𝕏

Task 56134101

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243_1
Workunit 26658662
Created 4 Jul 2024, 21:01:02 UTC
Sent 5 Jul 2024, 2:24:55 UTC
Report deadline 8 Jul 2024, 2:24:55 UTC
Received 6 Jul 2024, 20:15:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232462
Run time 3 hours 32 min 55 sec
CPU time 3 hours 26 min 58 sec
Validate state Valid
Credit 43.82
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.15 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243_1_r1993112783_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243_1_r1993112783_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.256968
     * GNaL_b in INaL: 0.005723
     * Gto_b in Ito: 0.083696
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031823
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163695
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.272068
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032801
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 4736345, states[0] = -6.284892, states[40]= 0.004969
Saving checkpoint... 
Iteration: 9335250, states[0] = 33.671471, states[40]= 0.535027
Saving checkpoint... 
Iteration: 14373085, states[0] = 18.613241, states[40]= 0.000110
Saving checkpoint... 
Iteration: 19212077, states[0] = 15.069977, states[40]= 0.000090
Saving checkpoint... 
Iteration: 24083177, states[0] = -24.368868, states[40]= 0.000545
Saving checkpoint... 
Iteration: 28952876, states[0] = -75.126973, states[40]= 0.000006
Saving checkpoint... 
Iteration: 33890691, states[0] = 5.226831, states[40]= 0.000215
Saving checkpoint... 
Iteration: 38580109, states[0] = -23.263714, states[40]= 0.000391
Saving checkpoint... 
Iteration: 43395826, states[0] = -0.751447, states[40]= 0.000362
Saving checkpoint... 
Iteration: 48197107, states[0] = 22.092962, states[40]= 0.000010
Saving checkpoint... 
Iteration: 52973616, states[0] = -84.759149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57637985, states[0] = -84.731672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62526810, states[0] = 23.157810, states[40]= 0.000017
Saving checkpoint... 
Iteration: 67473008, states[0] = -84.792410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72094073, states[0] = -48.131109, states[40]= 0.000118
Saving checkpoint... 
Iteration: 76877032, states[0] = 11.690643, states[40]= 0.000037
Saving checkpoint... 
Iteration: 81773355, states[0] = -67.266709, states[40]= 0.000015
Saving checkpoint... 
Iteration: 86705340, states[0] = 14.423306, states[40]= 0.000018
Saving checkpoint... 
Iteration: 91609774, states[0] = -73.711035, states[40]= 0.000006
Saving checkpoint... 
Iteration: 96586004, states[0] = -41.197479, states[40]= 0.000196
Saving checkpoint... 
Iteration: 101285035, states[0] = -83.163119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106118914, states[0] = -83.529205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110834371, states[0] = 29.385530, states[40]= 0.030625
Saving checkpoint... 
Iteration: 115379226, states[0] = 6.967234, states[40]= 0.000090
Saving checkpoint... 
Iteration: 120075358, states[0] = -30.223220, states[40]= 0.000293
Saving checkpoint... 
Iteration: 124889182, states[0] = -3.607672, states[40]= 0.000311
Saving checkpoint... 
Iteration: 129489845, states[0] = 33.182138, states[40]= 0.891862
Saving checkpoint... 
Iteration: 134328487, states[0] = 28.563789, states[40]= 0.113709
Saving checkpoint... 
Iteration: 139247931, states[0] = -40.816861, states[40]= 0.000195
Saving checkpoint... 
Iteration: 143777419, states[0] = -81.383480, states[40]= 0.000002
Saving checkpoint... 
Iteration: 148602753, states[0] = -72.137938, states[40]= 0.000007
Saving checkpoint... 
Iteration: 153317118, states[0] = -85.046043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158148252, states[0] = -85.028674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 163344969, states[0] = 25.558752, states[40]= 0.000097
Saving checkpoint... 
Iteration: 167932181, states[0] = -69.145378, states[40]= 0.000011
Saving checkpoint... 
Iteration: 172471371, states[0] = -84.932297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177254191, states[0] = -54.201671, states[40]= 0.000061
Saving checkpoint... 
