𝕏

Task 56141739

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Kr_70-conf_750_1
Workunit 26662478
Created 4 Jul 2024, 21:04:51 UTC
Sent 5 Jul 2024, 3:13:42 UTC
Report deadline 8 Jul 2024, 3:13:42 UTC
Received 8 Jul 2024, 4:37:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 40 min 56 sec
CPU time 37 min 59 sec
Validate state Valid
Credit 43.14
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.55 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Kr_70-conf_750.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Kr_70-conf_750_1_r1063561785_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Kr_70-conf_750_1_r1063561785_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.469502
     * GNaL_b in INaL: 0.005817
     * Gto_b in Ito: 0.084128
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009549
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.164163
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.642048
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032043
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10936651, states[0] = -94.909722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20739596, states[0] = -52.457586, states[40]= 0.000155
Saving checkpoint... 
Iteration: 32608028, states[0] = 2.844871, states[40]= 0.005122
Saving checkpoint... 
Iteration: 41482613, states[0] = -94.829646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50331913, states[0] = -94.686954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61715796, states[0] = -36.116881, states[40]= 0.001785
Saving checkpoint... 
Iteration: 72260370, states[0] = -54.492844, states[40]= 0.000113
Saving checkpoint... 
Iteration: 81772135, states[0] = -60.413449, states[40]= 0.000040
Saving checkpoint... 
Iteration: 90541851, states[0] = 25.637362, states[40]= 0.003119
Saving checkpoint... 
Iteration: 99890473, states[0] = -94.733905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109378826, states[0] = -94.719504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118814498, states[0] = -94.451933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128426049, states[0] = -94.756745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138964255, states[0] = -94.776691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149262313, states[0] = -53.038165, states[40]= 0.000139
Saving checkpoint... 
Iteration: 159429108, states[0] = -94.755662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169516752, states[0] = 31.019999, states[40]= 0.007165
Saving checkpoint... 
Iteration: 178974043, states[0] = -94.778143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188533225, states[0] = 28.194824, states[40]= 0.002884
Saving checkpoint... 
Iteration: 197006515, states[0] = 31.485653, states[40]= 0.139005
Saving checkpoint... 
Iteration: 205730840, states[0] = -39.421728, states[40]= 0.001121
Saving checkpoint... 
Iteration: 215001325, states[0] = 49.300278, states[40]= 0.194012
Saving checkpoint... 
Iteration: 224180468, states[0] = -23.295914, states[40]= 0.005108
Saving checkpoint... 
Iteration: 235046320, states[0] = 24.542314, states[40]= 0.003450
Saving checkpoint... 
Iteration: 245950943, states[0] = -94.765861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255591820, states[0] = 10.242985, states[40]= 0.005163
Saving checkpoint... 
Iteration: 264824593, states[0] = -94.616641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274103761, states[0] = 6.035687, states[40]= 0.005160
Saving checkpoint... 
Iteration: 283940286, states[0] = -94.759677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293887011, states[0] = -94.718335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304557045, states[0] = 21.413820, states[40]= 0.004059
Saving checkpoint... 
Iteration: 315935497, states[0] = -94.756666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326313800, states[0] = -94.228302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335841261, states[0] = -94.659376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345597219, states[0] = 8.365418, states[40]= 0.005185
Saving checkpoint... 
Iteration: 355300851, states[0] = -85.025056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365709953, states[0] = -32.086813, states[40]= 0.002779
Saving checkpoint... 
Iteration: 374854105, states[0] = -94.678609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385190540, states[0] = -26.176673, states[40]= 0.004616
Saving checkpoint... 
Iteration: 393706376, states[0] = -30.944352, states[40]= 0.003137
Saving checkpoint... 
Iteration: 403864770, states[0] = -94.692788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414311763, states[0] = -93.908830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424534554, states[0] = 27.862603, states[40]= 0.002933
Saving checkpoint... 
Iteration: 435383519, states[0] = -94.714305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444864636, states[0] = -94.692514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455451325, states[0] = -94.765221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465912983, states[0] = -94.740752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476493288, states[0] = -94.783021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486622476, states[0] = -0.978601, states[40]= 0.004590
Saving checkpoint... 
Iteration: 495502539, states[0] = 42.750970, states[40]= 0.347154
Saving checkpoint... 
Iteration: 505570963, states[0] = 17.170179, states[40]= 0.004715
Saving checkpoint... 
