𝕏

Task 56141943

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_951_1
Workunit 26662580
Created 4 Jul 2024, 21:04:57 UTC
Sent 5 Jul 2024, 3:13:42 UTC
Report deadline 8 Jul 2024, 3:13:42 UTC
Received 8 Jul 2024, 5:31:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 13 sec
CPU time 38 min 4 sec
Validate state Valid
Credit 42.29
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.64 MB
Peak swap size 391.88 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_951.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_951_1_r1245469628_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_951_1_r1245469628_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.754436
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.084550
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031951
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163139
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.257521
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032585
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10179560, states[0] = -94.530958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19676298, states[0] = -94.191382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29527989, states[0] = 25.031264, states[40]= 0.001643
Saving checkpoint... 
Iteration: 38925884, states[0] = -94.922774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47950637, states[0] = -94.928563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58110082, states[0] = -22.686840, states[40]= 0.001212
Saving checkpoint... 
Iteration: 69942891, states[0] = -94.921822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79431433, states[0] = -94.916511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88390088, states[0] = -94.895069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98205491, states[0] = -94.543743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106825015, states[0] = -94.837221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116479279, states[0] = -94.929922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127539925, states[0] = 21.253416, states[40]= 0.002051
Saving checkpoint... 
Iteration: 136947443, states[0] = -94.920118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147051753, states[0] = 16.760714, states[40]= 0.002910
Saving checkpoint... 
Iteration: 157795455, states[0] = -94.794292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166199037, states[0] = -94.513555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176343197, states[0] = -94.855871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185469995, states[0] = -94.926487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194835230, states[0] = -94.847469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203864046, states[0] = -94.874339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214928335, states[0] = -94.912131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225826010, states[0] = -94.836826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236396204, states[0] = -94.896162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247600542, states[0] = -13.049326, states[40]= 0.002048
Saving checkpoint... 
Iteration: 256924341, states[0] = -94.910227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266622667, states[0] = -34.515684, states[40]= 0.000678
Saving checkpoint... 
Iteration: 276398532, states[0] = -94.897315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285651385, states[0] = -64.704113, states[40]= 0.000009
Saving checkpoint... 
Iteration: 295700928, states[0] = -94.521471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305679936, states[0] = -94.227170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316340365, states[0] = -94.852305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325550654, states[0] = 17.201523, states[40]= 0.002823
Saving checkpoint... 
Iteration: 334489465, states[0] = -94.930576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343481798, states[0] = -94.928768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353222751, states[0] = -94.609586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362689146, states[0] = -94.455916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373334486, states[0] = -94.845859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384638507, states[0] = -50.497675, states[40]= 0.000085
Saving checkpoint... 
Iteration: 395478335, states[0] = -94.927709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405548510, states[0] = 18.040649, states[40]= 0.002655
Saving checkpoint... 
Iteration: 415483225, states[0] = -94.928818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425005634, states[0] = 29.803520, states[40]= 0.210140
Saving checkpoint... 
Iteration: 434568037, states[0] = 9.695713, states[40]= 0.004178
Saving checkpoint... 
Iteration: 443621813, states[0] = -33.691432, states[40]= 0.000734
Saving checkpoint... 
Iteration: 453007706, states[0] = 28.131095, states[40]= 0.105487
Saving checkpoint... 
Iteration: 462479401, states[0] = -94.927705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473584705, states[0] = 0.336335, states[40]= 0.004541
Saving checkpoint... 
Iteration: 484277370, states[0] = -94.759692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494444456, states[0] = -94.917172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504531750, states[0] = 24.055814, states[40]= 0.001640
Saving checkpoint... 
Iteration: 513201560, states[0] = -94.523412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523840927, states[0] = -94.852040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534552943, states[0] = 16.289608, states[40]= 0.003008
Saving checkpoint... 
Iteration: 545294956, states[0] = -94.791649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556095418, states[0] = -8.147547, states[40]= 0.003083
Saving checkpoint... 
Iteration: 567046369, states[0] = 18.864825, states[40]= 0.002493
Saving checkpoint... 
Iteration: 576786413, states[0] = -94.776649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585365108, states[0] = -94.873587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595337110, states[0] = -94.847784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605466723, states[0] = -94.923783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616153038, states[0] = -66.716519, states[40]= 0.000006
Saving checkpoint... 
Iteration: 626705893, states[0] = -94.541847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635504950, states[0] = 31.006088, states[40]= 0.262491
Saving checkpoint... 
Iteration: 646514211, states[0] = 27.648599, states[40]= 0.012485
Saving checkpoint... 
Iteration: 656176381, states[0] = -93.831293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665173069, states[0] = -92.884783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674145742, states[0] = -58.270867, states[40]= 0.000025
Saving checkpoint... 
Iteration: 685468252, states[0] = -94.923889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694076115, states[0] = 5.547914, states[40]= 0.004578
Saving checkpoint... 
Iteration: 703619984, states[0] = -31.933431, states[40]= 0.000855
Saving checkpoint... 
Iteration: 714022285, states[0] = 26.612098, states[40]= 0.001980
Saving checkpoint... 
Iteration: 724112522, states[0] = -24.792736, states[40]= 0.001184
Saving checkpoint... 
Iteration: 734072320, states[0] = 7.568210, states[40]= 0.004424
Saving checkpoint... 
Iteration: 742666183, states[0] = -86.394916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752074806, states[0] = 6.260781, states[40]= 0.004533
Saving checkpoint... 
Iteration: 762208318, states[0] = -94.551527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771923391, states[0] = -94.907728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780931858, states[0] = -94.911255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790478770, states[0] = -94.926231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801327887, states[0] = -94.836686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810018212, states[0] = 27.310631, states[40]= 0.004060