Iteration: 181868400, states[0] = 10.155126, states[40]= 0.000046
Saving checkpoint... 
Iteration: 186449453, states[0] = -84.427586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191282434, states[0] = -84.437718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196315571, states[0] = 35.194478, states[40]= 1.182220
Saving checkpoint... 
Iteration: 201094873, states[0] = -68.140780, states[40]= 0.000013
Saving checkpoint... 
Iteration: 205818465, states[0] = 28.363552, states[40]= 0.322378
Saving checkpoint... 
Iteration: 210789335, states[0] = -84.766418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215548156, states[0] = -5.360612, states[40]= 0.000329
Saving checkpoint... 
Iteration: 220106029, states[0] = -83.066028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225095218, states[0] = -72.363412, states[40]= 0.000007
Saving checkpoint... 
Iteration: 229767282, states[0] = -80.073193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 234394907, states[0] = -27.084300, states[40]= 0.000285
Saving checkpoint... 
Iteration: 238542791, states[0] = -1.723413, states[40]= 0.000271
Saving checkpoint... 
Iteration: 243344505, states[0] = 21.601977, states[40]= 0.000008
Saving checkpoint... 
Iteration: 248069304, states[0] = -39.438713, states[40]= 0.000211
Saving checkpoint... 
Iteration: 252532001, states[0] = 7.059492, states[40]= 0.000086
Saving checkpoint... 
Iteration: 257137116, states[0] = -85.011000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261904316, states[0] = -43.492984, states[40]= 0.000160
Saving checkpoint... 
Iteration: 266755119, states[0] = -68.374173, states[40]= 0.000012
Saving checkpoint... 
Iteration: 271465965, states[0] = -84.977935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276320023, states[0] = 29.528257, states[40]= 0.013534
Saving checkpoint... 
Iteration: 281038995, states[0] = -2.230475, states[40]= 0.000281
Saving checkpoint... 
Iteration: 285535339, states[0] = 1.154924, states[40]= 0.000208
Saving checkpoint... 
Iteration: 290056545, states[0] = -27.835177, states[40]= 0.000287
Saving checkpoint... 
Iteration: 294702913, states[0] = -0.716734, states[40]= 0.000251
Saving checkpoint... 
Iteration: 299210455, states[0] = -10.791607, states[40]= 0.000334
Saving checkpoint... 
Iteration: 304055061, states[0] = -27.711928, states[40]= 0.000285
Saving checkpoint... 
Iteration: 308501804, states[0] = 23.173630, states[40]= 0.000019
Saving checkpoint... 
Iteration: 313366965, states[0] = 0.069348, states[40]= 0.000232
Saving checkpoint... 
Iteration: 318202752, states[0] = -3.157114, states[40]= 0.000297
Saving checkpoint... 
Iteration: 322893084, states[0] = -36.668820, states[40]= 0.000243
Saving checkpoint... 
Iteration: 327466169, states[0] = -85.034448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332198479, states[0] = 0.003195, states[40]= 0.000234
Saving checkpoint... 
Iteration: 336746466, states[0] = -65.846936, states[40]= 0.000017
Saving checkpoint... 
Iteration: 341206552, states[0] = -11.207948, states[40]= 0.000329
Saving checkpoint... 
Iteration: 345898550, states[0] = -46.965240, states[40]= 0.000120
Saving checkpoint... 
Iteration: 350504880, states[0] = 19.022270, states[40]= 0.000005
Saving checkpoint... 
Iteration: 355331745, states[0] = 22.473035, states[40]= 0.000013
Saving checkpoint... 
Iteration: 360278528, states[0] = -84.825021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364980656, states[0] = 29.309450, states[40]= 0.004768
Saving checkpoint... 
Iteration: 369716455, states[0] = -29.499383, states[40]= 0.000288
Saving checkpoint... 
Iteration: 374441556, states[0] = -84.789888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379136298, states[0] = 28.312879, states[40]= 0.166426
Saving checkpoint... 
Iteration: 383681991, states[0] = 9.829066, states[40]= 0.000050
Saving checkpoint... 
Iteration: 388494846, states[0] = 22.610599, states[40]= 0.000014
Saving checkpoint... 
