𝕏

Task 56133528

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_10000-conf_543_1
Workunit 26658376
Created 4 Jul 2024, 21:00:46 UTC
Sent 5 Jul 2024, 2:21:53 UTC
Report deadline 8 Jul 2024, 2:21:53 UTC
Received 8 Jul 2024, 3:46:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 40 min 31 sec
CPU time 38 min 1 sec
Validate state Valid
Credit 45.65
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.58 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_10000-conf_543.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_10000-conf_543_1_r119750477_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_10000-conf_543_1_r119750477_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.427590
     * GNaL_b in INaL: 0.005753
     * Gto_b in Ito: 0.084303
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031806
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.162934
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.391338
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033798
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10128479, states[0] = -16.872919, states[40]= 0.001465
Saving checkpoint... 
Iteration: 19528368, states[0] = -93.935382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28275310, states[0] = -93.893463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38508155, states[0] = -93.865804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47090664, states[0] = -93.862818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57325699, states[0] = -93.852985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67152361, states[0] = -93.851110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76300359, states[0] = -93.866015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86130820, states[0] = -93.870603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96329036, states[0] = -93.863194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106096443, states[0] = -93.870661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115704397, states[0] = -93.877870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124478895, states[0] = -93.835543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135991022, states[0] = -93.873843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146875188, states[0] = -93.849631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156582847, states[0] = -93.855087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166554721, states[0] = -93.855657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175439531, states[0] = -93.796810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184739544, states[0] = -93.834556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195202798, states[0] = -70.068600, states[40]= 0.000010
Saving checkpoint... 
Iteration: 203677955, states[0] = -93.836508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214171507, states[0] = -93.835358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225306076, states[0] = -93.565000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235251454, states[0] = -93.345280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243907730, states[0] = -93.835844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252556206, states[0] = -93.841618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262264678, states[0] = -93.844179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272679605, states[0] = -93.840712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281444418, states[0] = -93.858097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292471934, states[0] = -93.842231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303208098, states[0] = -93.837905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314122457, states[0] = -93.835300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324378436, states[0] = -93.834829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334153227, states[0] = -93.835219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344497123, states[0] = -93.834619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353981812, states[0] = -93.835547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364466885, states[0] = -93.834646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372662023, states[0] = -93.840721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382158495, states[0] = -93.845201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392346874, states[0] = -93.843229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402457661, states[0] = -93.842236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413321694, states[0] = -93.837354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423365906, states[0] = -93.837185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432941108, states[0] = -93.839000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442921852, states[0] = -93.839091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454526318, states[0] = -93.834466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465427422, states[0] = -93.785454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476600895, states[0] = -93.854098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485592539, states[0] = -93.864757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493832382, states[0] = -93.835750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502821937, states[0] = -93.839587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514090692, states[0] = -93.835163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523987955, states[0] = -93.835366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532580063, states[0] = -93.841145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542447621, states[0] = -93.842183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552960131, states[0] = -93.838785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562465363, states[0] = -93.842015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572154958, states[0] = -93.845056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581145421, states[0] = -93.867234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592700436, states[0] = -93.840249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603326220, states[0] = -93.837151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613472482, states[0] = -93.836639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622700763, states[0] = -93.840217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632924367, states[0] = -93.838892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642580369, states[0] = -93.841035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652062887, states[0] = -93.846098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662047971, states[0] = -93.846281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672043656, states[0] = -93.846328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681970210, states[0] = -93.847320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692731155, states[0] = -93.839953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702929242, states[0] = -93.838798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713746263, states[0] = -93.835750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724054416, states[0] = -93.835031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731559831, states[0] = -93.854777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738137472, states[0] = -93.837771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747886604, states[0] = -93.838983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759009239, states[0] = -93.835091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769013602, states[0] = -93.835072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778259270, states[0] = -93.837232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787664044, states[0] = -93.840301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797426777, states[0] = -93.842112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808306517, states[0] = -93.837024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819115167, states[0] = -93.834816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829587698, states[0] = -93.834008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839996780, states[0] = -93.833464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849724751, states[0] = -93.833797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858293242, states[0] = -93.837024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868439056, states[0] = -93.836499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877934566, states[0] = -93.838599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887195778, states[0] = -93.844286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898896157, states[0] = -93.835204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910242520, states[0] = -93.292336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920710705, states[0] = -93.876490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931367482, states[0] = -93.859600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941775328, states[0] = -93.850177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952123084, states[0] = -93.845060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961489246, states[0] = -93.856261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971514183, states[0] = -93.855631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981162202, states[0] = -93.866241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991411020, states[0] = -93.858303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001695091, states[0] = -93.851623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012116677, states[0] = -93.845078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021353577, states[0] = -93.859922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031340321, states[0] = -93.860308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040593394, states[0] = -93.864379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051113783, states[0] = -93.867929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060935088, states[0] = -93.874408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071476492, states[0] = -93.856478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081280302, states[0] = -93.862127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091535525, states[0] = -93.854997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101078298, states[0] = -93.869193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112079997, states[0] = -93.845432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121061687, states[0] = -93.869792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130343162, states[0] = -93.660916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141885764, states[0] = -93.848133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153258220, states[0] = -93.836870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163190348, states[0] = -93.837132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174149992, states[0] = -93.834401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183752071, states[0] = -93.835276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194730264, states[0] = -93.833452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204426033, states[0] = -93.833888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214143201, states[0] = -93.834375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223107225, states[0] = -93.837429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232225393, states[0] = -93.843627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242068357, states[0] = -93.845452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252423004, states[0] = -93.841700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261614581, states[0] = -93.853032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272538925, states[0] = -93.840732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282458515, states[0] = -93.841368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292118802, states[0] = -93.844779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301570612, states[0] = -93.853973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312295328, states[0] = -93.842828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322386116, states[0] = -93.841958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333154020, states[0] = -93.837118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343807301, states[0] = -93.834980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353927264, states[0] = -93.834688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363512956, states[0] = -93.835777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373237739, states[0] = -93.836735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383604067, states[0] = -93.835484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392537291, states[0] = -93.840628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404146484, states[0] = -93.834183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415036388, states[0] = 29.130396, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1425445817, states[0] = -93.800610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434197555, states[0] = -93.834057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444692761, states[0] = -93.833258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454936962, states[0] = -93.832934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464232587, states[0] = -93.833964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474837412, states[0] = -93.833038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485891098, states[0] = -93.875349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496723408, states[0] = -93.850592, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.708803
 - CaMKt in component CaMK (millimolar): 0.001021
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.666176
 - nass in component intracellular_ions (millimolar): 6.666301
 - ki in component intracellular_ions (millimolar): 145.201577
 - kss in component intracellular_ions (millimolar): 145.201569
 - cansr in component intracellular_ions (millimolar): 1.839549
 - cajsr in component intracellular_ions (millimolar): 1.839463
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.004082
 - hf in component INa (dimensionless): 0.857709
 - hs in component INa (dimensionless): 0.857709
 - j in component INa (dimensionless): 0.857709
 - hsp in component INa (dimensionless): 0.685175
 - jp in component INa (dimensionless): 0.857709
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.696578
 - hLp in component INaL (dimensionless): 0.500776
 - a in component Ito (dimensionless): 0.000676
 - iF in component Ito (dimensionless): 0.999839
 - iS in component Ito (dimensionless): 0.999836
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999839
 - iSp in component Ito (dimensionless): 0.999839
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005633
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002158
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997633
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:46:25 (26230): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge