𝕏

Task 56143646

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_252_0
Workunit 26663432
Created 4 Jul 2024, 21:05:44 UTC
Sent 5 Jul 2024, 3:35:49 UTC
Report deadline 8 Jul 2024, 3:35:49 UTC
Received 5 Jul 2024, 6:55:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 19 min 25 sec
CPU time 2 hours 16 min 55 sec
Validate state Valid
Credit 44.92
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.80 MB
Peak swap size 4.08 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_252.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_252_0_r1364972178_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_252_0_r1364972178_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.779174
     * GNaL_b in INaL: 0.005868
     * Gto_b in Ito: 0.083659
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031948
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.163997
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.271285
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032719
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11153157, states[0] = -84.945351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22381337, states[0] = 13.189623, states[40]= 0.000088
Saving checkpoint... 
Iteration: 33602226, states[0] = -51.718580, states[40]= 0.000100
Saving checkpoint... 
Iteration: 44809285, states[0] = -84.773486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56061309, states[0] = -1.315191, states[40]= 0.000315
Saving checkpoint... 
Iteration: 67290235, states[0] = -83.615253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78492248, states[0] = -72.958166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89697915, states[0] = 18.917161, states[40]= 0.000006
Saving checkpoint... 
Iteration: 100941996, states[0] = -73.837703, states[40]= 0.000006
Saving checkpoint... 
Iteration: 112163738, states[0] = 28.475076, states[40]= 0.126643
Saving checkpoint... 
Iteration: 123385110, states[0] = 0.936378, states[40]= 0.000206
Saving checkpoint... 
Iteration: 134578152, states[0] = -36.167344, states[40]= 0.000241
Saving checkpoint... 
Iteration: 145794102, states[0] = -84.738036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157006218, states[0] = 28.076547, states[40]= 0.000839
Saving checkpoint... 
Iteration: 168267310, states[0] = -72.210357, states[40]= 0.000007
Saving checkpoint... 
Iteration: 179462458, states[0] = -84.826555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190654899, states[0] = 28.242926, states[40]= 0.182181
Saving checkpoint... 
Iteration: 201886048, states[0] = -9.737558, states[40]= 0.000324
Saving checkpoint... 
Iteration: 213132135, states[0] = -84.910492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224346518, states[0] = 21.525977, states[40]= 0.000008
Saving checkpoint... 
Iteration: 235568541, states[0] = -36.888721, states[40]= 0.000231
Saving checkpoint... 
Iteration: 246812092, states[0] = 31.338669, states[40]= 0.715126
Saving checkpoint... 
Iteration: 258069895, states[0] = -41.691644, states[40]= 0.000175
Saving checkpoint... 
Iteration: 269306867, states[0] = -12.270896, states[40]= 0.000729
Saving checkpoint... 
Iteration: 280554888, states[0] = -24.301241, states[40]= 0.000262
Saving checkpoint... 
Iteration: 291831315, states[0] = 25.926292, states[40]= 0.000127
Saving checkpoint... 
Iteration: 303043808, states[0] = -11.469443, states[40]= 0.000315
Saving checkpoint... 
Iteration: 314293202, states[0] = -84.957662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325548148, states[0] = -21.094843, states[40]= 0.000255
Saving checkpoint... 
Iteration: 336795250, states[0] = -85.002786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348009367, states[0] = 16.375795, states[40]= 0.000009
Saving checkpoint... 
Iteration: 359229289, states[0] = -45.450191, states[40]= 0.000131
Saving checkpoint... 
Iteration: 370487342, states[0] = 27.142452, states[40]= 0.000344
Saving checkpoint... 
Iteration: 381733155, states[0] = -53.583530, states[40]= 0.000062
Saving checkpoint... 
Iteration: 392987032, states[0] = 26.308936, states[40]= 0.000172
Saving checkpoint... 
Iteration: 404217803, states[0] = -36.153915, states[40]= 0.000239
Saving checkpoint... 
Iteration: 415474856, states[0] = 29.402741, states[40]= 0.006251
Saving checkpoint... 
Iteration: 426724068, states[0] = -47.466019, states[40]= 0.000111
Saving checkpoint... 
Iteration: 437993654, states[0] = 20.477200, states[40]= 0.000006
Saving checkpoint... 
