𝕏

Task 56131589

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_3000-conf_741_0
Workunit 26657408
Created 4 Jul 2024, 20:59:49 UTC
Sent 5 Jul 2024, 2:12:15 UTC
Report deadline 8 Jul 2024, 2:12:15 UTC
Received 8 Jul 2024, 1:54:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 47 sec
CPU time 39 min 3 sec
Validate state Valid
Credit 45.12
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.58 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_3000-conf_741.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_3000-conf_741_0_r1714438456_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_EPI_3000-conf_741_0_r1714438456_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.873533
     * GNaL_b in INaL: 0.005864
     * Gto_b in Ito: 0.084281
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031789
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.164056
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.677158
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032815
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11371605, states[0] = -94.385300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21011692, states[0] = 21.517693, states[40]= 0.000882
Saving checkpoint... 
Iteration: 29140155, states[0] = -94.328556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37790817, states[0] = -94.077451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47003661, states[0] = -94.305128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57642837, states[0] = -94.321957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66400522, states[0] = -94.260958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75146113, states[0] = -42.094382, states[40]= 0.000238
Saving checkpoint... 
Iteration: 83911683, states[0] = -94.301846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92629920, states[0] = -94.314593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102951515, states[0] = -94.325130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111695321, states[0] = -94.337198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120580739, states[0] = -94.335821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128443779, states[0] = -94.329192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136744115, states[0] = -93.905483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145719213, states[0] = -93.755000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155598368, states[0] = -94.323727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163122905, states[0] = -94.322904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170497190, states[0] = -94.328765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177739318, states[0] = -94.340497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186717605, states[0] = -94.341176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196736659, states[0] = -93.866283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207014724, states[0] = 22.853578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216883949, states[0] = -94.334367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227007625, states[0] = -94.328108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236115755, states[0] = -94.340773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246100892, states[0] = 2.153635, states[40]= 0.000151
Saving checkpoint... 
Iteration: 254373983, states[0] = -94.334423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262727347, states[0] = -93.809400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270543115, states[0] = -94.334134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279523023, states[0] = -94.330652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290162116, states[0] = -94.340863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299767972, states[0] = -94.316322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309238038, states[0] = -93.872781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316798720, states[0] = -94.116150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327376875, states[0] = -94.253755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337392438, states[0] = -94.311430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346868821, states[0] = -94.244322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357809482, states[0] = -94.335742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368807321, states[0] = -94.313750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378977047, states[0] = -94.327411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389401793, states[0] = -94.330884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397517847, states[0] = 23.838042, states[40]= -0.000000
Saving checkpoint... 
Iteration: 406697526, states[0] = -93.575836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416701832, states[0] = -94.316864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426005613, states[0] = 15.816891, states[40]= -0.000002
Saving checkpoint... 
Iteration: 436070072, states[0] = -94.322099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447214535, states[0] = -93.719528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458295839, states[0] = -94.334612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467567787, states[0] = -94.321661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476385322, states[0] = -94.330190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485728039, states[0] = -94.314662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493960001, states[0] = -94.308736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505939830, states[0] = -94.299100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516058884, states[0] = 22.163006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525493342, states[0] = -94.319609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535937153, states[0] = -94.297156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547150025, states[0] = -94.316730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557137397, states[0] = -94.336086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566709968, states[0] = -94.313972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576234242, states[0] = -93.846189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586089416, states[0] = -94.318666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595376803, states[0] = -94.307521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606620100, states[0] = -94.334789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617364199, states[0] = -94.328794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628018489, states[0] = -94.321182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636812890, states[0] = -94.330822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646928435, states[0] = -94.290292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656435886, states[0] = -94.324650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665794495, states[0] = -94.309113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677380151, states[0] = -94.326997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686270628, states[0] = -94.331721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696424610, states[0] = -94.287105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706536726, states[0] = 26.058925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716144948, states[0] = -94.333491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724885271, states[0] = -94.255578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736131220, states[0] = -94.314288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747385711, states[0] = -94.255621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756733566, states[0] = -94.331785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766593103, states[0] = 6.994398, states[40]= 0.000069