Iteration: 393023635, states[0] = 2.090111, states[40]= 0.000185
Saving checkpoint... 
Iteration: 397753130, states[0] = -82.138066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402303743, states[0] = 29.091705, states[40]= 0.053069
Saving checkpoint... 
Iteration: 407124500, states[0] = -85.025961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411705725, states[0] = -20.284442, states[40]= 0.000266
Saving checkpoint... 
Iteration: 416389793, states[0] = -44.703782, states[40]= 0.000145
Saving checkpoint... 
Iteration: 421256363, states[0] = -84.068202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426109517, states[0] = -84.878434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430779247, states[0] = -84.921352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435257372, states[0] = -84.365133, states[40]= 0.000001
Saving checkpoint... 
Iteration: 439892677, states[0] = -51.626473, states[40]= 0.000078
Saving checkpoint... 
Iteration: 444809817, states[0] = 28.400029, states[40]= 0.001189
Saving checkpoint... 
Iteration: 449664500, states[0] = 17.261541, states[40]= 0.000008
Saving checkpoint... 
Iteration: 454387074, states[0] = -46.126681, states[40]= 0.000129
Saving checkpoint... 
Iteration: 459255332, states[0] = -84.394878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 464055789, states[0] = -50.111665, states[40]= 0.000091
Saving checkpoint... 
Iteration: 468967330, states[0] = 29.531424, states[40]= 0.014003
Saving checkpoint... 
Iteration: 473793496, states[0] = 28.312945, states[40]= 0.166518
Saving checkpoint... 
Iteration: 478518328, states[0] = -1.204110, states[40]= 0.000260
Saving checkpoint... 
Iteration: 483250580, states[0] = -84.128136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488085731, states[0] = -84.388492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492730597, states[0] = -65.412988, states[40]= 0.000017
Saving checkpoint... 
Iteration: 497471948, states[0] = 28.163532, states[40]= 0.000913
Saving checkpoint... 
Iteration: 502324311, states[0] = 18.248055, states[40]= 0.000006
Saving checkpoint... 
Iteration: 506816628, states[0] = 22.458842, states[40]= 0.000012
Saving checkpoint... 
Iteration: 511532500, states[0] = -25.162181, states[40]= 0.000277
Saving checkpoint... 
Iteration: 515977562, states[0] = 24.982333, states[40]= 0.000063
Saving checkpoint... 
Iteration: 520877621, states[0] = -42.420350, states[40]= 0.000173
Saving checkpoint... 
Iteration: 525654478, states[0] = 18.756924, states[40]= 0.000006
Saving checkpoint... 
Iteration: 530013444, states[0] = -1.493264, states[40]= 0.000267
Saving checkpoint... 
Iteration: 535022569, states[0] = -14.204962, states[40]= 0.000304
Saving checkpoint... 
Iteration: 539873827, states[0] = -39.911992, states[40]= 0.000204
Saving checkpoint... 
Iteration: 544696002, states[0] = -25.369280, states[40]= 0.000276
Saving checkpoint... 
Iteration: 549541011, states[0] = -41.880025, states[40]= 0.000180
Saving checkpoint... 
Iteration: 554356678, states[0] = -18.173815, states[40]= 0.000272
Saving checkpoint... 
Iteration: 559089263, states[0] = -84.770348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563653160, states[0] = 17.224879, states[40]= 0.000008
Saving checkpoint... 
Iteration: 568571406, states[0] = -83.120246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573384463, states[0] = -58.589193, states[40]= 0.000038
Saving checkpoint... 
Iteration: 578250972, states[0] = -84.710577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582954507, states[0] = 29.454676, states[40]= 0.023727
Saving checkpoint... 
Iteration: 587748960, states[0] = -84.685029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592284194, states[0] = 28.961487, states[40]= 0.065077
Saving checkpoint... 
Iteration: 597110949, states[0] = 30.166160, states[40]= 0.589307
Saving checkpoint... 
Iteration: 601929842, states[0] = -84.922996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606598861, states[0] = -84.954416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 611369342, states[0] = -43.431661, states[40]= 0.000160
Saving checkpoint... 
