𝕏

Task 56132199

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_241_1
Workunit 26657712
Created 4 Jul 2024, 21:00:05 UTC
Sent 5 Jul 2024, 2:12:15 UTC
Report deadline 8 Jul 2024, 2:12:15 UTC
Received 8 Jul 2024, 1:44:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 30 sec
CPU time 38 min 46 sec
Validate state Valid
Credit 44.58
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.55 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_241.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_241_1_r257135877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_241_1_r257135877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.734094
     * GNaL_b in INaL: 0.005785
     * Gto_b in Ito: 0.084062
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031950
     * GKs_b in IKs: 0.000096
     * GK1_b in IK1: 0.163757
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.116372
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033076
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11565285, states[0] = 11.371966, states[40]= 0.004505
Saving checkpoint... 
Iteration: 22279080, states[0] = -94.748790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31975431, states[0] = -94.893676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40646728, states[0] = -54.339548, states[40]= 0.000051
Saving checkpoint... 
Iteration: 50094765, states[0] = -4.693113, states[40]= 0.003922
Saving checkpoint... 
Iteration: 59406259, states[0] = -94.857120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69476025, states[0] = -94.881720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80334065, states[0] = -94.798788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90418850, states[0] = -94.860047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97866504, states[0] = -94.827871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108296749, states[0] = -94.746876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116946784, states[0] = -94.870059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126291682, states[0] = -94.737807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136419529, states[0] = -94.858745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146183003, states[0] = -94.006322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154821306, states[0] = -94.781167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163933597, states[0] = -94.864340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173988951, states[0] = -94.880905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181431459, states[0] = -94.863329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190403079, states[0] = -94.849971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198658221, states[0] = -66.457484, states[40]= 0.000007
Saving checkpoint... 
Iteration: 207798821, states[0] = -94.748764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215583652, states[0] = 3.030132, states[40]= 0.004825
Saving checkpoint... 
Iteration: 224184136, states[0] = -94.121531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232804885, states[0] = -94.758031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241494245, states[0] = -94.881641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251061872, states[0] = 13.614112, states[40]= 0.003821
Saving checkpoint... 
Iteration: 261280364, states[0] = -94.715770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270245585, states[0] = -94.632754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282094311, states[0] = -4.092163, states[40]= 0.004052
Saving checkpoint... 
Iteration: 292538536, states[0] = 22.345218, states[40]= 0.002068
Saving checkpoint... 
Iteration: 302886483, states[0] = -94.839683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312816735, states[0] = -94.774372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320086588, states[0] = 1.260424, states[40]= 0.004758
Saving checkpoint... 
Iteration: 329599247, states[0] = -8.158669, states[40]= 0.003145
Saving checkpoint... 
Iteration: 338624690, states[0] = -31.769432, states[40]= 0.000979
Saving checkpoint... 
Iteration: 348087831, states[0] = 0.472533, states[40]= 0.004701
Saving checkpoint... 
Iteration: 355535756, states[0] = 23.271616, states[40]= 0.001916
Saving checkpoint... 
Iteration: 366298707, states[0] = -94.747899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376372051, states[0] = -94.829462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386096869, states[0] = -6.135317, states[40]= 0.003616
Saving checkpoint... 
Iteration: 392871457, states[0] = -94.828956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401800624, states[0] = -94.750801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412116448, states[0] = -24.155999, states[40]= 0.001329
Saving checkpoint... 
Iteration: 420500468, states[0] = -33.213934, states[40]= 0.000026
Saving checkpoint... 
Iteration: 432313269, states[0] = -94.769239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442823654, states[0] = -94.782665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451981239, states[0] = -94.877873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461120909, states[0] = -28.267310, states[40]= 0.001214
Saving checkpoint... 
Iteration: 470947656, states[0] = -94.868097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480301033, states[0] = -94.751133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489245661, states[0] = -94.632098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498354407, states[0] = -94.814661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508903107, states[0] = -94.848641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519627330, states[0] = -34.235077, states[40]= 0.000785
Saving checkpoint... 
Iteration: 530097434, states[0] = -6.605239, states[40]= 0.003509
Saving checkpoint... 
Iteration: 540498559, states[0] = -94.881336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550330004, states[0] = -94.789775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560020264, states[0] = 27.336699, states[40]= 0.002740
Saving checkpoint... 
Iteration: 569456374, states[0] = -94.870565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578430139, states[0] = -94.861111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589675183, states[0] = -90.747917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599941310, states[0] = -94.865349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609622592, states[0] = -29.821820, states[40]= 0.001121
Saving checkpoint... 
Iteration: 620111909, states[0] = -19.937995, states[40]= 0.001380
Saving checkpoint... 
Iteration: 630766821, states[0] = -94.685697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639651299, states[0] = -58.491179, states[40]= 0.000027
Saving checkpoint... 
Iteration: 649710775, states[0] = -94.511758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658403169, states[0] = -94.848090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667997843, states[0] = -94.880695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679366229, states[0] = -94.823836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690086390, states[0] = 1.384597, states[40]= 0.004765
Saving checkpoint... 
Iteration: 699507173, states[0] = 28.655869, states[40]= 0.125585
Saving checkpoint... 
Iteration: 709877660, states[0] = -94.832193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718607628, states[0] = -15.897815, states[40]= 0.001671
Saving checkpoint... 
Iteration: 728794762, states[0] = -94.740014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738116571, states[0] = -24.268250, states[40]= 0.001328
Saving checkpoint... 
Iteration: 748120553, states[0] = -27.937792, states[40]= 0.001231
Saving checkpoint... 
Iteration: 758811118, states[0] = -94.764978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769691574, states[0] = -94.402229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779822315, states[0] = -94.779691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788593716, states[0] = -3.635638, states[40]= 0.004140
