𝕏

Task 56140900

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_850_0
Workunit 26662059
Created 4 Jul 2024, 21:04:31 UTC
Sent 5 Jul 2024, 3:13:42 UTC
Report deadline 8 Jul 2024, 3:13:42 UTC
Received 8 Jul 2024, 4:41:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 1 sec
CPU time 38 min 3 sec
Validate state Valid
Credit 43.91
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.73 MB
Peak swap size 391.88 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_850.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_850_0_r2116388508_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_850_0_r2116388508_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.033266
     * GNaL_b in INaL: 0.005839
     * Gto_b in Ito: 0.085001
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031888
     * GKs_b in IKs: 0.001922
     * GK1_b in IK1: 0.163458
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.652299
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032388
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10969440, states[0] = -94.804665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21457557, states[0] = -94.712283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32052520, states[0] = 18.263428, states[40]= 0.002787
Saving checkpoint... 
Iteration: 43434796, states[0] = -94.653890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51983240, states[0] = -94.691568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60812469, states[0] = -94.688942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70371855, states[0] = -94.591026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79738999, states[0] = -94.680851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90390212, states[0] = -94.600218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100022183, states[0] = 26.531305, states[40]= 0.002127
Saving checkpoint... 
Iteration: 108214821, states[0] = -94.235086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117909121, states[0] = -94.671735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128843891, states[0] = -94.671937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140028740, states[0] = 25.492524, states[40]= 0.001649
Saving checkpoint... 
Iteration: 150159020, states[0] = -54.025618, states[40]= 0.000051
Saving checkpoint... 
Iteration: 158816994, states[0] = -94.670571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168887922, states[0] = -94.669083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179346237, states[0] = -94.549937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188794023, states[0] = -94.669963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200332556, states[0] = -94.532196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211447296, states[0] = -94.626139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222452111, states[0] = -94.628174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233303438, states[0] = -94.485985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243742070, states[0] = -94.669348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252892954, states[0] = -94.667891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262139053, states[0] = -35.615528, states[40]= 0.000687
Saving checkpoint... 
Iteration: 272162718, states[0] = -57.487921, states[40]= 0.000029
Saving checkpoint... 
Iteration: 282268525, states[0] = -94.409511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291986595, states[0] = -94.665486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302609041, states[0] = -94.663333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311303195, states[0] = -94.485231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320396250, states[0] = -94.595900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329974602, states[0] = -94.665703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340801834, states[0] = -94.669023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351202437, states[0] = -94.093278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361424049, states[0] = -94.613734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370301035, states[0] = -94.481120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380385583, states[0] = -94.587548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390275163, states[0] = -94.425909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400552255, states[0] = -94.655857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411883254, states[0] = -94.667684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423593462, states[0] = -94.661495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434328498, states[0] = -94.525687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445434708, states[0] = -94.619298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456241546, states[0] = -94.329208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466040904, states[0] = 22.478803, states[40]= 0.002067
Saving checkpoint... 
Iteration: 476167605, states[0] = -62.395349, states[40]= 0.000012
Saving checkpoint... 
Iteration: 486428028, states[0] = -94.615699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496286967, states[0] = -94.452687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506368178, states[0] = -94.571957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515144188, states[0] = -40.116870, states[40]= 0.000395
Saving checkpoint... 
Iteration: 524574797, states[0] = -94.659026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534738349, states[0] = -94.668629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543437865, states[0] = -94.620705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551934239, states[0] = -94.666287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561027475, states[0] = 25.762002, states[40]= 0.001662
Saving checkpoint... 
Iteration: 570941029, states[0] = -94.666087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581346317, states[0] = -94.548492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591187908, states[0] = -89.161546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601497818, states[0] = -94.643408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611575351, states[0] = -94.658939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622501198, states[0] = -94.644314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632107392, states[0] = -8.438084, states[40]= 0.002861
Saving checkpoint... 
Iteration: 640313083, states[0] = -94.501745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649575875, states[0] = -94.658938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659668743, states[0] = -94.666622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669709663, states[0] = -94.667927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679790073, states[0] = -94.668458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690315462, states[0] = -94.505529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699168999, states[0] = -63.861408, states[40]= 0.000010
Saving checkpoint... 
Iteration: 710110712, states[0] = -11.234467, states[40]= 0.002272
Saving checkpoint... 
Iteration: 717804826, states[0] = -94.668287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727428781, states[0] = -94.615658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736006990, states[0] = 27.172965, states[40]= 0.131413
Saving checkpoint... 
Iteration: 746938961, states[0] = -94.665810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756422912, states[0] = -94.612346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765804894, states[0] = -94.668197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774569205, states[0] = -94.657788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783294644, states[0] = -94.468032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793740183, states[0] = -94.668166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803083025, states[0] = 6.849194, states[40]= 0.004469
