𝕏

Task 56131318

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_241_1
Workunit 26657272
Created 4 Jul 2024, 20:59:39 UTC
Sent 5 Jul 2024, 2:09:33 UTC
Report deadline 8 Jul 2024, 2:09:33 UTC
Received 8 Jul 2024, 1:04:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 1 sec
CPU time 38 min 35 sec
Validate state Valid
Credit 44.99
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.75 MB
Peak swap size 391.75 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_241.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_241_1_r459843487_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_1000-conf_241_1_r459843487_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.734094
     * GNaL_b in INaL: 0.005785
     * Gto_b in Ito: 0.084062
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031950
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163757
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.116372
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033076
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10961917, states[0] = -94.982205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20216372, states[0] = -94.630416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29266273, states[0] = -94.751358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38231502, states[0] = -94.647665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49581243, states[0] = 2.287097, states[40]= 0.004644
Saving checkpoint... 
Iteration: 60222597, states[0] = -94.608715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71310784, states[0] = -94.813196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82132876, states[0] = -45.004089, states[40]= 0.000187
Saving checkpoint... 
Iteration: 91942788, states[0] = -94.911494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101740858, states[0] = -94.665399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111864166, states[0] = -94.867623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122024057, states[0] = 26.187817, states[40]= 0.001742
Saving checkpoint... 
Iteration: 130876479, states[0] = -94.876365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141283705, states[0] = -94.766488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151038541, states[0] = 21.707102, states[40]= 0.002018
Saving checkpoint... 
Iteration: 160343904, states[0] = -94.848821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169634553, states[0] = -46.612485, states[40]= 0.000150
Saving checkpoint... 
Iteration: 180053146, states[0] = 16.141185, states[40]= 0.003080
Saving checkpoint... 
Iteration: 191384844, states[0] = -94.881325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202131551, states[0] = -43.522968, states[40]= 0.000229
Saving checkpoint... 
Iteration: 210811114, states[0] = -94.810073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220507693, states[0] = 28.196832, states[40]= 0.105880
Saving checkpoint... 
Iteration: 230523666, states[0] = 26.285737, states[40]= 0.001788
Saving checkpoint... 
Iteration: 240059261, states[0] = 13.592889, states[40]= 0.003581
Saving checkpoint... 
Iteration: 251388400, states[0] = -94.883265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262003715, states[0] = 34.842119, states[40]= 0.381420
Saving checkpoint... 
Iteration: 272861573, states[0] = -94.864004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283697312, states[0] = -94.499502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294157212, states[0] = -72.606581, states[40]= 0.000002
Saving checkpoint... 
Iteration: 304374247, states[0] = -94.873584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313791293, states[0] = -94.779002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324969261, states[0] = -94.917240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333946910, states[0] = -94.910351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342802237, states[0] = -94.796594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353100138, states[0] = -12.873900, states[40]= 0.002085
Saving checkpoint... 
Iteration: 362127987, states[0] = -39.941687, states[40]= 0.000366
Saving checkpoint... 
Iteration: 374016694, states[0] = 27.480781, states[40]= 0.006041
Saving checkpoint... 
Iteration: 386117675, states[0] = -29.950475, states[40]= 0.000983
Saving checkpoint... 
Iteration: 396939847, states[0] = -94.907586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407322332, states[0] = -94.823891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416834111, states[0] = -94.837474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427338520, states[0] = -94.842113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437024084, states[0] = 26.187763, states[40]= 0.001742
Saving checkpoint... 
Iteration: 447330370, states[0] = -94.833208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457003428, states[0] = 36.092848, states[40]= 0.411309
Saving checkpoint... 
Iteration: 467445023, states[0] = -94.909164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475839930, states[0] = -94.843371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486108508, states[0] = -21.140404, states[40]= 0.001252
Saving checkpoint... 
Iteration: 496504706, states[0] = 31.666161, states[40]= 0.283227
Saving checkpoint... 
Iteration: 507053820, states[0] = 15.869781, states[40]= 0.003136
Saving checkpoint... 
Iteration: 516017809, states[0] = 27.355541, states[40]= 0.004517
Saving checkpoint... 
Iteration: 525677033, states[0] = -93.972436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534419414, states[0] = -94.898661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543282257, states[0] = -94.761783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551392862, states[0] = -94.884766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558678038, states[0] = -94.089972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567092885, states[0] = -6.087201, states[40]= 0.003558
Saving checkpoint... 
Iteration: 574755852, states[0] = -94.703605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584047895, states[0] = 18.221260, states[40]= 0.002662
Saving checkpoint... 
Iteration: 593428785, states[0] = -94.902484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600278467, states[0] = -94.754224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608406682, states[0] = -94.892198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617379993, states[0] = -94.876339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626748948, states[0] = -94.685212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636317676, states[0] = -94.817106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647654617, states[0] = -69.038989, states[40]= 0.000004
Saving checkpoint... 
Iteration: 658543810, states[0] = 19.779255, states[40]= 0.002361
Saving checkpoint... 
Iteration: 668643114, states[0] = -55.663671, states[40]= 0.000038
Saving checkpoint... 
Iteration: 679278332, states[0] = -94.753641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688788226, states[0] = -94.772145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697180046, states[0] = -94.244584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706522724, states[0] = 26.499005, states[40]= 0.001930
Saving checkpoint... 
Iteration: 715107065, states[0] = -19.728133, states[40]= 0.001304
Saving checkpoint... 
Iteration: 723793757, states[0] = -94.781530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733924854, states[0] = -94.900269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744343153, states[0] = -94.845539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751997707, states[0] = -94.922235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759974403, states[0] = -94.916871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768265057, states[0] = -94.725012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778525919, states[0] = 25.727784, states[40]= 0.001623