Iteration: 449232103, states[0] = -61.467826, states[40]= 0.000027
Saving checkpoint... 
Iteration: 460473768, states[0] = 28.728304, states[40]= 0.001795
Saving checkpoint... 
Iteration: 471718801, states[0] = -46.446663, states[40]= 0.000121
Saving checkpoint... 
Iteration: 482974198, states[0] = 27.875682, states[40]= 0.000680
Saving checkpoint... 
Iteration: 494226113, states[0] = -59.345399, states[40]= 0.000034
Saving checkpoint... 
Iteration: 505468127, states[0] = 29.013225, states[40]= 0.002720
Saving checkpoint... 
Iteration: 516721303, states[0] = -55.801457, states[40]= 0.000049
Saving checkpoint... 
Iteration: 527951020, states[0] = 30.451145, states[40]= 0.627524
Saving checkpoint... 
Iteration: 539183500, states[0] = -6.777225, states[40]= 0.000324
Saving checkpoint... 
Iteration: 550427410, states[0] = -84.833609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561667120, states[0] = 7.540466, states[40]= 0.000075
Saving checkpoint... 
Iteration: 572919976, states[0] = -84.751149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584168611, states[0] = 4.409804, states[40]= 0.000128
Saving checkpoint... 
Iteration: 595396170, states[0] = -78.930354, states[40]= 0.000002
Saving checkpoint... 
Iteration: 606633853, states[0] = 25.608317, states[40]= 0.000100
Saving checkpoint... 
Iteration: 617889233, states[0] = -72.502756, states[40]= 0.000007
Saving checkpoint... 
Iteration: 629138576, states[0] = 21.978392, states[40]= 0.000010
Saving checkpoint... 
Iteration: 640417516, states[0] = -84.815485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651653290, states[0] = 11.205845, states[40]= 0.000035
Saving checkpoint... 
Iteration: 662900747, states[0] = -84.317336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674115194, states[0] = 29.453908, states[40]= 0.007407
Saving checkpoint... 
Iteration: 685358826, states[0] = -39.440248, states[40]= 0.000201
Saving checkpoint... 
Iteration: 696610916, states[0] = 29.517801, states[40]= 0.015671
Saving checkpoint... 
Iteration: 707876884, states[0] = -67.333522, states[40]= 0.000013
Saving checkpoint... 
Iteration: 719110142, states[0] = 29.496905, states[40]= 0.009078
Saving checkpoint... 
Iteration: 730345664, states[0] = -27.666160, states[40]= 0.000273
Saving checkpoint... 
Iteration: 741604270, states[0] = 29.305678, states[40]= 0.034794
Saving checkpoint... 
Iteration: 752849502, states[0] = -35.988957, states[40]= 0.000240
Saving checkpoint... 
Iteration: 764118535, states[0] = 25.407021, states[40]= 0.000086
Saving checkpoint... 
Iteration: 775350507, states[0] = -40.336128, states[40]= 0.000191
Saving checkpoint... 
Iteration: 786626496, states[0] = 19.874955, states[40]= 0.000005
Saving checkpoint... 
Iteration: 797876889, states[0] = -79.918615, states[40]= 0.000002
Saving checkpoint... 
Iteration: 809129895, states[0] = 16.402308, states[40]= 0.000009
Saving checkpoint... 
Iteration: 820393817, states[0] = -84.707826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831652060, states[0] = -3.980987, states[40]= 0.000297
Saving checkpoint... 
Iteration: 842872431, states[0] = -79.953004, states[40]= 0.000002
Saving checkpoint... 
Iteration: 854096713, states[0] = 29.495103, states[40]= 0.008841
Saving checkpoint... 
Iteration: 865328572, states[0] = -22.587673, states[40]= 0.000255
Saving checkpoint... 
Iteration: 876590824, states[0] = 29.316518, states[40]= 0.034093
Saving checkpoint... 
Iteration: 887815306, states[0] = -6.759875, states[40]= 0.000323
Saving checkpoint... 
Iteration: 899047350, states[0] = -84.542764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910300533, states[0] = 6.243003, states[40]= 0.000095
Saving checkpoint... 
Iteration: 921538364, states[0] = -83.814380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932752157, states[0] = 29.361228, states[40]= 0.030681
Saving checkpoint... 