Saving checkpoint... 
Iteration: 776559097, states[0] = -94.316767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785514659, states[0] = -94.318669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794919465, states[0] = -94.302752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803252951, states[0] = -94.330372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813409878, states[0] = -94.275079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824286668, states[0] = -94.328735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834031391, states[0] = 26.012567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844615652, states[0] = -10.189370, states[40]= 0.000300
Saving checkpoint... 
Iteration: 853227523, states[0] = -94.308386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862001218, states[0] = -94.317991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871442001, states[0] = -94.300748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881700132, states[0] = -94.308966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892998277, states[0] = -94.314654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904154258, states[0] = -94.310445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913745124, states[0] = -93.900630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923038583, states[0] = -94.322370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933306289, states[0] = -94.125093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942990730, states[0] = -94.317104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954220981, states[0] = -93.755490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963998467, states[0] = -94.316375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973447909, states[0] = -94.298821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983061703, states[0] = -94.324368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993057759, states[0] = 22.499201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003290200, states[0] = -94.303489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012691189, states[0] = -93.393774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023729664, states[0] = -94.327333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031159338, states[0] = -94.328222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040700359, states[0] = -94.306232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049519922, states[0] = -94.313898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060234712, states[0] = -94.304562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068412007, states[0] = -94.272256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077680538, states[0] = -94.327361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087692241, states[0] = -93.441513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097629583, states[0] = -94.308162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107897248, states[0] = -94.318808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117729829, states[0] = -93.809958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128175193, states[0] = -81.575658, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1137978204, states[0] = -94.314364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145803262, states[0] = -94.300579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155640764, states[0] = -94.325911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163803520, states[0] = -94.300260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172478270, states[0] = -94.313767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183014109, states[0] = -94.311883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193533050, states[0] = -94.310817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202925850, states[0] = -94.295554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212574471, states[0] = -94.321708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223245882, states[0] = -94.323422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233078261, states[0] = 14.683638, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1243290330, states[0] = -94.299372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253119047, states[0] = -94.323698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263099666, states[0] = 2.973560, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1274283588, states[0] = -94.321162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285077771, states[0] = -94.307218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294276106, states[0] = -94.299013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302927405, states[0] = -94.314006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313495648, states[0] = -94.310531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322501070, states[0] = -94.310119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330616754, states[0] = -11.315204, states[40]= 0.000295
Saving checkpoint... 
Iteration: 1339399061, states[0] = -94.294057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348042348, states[0] = -94.307748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359294592, states[0] = -94.086618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369209124, states[0] = -94.300260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379123586, states[0] = -94.321692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389551444, states[0] = -94.316201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397072422, states[0] = -94.318371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408267062, states[0] = -94.297392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417881653, states[0] = -94.240056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427239563, states[0] = -94.320139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435958926, states[0] = -94.292157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447276133, states[0] = -94.296388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457504219, states[0] = -94.307655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468049421, states[0] = -94.305367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478045803, states[0] = -94.313932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487158209, states[0] = -94.320419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497833389, states[0] = -94.315173, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.164237
 - CaMKt in component CaMK (millimolar): 0.003679
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.230494
 - nass in component intracellular_ions (millimolar): 7.230634
 - ki in component intracellular_ions (millimolar): 144.394979
 - kss in component intracellular_ions (millimolar): 144.394961
 - cansr in component intracellular_ions (millimolar): 2.469080
 - cajsr in component intracellular_ions (millimolar): 2.469748
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003898
 - hf in component INa (dimensionless): 0.866600
 - hs in component INa (dimensionless): 0.866601
 - j in component INa (dimensionless): 0.866608
 - hsp in component INa (dimensionless): 0.701097
 - jp in component INa (dimensionless): 0.866612
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709361
 - hLp in component INaL (dimensionless): 0.513336
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991097
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005332
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024943
 - xs1 in component IKs (dimensionless): 0.069191
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997524
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:53:55 (24438): called boinc_finish(0)

</stderr_txt>
]]>


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