𝕏

Task 56147780

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_656_0
Workunit 26665497
Created 4 Jul 2024, 21:07:44 UTC
Sent 5 Jul 2024, 3:59:30 UTC
Report deadline 8 Jul 2024, 3:59:30 UTC
Received 5 Jul 2024, 22:57:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215304
Run time 53 min 19 sec
CPU time 53 min 19 sec
Validate state Valid
Credit 46.28
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.77 MB
Peak swap size 6.23 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_656.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_656_0_r396375720_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_656_0_r396375720_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.686875
     * GNaL_b in INaL: 0.005844
     * Gto_b in Ito: 0.083985
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031932
     * GKs_b in IKs: 0.001923
     * GK1_b in IK1: 0.162994
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.358485
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032739
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9401986, states[0] = -87.328948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18556900, states[0] = 0.006518, states[40]= 0.004944
Saving checkpoint... 
Iteration: 29685097, states[0] = -87.356548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39322433, states[0] = -15.409844, states[40]= 0.001663
Saving checkpoint... 
Iteration: 48719816, states[0] = -87.407227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58000306, states[0] = -49.596264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68334944, states[0] = -30.276980, states[40]= 0.000432
Saving checkpoint... 
Iteration: 78534084, states[0] = 14.733425, states[40]= 0.006484
Saving checkpoint... 
Iteration: 88411054, states[0] = -87.269540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98204628, states[0] = -87.370465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107533862, states[0] = 14.878682, states[40]= 0.006504
Saving checkpoint... 
Iteration: 116864928, states[0] = -68.937533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126217023, states[0] = -87.390047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136203517, states[0] = -87.366533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146817371, states[0] = -8.841010, states[40]= 0.003043
Saving checkpoint... 
Iteration: 156921321, states[0] = -87.294567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166558009, states[0] = -0.052954, states[40]= 0.004966
Saving checkpoint... 
Iteration: 176026391, states[0] = 18.434496, states[40]= 0.007485
Saving checkpoint... 
Iteration: 185370934, states[0] = -78.314375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194804595, states[0] = 2.505566, states[40]= 0.005314
Saving checkpoint... 
Iteration: 205072199, states[0] = -14.444660, states[40]= 0.001826
Saving checkpoint... 
Iteration: 215147164, states[0] = -87.217542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225020357, states[0] = 20.794444, states[40]= 0.009858
Saving checkpoint... 
Iteration: 234626271, states[0] = -84.312666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244102113, states[0] = -51.077023, states[40]= 0.000025
Saving checkpoint... 
Iteration: 253538388, states[0] = 12.504570, states[40]= 0.006193
Saving checkpoint... 
Iteration: 263602434, states[0] = -51.487890, states[40]= 0.000023
Saving checkpoint... 
Iteration: 273877864, states[0] = -85.284536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283918270, states[0] = -87.285975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293706842, states[0] = -87.371711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303258848, states[0] = 24.094901, states[40]= 0.059947
Saving checkpoint... 
Iteration: 312740762, states[0] = -87.421935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322173338, states[0] = -87.299271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331513605, states[0] = 22.756966, states[40]= 0.022410
Saving checkpoint... 
Iteration: 342639139, states[0] = -87.127025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352481645, states[0] = -87.410236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362205022, states[0] = -87.368354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371728857, states[0] = -87.406404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381017307, states[0] = 21.770470, states[40]= 0.013034
Saving checkpoint... 
Iteration: 390458552, states[0] = -87.374634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399785530, states[0] = 14.034627, states[40]= 0.006376
Saving checkpoint... 
Iteration: 409910366, states[0] = -87.263661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419864586, states[0] = -68.321739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429727187, states[0] = -87.404002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439470188, states[0] = -87.393673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448825448, states[0] = -18.405788, states[40]= 0.001244
Saving checkpoint... 
Iteration: 458202715, states[0] = -87.363995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468049465, states[0] = 5.967324, states[40]= 0.005649
Saving checkpoint... 
