𝕏

Task 56144049

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_353_0
Workunit 26663633
Created 4 Jul 2024, 21:05:59 UTC
Sent 5 Jul 2024, 3:35:49 UTC
Report deadline 8 Jul 2024, 3:35:49 UTC
Received 5 Jul 2024, 11:35:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 18 min 21 sec
CPU time 2 hours 15 min 51 sec
Validate state Valid
Credit 43.09
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 4.08 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_353.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_353_0_r1565566938_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_353_0_r1565566938_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.041340
     * GNaL_b in INaL: 0.005837
     * Gto_b in Ito: 0.085304
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031794
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.162949
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.606217
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032921
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11336790, states[0] = -94.927008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22684855, states[0] = -94.470753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34000422, states[0] = -41.938640, states[40]= 0.000007
Saving checkpoint... 
Iteration: 45307581, states[0] = -94.822837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56600400, states[0] = -12.978259, states[40]= 0.002063
Saving checkpoint... 
Iteration: 67903883, states[0] = -94.905492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79236285, states[0] = -94.659637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90588994, states[0] = -2.690373, states[40]= 0.004203
Saving checkpoint... 
Iteration: 101895168, states[0] = -94.897835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113219278, states[0] = -94.598713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124541150, states[0] = 20.820852, states[40]= 0.002155
Saving checkpoint... 
Iteration: 135866534, states[0] = -94.877340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147157690, states[0] = -72.366788, states[40]= 0.000002
Saving checkpoint... 
Iteration: 158449558, states[0] = -94.920884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169755405, states[0] = -94.711225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181080704, states[0] = 2.966815, states[40]= 0.004668
Saving checkpoint... 
Iteration: 192386887, states[0] = -94.891071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203720678, states[0] = -94.602633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215044612, states[0] = 19.549430, states[40]= 0.002394
Saving checkpoint... 
Iteration: 226350656, states[0] = -94.862987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237655310, states[0] = -69.085736, states[40]= 0.000004
Saving checkpoint... 
Iteration: 248943022, states[0] = -94.917996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260259791, states[0] = -94.721681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271604474, states[0] = -16.735432, states[40]= 0.001529
Saving checkpoint... 
Iteration: 282920944, states[0] = -94.908938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294235804, states[0] = -94.654355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305552523, states[0] = 16.488448, states[40]= 0.003004
Saving checkpoint... 
Iteration: 316843586, states[0] = -94.855829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328181720, states[0] = -94.300806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339501289, states[0] = 48.055603, states[40]= 0.267026
Saving checkpoint... 
Iteration: 350823840, states[0] = -94.833933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362135013, states[0] = -46.463323, states[40]= 0.000154
Saving checkpoint... 
Iteration: 373446200, states[0] = -94.918608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384753985, states[0] = -94.706490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396066677, states[0] = 10.390676, states[40]= 0.004115
Saving checkpoint... 
Iteration: 407385558, states[0] = -94.889264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418700298, states[0] = -94.518043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430012537, states[0] = 27.636767, states[40]= 0.021326
Saving checkpoint... 
Iteration: 441279345, states[0] = -94.763981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452602192, states[0] = -14.480747, states[40]= 0.001817
Saving checkpoint... 
Iteration: 463866533, states[0] = -94.875502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475161993, states[0] = -78.917231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486487164, states[0] = -94.929795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497823659, states[0] = -94.833122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509152768, states[0] = -65.871329, states[40]= 0.000007
Saving checkpoint... 
Iteration: 520466241, states[0] = -94.924333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531789762, states[0] = -94.783034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543122441, states[0] = -34.003116, states[40]= 0.000720
Saving checkpoint... 
Iteration: 554442162, states[0] = -94.916448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565737866, states[0] = -94.659743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577035581, states[0] = 22.795226, states[40]= 0.001836
Saving checkpoint... 
Iteration: 588362115, states[0] = -94.871466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599680228, states[0] = -94.216883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610995684, states[0] = -94.931150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622325602, states[0] = -94.834975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633597085, states[0] = -9.532318, states[40]= 0.002775
Saving checkpoint... 
Iteration: 644923596, states[0] = -94.908666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656244983, states[0] = -94.680699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667569093, states[0] = 9.236760, states[40]= 0.004271
Saving checkpoint... 
Iteration: 678903122, states[0] = -94.898552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690219598, states[0] = -94.596554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701524740, states[0] = 26.035241, states[40]= 0.001672
Saving checkpoint... 
Iteration: 712850772, states[0] = -94.861112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724162955, states[0] = -80.494533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735489818, states[0] = -94.929397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746806585, states[0] = -94.809232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758128637, states[0] = -40.019458, states[40]= 0.000366
Saving checkpoint... 
Iteration: 769430434, states[0] = -94.911066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780750193, states[0] = -94.694788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792057468, states[0] = 14.465699, states[40]= 0.003409
