𝕏

Task 56127501

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_4000-conf_437_1
Workunit 26655365
Created 4 Jul 2024, 20:57:49 UTC
Sent 5 Jul 2024, 1:44:05 UTC
Report deadline 8 Jul 2024, 1:44:05 UTC
Received 5 Jul 2024, 6:04:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236755
Run time 3 hours 8 min 24 sec
CPU time 3 hours 2 min 18 sec
Validate state Valid
Credit 43.39
Device peak FLOPS 2.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_4000-conf_437.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_4000-conf_437_1_r1266871359_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_MID_4000-conf_437_1_r1266871359_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.985019
     * GNaL_b in INaL: 0.005908
     * Gto_b in Ito: 0.084072
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031734
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163755
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.558727
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032485
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7729280, states[0] = -94.231262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15557051, states[0] = -94.214829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22591421, states[0] = -94.194333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29369619, states[0] = -94.214226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35250140, states[0] = -94.221422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40150224, states[0] = -0.262106, states[40]= 0.000424
Saving checkpoint... 
Iteration: 46263541, states[0] = -52.157700, states[40]= 0.000459
Saving checkpoint... 
Iteration: 53719497, states[0] = -94.222721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61290942, states[0] = -94.239142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68817946, states[0] = -94.256868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76545394, states[0] = -94.215610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84315520, states[0] = -93.775642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91921700, states[0] = -94.239920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99626979, states[0] = -94.247682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107209783, states[0] = -94.261369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114840025, states[0] = -94.273528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122505176, states[0] = -94.207306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131724793, states[0] = -94.252091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141379913, states[0] = -94.261376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 150954459, states[0] = -94.276085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160443621, states[0] = -94.151874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170041476, states[0] = 33.431413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179317070, states[0] = -94.265428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188833389, states[0] = -94.279657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197050290, states[0] = -94.274789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206429854, states[0] = -94.134578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215936378, states[0] = -94.252439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225352897, states[0] = -94.264884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234865595, states[0] = -94.279774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244352277, states[0] = -93.959632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253804530, states[0] = -94.254395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263261053, states[0] = -94.267596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272855867, states[0] = -94.279644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282257266, states[0] = -63.602884, states[40]= 0.000079
Saving checkpoint... 
Iteration: 291705407, states[0] = -94.255875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301284325, states[0] = -94.266501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310902860, states[0] = -94.278608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320383131, states[0] = -94.045865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329900483, states[0] = -94.252171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339465286, states[0] = -94.260814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348871902, states[0] = -94.278687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358533614, states[0] = -94.229898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 368027485, states[0] = 33.945124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377639672, states[0] = -94.256250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 386778618, states[0] = -94.277854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 396055912, states[0] = 30.538862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405306485, states[0] = -94.264618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414504018, states[0] = -94.210806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423689031, states[0] = -94.254697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 432907837, states[0] = -94.277097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442163338, states[0] = -11.248793, states[40]= 0.000722
Saving checkpoint... 
Iteration: 451415055, states[0] = -94.260857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460667504, states[0] = -94.268794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469941452, states[0] = -94.249939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479265485, states[0] = -94.265044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488636644, states[0] = -94.263368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497997042, states[0] = -94.248865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507197195, states[0] = -94.266981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516550552, states[0] = -94.236435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525709959, states[0] = -94.253069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534916393, states[0] = -94.275696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544068043, states[0] = 26.980758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553256694, states[0] = -94.264445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562513465, states[0] = -94.215493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571730125, states[0] = -94.252136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 581084202, states[0] = -94.270014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590330181, states[0] = -93.874046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599586457, states[0] = -94.254763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608851835, states[0] = -94.275791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 618191396, states[0] = -23.578773, states[40]= 0.005374
Saving checkpoint... 
Iteration: 627555001, states[0] = -94.255155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636832608, states[0] = -94.275523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646047719, states[0] = 32.401057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655236753, states[0] = -94.263880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664486856, states[0] = -94.194449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673765758, states[0] = -94.250264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 681993999, states[0] = -94.246699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689790226, states[0] = -94.249644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697580290, states[0] = -94.253729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705237450, states[0] = -94.263259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713092477, states[0] = -94.268147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720891456, states[0] = -94.273965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 728593992, states[0] = -94.250112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736433595, states[0] = -94.134616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744099017, states[0] = 15.972824, states[40]= 0.000012
Saving checkpoint... 