Iteration: 478181648, states[0] = -87.319568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488246636, states[0] = -87.428652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498046642, states[0] = 7.734730, states[40]= 0.005788
Saving checkpoint... 
Iteration: 507750578, states[0] = 34.435047, states[40]= 0.002715
Saving checkpoint... 
Iteration: 517020621, states[0] = 20.703057, states[40]= 0.009679
Saving checkpoint... 
Iteration: 526372013, states[0] = -79.837449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536878819, states[0] = -85.716816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547074019, states[0] = -16.654972, states[40]= 0.001470
Saving checkpoint... 
Iteration: 557083682, states[0] = -28.467162, states[40]= 0.000517
Saving checkpoint... 
Iteration: 566953685, states[0] = -87.365690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576561240, states[0] = -2.738141, states[40]= 0.004480
Saving checkpoint... 
Iteration: 586073530, states[0] = -16.057796, states[40]= 0.001559
Saving checkpoint... 
Iteration: 595500086, states[0] = -76.830304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604933941, states[0] = -87.324780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615173506, states[0] = -87.299402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625681535, states[0] = -87.319151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635441192, states[0] = -87.340801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645500799, states[0] = 39.304588, states[40]= 0.015612
Saving checkpoint... 
Iteration: 655190278, states[0] = -87.338826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664745799, states[0] = -87.427518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674189525, states[0] = -87.337182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683540706, states[0] = 11.219157, states[40]= 0.006067
Saving checkpoint... 
Iteration: 692948841, states[0] = -87.356347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703355186, states[0] = -55.055617, states[40]= 0.000013
Saving checkpoint... 
Iteration: 713802937, states[0] = 3.667635, states[40]= 0.005440
Saving checkpoint... 
Iteration: 723656806, states[0] = -87.252674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733213993, states[0] = -87.383528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742645805, states[0] = -87.209396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751981022, states[0] = -87.408990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761988320, states[0] = -87.418473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772333107, states[0] = -27.769019, states[40]= 0.000552
Saving checkpoint... 
Iteration: 782526605, states[0] = 18.343542, states[40]= 0.007440
Saving checkpoint... 
Iteration: 791916494, states[0] = -87.280619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801227917, states[0] = -87.404655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811693883, states[0] = -87.346263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822013073, states[0] = 22.886640, states[40]= 0.024692
Saving checkpoint... 
Iteration: 831158644, states[0] = -87.258138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840291448, states[0] = 10.799078, states[40]= 0.006030
Saving checkpoint... 
Iteration: 847996988, states[0] = -87.428687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855298999, states[0] = 6.264984, states[40]= 0.005673
Saving checkpoint... 
Iteration: 862982823, states[0] = -87.411294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870903749, states[0] = -87.242800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878943753, states[0] = -87.345926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886795920, states[0] = 8.174542, states[40]= 0.005821
Saving checkpoint... 
Iteration: 894393765, states[0] = -87.194570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902372956, states[0] = -81.062251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910915395, states[0] = -87.277465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919584577, states[0] = -29.551383, states[40]= 0.000465
Saving checkpoint... 
Iteration: 928305590, states[0] = 1.788441, states[40]= 0.005227
Saving checkpoint... 
Iteration: 936578994, states[0] = -22.754302, states[40]= 0.000847
Saving checkpoint... 
Iteration: 945788279, states[0] = 12.564513, states[40]= 0.006199
Saving checkpoint... 
Iteration: 955321886, states[0] = -14.063614, states[40]= 0.001895
Saving checkpoint... 
Iteration: 964949176, states[0] = -87.356724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974455595, states[0] = -87.368774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984157126, states[0] = -87.253390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993876451, states[0] = -84.437400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002594367, states[0] = -41.395285, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1011884331, states[0] = -86.885377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021410726, states[0] = -87.264087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031557495, states[0] = 0.354301, states[40]= 0.005028
Saving checkpoint... 
Iteration: 1041485086, states[0] = -87.414081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051448512, states[0] = -87.355339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060881920, states[0] = -86.573489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070321350, states[0] = -13.420002, states[40]= 0.002017
Saving checkpoint... 
