𝕏

Task 56143220

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_852_0
Workunit 26663219
Created 4 Jul 2024, 21:05:33 UTC
Sent 5 Jul 2024, 3:28:58 UTC
Report deadline 8 Jul 2024, 3:28:58 UTC
Received 5 Jul 2024, 8:54:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242053
Run time 4 hours 51 min 42 sec
CPU time 4 hours 49 min 9 sec
Validate state Valid
Credit 49.10
Device peak FLOPS 2.31 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_852.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_852_0_r1536237322_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_10000-conf_852_0_r1536237322_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.895410
     * GNaL_b in INaL: 0.005845
     * Gto_b in Ito: 0.085123
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031957
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.162885
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.185078
     * GKb_b in IKb: 0.003803
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033979
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5179331, states[0] = -69.045486, states[40]= 0.000003
Saving checkpoint... 
Iteration: 10549907, states[0] = -94.302721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15803735, states[0] = -94.272004, states[40]= 0.000000
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Iteration: 20997446, states[0] = -94.239640, states[40]= 0.000000
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Iteration: 26308519, states[0] = -94.210325, states[40]= 0.000000
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Iteration: 31655950, states[0] = -94.188118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36835273, states[0] = -94.175005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41841889, states[0] = -94.168021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47086895, states[0] = -94.160316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52176400, states[0] = -94.156590, states[40]= 0.000000
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Iteration: 57398746, states[0] = -94.153075, states[40]= 0.000000
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Iteration: 62502887, states[0] = -94.151641, states[40]= 0.000000
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Iteration: 67662012, states[0] = -94.150554, states[40]= 0.000000
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Iteration: 72643071, states[0] = -94.150967, states[40]= 0.000000
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Iteration: 77779194, states[0] = -94.150769, states[40]= 0.000000
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Iteration: 83080417, states[0] = -94.150163, states[40]= 0.000000
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Iteration: 88203535, states[0] = -94.150495, states[40]= 0.000000
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Iteration: 93286165, states[0] = -94.151011, states[40]= 0.000000
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Iteration: 98451507, states[0] = -94.151325, states[40]= 0.000000
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Iteration: 103642818, states[0] = -94.151622, states[40]= 0.000000
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Iteration: 108879177, states[0] = -94.151879, states[40]= 0.000000
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Iteration: 114070915, states[0] = -94.152225, states[40]= 0.000000
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Iteration: 119232504, states[0] = -94.152594, states[40]= 0.000000
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Iteration: 124262796, states[0] = -94.153062, states[40]= 0.000000
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Iteration: 129436332, states[0] = -94.153344, states[40]= 0.000000
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Iteration: 134877041, states[0] = -94.153428, states[40]= 0.000000
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Iteration: 140076747, states[0] = 17.282247, states[40]= 0.000005
Saving checkpoint... 