Saving checkpoint... 
Iteration: 803360347, states[0] = -94.869145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814671708, states[0] = -91.904740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826009175, states[0] = 27.738471, states[40]= 0.064667
Saving checkpoint... 
Iteration: 837312038, states[0] = -94.816638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848644681, states[0] = -56.683443, states[40]= 0.000033
Saving checkpoint... 
Iteration: 859978317, states[0] = -94.926195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871291749, states[0] = -94.785130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882597966, states[0] = -10.365022, states[40]= 0.002591
Saving checkpoint... 
Iteration: 893921001, states[0] = -94.906519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905202090, states[0] = -94.524133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916503347, states[0] = 36.347634, states[40]= 0.420472
Saving checkpoint... 
Iteration: 927805464, states[0] = -94.806852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939108686, states[0] = -20.859155, states[40]= 0.001267
Saving checkpoint... 
Iteration: 950425315, states[0] = -94.908194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961714964, states[0] = -94.577637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972965625, states[0] = -94.922353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984236043, states[0] = -94.652322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995525235, states[0] = 25.913647, states[40]= 0.001640
Saving checkpoint... 
Iteration: 1006830367, states[0] = -94.839002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018140756, states[0] = -52.478799, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1029464485, states[0] = -94.921800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040788259, states[0] = -94.778323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052138615, states[0] = -50.216402, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1063443040, states[0] = -94.914735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074728200, states[0] = -94.625995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086033562, states[0] = 23.470561, states[40]= 0.001739
Saving checkpoint... 
Iteration: 1097358930, states[0] = -94.866779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108681273, states[0] = -94.275910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119992247, states[0] = -94.928394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131312093, states[0] = -94.815536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142610623, states[0] = -22.729278, states[40]= 0.001227
Saving checkpoint... 
Iteration: 1153900459, states[0] = -94.895199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165204782, states[0] = -94.534868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176500814, states[0] = 44.275100, states[40]= 0.082485
Saving checkpoint... 
Iteration: 1187800283, states[0] = -94.797898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199103646, states[0] = -15.914026, states[40]= 0.001621
Saving checkpoint... 
Iteration: 1210410040, states[0] = -94.900035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221704253, states[0] = -94.532349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233037099, states[0] = 22.274061, states[40]= 0.001917
Saving checkpoint... 
Iteration: 1244337749, states[0] = -94.846144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255672568, states[0] = -92.419271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266973658, states[0] = -94.923379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278307893, states[0] = -94.809006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289614584, states[0] = -26.513740, states[40]= 0.001154
Saving checkpoint... 
Iteration: 1300787193, states[0] = -94.775361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312092573, states[0] = -5.492107, states[40]= 0.003685
Saving checkpoint... 
Iteration: 1323414449, states[0] = -94.901754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334697402, states[0] = -94.500750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346019737, states[0] = 27.057282, states[40]= 0.002944
Saving checkpoint... 
Iteration: 1357332398, states[0] = -94.839888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368638827, states[0] = -50.437928, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1379983786, states[0] = -94.925449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391321826, states[0] = -94.827280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402658193, states[0] = -73.039191, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1413953055, states[0] = -94.916763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425253591, states[0] = -94.701267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436566205, states[0] = 10.613031, states[40]= 0.004083
Saving checkpoint... 
Iteration: 1447868245, states[0] = -94.872898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459200801, states[0] = -94.516101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470520212, states[0] = 26.979315, states[40]= 0.002697
Saving checkpoint... 
Iteration: 1481860292, states[0] = -94.866386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493165120, states[0] = -84.044751, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.804357
 - CaMKt in component CaMK (millimolar): 0.012794
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.731941
 - nass in component intracellular_ions (millimolar): 6.732039
 - ki in component intracellular_ions (millimolar): 145.147592
 - kss in component intracellular_ions (millimolar): 145.147570
 - cansr in component intracellular_ions (millimolar): 1.673184
 - cajsr in component intracellular_ions (millimolar): 1.631544
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003654
 - hf in component INa (dimensionless): 0.878299
 - hs in component INa (dimensionless): 0.878291
 - j in component INa (dimensionless): 0.878239
 - hsp in component INa (dimensionless): 0.722611
 - jp in component INa (dimensionless): 0.878204
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704765
 - hLp in component INaL (dimensionless): 0.441994
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.611644
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.682566
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916294
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999835
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003096
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.365336
 - xs1 in component IKs (dimensionless): 0.267043
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997363
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:54:28 (20561): called boinc_finish(0)

</stderr_txt>
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