Saving checkpoint... 
Iteration: 790035947, states[0] = 22.622223, states[40]= 0.001874
Saving checkpoint... 
Iteration: 801355488, states[0] = -94.856757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812473795, states[0] = -94.916505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822314328, states[0] = -94.811958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832255992, states[0] = -94.702924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842349212, states[0] = -94.850952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852558431, states[0] = 13.949635, states[40]= 0.003515
Saving checkpoint... 
Iteration: 861739467, states[0] = -94.656939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871209850, states[0] = -94.551728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881201066, states[0] = -94.514282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891679613, states[0] = -94.217144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902294664, states[0] = -94.782324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913891377, states[0] = -94.882433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923555470, states[0] = 15.193319, states[40]= 0.003272
Saving checkpoint... 
Iteration: 932456041, states[0] = -94.910959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942134465, states[0] = -46.507817, states[40]= 0.000152
Saving checkpoint... 
Iteration: 953313211, states[0] = -94.809929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962891521, states[0] = -94.882324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971939935, states[0] = -94.905329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983411901, states[0] = -94.893329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994268041, states[0] = -94.730826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004908461, states[0] = -94.891529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015422149, states[0] = -94.897970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024817486, states[0] = -94.815307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034185034, states[0] = -94.402780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044569238, states[0] = 9.021811, states[40]= 0.004301
Saving checkpoint... 
Iteration: 1054432743, states[0] = -94.902250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064525578, states[0] = 25.816998, states[40]= 0.001637
Saving checkpoint... 
Iteration: 1074682821, states[0] = -94.355419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085130024, states[0] = -41.971935, states[40]= 0.000282
Saving checkpoint... 
Iteration: 1094847976, states[0] = -94.848790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105194783, states[0] = -94.483730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114692102, states[0] = -94.468999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125444285, states[0] = -94.906286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135317241, states[0] = -94.814547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144136960, states[0] = -49.110721, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1153661895, states[0] = -79.879182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1163050123, states[0] = 17.351316, states[40]= 0.002837
Saving checkpoint... 
Iteration: 1173089816, states[0] = -3.544694, states[40]= 0.004066
Saving checkpoint... 
Iteration: 1184494842, states[0] = -94.919929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195842021, states[0] = -94.842611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206108063, states[0] = -20.703632, states[40]= 0.001265
Saving checkpoint... 
Iteration: 1214685335, states[0] = -94.406783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224680150, states[0] = -94.248056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233568567, states[0] = 9.350162, states[40]= 0.004261
Saving checkpoint... 
Iteration: 1242871402, states[0] = -94.867767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253381657, states[0] = -94.874920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262275618, states[0] = -94.745854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274211921, states[0] = -94.558483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285645831, states[0] = -58.621624, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1296583361, states[0] = 1.090247, states[40]= 0.004613
Saving checkpoint... 
Iteration: 1306779772, states[0] = -94.753950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315832387, states[0] = -94.831993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325224873, states[0] = -94.607165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335348706, states[0] = -94.848514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346506647, states[0] = 28.793330, states[40]= 0.150093
Saving checkpoint... 
Iteration: 1357402776, states[0] = -94.887157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366950293, states[0] = -94.907379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376327774, states[0] = -94.826522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384411425, states[0] = -94.891498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394515259, states[0] = 27.601420, states[40]= 0.009105
Saving checkpoint... 
Iteration: 1405152964, states[0] = -66.913928, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1415134229, states[0] = -46.261214, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1423237456, states[0] = -94.648509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432914470, states[0] = -94.892781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442524275, states[0] = 26.143219, states[40]= 0.001724
Saving checkpoint... 
Iteration: 1450954228, states[0] = -94.908323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461196642, states[0] = -94.491513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472450614, states[0] = -94.907065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481460180, states[0] = -94.910040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490601553, states[0] = -14.268129, states[40]= 0.001849
Saving checkpoint... 
Iteration: 1499698663, states[0] = -94.500886, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.795592
 - CaMKt in component CaMK (millimolar): 0.012766
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.750899
 - nass in component intracellular_ions (millimolar): 6.750997
 - ki in component intracellular_ions (millimolar): 145.128816
 - kss in component intracellular_ions (millimolar): 145.128794
 - cansr in component intracellular_ions (millimolar): 1.672664
 - cajsr in component intracellular_ions (millimolar): 1.631110
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878145
 - hs in component INa (dimensionless): 0.878137
 - j in component INa (dimensionless): 0.878086
 - hsp in component INa (dimensionless): 0.722322
 - jp in component INa (dimensionless): 0.878051
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704723
 - hLp in component INaL (dimensionless): 0.442270
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.612258
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.683257
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916714
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999837
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003094
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.364873
 - xs1 in component IKs (dimensionless): 0.266122
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:04:16 (23816): called boinc_finish(0)

</stderr_txt>
]]>


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