Iteration: 145367171, states[0] = -94.089310, states[40]= 0.000000
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Iteration: 150330778, states[0] = -94.030623, states[40]= 0.000000
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Iteration: 155503798, states[0] = -94.181016, states[40]= 0.000000
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Iteration: 160693311, states[0] = -94.199578, states[40]= 0.000000
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Iteration: 166028422, states[0] = -94.188697, states[40]= 0.000000
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Iteration: 171359045, states[0] = -94.177926, states[40]= 0.000000
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Iteration: 176381722, states[0] = -94.177452, states[40]= 0.000000
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Iteration: 181486113, states[0] = -94.175003, states[40]= 0.000000
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Iteration: 186779905, states[0] = -94.169450, states[40]= 0.000000
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Iteration: 191853758, states[0] = -94.168399, states[40]= 0.000000
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Iteration: 197056893, states[0] = -94.165819, states[40]= 0.000000
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Iteration: 202050547, states[0] = -94.165947, states[40]= 0.000000
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Iteration: 207338924, states[0] = -94.163131, states[40]= 0.000000
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Iteration: 212811969, states[0] = -94.160071, states[40]= 0.000000
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Iteration: 218268853, states[0] = -94.158289, states[40]= 0.000000
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Iteration: 223611428, states[0] = -94.157424, states[40]= 0.000000
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Iteration: 228780341, states[0] = -94.157105, states[40]= 0.000000
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Iteration: 234030544, states[0] = -94.156714, states[40]= 0.000000
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Iteration: 239169857, states[0] = -94.156537, states[40]= 0.000000
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Iteration: 244373968, states[0] = -94.156311, states[40]= 0.000000
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Iteration: 249523452, states[0] = -94.156170, states[40]= 0.000000
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Iteration: 254537677, states[0] = -94.156154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259752255, states[0] = -94.155978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265040443, states[0] = 26.725949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270297439, states[0] = -93.951171, states[40]= 0.000000
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Iteration: 275350987, states[0] = -94.067842, states[40]= 0.000000
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Iteration: 280617962, states[0] = -94.198834, states[40]= 0.000000
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Iteration: 285900565, states[0] = -94.194631, states[40]= 0.000000
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Iteration: 291036385, states[0] = -94.189170, states[40]= 0.000000
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Iteration: 311952580, states[0] = -94.167172, states[40]= 0.000000
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Iteration: 322306258, states[0] = -94.163339, states[40]= 0.000000
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Iteration: 327577844, states[0] = -94.161273, states[40]= 0.000000
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Iteration: 332809475, states[0] = -94.159929, states[40]= 0.000000
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Iteration: 338001838, states[0] = -94.159033, states[40]= 0.000000
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Iteration: 348599748, states[0] = -94.157174, states[40]= 0.000000
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Iteration: 353695156, states[0] = -94.156953, states[40]= 0.000000
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Iteration: 358914941, states[0] = -94.156540, states[40]= 0.000000
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Iteration: 364343547, states[0] = -94.155961, states[40]= 0.000000
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Iteration: 369509394, states[0] = -94.155778, states[40]= 0.000000
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Iteration: 374778559, states[0] = -94.155542, states[40]= 0.000000
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Iteration: 379960042, states[0] = -94.155402, states[40]= 0.000000
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Iteration: 385129203, states[0] = -18.270614, states[40]= 0.000255
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Iteration: 390221604, states[0] = -93.593656, states[40]= 0.000000
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Iteration: 395267374, states[0] = -93.844290, states[40]= 0.000000
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Iteration: 400571517, states[0] = -94.194482, states[40]= 0.000000
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Iteration: 405863106, states[0] = -94.195616, states[40]= 0.000000
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Iteration: 411355309, states[0] = -94.178152, states[40]= 0.000000
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Iteration: 416649560, states[0] = -94.171471, states[40]= 0.000000
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Iteration: 421694910, states[0] = -94.170622, states[40]= 0.000000
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Iteration: 427001628, states[0] = -94.166046, states[40]= 0.000000
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Iteration: 432183327, states[0] = -94.164001, states[40]= 0.000000
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Iteration: 437400305, states[0] = -94.162050, states[40]= 0.000000
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Iteration: 442674702, states[0] = -94.160166, states[40]= 0.000000
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Iteration: 447801989, states[0] = -94.159451, states[40]= 0.000000
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Iteration: 452829249, states[0] = -94.159292, states[40]= 0.000000
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Iteration: 458039131, states[0] = -94.158343, states[40]= 0.000000
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Iteration: 463429402, states[0] = -94.157061, states[40]= 0.000000
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Iteration: 468537298, states[0] = -94.156771, states[40]= 0.000000
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Iteration: 473649465, states[0] = -94.156501, states[40]= 0.000000
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Iteration: 479165122, states[0] = -94.155640, states[40]= 0.000000
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Iteration: 484238904, states[0] = -94.155529, states[40]= 0.000000
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Iteration: 489507567, states[0] = -94.155232, states[40]= 0.000000
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Iteration: 494773363, states[0] = -94.154997, states[40]= 0.000000
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Iteration: 499906508, states[0] = -94.154885, states[40]= 0.000000
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Iteration: 505177331, states[0] = -72.975529, states[40]= 0.000004
Saving checkpoint... 
