, states[0] = -94.400961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669686126, states[0] = -94.392679, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.265655
 - CaMKt in component CaMK (millimolar): 0.001266
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.169447
 - nass in component intracellular_ions (millimolar): 6.169520
 - ki in component intracellular_ions (millimolar): 145.756929
 - kss in component intracellular_ions (millimolar): 145.756922
 - cansr in component intracellular_ions (millimolar): 1.482560
 - cajsr in component intracellular_ions (millimolar): 1.482034
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003859
 - hf in component INa (dimensionless): 0.868514
 - hs in component INa (dimensionless): 0.868515
 - j in component INa (dimensionless): 0.868516
 - hsp in component INa (dimensionless): 0.704572
 - jp in component INa (dimensionless): 0.868517
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712079
 - hLp in component INaL (dimensionless): 0.518973
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.995872
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.998504
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997538
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002464
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003577
 - xs1 in component IKs (dimensionless): 0.036578
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997499
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:09:45 (3130): called boinc_finish(0)

</stderr_txt>
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