Saving checkpoint... 
Iteration: 820262890, states[0] = -94.726721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828762829, states[0] = -94.726542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836983876, states[0] = -94.927279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845089107, states[0] = -2.824906, states[40]= 0.004170
Saving checkpoint... 
Iteration: 856324571, states[0] = -94.832522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866653658, states[0] = -67.492675, states[40]= 0.000005
Saving checkpoint... 
Iteration: 875049352, states[0] = 17.713476, states[40]= 0.002721
Saving checkpoint... 
Iteration: 883807649, states[0] = -94.809984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893232281, states[0] = -94.640453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901402465, states[0] = -94.896971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910397620, states[0] = -94.894240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919950555, states[0] = -94.917559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930439428, states[0] = -94.913591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941559065, states[0] = 13.751772, states[40]= 0.003510
Saving checkpoint... 
Iteration: 951405738, states[0] = -94.898518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962295752, states[0] = -94.791280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971935878, states[0] = -94.912075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981192825, states[0] = -94.478524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990770943, states[0] = -94.744232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998293193, states[0] = -94.786860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007031809, states[0] = 24.037716, states[40]= 0.001642
Saving checkpoint... 
Iteration: 1016958955, states[0] = -94.919849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026511397, states[0] = 27.698683, states[40]= 0.030841
Saving checkpoint... 
Iteration: 1035797579, states[0] = -94.793962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046240754, states[0] = -94.666570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056793124, states[0] = -94.786507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066294809, states[0] = -94.789298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076602736, states[0] = -15.216582, states[40]= 0.001706
Saving checkpoint... 
Iteration: 1086472047, states[0] = -94.923311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096234684, states[0] = -94.647459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106907004, states[0] = -94.898553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117644409, states[0] = -56.811640, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1128348223, states[0] = -94.856764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138601142, states[0] = -13.637219, states[40]= 0.001946
Saving checkpoint... 
Iteration: 1148562985, states[0] = 12.037591, states[40]= 0.003819
Saving checkpoint... 
Iteration: 1158622580, states[0] = -34.427815, states[40]= 0.000684
Saving checkpoint... 
Iteration: 1167427892, states[0] = -94.908071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176686293, states[0] = -94.422505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185101590, states[0] = -14.080085, states[40]= 0.001873
Saving checkpoint... 
Iteration: 1195248576, states[0] = -94.688562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203902593, states[0] = -94.895824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214436633, states[0] = -94.911392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223788820, states[0] = -94.778364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233116345, states[0] = -28.449348, states[40]= 0.001065
Saving checkpoint... 
Iteration: 1241653125, states[0] = -66.819826, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1252108271, states[0] = -20.679568, states[40]= 0.001264
Saving checkpoint... 
Iteration: 1262785610, states[0] = -94.772404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271144934, states[0] = -57.382566, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1281745296, states[0] = -94.678969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291762898, states[0] = -94.724828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301216179, states[0] = -94.580992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310638552, states[0] = -50.540522, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1320366828, states[0] = -94.871981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330398253, states[0] = -94.892910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340715644, states[0] = -94.578748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352604174, states[0] = -16.642798, states[40]= 0.001533
Saving checkpoint... 
Iteration: 1362420380, states[0] = -94.904012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371248033, states[0] = -94.686340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380824384, states[0] = -94.830180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387531308, states[0] = 24.196474, states[40]= 0.001625
Saving checkpoint... 
Iteration: 1397876119, states[0] = -94.878581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407834819, states[0] = -94.842050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417120398, states[0] = -32.327894, states[40]= 0.000828
Saving checkpoint... 
Iteration: 1427457090, states[0] = -94.917625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437443335, states[0] = -94.912983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447481314, states[0] = -94.924216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456030066, states[0] = 24.580289, states[40]= 0.001588
Saving checkpoint... 
Iteration: 1465636239, states[0] = -48.107593, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1474268600, states[0] = -94.737143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484157985, states[0] = -73.360031, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1496050306, states[0] = 17.340263, states[40]= 0.002796
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.803980
 - CaMKt in component CaMK (millimolar): 0.012785
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.741844
 - nass in component intracellular_ions (millimolar): 6.741942
 - ki in component intracellular_ions (millimolar): 145.137420
 - kss in component intracellular_ions (millimolar): 145.137399
 - cansr in component intracellular_ions (millimolar): 1.673357
 - cajsr in component intracellular_ions (millimolar): 1.631731
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003654
 - hf in component INa (dimensionless): 0.878292
 - hs in component INa (dimensionless): 0.878284
 - j in component INa (dimensionless): 0.878233
 - hsp in component INa (dimensionless): 0.722598
 - jp in component INa (dimensionless): 0.878198
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704866
 - hLp in component INaL (dimensionless): 0.442294
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.612041
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.683008
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916467
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999836
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003098
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.364849
 - xs1 in component IKs (dimensionless): 0.266643
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997363
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:30:52 (27707): called boinc_finish(0)

</stderr_txt>
]]>


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