Iteration: 510442818, states[0] = -94.156555, states[40]= 0.000000
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Iteration: 515717653, states[0] = -94.199375, states[40]= 0.000000
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Iteration: 521001685, states[0] = -94.189525, states[40]= 0.000000
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Iteration: 526132489, states[0] = -94.184565, states[40]= 0.000000
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Iteration: 536199126, states[0] = -94.182244, states[40]= 0.000000
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Iteration: 546510582, states[0] = -94.173715, states[40]= 0.000000
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Iteration: 551833528, states[0] = -94.167760, states[40]= 0.000000
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Iteration: 562489820, states[0] = -94.160804, states[40]= 0.000000
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Iteration: 567831548, states[0] = -94.158750, states[40]= 0.000000
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Iteration: 572952844, states[0] = -94.158168, states[40]= 0.000000
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Iteration: 578220799, states[0] = -94.157139, states[40]= 0.000000
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Iteration: 598784661, states[0] = -94.155661, states[40]= 0.000000
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Iteration: 619602796, states[0] = -94.154549, states[40]= 0.000000
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Iteration: 625207398, states[0] = -93.484921, states[40]= 0.000000
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Iteration: 630460439, states[0] = -94.164950, states[40]= 0.000000
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Iteration: 635727351, states[0] = -94.198687, states[40]= 0.000000
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Iteration: 641068439, states[0] = -94.186380, states[40]= 0.000000
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Iteration: 672750158, states[0] = -94.158683, states[40]= 0.000000
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Iteration: 683066682, states[0] = -94.157197, states[40]= 0.000000
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Iteration: 725105027, states[0] = 2.660832, states[40]= 0.000122
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Iteration: 730189785, states[0] = -90.827359, states[40]= 0.000000
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Iteration: 735395327, states[0] = -94.120469, states[40]= 0.000000
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Iteration: 751112854, states[0] = -94.184230, states[40]= 0.000000
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Iteration: 808130961, states[0] = -94.156382, states[40]= 0.000000
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Iteration: 813145807, states[0] = -94.156306, states[40]= 0.000000
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Iteration: 849674585, states[0] = -94.153428, states[40]= 0.000000
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Iteration: 901116095, states[0] = -94.183421, states[40]= 0.000000
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Iteration: 963173884, states[0] = -94.155515, states[40]= 0.000000
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Iteration: 973481178, states[0] = -94.154572, states[40]= 0.000000
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Iteration: 978563042, states[0] = -94.154355, states[40]= 0.000000
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Iteration: 994453502, states[0] = -94.152946, states[40]= 0.000000
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Iteration: 1000012937, states[0] = 22.347282, states[40]= 0.000000
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Iteration: 1005060766, states[0] = 22.979208, states[40]= 0.000000
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Iteration: 1010142957, states[0] = -32.650394, states[40]= 0.000413
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Iteration: 1015524413, states[0] = -94.183970, states[40]= 0.000000
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Iteration: 1025838642, states[0] = -94.193692, states[40]= 0.000000
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Iteration: 1031122000, states[0] = -94.182609, states[40]= 0.000000
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Iteration: 1036102622, states[0] = -94.183288, states[40]= 0.000000
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Iteration: 1041181696, states[0] = -94.180493, states[40]= 0.000000
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Iteration: 1046328000, states[0] = -94.175976, states[40]= 0.000000
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Iteration: 1088837581, states[0] = -94.153301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094170099, states[0] = -94.152791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099283915, states[0] = -94.152634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104532996, states[0] = -94.152365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109980563, states[0] = -94.152019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115182991, states[0] = -82.023250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1120269399, states[0] = -93.849305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125247262, states[0] = -93.745407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130608508, states[0] = -94.194424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135987692, states[0] = -94.187249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141562424, states[0] = -94.169849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146793275, states[0] = -94.165631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152069664, states[0] = -94.161891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157083476, states[0] = -94.161712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162297644, states[0] = -94.159555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167595385, states[0] = -94.157298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172638708, states[0] = -94.157006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177732156, states[0] = -94.156445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182883094, states[0] = -94.155660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188046174, states[0] = -94.154941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193421574, states[0] = -94.153707