Iteration: 1080382738, states[0] = -86.703340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090670637, states[0] = -87.291459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100777918, states[0] = 17.762160, states[40]= 0.007199
Saving checkpoint... 
Iteration: 1110571250, states[0] = -13.300357, states[40]= 0.002040
Saving checkpoint... 
Iteration: 1120348142, states[0] = -46.056455, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1129888732, states[0] = -87.115677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139409546, states[0] = -87.260505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149146908, states[0] = -87.215202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158732079, states[0] = -87.410002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168169067, states[0] = -87.287209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178542035, states[0] = 10.463867, states[40]= 0.006002
Saving checkpoint... 
Iteration: 1188032966, states[0] = 15.351963, states[40]= 0.006582
Saving checkpoint... 
Iteration: 1197501635, states[0] = 40.853942, states[40]= 0.071839
Saving checkpoint... 
Iteration: 1206869973, states[0] = -76.849703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216287754, states[0] = 12.849825, states[40]= 0.006230
Saving checkpoint... 
Iteration: 1226688445, states[0] = -87.334266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236868639, states[0] = -74.750064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246906197, states[0] = -87.250254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256743370, states[0] = -87.424097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266449476, states[0] = -87.357001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275970648, states[0] = -87.393529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286493079, states[0] = -87.423723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296671008, states[0] = -87.292225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305968487, states[0] = -87.390160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316350215, states[0] = -48.660061, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1326329702, states[0] = -23.619789, states[40]= 0.000788
Saving checkpoint... 
Iteration: 1336406262, states[0] = -87.250365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346090233, states[0] = -36.379231, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1355613317, states[0] = -66.384858, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1364966981, states[0] = -87.387724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374386936, states[0] = -87.052830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383783486, states[0] = 15.089601, states[40]= 0.006536
Saving checkpoint... 
Iteration: 1394142362, states[0] = -87.180236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404902313, states[0] = -87.237386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414535179, states[0] = 14.218652, states[40]= 0.006401
Saving checkpoint... 
Iteration: 1424060296, states[0] = -1.918793, states[40]= 0.004641
Saving checkpoint... 
Iteration: 1433451599, states[0] = -87.360903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442773626, states[0] = 19.582260, states[40]= 0.008232
Saving checkpoint... 
Iteration: 1452162720, states[0] = -87.269392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462537008, states[0] = 13.251627, states[40]= 0.006276
Saving checkpoint... 
Iteration: 1472682087, states[0] = -87.319588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482443044, states[0] = -87.343840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492159857, states[0] = -87.261062, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.307130
 - CaMKt in component CaMK (millimolar): 0.019323
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.742261
 - nass in component intracellular_ions (millimolar): 6.742361
 - ki in component intracellular_ions (millimolar): 145.215447
 - kss in component intracellular_ions (millimolar): 145.215420
 - cansr in component intracellular_ions (millimolar): 1.423591
 - cajsr in component intracellular_ions (millimolar): 1.206593
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007778
 - hf in component INa (dimensionless): 0.677990
 - hs in component INa (dimensionless): 0.677888
 - j in component INa (dimensionless): 0.677195
 - hsp in component INa (dimensionless): 0.431513
 - jp in component INa (dimensionless): 0.675268
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.387468
 - hLp in component INaL (dimensionless): 0.181671
 - a in component Ito (dimensionless): 0.001040
 - iF in component Ito (dimensionless): 0.999507
 - iS in component Ito (dimensionless): 0.293591
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999507
 - iSp in component Ito (dimensionless): 0.341313
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857693
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991062
 - jca in component ICaL (dimensionless): 0.991420
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004184
 - xrf in component IKr (dimensionless): 0.001735
 - xrs in component IKr (dimensionless): 0.673876
 - xs1 in component IKs (dimensionless): 0.383102
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996908
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:53:29 (17688): called boinc_finish(0)

</stderr_txt>
]]>


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