Iteration: 616083861, states[0] = -84.771523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620551339, states[0] = -65.682630, states[40]= 0.000017
Saving checkpoint... 
Iteration: 625084428, states[0] = -84.794682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629776239, states[0] = 28.302196, states[40]= 0.302919
Saving checkpoint... 
Iteration: 634411609, states[0] = -84.697693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638842863, states[0] = -10.346903, states[40]= 0.000335
Saving checkpoint... 
Iteration: 643150642, states[0] = 13.683258, states[40]= 0.000020
Saving checkpoint... 
Iteration: 647939793, states[0] = 29.221691, states[40]= 0.478909
Saving checkpoint... 
Iteration: 652490633, states[0] = 8.157900, states[40]= 0.000070
Saving checkpoint... 
Iteration: 657270795, states[0] = 32.055663, states[40]= 0.778388
Saving checkpoint... 
Iteration: 662078884, states[0] = -84.762625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666775802, states[0] = 28.713296, states[40]= 0.092259
Saving checkpoint... 
Iteration: 671454180, states[0] = 28.290063, states[40]= 0.001042
Saving checkpoint... 
Iteration: 676116158, states[0] = 29.321979, states[40]= 0.004850
Saving checkpoint... 
Iteration: 680612170, states[0] = 29.514534, states[40]= 0.017874
Saving checkpoint... 
Iteration: 685450267, states[0] = 28.993259, states[40]= 0.002597
Saving checkpoint... 
Iteration: 690204866, states[0] = -56.846528, states[40]= 0.000046
Saving checkpoint... 
Iteration: 694870798, states[0] = -56.478831, states[40]= 0.000048
Saving checkpoint... 
Iteration: 699589996, states[0] = -84.953546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704430202, states[0] = 29.801733, states[40]= 0.121691
Saving checkpoint... 
Iteration: 709274772, states[0] = 29.406848, states[40]= 0.027883
Saving checkpoint... 
Iteration: 713887619, states[0] = -81.733575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718436597, states[0] = 28.523787, states[40]= 0.119638
Saving checkpoint... 
Iteration: 723065437, states[0] = -84.567700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727883817, states[0] = -79.680292, states[40]= 0.000002
Saving checkpoint... 
Iteration: 732683025, states[0] = -33.392200, states[40]= 0.000274
Saving checkpoint... 
Iteration: 737311986, states[0] = 10.803340, states[40]= 0.000040
Saving checkpoint... 
Iteration: 741977097, states[0] = 11.589706, states[40]= 0.000033
Saving checkpoint... 
Iteration: 746786557, states[0] = 25.596963, states[40]= 0.000099
Saving checkpoint... 
Iteration: 751472501, states[0] = 14.118378, states[40]= 0.000018
Saving checkpoint... 
Iteration: 756335827, states[0] = -17.203191, states[40]= 0.000278
Saving checkpoint... 
Iteration: 761100417, states[0] = 28.905926, states[40]= 0.070760
Saving checkpoint... 
Iteration: 765931351, states[0] = 28.400560, states[40]= 0.143526
Saving checkpoint... 
Iteration: 770647011, states[0] = 6.946954, states[40]= 0.000088
Saving checkpoint... 
Iteration: 775296184, states[0] = 18.758992, states[40]= 0.000006
Saving checkpoint... 
Iteration: 779828356, states[0] = -9.759642, states[40]= 0.000338
Saving checkpoint... 
Iteration: 784738817, states[0] = -84.836779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789570259, states[0] = -84.817341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794409502, states[0] = -84.898458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799117554, states[0] = 24.159060, states[40]= 0.000036
Saving checkpoint... 
Iteration: 803800458, states[0] = 14.216038, states[40]= 0.000017
Saving checkpoint... 
Iteration: 808523752, states[0] = -53.292240, states[40]= 0.000066
Saving checkpoint... 
Iteration: 813221057, states[0] = -84.453409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818072035, states[0] = -84.875741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822904105, states[0] = -84.865795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827454309, states[0] = 20.728547, states[40]= 0.000006
Saving checkpoint... 