Iteration: 514911630, states[0] = -94.739583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525225238, states[0] = -37.292510, states[40]= 0.001484
Saving checkpoint... 
Iteration: 533991030, states[0] = -94.782101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544357833, states[0] = -94.683342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554419585, states[0] = -94.745455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564251653, states[0] = -47.751636, states[40]= 0.000329
Saving checkpoint... 
Iteration: 573590785, states[0] = 10.606212, states[40]= 0.005154
Saving checkpoint... 
Iteration: 583113999, states[0] = 2.284941, states[40]= 0.004966
Saving checkpoint... 
Iteration: 594230994, states[0] = -39.403206, states[40]= 0.001122
Saving checkpoint... 
Iteration: 605153175, states[0] = -14.070220, states[40]= 0.002697
Saving checkpoint... 
Iteration: 614889479, states[0] = -94.719904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624984912, states[0] = -94.779674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634646186, states[0] = -11.079053, states[40]= 0.002722
Saving checkpoint... 
Iteration: 644808953, states[0] = -93.049336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654804209, states[0] = -89.485840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664349410, states[0] = -94.671118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673931381, states[0] = -94.753167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684048989, states[0] = 23.774919, states[40]= 0.003601
Saving checkpoint... 
Iteration: 693680034, states[0] = -23.142884, states[40]= 0.005117
Saving checkpoint... 
Iteration: 704124195, states[0] = -1.662913, states[40]= 0.004483
Saving checkpoint... 
Iteration: 714428138, states[0] = -94.750965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723522171, states[0] = 30.564975, states[40]= 0.003396
Saving checkpoint... 
Iteration: 734335872, states[0] = -94.649190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742782346, states[0] = -64.022349, states[40]= 0.000021
Saving checkpoint... 
Iteration: 752253283, states[0] = -48.465261, states[40]= 0.000294
Saving checkpoint... 
Iteration: 760509490, states[0] = 30.749767, states[40]= 0.054190
Saving checkpoint... 
Iteration: 770603240, states[0] = 6.227671, states[40]= 0.005164
Saving checkpoint... 
Iteration: 780835203, states[0] = -94.647847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789408920, states[0] = -94.736775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797485480, states[0] = -94.779470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807737679, states[0] = -41.967788, states[40]= 0.000786
Saving checkpoint... 
Iteration: 816117618, states[0] = 0.912971, states[40]= 0.004834
Saving checkpoint... 
Iteration: 825886266, states[0] = -94.716188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835385366, states[0] = -94.715247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846597472, states[0] = 8.277558, states[40]= 0.005185
Saving checkpoint... 
Iteration: 856796460, states[0] = -78.433291, states[40]= 0.000002
Saving checkpoint... 
Iteration: 867392953, states[0] = -94.722645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878132956, states[0] = -5.290274, states[40]= 0.003783
Saving checkpoint... 
Iteration: 887522313, states[0] = 30.544553, states[40]= 0.003363
Saving checkpoint... 
Iteration: 898274243, states[0] = -58.808049, states[40]= 0.000051
Saving checkpoint... 
Iteration: 907990411, states[0] = -94.780984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917043980, states[0] = 25.224335, states[40]= 0.003330
Saving checkpoint... 
Iteration: 923247068, states[0] = -45.788056, states[40]= 0.000447
Saving checkpoint... 
Iteration: 934322722, states[0] = -94.599608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944991888, states[0] = -94.781411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955609499, states[0] = 3.956113, states[40]= 0.005079
Saving checkpoint... 
Iteration: 966015885, states[0] = 31.056845, states[40]= 0.008733
Saving checkpoint... 
Iteration: 974944938, states[0] = -94.760527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984694203, states[0] = -27.244305, states[40]= 0.004322
Saving checkpoint... 
Iteration: 994054592, states[0] = 22.138702, states[40]= 0.003921
Saving checkpoint... 
Iteration: 1004961531, states[0] = -94.768955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014236072, states[0] = -41.339303, states[40]= 0.000859
Saving checkpoint... 
Iteration: 1024820692, states[0] = -94.573223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035281513, states[0] = -63.423366, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1045862882, states[0] = -94.688815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056065885, states[0] = 18.752897, states[40]= 0.004508
Saving checkpoint... 
Iteration: 1065568385, states[0] = 17.979228, states[40]= 0.004615
Saving checkpoint... 
