𝕏

Task 56133115

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_942_0
Workunit 26658170
Created 4 Jul 2024, 21:00:31 UTC
Sent 5 Jul 2024, 2:19:24 UTC
Report deadline 8 Jul 2024, 2:19:34 UTC
Received 8 Jul 2024, 3:22:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 33 sec
CPU time 38 min 23 sec
Validate state Valid
Credit 43.53
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 391.75 GB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_942.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_942_0_r1410067959_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_575-conf_942_0_r1410067959_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.852456
     * GNaL_b in INaL: 0.005835
     * Gto_b in Ito: 0.084186
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031869
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.163699
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.374530
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033771
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9011732, states[0] = -21.651250, states[40]= 0.000632
Saving checkpoint... 
Iteration: 18344928, states[0] = -84.603078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 29223288, states[0] = -84.299921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39062894, states[0] = -84.678350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47863137, states[0] = -67.939878, states[40]= 0.000003
Saving checkpoint... 
Iteration: 58901475, states[0] = -84.691423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67881403, states[0] = 26.987188, states[40]= 0.000033
Saving checkpoint... 
Iteration: 77861927, states[0] = -84.638224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87328442, states[0] = -84.532844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98383719, states[0] = 12.929795, states[40]= 0.000042
Saving checkpoint... 
Iteration: 107496539, states[0] = -84.724997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117413910, states[0] = -39.870571, states[40]= 0.000093
Saving checkpoint... 
Iteration: 127455472, states[0] = -15.671541, states[40]= 0.000204
Saving checkpoint... 
Iteration: 137741813, states[0] = 27.821697, states[40]= 0.000067
Saving checkpoint... 
Iteration: 147485458, states[0] = -84.797681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158223957, states[0] = -22.863592, states[40]= 0.000174
Saving checkpoint... 
Iteration: 168691102, states[0] = -84.535536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178675961, states[0] = -69.220841, states[40]= 0.000003
Saving checkpoint... 
Iteration: 187639900, states[0] = -84.352640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197579760, states[0] = 7.669544, states[40]= 0.000095
Saving checkpoint... 
Iteration: 204848949, states[0] = -81.085498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213507697, states[0] = -84.290268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224820863, states[0] = -84.791165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232746759, states[0] = -83.844382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242698045, states[0] = 18.828972, states[40]= 0.000013
Saving checkpoint... 
Iteration: 252194898, states[0] = 13.667418, states[40]= 0.000037
Saving checkpoint... 
Iteration: 262246957, states[0] = 19.401822, states[40]= 0.000012
Saving checkpoint... 
Iteration: 271146115, states[0] = 25.952895, states[40]= 0.000017
Saving checkpoint... 
Iteration: 280528515, states[0] = -84.532070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289377570, states[0] = -82.768413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298769235, states[0] = 14.048815, states[40]= 0.000034
Saving checkpoint... 
Iteration: 308371081, states[0] = -84.169748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319169557, states[0] = 20.646489, states[40]= 0.000009
Saving checkpoint... 
Iteration: 329763404, states[0] = 34.712726, states[40]= 0.433381
Saving checkpoint... 
Iteration: 340350760, states[0] = -84.642507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348960452, states[0] = -84.568788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358219726, states[0] = -84.784731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367156950, states[0] = 31.072487, states[40]= 0.002169
Saving checkpoint... 
Iteration: 377270522, states[0] = 5.509313, states[40]= 0.000126
Saving checkpoint... 
Iteration: 387911265, states[0] = 3.231545, states[40]= 0.000164
Saving checkpoint... 
Iteration: 397920476, states[0] = 30.840593, states[40]= 0.001505
Saving checkpoint... 
Iteration: 409233670, states[0] = -48.089314, states[40]= 0.000040
Saving checkpoint... 
Iteration: 418859765, states[0] = -84.720654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428490847, states[0] = -42.089394, states[40]= 0.000075
Saving checkpoint... 
Iteration: 437184165, states[0] = -84.296818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445121128, states[0] = 5.095736, states[40]= 0.000133
Saving checkpoint... 
Iteration: 453199532, states[0] = -23.541137, states[40]= 0.000174
Saving checkpoint... 