Iteration: 832138085, states[0] = 9.130287, states[40]= 0.000057
Saving checkpoint... 
Iteration: 836876974, states[0] = -82.682196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841569653, states[0] = -84.873901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846365264, states[0] = -70.489690, states[40]= 0.000009
Saving checkpoint... 
Iteration: 851084635, states[0] = 32.346235, states[40]= 0.807702
Saving checkpoint... 
Iteration: 855574143, states[0] = -84.941178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860353564, states[0] = -55.527326, states[40]= 0.000053
Saving checkpoint... 
Iteration: 865153717, states[0] = -10.548853, states[40]= 0.000334
Saving checkpoint... 
Iteration: 869583917, states[0] = 29.766847, states[40]= 0.545855
Saving checkpoint... 
Iteration: 874120125, states[0] = 18.462913, states[40]= 0.000006
Saving checkpoint... 
Iteration: 878823933, states[0] = -17.714008, states[40]= 0.000275
Saving checkpoint... 
Iteration: 883672187, states[0] = -39.096989, states[40]= 0.000215
Saving checkpoint... 
Iteration: 888489606, states[0] = -17.673777, states[40]= 0.000275
Saving checkpoint... 
Iteration: 893316122, states[0] = -8.519114, states[40]= 0.000342
Saving checkpoint... 
Iteration: 898060266, states[0] = -84.822383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902680452, states[0] = -52.546704, states[40]= 0.000071
Saving checkpoint... 
Iteration: 907479678, states[0] = -6.246688, states[40]= 0.000335
Saving checkpoint... 
Iteration: 912195230, states[0] = -75.303172, states[40]= 0.000005
Saving checkpoint... 
Iteration: 916880948, states[0] = -84.613509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921715887, states[0] = -84.671875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 926332545, states[0] = -36.367784, states[40]= 0.000247
Saving checkpoint... 
Iteration: 931092185, states[0] = 29.039989, states[40]= 0.002774
Saving checkpoint... 
Iteration: 935843891, states[0] = -52.662220, states[40]= 0.000071
Saving checkpoint... 
Iteration: 940350936, states[0] = -63.045985, states[40]= 0.000023
Saving checkpoint... 
Iteration: 945060443, states[0] = -84.881350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949710632, states[0] = -84.599005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954426540, states[0] = 28.073834, states[40]= 0.000821
Saving checkpoint... 
Iteration: 958947479, states[0] = 16.910125, states[40]= 0.000008
Saving checkpoint... 
Iteration: 963552503, states[0] = -84.801578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968184904, states[0] = -68.151623, states[40]= 0.000012
Saving checkpoint... 
Iteration: 972904684, states[0] = 34.980208, states[40]= 1.152920
Saving checkpoint... 
Iteration: 977613322, states[0] = 16.246496, states[40]= 0.000010
Saving checkpoint... 
Iteration: 982113007, states[0] = 16.159922, states[40]= 0.000010
Saving checkpoint... 
Iteration: 986717740, states[0] = -84.812464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991524796, states[0] = -80.302491, states[40]= 0.000002
Saving checkpoint... 
Iteration: 996095196, states[0] = 25.488615, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1000821147, states[0] = -31.015869, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1005766543, states[0] = 22.572421, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1010573786, states[0] = 28.458874, states[40]= 0.131616
Saving checkpoint... 
Iteration: 1015255710, states[0] = 27.360096, states[40]= 0.000411
Saving checkpoint... 
Iteration: 1019822376, states[0] = -35.260069, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1024571938, states[0] = 28.354204, states[40]= 0.155090
Saving checkpoint... 
Iteration: 1029164471, states[0] = -48.115165, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1033756691, states[0] = 26.147477, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1038470115, states[0] = -11.105499, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1043248919, states[0] = 28.721395, states[40]= 0.001738
Saving checkpoint... 
Iteration: 1047823116, states[0] = -39.984765, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1052490472, states[0] = -41.510961, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1057156360, states[0] = -41.095163, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1061904176, states[0] = 29.036628, states[40]= 0.058535
Saving checkpoint... 