Saving checkpoint... 
Iteration: 798509126, states[0] = 28.076590, states[40]= 0.065451
Saving checkpoint... 
Iteration: 809091324, states[0] = -1.883385, states[40]= 0.004432
Saving checkpoint... 
Iteration: 820392306, states[0] = -94.841269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830541008, states[0] = 21.497182, states[40]= 0.002220
Saving checkpoint... 
Iteration: 841305199, states[0] = -94.756086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851482619, states[0] = -94.876645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861542988, states[0] = 20.803381, states[40]= 0.002350
Saving checkpoint... 
Iteration: 871298132, states[0] = -94.744992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880632622, states[0] = -39.267050, states[40]= 0.000445
Saving checkpoint... 
Iteration: 890966760, states[0] = -94.872391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901091966, states[0] = -2.341704, states[40]= 0.004363
Saving checkpoint... 
Iteration: 912146738, states[0] = -53.601275, states[40]= 0.000058
Saving checkpoint... 
Iteration: 922964584, states[0] = -94.871648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933122512, states[0] = -29.746521, states[40]= 0.001126
Saving checkpoint... 
Iteration: 943210293, states[0] = -94.508660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953183016, states[0] = -93.999901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961885800, states[0] = -94.836668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972590062, states[0] = -1.005418, states[40]= 0.004550
Saving checkpoint... 
Iteration: 983051714, states[0] = 17.621071, states[40]= 0.003004
Saving checkpoint... 
Iteration: 993074163, states[0] = 8.091643, states[40]= 0.004614
Saving checkpoint... 
Iteration: 1002292335, states[0] = -94.734825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012031370, states[0] = 24.651608, states[40]= 0.001724
Saving checkpoint... 
Iteration: 1021879131, states[0] = -94.831995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031882836, states[0] = -94.834459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043302222, states[0] = -94.750772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054537444, states[0] = 22.714029, states[40]= 0.002006
Saving checkpoint... 
Iteration: 1064274986, states[0] = -94.701749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072965003, states[0] = -94.871183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083210882, states[0] = -94.510468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093415437, states[0] = -94.852607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104070319, states[0] = 9.921716, states[40]= 0.004410
Saving checkpoint... 
Iteration: 1112757305, states[0] = -94.660986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122072801, states[0] = 8.752497, states[40]= 0.004547
Saving checkpoint... 
Iteration: 1131304441, states[0] = -94.753811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141614092, states[0] = -21.972619, states[40]= 0.001343
Saving checkpoint... 
Iteration: 1151056750, states[0] = 15.684732, states[40]= 0.003412
Saving checkpoint... 
Iteration: 1161135007, states[0] = -41.590497, states[40]= 0.000331
Saving checkpoint... 
Iteration: 1170422369, states[0] = -94.855490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178372105, states[0] = -94.826368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186859359, states[0] = -94.816256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197585400, states[0] = 1.993469, states[40]= 0.004796
Saving checkpoint... 
Iteration: 1208789576, states[0] = -94.729201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219258443, states[0] = -94.663422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229106553, states[0] = -14.877814, states[40]= 0.001802
Saving checkpoint... 
Iteration: 1238385050, states[0] = -94.835104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247243161, states[0] = -94.621848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255737989, states[0] = -94.606169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265984689, states[0] = -94.875515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277473349, states[0] = -94.872671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288220256, states[0] = -94.545729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297575350, states[0] = 7.504664, states[40]= 0.004666
Saving checkpoint... 
Iteration: 1306874122, states[0] = -94.827343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315012098, states[0] = 27.968958, states[40]= 0.024556
Saving checkpoint... 
Iteration: 1324940503, states[0] = -94.862225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333832738, states[0] = -94.789798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343787243, states[0] = -94.724486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354767071, states[0] = -94.683416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365337921, states[0] = -94.795295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376438154, states[0] = -94.861149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385514660, states[0] = 27.919850, states[40]= 0.010953
Saving checkpoint... 
Iteration: 1395308202, states[0] = -94.758330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404905243, states[0] = -94.846282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414856874, states[0] = -94.813241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424948796, states[0] = -94.864764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432436151, states[0] = -94.860167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443772739, states[0] = -94.695528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453375860, states[0] = -94.828019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462920139, states[0] = -94.853349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472499747, states[0] = -94.877939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480091266, states[0] = -1.840653, states[40]= 0.004439
Saving checkpoint... 
Iteration: 1489599700, states[0] = -8.552285, states[40]= 0.003052
Saving checkpoint... 
Iteration: 1499518305, states[0] = 27.618698, states[40]= 0.004067
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.753758
 - CaMKt in component CaMK (millimolar): 0.012921
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.744901
 - nass in component intracellular_ions (millimolar): 6.744997
 - ki in component intracellular_ions (millimolar): 145.136042
 - kss in component intracellular_ions (millimolar): 145.136021
 - cansr in component intracellular_ions (millimolar): 1.670291
 - cajsr in component intracellular_ions (millimolar): 1.627948
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003673
 - hf in component INa (dimensionless): 0.877407
 - hs in component INa (dimensionless): 0.877399
 - j in component INa (dimensionless): 0.877348
 - hsp in component INa (dimensionless): 0.720941
 - jp in component INa (dimensionless): 0.877313
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.702197
 - hLp in component INaL (dimensionless): 0.437129
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.606235
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.676141
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.912009
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999814
 - jca in component ICaL (dimensionless): 0.999969
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003083
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.372890
 - xs1 in component IKs (dimensionless): 0.275703
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:44:37 (24340): called boinc_finish(0)

</stderr_txt>
]]>


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