Iteration: 944009288, states[0] = -52.227660, states[40]= 0.000071
Saving checkpoint... 
Iteration: 955266199, states[0] = 25.356462, states[40]= 0.000082
Saving checkpoint... 
Iteration: 966480268, states[0] = -15.521262, states[40]= 0.000278
Saving checkpoint... 
Iteration: 977748131, states[0] = 29.424209, states[40]= 0.025717
Saving checkpoint... 
Iteration: 989007838, states[0] = -56.343706, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1000271963, states[0] = 19.781500, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1011502155, states[0] = -51.709132, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1022725662, states[0] = -84.950065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033958775, states[0] = 2.787735, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1045156310, states[0] = -39.585570, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1056366720, states[0] = -84.601029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067601682, states[0] = 17.895865, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1078773461, states[0] = 13.866179, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1089993632, states[0] = -50.802839, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1101223982, states[0] = 31.181729, states[40]= 0.292745
Saving checkpoint... 
Iteration: 1112453960, states[0] = -0.199621, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1123680636, states[0] = -82.218053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134921181, states[0] = 22.073860, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1146164585, states[0] = -64.561500, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1157427171, states[0] = 17.187910, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1168658105, states[0] = -58.485734, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1179897778, states[0] = 29.478674, states[40]= 0.007867
Saving checkpoint... 
Iteration: 1191130073, states[0] = -23.632977, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1202376397, states[0] = -84.960523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213597257, states[0] = 11.103967, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1224840886, states[0] = -83.677388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236077544, states[0] = 22.180153, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1247335744, states[0] = -82.639427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258596952, states[0] = 7.937772, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1269862855, states[0] = -84.882334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281140265, states[0] = -49.567835, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1292374938, states[0] = 29.734413, states[40]= 0.551203
Saving checkpoint... 
Iteration: 1303608890, states[0] = -9.231371, states[40]= 0.000324
Saving checkpoint... 
Iteration: 1314868413, states[0] = -84.986157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326097915, states[0] = 1.177166, states[40]= 0.000196
Saving checkpoint... 
Iteration: 1337349129, states[0] = -84.790680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348579809, states[0] = 13.872444, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1359821882, states[0] = -80.924109, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1371052763, states[0] = 27.630161, states[40]= 0.000525
Saving checkpoint... 
Iteration: 1382299297, states[0] = -52.865879, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1393519298, states[0] = -84.898836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404767986, states[0] = -12.874470, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1416006301, states[0] = -84.762461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427266927, states[0] = -14.617007, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1438486926, states[0] = -83.824879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1449715087, states[0] = 26.149925, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1460956778, states[0] = -51.095250, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1472152162, states[0] = -84.142978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483386987, states[0] = 21.714663, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1494620392, states[0] = -51.510120, states[40]= 0.000076
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.851044
 - CaMKt in component CaMK (millimolar): 0.216682
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.285664
 - nass in component intracellular_ions (millimolar): 7.286017
 - ki in component intracellular_ions (millimolar): 143.833962
 - kss in component intracellular_ions (millimolar): 143.833927
 - cansr in component intracellular_ions (millimolar): 3.332850
 - cajsr in component intracellular_ions (millimolar): 1.922412
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009953
 - hf in component INa (dimensionless): 0.584415
 - hs in component INa (dimensionless): 0.583366
 - j in component INa (dimensionless): 0.554006
 - hsp in component INa (dimensionless): 0.331887
 - jp in component INa (dimensionless): 0.512445
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.183571
 - hLp in component INaL (dimensionless): 0.074920
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999238
 - iS in component Ito (dimensionless): 0.131392
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999238
 - iSp in component Ito (dimensionless): 0.146945
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677706
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928918
 - jca in component ICaL (dimensionless): 0.911536
 - ffp in component ICaL (dimensionless): 0.998940
 - fcafp in component ICaL (dimensionless): 0.999940
 - nca in component ICaL (dimensionless): 0.041891
 - xrf in component IKr (dimensionless): 0.100359
 - xrs in component IKr (dimensionless): 0.872498
 - xs1 in component IKs (dimensionless): 0.570392
 - xs2 in component IKs (dimensionless): 0.007138
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:55:16 (16722): called boinc_finish(0)

</stderr_txt>
]]>


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