Iteration: 462543468, states[0] = -84.660694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 473015216, states[0] = 0.214045, states[40]= 0.000214
Saving checkpoint... 
Iteration: 483575419, states[0] = -27.863827, states[40]= 0.000112
Saving checkpoint... 
Iteration: 493828637, states[0] = -84.353900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503402663, states[0] = -84.769411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510917426, states[0] = 27.565879, states[40]= 0.000054
Saving checkpoint... 
Iteration: 518927895, states[0] = -84.769555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 527348859, states[0] = 3.165896, states[40]= 0.000165
Saving checkpoint... 
Iteration: 536758782, states[0] = -84.783323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548374841, states[0] = -38.153479, states[40]= 0.000106
Saving checkpoint... 
Iteration: 558490026, states[0] = -84.063775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569387916, states[0] = -68.459289, states[40]= 0.000003
Saving checkpoint... 
Iteration: 578923961, states[0] = -84.312581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587335388, states[0] = -84.717844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597643095, states[0] = -84.534905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607561107, states[0] = 3.350372, states[40]= 0.000161
Saving checkpoint... 
Iteration: 618330441, states[0] = -84.455919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627835817, states[0] = -84.562690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637940898, states[0] = -84.733348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647989270, states[0] = -84.686930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658979333, states[0] = 27.814230, states[40]= 0.000066
Saving checkpoint... 
Iteration: 668779782, states[0] = 15.161576, states[40]= 0.000028
Saving checkpoint... 
Iteration: 678629903, states[0] = -58.212830, states[40]= 0.000011
Saving checkpoint... 
Iteration: 686627902, states[0] = 0.068376, states[40]= 0.000216
Saving checkpoint... 
Iteration: 695239947, states[0] = 9.146674, states[40]= 0.000077
Saving checkpoint... 
Iteration: 705077375, states[0] = -55.209712, states[40]= 0.000017
Saving checkpoint... 
Iteration: 715436687, states[0] = -66.797127, states[40]= 0.000004
Saving checkpoint... 
Iteration: 726941307, states[0] = -73.033199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736532516, states[0] = -84.659005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745327986, states[0] = -55.925790, states[40]= 0.000015
Saving checkpoint... 
Iteration: 755497937, states[0] = -84.618173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766008587, states[0] = -33.921284, states[40]= 0.000143
Saving checkpoint... 
Iteration: 776022649, states[0] = 12.067178, states[40]= 0.000048
Saving checkpoint... 
Iteration: 786139219, states[0] = -40.248172, states[40]= 0.000089
Saving checkpoint... 
Iteration: 794960464, states[0] = 30.154012, states[40]= 0.000621
Saving checkpoint... 
Iteration: 805060806, states[0] = 11.677102, states[40]= 0.000052
Saving checkpoint... 
Iteration: 814570985, states[0] = -4.933183, states[40]= 0.000270
Saving checkpoint... 
Iteration: 824040601, states[0] = 8.737427, states[40]= 0.000082
Saving checkpoint... 
Iteration: 833526160, states[0] = 9.947959, states[40]= 0.000068
Saving checkpoint... 
Iteration: 843132652, states[0] = -84.271471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852561774, states[0] = -51.606966, states[40]= 0.000026
Saving checkpoint... 
Iteration: 863964322, states[0] = 28.814147, states[40]= 0.000159
Saving checkpoint... 
Iteration: 873325125, states[0] = -84.313852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882739871, states[0] = -40.974576, states[40]= 0.000083
Saving checkpoint... 
Iteration: 892908042, states[0] = -84.540069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 903260916, states[0] = -84.555277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909998070, states[0] = 11.819101, states[40]= 0.000050
Saving checkpoint... 
Iteration: 920647860, states[0] = 3.892495, states[40]= 0.000152
Saving checkpoint... 
Iteration: 931148188, states[0] = -84.553265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940482144, states[0] = 6.111941, states[40]= 0.000117
Saving checkpoint... 
Iteration: 950262036, states[0] = 2.677612, states[40]= 0.000173
Saving checkpoint... 
