𝕏

Task 56131359

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_341_0
Workunit 26657293
Created 4 Jul 2024, 20:59:39 UTC
Sent 5 Jul 2024, 2:09:33 UTC
Report deadline 8 Jul 2024, 2:09:33 UTC
Received 7 Jul 2024, 22:59:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min
CPU time 38 min 4 sec
Validate state Valid
Credit 45.77
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.39 MB
Peak swap size 391.75 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_341.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_341_0_r1191005339_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_5000-conf_341_0_r1191005339_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.852406
     * GNaL_b in INaL: 0.005841
     * Gto_b in Ito: 0.085183
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031751
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.163589
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.360902
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032467
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10664981, states[0] = -94.664944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18833508, states[0] = -94.606949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30143376, states[0] = -35.950793, states[40]= 0.000633
Saving checkpoint... 
Iteration: 40889624, states[0] = -94.538939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52653113, states[0] = -41.882753, states[40]= 0.000330
Saving checkpoint... 
Iteration: 60979643, states[0] = -94.511034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69576255, states[0] = -94.489114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79962284, states[0] = -94.480808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88360051, states[0] = -94.496494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98751197, states[0] = -94.486120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107137348, states[0] = -94.473387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116571361, states[0] = -94.476917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127455487, states[0] = -94.467894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139206245, states[0] = -94.472159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150399830, states[0] = -94.401304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159370915, states[0] = -94.468851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167168393, states[0] = -94.466071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175469862, states[0] = -94.441241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185178004, states[0] = -61.379555, states[40]= 0.000016
Saving checkpoint... 
Iteration: 195572592, states[0] = -94.468959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205774205, states[0] = -94.482562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216411584, states[0] = -94.472599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223917700, states[0] = -94.472392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234237671, states[0] = -94.468028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243729698, states[0] = -94.475490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254172307, states[0] = -94.468597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262727243, states[0] = -94.050443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272585024, states[0] = 8.488762, states[40]= 0.004464
Saving checkpoint... 
Iteration: 282840597, states[0] = -94.334878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294621918, states[0] = -94.464311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304715137, states[0] = -94.463666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314297941, states[0] = -94.466992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324147904, states[0] = -94.468635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332477579, states[0] = -94.462166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342097404, states[0] = -94.464387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352323343, states[0] = -94.462938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363296180, states[0] = -94.481840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373793277, states[0] = -94.473902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383738490, states[0] = -94.474913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394020723, states[0] = -94.470213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403609762, states[0] = -94.477449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413107785, states[0] = -94.472764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421785133, states[0] = -94.466993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431973796, states[0] = -94.465247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443043428, states[0] = -94.462184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452379254, states[0] = -94.462542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463277691, states[0] = -94.481617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472732010, states[0] = -94.069142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481723683, states[0] = -94.467602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491441698, states[0] = -94.471306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500890861, states[0] = -94.481300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509058578, states[0] = -94.469601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519438655, states[0] = -94.465478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529731391, states[0] = -94.463333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539200702, states[0] = -94.467818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549129589, states[0] = -94.468655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559390481, states[0] = -94.465874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570166816, states[0] = -51.145669, states[40]= 0.000087
Saving checkpoint... 
Iteration: 581442647, states[0] = -94.471227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590950249, states[0] = -94.480382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601646824, states[0] = -94.468406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611142110, states[0] = -94.476641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621408747, states[0] = -94.471734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632676325, states[0] = -59.688016, states[40]= 0.000021
Saving checkpoint... 
Iteration: 644278597, states[0] = -94.466899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655205643, states[0] = -92.595790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665359977, states[0] = -94.359225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673827432, states[0] = -94.473066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683385373, states[0] = -94.481233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693555965, states[0] = -94.478327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703977027, states[0] = -94.470619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714330558, states[0] = -94.466328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725084851, states[0] = 8.569728, states[40]= 0.004460
Saving checkpoint... 
Iteration: 735485756, states[0] = -94.445447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744330116, states[0] = -94.466311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753915829, states[0] = -94.471527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762672671, states[0] = -56.351166, states[40]= 0.000037
Saving checkpoint... 