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198508799, states[0] = -94.153464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203645314, states[0] = -94.153134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208627506, states[0] = -94.153149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213635404, states[0] = -94.153109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218700322, states[0] = -94.152953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223742006, states[0] = -94.152849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228893012, states[0] = -94.152561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234106281, states[0] = -94.152225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239215045, states[0] = -94.152066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244433644, states[0] = -94.151809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249463620, states[0] = -94.151757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254698612, states[0] = -94.151536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260064627, states[0] = 21.778071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265326839, states[0] = -94.019596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270551980, states[0] = -94.187856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275835569, states[0] = -94.192654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280813883, states[0] = -94.193406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285772823, states[0] = -94.194678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290946664, states[0] = -94.188191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295931530, states[0] = -94.188782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300952213, states[0] = -94.187920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306319790, states[0] = -94.175007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311408046, states[0] = -94.172619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316566938, states[0] = -94.168947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321787268, states[0] = -94.164917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326955754, states[0] = -94.162470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332151243, states[0] = -94.160171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337434868, states[0] = -94.157625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342643186, states[0] = -94.156193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347604782, states[0] = -94.156406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352655986, states[0] = -94.156070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357863982, states[0] = -94.154941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363198081, states[0] = -94.153584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368333319, states[0] = -94.153141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373572343, states[0] = -94.152507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378648506, states[0] = -94.152318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383905448, states[0] = -94.151824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389220544, states[0] = -94.151365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394245731, states[0] = -94.151313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399658096, states[0] = -94.150897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404652485, states[0] = -94.150878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409623589, states[0] = -94.150878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415020503, states[0] = 24.883325, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1420158211, states[0] = -49.948905, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1425491464, states[0] = -94.173290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430704621, states[0] = -94.195286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435915016, states[0] = -94.188807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441469615, states[0] = -94.170518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446596077, states[0] = -94.167753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451813216, states[0] = -94.163911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456780033, states[0] = -94.164409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461750187, states[0] = -94.164872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466836531, states[0] = -94.163488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471813701, states[0] = -94.163811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476880217, states[0] = -94.162805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481892471, states[0] = -94.162609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486869684, states[0] = -94.162909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492000169, states[0] = -94.161145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497462304, states[0] = -94.156681, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.026191
 - CaMKt in component CaMK (millimolar): 0.000980
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.988196
 - nass in component intracellular_ions (millimolar): 6.988327
 - ki in component intracellular_ions (millimolar): 144.758076
 - kss in component intracellular_ions (millimolar): 144.758066
 - cansr in component intracellular_ions (millimolar): 2.347526
 - cajsr in component intracellular_ions (millimolar): 2.347671
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003953
 - hf in component INa (dimensionless): 0.863955
 - hs in component INa (dimensionless): 0.863955
 - j in component INa (dimensionless): 0.863956
 - hsp in component INa (dimensionless): 0.696314
 - jp in component INa (dimensionless): 0.863956
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.705460
 - hLp in component INaL (dimensionless): 0.511364
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999848
 - iS in component Ito (dimensionless): 0.999848
 - ap in component Ito (dimensionless): 0.000337
 - iFp in component Ito (dimensionless): 0.999848
 - iSp in component Ito (dimensionless): 0.999848
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005141
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002077
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997558
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:54:06 (33619): called boinc_finish(0)

</stderr_txt>
]]>


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