Iteration: 960222204, states[0] = -84.705010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969921185, states[0] = -84.276976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979988753, states[0] = -84.320177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988884475, states[0] = -84.160330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997555309, states[0] = -84.521730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008933989, states[0] = -19.914366, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1018665658, states[0] = 16.071740, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1029291003, states[0] = 22.447736, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1039160072, states[0] = -64.645362, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1048792318, states[0] = -84.759278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059645073, states[0] = -84.457275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067962368, states[0] = -84.305991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077457704, states[0] = -84.368894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086966421, states[0] = -84.511146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1096784474, states[0] = -84.700370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1105288104, states[0] = -68.667449, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1114142263, states[0] = -1.478879, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1123848670, states[0] = 31.168184, states[40]= 0.042163
Saving checkpoint... 
Iteration: 1133851359, states[0] = -84.622323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144253436, states[0] = 32.499506, states[40]= 0.652138
Saving checkpoint... 
Iteration: 1155826091, states[0] = 1.509489, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1166100097, states[0] = -72.817514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176023825, states[0] = -80.936308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186062929, states[0] = -52.919085, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1195520961, states[0] = -19.274107, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1205458585, states[0] = -84.694375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215482815, states[0] = -84.529511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1225990197, states[0] = -12.329324, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1235253389, states[0] = -82.956942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246704611, states[0] = -29.383416, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1255239180, states[0] = 31.583892, states[40]= 0.014298
Saving checkpoint... 
Iteration: 1264187465, states[0] = 17.816808, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1273496421, states[0] = -83.784295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282680470, states[0] = -75.140382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293798137, states[0] = 18.792449, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1303883759, states[0] = 5.020725, states[40]= 0.000134
Saving checkpoint... 
Iteration: 1313013132, states[0] = 31.228033, states[40]= 0.097230
Saving checkpoint... 
Iteration: 1321435439, states[0] = -6.925939, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1330207678, states[0] = -84.589039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339807580, states[0] = 13.576341, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1348096040, states[0] = 30.382572, states[40]= 0.108277
Saving checkpoint... 
Iteration: 1357774768, states[0] = -84.394796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367788327, states[0] = -82.040977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378471433, states[0] = -84.369490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387560437, states[0] = -6.921567, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1397702718, states[0] = -84.042338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406437144, states[0] = -84.735923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416852395, states[0] = 16.497465, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1427617419, states[0] = -84.229251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436756491, states[0] = -45.576633, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1446743996, states[0] = 20.946464, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1457563632, states[0] = -84.553422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467488943, states[0] = -10.842119, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1476146381, states[0] = -48.275917, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1484334557, states[0] = -84.689577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492892918, states[0] = -84.338970, states[40]= 0.000000
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.640207
 - CaMKt in component CaMK (millimolar): 0.056329
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.908717
 - nass in component intracellular_ions (millimolar): 6.908893
 - ki in component intracellular_ions (millimolar): 144.673532
 - kss in component intracellular_ions (millimolar): 144.673502
 - cansr in component intracellular_ions (millimolar): 2.234100
 - cajsr in component intracellular_ions (millimolar): 1.849084
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010166
 - hf in component INa (dimensionless): 0.575988
 - hs in component INa (dimensionless): 0.575748
 - j in component INa (dimensionless): 0.574393
 - hsp in component INa (dimensionless): 0.328356
 - jp in component INa (dimensionless): 0.572879
 - mL in component INaL (dimensionless): 0.000348
 - hL in component INaL (dimensionless): 0.321873
 - hLp in component INaL (dimensionless): 0.137065
 - a in component Ito (dimensionless): 0.001245
 - iF in component Ito (dimensionless): 0.999213
 - iS in component Ito (dimensionless): 0.305413
 - ap in component Ito (dimensionless): 0.000635
 - iFp in component Ito (dimensionless): 0.999213
 - iSp in component Ito (dimensionless): 0.336126
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.812794
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990369
 - jca in component ICaL (dimensionless): 0.994303
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007769
 - xrf in component IKr (dimensionless): 0.001968
 - xrs in component IKr (dimensionless): 0.726808
 - xs1 in component IKs (dimensionless): 0.426166
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996768
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:22:00 (25764): called boinc_finish(0)

</stderr_txt>
]]>


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