𝕏

Task 56133126

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_666-conf_442_1
Workunit 26658175
Created 4 Jul 2024, 21:00:31 UTC
Sent 5 Jul 2024, 2:19:24 UTC
Report deadline 8 Jul 2024, 2:19:28 UTC
Received 8 Jul 2024, 2:50:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 17 sec
CPU time 39 min 1 sec
Validate state Valid
Credit 45.36
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.55 MB
Peak swap size 391.75 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_666-conf_442.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_666-conf_442_1_r1861507470_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_666-conf_442_1_r1861507470_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.586080
     * GNaL_b in INaL: 0.005877
     * Gto_b in Ito: 0.083608
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031795
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163781
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.348379
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032066
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10303473, states[0] = -84.702933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 19722719, states[0] = 15.963088, states[40]= 0.000056
Saving checkpoint... 
Iteration: 28695467, states[0] = 28.919934, states[40]= 0.000133
Saving checkpoint... 
Iteration: 39595697, states[0] = -84.546565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50194774, states[0] = -84.169670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60129367, states[0] = -47.763352, states[40]= 0.000040
Saving checkpoint... 
Iteration: 70177701, states[0] = -83.991519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79920861, states[0] = -84.511538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89080460, states[0] = 3.737579, states[40]= 0.000196
Saving checkpoint... 
Iteration: 100160388, states[0] = -81.133954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111566738, states[0] = -84.408273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120958443, states[0] = -84.626121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131424314, states[0] = -2.540907, states[40]= 0.000303
Saving checkpoint... 
Iteration: 140244972, states[0] = -84.458557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149467416, states[0] = -48.169712, states[40]= 0.000038
Saving checkpoint... 
Iteration: 159238864, states[0] = -84.423786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169640020, states[0] = -84.654952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180530862, states[0] = -84.139799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190463592, states[0] = -41.800186, states[40]= 0.000077
Saving checkpoint... 
Iteration: 200237946, states[0] = -84.407466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208958352, states[0] = -84.612855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219037194, states[0] = 29.302502, states[40]= 0.000196
Saving checkpoint... 
Iteration: 229492224, states[0] = -73.163939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239767953, states[0] = -7.079362, states[40]= 0.000320
Saving checkpoint... 
Iteration: 248992667, states[0] = -84.683686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259624900, states[0] = -84.604460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268789031, states[0] = -29.021061, states[40]= 0.000186
Saving checkpoint... 
Iteration: 278871950, states[0] = -84.161099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288983051, states[0] = -84.660341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297089458, states[0] = 4.645729, states[40]= 0.000178
Saving checkpoint... 
Iteration: 304644492, states[0] = -84.646902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314528299, states[0] = -84.050967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325664826, states[0] = -84.685028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336150222, states[0] = -55.729051, states[40]= 0.000014
Saving checkpoint... 
Iteration: 346031680, states[0] = 31.717376, states[40]= 0.013030
Saving checkpoint... 
Iteration: 355321063, states[0] = -84.661573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364408953, states[0] = 14.739642, states[40]= 0.000043
Saving checkpoint... 
Iteration: 373558033, states[0] = -84.269704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384647291, states[0] = -84.642354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394196637, states[0] = -84.023462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404154711, states[0] = -56.973555, states[40]= 0.000012
Saving checkpoint... 
Iteration: 414281256, states[0] = -84.544416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423126316, states[0] = -24.866620, states[40]= 0.000194
Saving checkpoint... 
Iteration: 433930313, states[0] = -84.470365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444071679, states[0] = 18.882753, states[40]= 0.000020
Saving checkpoint... 
Iteration: 453776502, states[0] = -4.979780, states[40]= 0.000323
Saving checkpoint... 
Iteration: 462946389, states[0] = -84.528935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472444077, states[0] = -4.955963, states[40]= 0.000323
Saving checkpoint... 
Iteration: 480977397, states[0] = -84.620949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489821403, states[0] = -52.168562, states[40]= 0.000023
Saving checkpoint... 
Iteration: 499728066, states[0] = 25.150199, states[40]= 0.000011
Saving checkpoint... 
Iteration: 510791816, states[0] = -18.589270, states[40]= 0.000205
Saving checkpoint... 
Iteration: 517726382, states[0] = 26.291933, states[40]= 0.000017
Saving checkpoint... 
Iteration: 527447486, states[0] = -5.577907, states[40]= 0.000323
Saving checkpoint... 
Iteration: 536032181, states[0] = 30.155067, states[40]= 0.318255
Saving checkpoint... 
Iteration: 545640168, states[0] = -84.600659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555651841, states[0] = -84.629180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 565008197, states[0] = -84.676176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574254069, states[0] = -84.385111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583444540, states[0] = -0.611479, states[40]= 0.000276
Saving checkpoint... 
Iteration: 593530777, states[0] = -83.821628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603400729, states[0] = 24.786735, states[40]= 0.000010
Saving checkpoint... 
Iteration: 613987216, states[0] = -84.625815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622780708, states[0] = -1.298409, states[40]= 0.000288
Saving checkpoint... 
Iteration: 631860899, states[0] = -83.429511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641085316, states[0] = 16.936470, states[40]= 0.000029
Saving checkpoint... 
Iteration: 648445296, states[0] = 1.264835, states[40]= 0.000242
Saving checkpoint... 
Iteration: 657683732, states[0] = -84.681610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667490454, states[0] = -45.043722, states[40]= 0.000054
Saving checkpoint... 
Iteration: 678495974, states[0] = -50.464973, states[40]= 0.000029
Saving checkpoint... 
Iteration: 688335679, states[0] = -84.649900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698600795, states[0] = -84.419793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707561499, states[0] = -84.162967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716688250, states[0] = -84.682830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723653709, states[0] = -84.609075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 732354678, states[0] = -84.680731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742454917, states[0] = -2.579832, states[40]= 0.000305
Saving checkpoint... 
Iteration: 752364512, states[0] = -84.694586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764010778, states[0] = -84.657618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773844768, states[0] = -62.769520, states[40]= 0.000005
Saving checkpoint... 
Iteration: 783794717, states[0] = -6.626801, states[40]= 0.000321