Saving checkpoint... 
Iteration: 812930241, states[0] = -94.665898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822887752, states[0] = -94.666827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833821797, states[0] = -94.667899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845051407, states[0] = 19.286367, states[40]= 0.002683
Saving checkpoint... 
Iteration: 855138581, states[0] = -35.200598, states[40]= 0.000719
Saving checkpoint... 
Iteration: 863870282, states[0] = -94.667094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873246884, states[0] = -94.345861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881587383, states[0] = -94.659948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891205496, states[0] = -94.157676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900088957, states[0] = 3.827191, states[40]= 0.004543
Saving checkpoint... 
Iteration: 910305310, states[0] = -94.487899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922053672, states[0] = 18.548523, states[40]= 0.002833
Saving checkpoint... 
Iteration: 932849773, states[0] = -94.667324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941398697, states[0] = -94.596496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951051254, states[0] = 19.335635, states[40]= 0.002673
Saving checkpoint... 
Iteration: 959749370, states[0] = -94.667929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969138966, states[0] = -35.533617, states[40]= 0.000693
Saving checkpoint... 
Iteration: 980022727, states[0] = 26.518947, states[40]= 0.002038
Saving checkpoint... 
Iteration: 991106369, states[0] = -7.606056, states[40]= 0.003045
Saving checkpoint... 
Iteration: 999930627, states[0] = -94.665541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010076641, states[0] = 9.802690, states[40]= 0.004243
Saving checkpoint... 
Iteration: 1020071425, states[0] = 12.023541, states[40]= 0.003982
Saving checkpoint... 
Iteration: 1029264559, states[0] = -94.397561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038683002, states[0] = -94.666484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047370227, states[0] = -94.572890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056735925, states[0] = -94.667633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067275484, states[0] = -94.425409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078715450, states[0] = -94.667286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088414533, states[0] = -94.606756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099275148, states[0] = -94.424535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108926414, states[0] = -94.665438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119609409, states[0] = -94.661818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128316474, states[0] = -94.506330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136856199, states[0] = -94.666838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146440592, states[0] = -94.620918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156830355, states[0] = -94.667192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167346802, states[0] = -94.547970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175876693, states[0] = -94.666392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185491180, states[0] = -94.640375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194924142, states[0] = -94.665332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204191553, states[0] = -92.097556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214352275, states[0] = -94.554166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224690887, states[0] = -94.666400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234838255, states[0] = -94.666938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244980758, states[0] = -94.663827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253589566, states[0] = -94.659511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263389416, states[0] = -94.588949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272017455, states[0] = 26.946741, states[40]= 0.005047
Saving checkpoint... 
Iteration: 1279097881, states[0] = -1.426707, states[40]= 0.004203
Saving checkpoint... 
Iteration: 1287283609, states[0] = -94.443851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297849066, states[0] = -94.666656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307277197, states[0] = -94.429063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317605141, states[0] = -94.661044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327777992, states[0] = -94.667298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337129941, states[0] = -27.823579, states[40]= 0.001292
Saving checkpoint... 
Iteration: 1346117040, states[0] = -16.773225, states[40]= 0.001489
Saving checkpoint... 
Iteration: 1355563461, states[0] = -94.655866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365060884, states[0] = 16.070264, states[40]= 0.003323
Saving checkpoint... 
Iteration: 1374927263, states[0] = -94.664923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385952761, states[0] = -94.664281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396647857, states[0] = -94.664183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407627890, states[0] = -94.662831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419288367, states[0] = -94.453943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429855690, states[0] = -94.666302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438018191, states[0] = 26.918776, states[40]= 0.004232
Saving checkpoint... 
Iteration: 1446738281, states[0] = -94.666933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455651959, states[0] = -94.664307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464659637, states[0] = -94.664696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476206176, states[0] = -94.165829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485060631, states[0] = 16.160928, states[40]= 0.003306
Saving checkpoint... 
Iteration: 1495448836, states[0] = -94.624108, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.538782
 - CaMKt in component CaMK (millimolar): 0.004213
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.475887
 - nass in component intracellular_ions (millimolar): 6.475973
 - ki in component intracellular_ions (millimolar): 145.435993
 - kss in component intracellular_ions (millimolar): 145.435978
 - cansr in component intracellular_ions (millimolar): 1.591004
 - cajsr in component intracellular_ions (millimolar): 1.590310
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003754
 - hf in component INa (dimensionless): 0.873556
 - hs in component INa (dimensionless): 0.873557
 - j in component INa (dimensionless): 0.873563
 - hsp in component INa (dimensionless): 0.713832
 - jp in component INa (dimensionless): 0.873566
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719342
 - hLp in component INaL (dimensionless): 0.511277
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891859
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931660
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975447
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002715
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097724
 - xs1 in component IKs (dimensionless): 0.125446
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997431
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:40:49 (26972): called boinc_finish(0)

</stderr_txt>
]]>


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