Iteration: 1066723987, states[0] = -84.973383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071468341, states[0] = -13.323495, states[40]= 0.000313
Saving checkpoint... 
Iteration: 1076214816, states[0] = -84.883295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081039045, states[0] = -84.769431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085866713, states[0] = -84.674807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090382668, states[0] = -84.912350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094989930, states[0] = -46.404407, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1099812103, states[0] = -32.188206, states[40]= 0.000282
Saving checkpoint... 
Iteration: 1104613108, states[0] = 7.366009, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1109291116, states[0] = -4.083486, states[40]= 0.000311
Saving checkpoint... 
Iteration: 1114186083, states[0] = -83.825326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118735245, states[0] = 29.531978, states[40]= 0.016432
Saving checkpoint... 
Iteration: 1123696871, states[0] = -84.685954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128377164, states[0] = -84.890360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132670050, states[0] = -70.583921, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1137286945, states[0] = -2.473452, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1141917909, states[0] = 23.484214, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1146392881, states[0] = 28.312842, states[40]= 0.167184
Saving checkpoint... 
Iteration: 1150859747, states[0] = -84.659885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155678470, states[0] = -82.671485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160064630, states[0] = 29.537521, states[40]= 0.015343
Saving checkpoint... 
Iteration: 1164801631, states[0] = -26.702101, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1169416375, states[0] = 22.831849, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1174112546, states[0] = 1.776726, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1178968042, states[0] = -28.315846, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1183775969, states[0] = 3.894150, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1188522680, states[0] = -84.658640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193204445, states[0] = -84.891614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198034500, states[0] = -84.857961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202842191, states[0] = -83.370004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207406186, states[0] = 26.062646, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1212077419, states[0] = 23.561525, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1216839905, states[0] = -83.052717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221431248, states[0] = 10.070311, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1226121614, states[0] = -16.341794, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1230841261, states[0] = -83.852391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1235565248, states[0] = 28.023370, states[40]= 0.000775
Saving checkpoint... 
Iteration: 1240292928, states[0] = -25.073043, states[40]= 0.000275
Saving checkpoint... 
Iteration: 1245128694, states[0] = -29.141307, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1249295354, states[0] = -29.706190, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1253852029, states[0] = -84.707417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258677618, states[0] = -84.488027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263302662, states[0] = -41.417356, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1268197840, states[0] = -84.897197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273041022, states[0] = 35.233645, states[40]= 1.199355
Saving checkpoint... 
Iteration: 1277831620, states[0] = -81.923822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282548698, states[0] = 29.020138, states[40]= 0.060232
Saving checkpoint... 
Iteration: 1287199716, states[0] = -84.936947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291846662, states[0] = -84.674284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296333701, states[0] = -83.611093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300539705, states[0] = 32.269756, states[40]= 0.801273
Saving checkpoint... 
Iteration: 1305121815, states[0] = -27.919644, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1309933890, states[0] = 0.195902, states[40]= 0.000228
Saving checkpoint... 
Iteration: 1314563513, states[0] = 25.417084, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1319295645, states[0] = -39.541109, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1323796222, states[0] = -40.893808, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1328237544, states[0] = 20.750048, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1332900381, states[0] = 22.643091, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1337587938, states[0] = 8.835669, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1342278623, states[0] = -19.198723, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1347043867, states[0] = 29.350862, states[40]= 0.032991
Saving checkpoint... 
Iteration: 1351802646, states[0] = -53.100670, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1356493311, states[0] = -83.297761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361340919, states[0] = -84.693901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1365992588, states[0] = -83.369244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370462012, states[0] = -45.897357, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1375152335, states[0] = -79.491402, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1379762751, states[0] = -2.520573, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1384571186, states[0] = 17.168415, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1389482727, states[0] = -77.761190, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1394084844, states[0] = 6.819000, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1398951258, states[0] = -35.406672, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1403784522, states[0] = -35.962228, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1408526698, states[0] = 32.581008, states[40]= 0.468199
Saving checkpoint... 
Iteration: 1413239450, states[0] = 14.271345, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1417831180, states[0] = -84.591667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422665779, states[0] = -84.639781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427353094, states[0] = -84.936044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431936886, states[0] = -20.001653, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1436556944, states[0] = 22.499907, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1441538365, states[0] = 29.485661, states[40]= 0.007647
Saving checkpoint... 