Iteration: 1074130229, states[0] = -4.136058, states[40]= 0.004025
Saving checkpoint... 
Iteration: 1084043557, states[0] = 25.346097, states[40]= 0.003308
Saving checkpoint... 
Iteration: 1095230560, states[0] = -39.240094, states[40]= 0.001147
Saving checkpoint... 
Iteration: 1105911531, states[0] = -94.738081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115972071, states[0] = -94.773394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124705439, states[0] = -30.648140, states[40]= 0.003232
Saving checkpoint... 
Iteration: 1134381346, states[0] = -94.710320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143526410, states[0] = 29.819464, states[40]= 0.002890
Saving checkpoint... 
Iteration: 1151804791, states[0] = -90.102658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163255466, states[0] = -49.434890, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1174957640, states[0] = -94.766678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186312332, states[0] = -94.012843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194397921, states[0] = -94.726443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204556932, states[0] = 21.449143, states[40]= 0.004053
Saving checkpoint... 
Iteration: 1212295602, states[0] = -77.230753, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1221454033, states[0] = -94.764769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230795050, states[0] = -76.484797, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1240205546, states[0] = -30.681536, states[40]= 0.003221
Saving checkpoint... 
Iteration: 1250655449, states[0] = -14.996124, states[40]= 0.002840
Saving checkpoint... 
Iteration: 1259339776, states[0] = -94.654665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268928144, states[0] = -94.749634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279400275, states[0] = -94.728331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288720457, states[0] = -35.602687, states[40]= 0.001838
Saving checkpoint... 
Iteration: 1298792294, states[0] = -73.062517, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1308187229, states[0] = -25.218231, states[40]= 0.004835
Saving checkpoint... 
Iteration: 1317313327, states[0] = -94.164358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328274172, states[0] = -58.765351, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1337893915, states[0] = -94.722417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348645068, states[0] = -10.587240, states[40]= 0.002778
Saving checkpoint... 
Iteration: 1358408164, states[0] = -94.734794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368213680, states[0] = -33.303561, states[40]= 0.002423
Saving checkpoint... 
Iteration: 1376262612, states[0] = -52.744206, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1386329598, states[0] = -94.634054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395204608, states[0] = -30.388015, states[40]= 0.003316
Saving checkpoint... 
Iteration: 1403960111, states[0] = -94.767322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415544622, states[0] = 25.039791, states[40]= 0.003363
Saving checkpoint... 
Iteration: 1426723435, states[0] = -36.647533, states[40]= 0.001612
Saving checkpoint... 
Iteration: 1438456938, states[0] = -94.765700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447724189, states[0] = -36.915595, states[40]= 0.001557
Saving checkpoint... 
Iteration: 1457986714, states[0] = -94.778336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468166444, states[0] = -18.998939, states[40]= 0.004353
Saving checkpoint... 
Iteration: 1478035645, states[0] = 27.570215, states[40]= 0.002968
Saving checkpoint... 
Iteration: 1487070346, states[0] = 17.365454, states[40]= 0.004692
Saving checkpoint... 
Iteration: 1497111565, states[0] = 3.194020, states[40]= 0.005033
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.658655
 - CaMKt in component CaMK (millimolar): 0.015393
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.265479
 - nass in component intracellular_ions (millimolar): 6.265557
 - ki in component intracellular_ions (millimolar): 145.649221
 - kss in component intracellular_ions (millimolar): 145.649212
 - cansr in component intracellular_ions (millimolar): 1.566658
 - cajsr in component intracellular_ions (millimolar): 1.497789
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003708
 - hf in component INa (dimensionless): 0.875716
 - hs in component INa (dimensionless): 0.875703
 - j in component INa (dimensionless): 0.875619
 - hsp in component INa (dimensionless): 0.717757
 - jp in component INa (dimensionless): 0.875500
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.629627
 - hLp in component INaL (dimensionless): 0.317650
 - a in component Ito (dimensionless): 0.000634
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.465165
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.517274
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.848009
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.998997
 - jca in component ICaL (dimensionless): 0.999827
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002614
 - xrf in component IKr (dimensionless): 0.000007
 - xrs in component IKr (dimensionless): 0.527794
 - xs1 in component IKs (dimensionless): 0.367398
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997401
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:37:41 (26919): called boinc_finish(0)

</stderr_txt>
]]>


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