Iteration: 772869612, states[0] = -94.369847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783064266, states[0] = -94.466078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792550094, states[0] = 21.029991, states[40]= 0.002609
Saving checkpoint... 
Iteration: 802232307, states[0] = -94.463134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812600440, states[0] = 0.780758, states[40]= 0.004435
Saving checkpoint... 
Iteration: 822625450, states[0] = -17.402654, states[40]= 0.001495
Saving checkpoint... 
Iteration: 832682613, states[0] = -65.824955, states[40]= 0.000007
Saving checkpoint... 
Iteration: 842499403, states[0] = -94.461665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852785612, states[0] = -94.232421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862134765, states[0] = -94.463728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871459664, states[0] = -94.470761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882227109, states[0] = -94.463110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893237622, states[0] = -94.480644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903541560, states[0] = -94.478467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911613177, states[0] = -94.468604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921343473, states[0] = -94.472611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931088021, states[0] = -94.477512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940967681, states[0] = -94.479837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952155988, states[0] = -94.463520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961933529, states[0] = -94.465209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972048661, states[0] = -94.464271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981286293, states[0] = -94.473587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990566264, states[0] = -94.466288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999457760, states[0] = -94.464976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010191160, states[0] = -76.042767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020995503, states[0] = -94.479275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032079805, states[0] = -94.463997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042188458, states[0] = -94.463242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050978523, states[0] = -94.479566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060370670, states[0] = -94.370759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071739173, states[0] = -94.467014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082228413, states[0] = -94.462960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092798801, states[0] = -94.261927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100811067, states[0] = -94.481348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109600952, states[0] = -94.463790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119540333, states[0] = -94.464230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129707920, states[0] = -94.463055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139960126, states[0] = -94.461642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151102222, states[0] = -94.477068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161711084, states[0] = -94.467261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170898066, states[0] = -94.480740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179765978, states[0] = -94.462663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188994124, states[0] = -94.470025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199191346, states[0] = -94.467458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209229775, states[0] = -94.467020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221625266, states[0] = -94.468233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231733055, states[0] = -94.466968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241551202, states[0] = -94.469183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250384988, states[0] = -94.384689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260396034, states[0] = -94.394318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269975010, states[0] = -94.461478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281677369, states[0] = -94.467562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290606678, states[0] = -94.472008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301887111, states[0] = -94.465380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311388762, states[0] = -94.471572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321996000, states[0] = -94.464435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331923687, states[0] = -94.465033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340178080, states[0] = -61.335017, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1347446126, states[0] = -94.461564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357308075, states[0] = -94.462291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366778419, states[0] = -94.466390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376381835, states[0] = -94.471640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384842780, states[0] = -94.462077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395437350, states[0] = -94.422705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406681390, states[0] = -94.467427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415928173, states[0] = -94.480151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423440822, states[0] = -94.479948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432692283, states[0] = -77.628810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441535173, states[0] = -94.469262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450365866, states[0] = -94.365322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460826784, states[0] = -94.481088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471784257, states[0] = -94.466256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481357685, states[0] = -94.471972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490409284, states[0] = -94.404486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499800604, states[0] = -94.462234, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.337172
 - CaMKt in component CaMK (millimolar): 0.001125
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.309646
 - nass in component intracellular_ions (millimolar): 6.309732
 - ki in component intracellular_ions (millimolar): 145.615630
 - kss in component intracellular_ions (millimolar): 145.615619
 - cansr in component intracellular_ions (millimolar): 1.566261
 - cajsr in component intracellular_ions (millimolar): 1.566299
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003831
 - hf in component INa (dimensionless): 0.869851
 - hs in component INa (dimensionless): 0.869851
 - j in component INa (dimensionless): 0.869852
 - hsp in component INa (dimensionless): 0.707011
 - jp in component INa (dimensionless): 0.869852
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714028
 - hLp in component INaL (dimensionless): 0.521674
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997754
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999256
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998864
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002993
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001784
 - xs1 in component IKs (dimensionless): 0.022811
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997482
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:20:08 (21313): called boinc_finish(0)

</stderr_txt>
]]>


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