Saving checkpoint... 
Iteration: 794187790, states[0] = -73.976272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 803000238, states[0] = -84.629985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812457931, states[0] = -2.170290, states[40]= 0.000301
Saving checkpoint... 
Iteration: 822744168, states[0] = 25.175222, states[40]= 0.000011
Saving checkpoint... 
Iteration: 834308142, states[0] = -84.554868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844712886, states[0] = 31.467755, states[40]= 0.516829
Saving checkpoint... 
Iteration: 854666877, states[0] = -84.622684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864079603, states[0] = 25.159316, states[40]= 0.000011
Saving checkpoint... 
Iteration: 874188821, states[0] = -70.094767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 883585658, states[0] = -84.272578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894090378, states[0] = 20.784351, states[40]= 0.000014
Saving checkpoint... 
Iteration: 902809073, states[0] = -15.873966, states[40]= 0.000228
Saving checkpoint... 
Iteration: 911553485, states[0] = -83.980282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920859454, states[0] = -72.242282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931246004, states[0] = -84.209465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943078048, states[0] = 27.527599, states[40]= 0.000040
Saving checkpoint... 
Iteration: 952999003, states[0] = -84.605234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962357888, states[0] = -84.660648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971514190, states[0] = -54.422688, states[40]= 0.000017
Saving checkpoint... 
Iteration: 981958428, states[0] = -84.461067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993259957, states[0] = -84.284443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004583569, states[0] = -84.211984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016153905, states[0] = -22.541950, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1025017444, states[0] = -84.638634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034641943, states[0] = -84.517222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045699846, states[0] = -84.666992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1056639286, states[0] = -84.502473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065847677, states[0] = -49.351872, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1074528517, states[0] = -65.327954, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1085276123, states[0] = -84.353792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094568892, states[0] = -84.049411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103555995, states[0] = -83.797151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113599222, states[0] = -84.281081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122827523, states[0] = -24.352353, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1134144167, states[0] = -5.260369, states[40]= 0.000321
Saving checkpoint... 
Iteration: 1144267899, states[0] = -84.283407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154937117, states[0] = -84.296490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165618160, states[0] = -84.378091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175849910, states[0] = -45.784525, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1185093132, states[0] = 26.275832, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1193919730, states[0] = -84.156595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203767043, states[0] = 23.422275, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1214921235, states[0] = -84.159624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223262794, states[0] = -84.218988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234543212, states[0] = -74.037865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245444549, states[0] = 19.157113, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1254119943, states[0] = 14.836168, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1262963956, states[0] = -84.415093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270932684, states[0] = -84.223752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280405126, states[0] = 30.291744, states[40]= 0.136873
Saving checkpoint... 
Iteration: 1288340672, states[0] = -84.574738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299462763, states[0] = 10.825789, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1311159171, states[0] = -11.682992, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1320915153, states[0] = -84.059259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330748233, states[0] = 31.733858, states[40]= 0.010324
Saving checkpoint... 
Iteration: 1341440233, states[0] = 23.592432, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1352074413, states[0] = 30.059124, states[40]= 0.192385
Saving checkpoint... 
Iteration: 1362435654, states[0] = 26.137928, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1372565038, states[0] = -83.461312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382064579, states[0] = -84.683435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391015732, states[0] = -84.581516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400378472, states[0] = -84.648325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409131653, states[0] = 12.668645, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1420217572, states[0] = -71.960994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430977360, states[0] = -84.434908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442099658, states[0] = 28.837676, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1451435070, states[0] = 28.223217, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1461791269, states[0] = 17.850702, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1470138397, states[0] = 10.579985, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1479528802, states[0] = -42.572770, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1488652745, states[0] = -84.459554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498395070, states[0] = -84.667073, states[40]= 0.000001
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.563157
 - CaMKt in component CaMK (millimolar): 0.038957
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.818404
 - nass in component intracellular_ions (millimolar): 6.818558
 - ki in component intracellular_ions (millimolar): 144.844663
 - kss in component intracellular_ions (millimolar): 144.844635
 - cansr in component intracellular_ions (millimolar): 2.053429
 - cajsr in component intracellular_ions (millimolar): 1.807780
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010245
 - hf in component INa (dimensionless): 0.572894
 - hs in component INa (dimensionless): 0.572741
 - j in component INa (dimensionless): 0.571908
 - hsp in component INa (dimensionless): 0.325831
 - jp in component INa (dimensionless): 0.571219
 - mL in component INaL (dimensionless): 0.000353
 - hL in component INaL (dimensionless): 0.346144
 - hLp in component INaL (dimensionless): 0.150791
 - a in component Ito (dimensionless): 0.001252
 - iF in component Ito (dimensionless): 0.999203
 - iS in component Ito (dimensionless): 0.365297
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999203
 - iSp in component Ito (dimensionless): 0.399548
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842414
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995709
 - jca in component ICaL (dimensionless): 0.998101
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005900
 - xrf in component IKr (dimensionless): 0.000411
 - xrs in component IKr (dimensionless): 0.674427
 - xs1 in component IKs (dimensionless): 0.386536
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996786
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:49:51 (25357): called boinc_finish(0)

</stderr_txt>
]]>


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