Iteration: 1446223552, states[0] = 21.997301, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1450826791, states[0] = -84.551980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455536640, states[0] = 29.510728, states[40]= 0.008619
Saving checkpoint... 
Iteration: 1460351233, states[0] = -84.948829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465184436, states[0] = -84.952109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470032831, states[0] = 29.501757, states[40]= 0.020621
Saving checkpoint... 
Iteration: 1474585943, states[0] = -1.773748, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1479505465, states[0] = -84.829806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484256696, states[0] = -8.031724, states[40]= 0.000341
Saving checkpoint... 
Iteration: 1488946859, states[0] = -41.526675, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1493683968, states[0] = -82.740423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498325312, states[0] = -84.645293, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.849004
 - CaMKt in component CaMK (millimolar): 0.216659
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.283403
 - nass in component intracellular_ions (millimolar): 7.283757
 - ki in component intracellular_ions (millimolar): 143.837467
 - kss in component intracellular_ions (millimolar): 143.837432
 - cansr in component intracellular_ions (millimolar): 3.334189
 - cajsr in component intracellular_ions (millimolar): 1.926515
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009955
 - hf in component INa (dimensionless): 0.584334
 - hs in component INa (dimensionless): 0.583283
 - j in component INa (dimensionless): 0.553627
 - hsp in component INa (dimensionless): 0.331769
 - jp in component INa (dimensionless): 0.511842
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.183015
 - hLp in component INaL (dimensionless): 0.074647
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999237
 - iS in component Ito (dimensionless): 0.131126
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999238
 - iSp in component Ito (dimensionless): 0.146591
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677271
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928667
 - jca in component ICaL (dimensionless): 0.911323
 - ffp in component ICaL (dimensionless): 0.998925
 - fcafp in component ICaL (dimensionless): 0.999939
 - nca in component ICaL (dimensionless): 0.041914
 - xrf in component IKr (dimensionless): 0.100982
 - xrs in component IKr (dimensionless): 0.872911
 - xs1 in component IKs (dimensionless): 0.570730
 - xs2 in component IKs (dimensionless): 0.007213
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:11:28 (74984): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243_1_r1993112783_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_333-conf_243_1_r1993112783_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.256968
     * GNaL_b in INaL: 0.005723
     * Gto_b in Ito: 0.083696
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031823
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163695
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.272068
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032801
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1498325312
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.645293 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.849004
 - CaMKt in component CaMK (millimolar): 0.216659
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.283403
 - nass in component intracellular_ions (millimolar): 7.283757
 - ki in component intracellular_ions (millimolar): 143.837467
 - kss in component intracellular_ions (millimolar): 143.837432
 - cansr in component intracellular_ions (millimolar): 3.334189
 - cajsr in component intracellular_ions (millimolar): 1.926515
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009955
 - hf in component INa (dimensionless): 0.584334
 - hs in component INa (dimensionless): 0.583283
 - j in component INa (dimensionless): 0.553627
 - hsp in component INa (dimensionless): 0.331769
 - jp in component INa (dimensionless): 0.511842
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.183015
 - hLp in component INaL (dimensionless): 0.074647
 - a in component Ito (dimensionless): 0.001228
 - iF in component Ito (dimensionless): 0.999237
 - iS in component Ito (dimensionless): 0.131126
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999238
 - iSp in component Ito (dimensionless): 0.146591
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677271
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928667
 - jca in component ICaL (dimensionless): 0.911323
 - ffp in component ICaL (dimensionless): 0.998925
 - fcafp in component ICaL (dimensionless): 0.999939
 - nca in component ICaL (dimensionless): 0.041914
 - xrf in component IKr (dimensionless): 0.100982
 - xrs in component IKr (dimensionless): 0.872911
 - xs1 in component IKs (dimensionless): 0.570730
 - xs2 in component IKs (dimensionless): 0.007213
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:14:55 (75249): called boinc_finish(0)

</stderr_txt>
]]>


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