Iteration: 751598939, states[0] = -94.252662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759338584, states[0] = -94.259396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767035575, states[0] = -94.269452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774661039, states[0] = -94.264108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782491530, states[0] = -94.196890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790181026, states[0] = -20.128699, states[40]= 0.002804
Saving checkpoint... 
Iteration: 797914357, states[0] = -94.246391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805531421, states[0] = -94.253586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813183070, states[0] = -94.263802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820769084, states[0] = -94.272392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828386674, states[0] = -94.048021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836097526, states[0] = 16.528676, states[40]= 0.000010
Saving checkpoint... 
Iteration: 843821513, states[0] = -94.247272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851532076, states[0] = -94.253019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858730342, states[0] = -94.270138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866275902, states[0] = -89.481568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873828238, states[0] = -94.246804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881515011, states[0] = -94.253081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889202018, states[0] = -94.262249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896582521, states[0] = -94.244464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904180445, states[0] = -19.907860, states[40]= 0.002649
Saving checkpoint... 
Iteration: 911615008, states[0] = -94.250395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919239742, states[0] = -94.260623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 926971821, states[0] = -94.269564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934819339, states[0] = -94.271927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942512693, states[0] = -94.210425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950188980, states[0] = -22.804687, states[40]= 0.004888
Saving checkpoint... 
Iteration: 957668126, states[0] = -94.248726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965422802, states[0] = -94.254492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972886133, states[0] = -94.271044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980579228, states[0] = -94.242335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988277941, states[0] = -91.346587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 995885230, states[0] = -94.244451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003437776, states[0] = -94.253626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1011250430, states[0] = -94.259170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018969429, states[0] = -94.268534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026768810, states[0] = -94.269924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034355739, states[0] = -93.961653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042001476, states[0] = 37.133131, states[40]= 1.954582
Saving checkpoint... 
Iteration: 1049717632, states[0] = -94.246649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057467424, states[0] = -94.252188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064958844, states[0] = -94.268287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072798992, states[0] = -94.270074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080550666, states[0] = -94.229725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088140186, states[0] = 0.300695, states[40]= 0.000327
Saving checkpoint... 
Iteration: 1095840680, states[0] = -94.243945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103523832, states[0] = -94.250207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111240849, states[0] = -94.258290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118870392, states[0] = -94.269520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126599539, states[0] = -94.246964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134319184, states[0] = -93.819154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141950315, states[0] = -94.241768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149616332, states[0] = -94.247515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157410025, states[0] = -94.252549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165322993, states[0] = -94.255016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173119598, states[0] = -94.261701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180118340, states[0] = 8.746148, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1187644681, states[0] = -94.246455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195236737, states[0] = -94.257421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202947341, states[0] = -94.266951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210609094, states[0] = -94.248542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218312943, states[0] = -93.788384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225864118, states[0] = -94.242017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233470208, states[0] = -94.250007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241247269, states[0] = -94.256521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248900426, states[0] = -94.267491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256572307, states[0] = -94.236546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264267717, states[0] = -76.259585, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1272064510, states[0] = 28.095907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279615162, states[0] = -94.245984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287572293, states[0] = -94.246849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295334531, states[0] = -94.253106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1302997315, states[0] = -94.264290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310595710, states[0] = -94.243652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318274978, states[0] = -88.289829, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1325932469, states[0] = -94.239810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333715911, states[0] = -94.243280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341407876, states[0] = -94.250407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349302864, states[0] = -94.253439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1356882535, states[0] = -94.266507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364580654, states[0] = -94.238222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372507802, states[0] = -94.201958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380167633, states[0] = -13.693733, states[40]= 0.000825
Saving checkpoint... 
Iteration: 1388180556, states[0] = -19.943703, states[40]= 0.002675
Saving checkpoint... 
Iteration: 1395843552, states[0] = -94.240304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1403844037, states[0] = -94.240201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411435307, states[0] = -94.248809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419488564, states[0] = -94.247306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427296140, states[0] = -94.252720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435058448, states[0] = -94.260692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442694631, states[0] = -94.260278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450339492, states[0] = -93.900268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457976329, states[0] = -94.237635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465876024, states[0] = -94.238962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473774986, states[0] = -94.240522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481601843, states[0] = -94.243860, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489479669, states[0] = -94.246699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497367066, states[0] = -94.249717, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.112796
 - CaMKt in component CaMK (millimolar): 0.002640
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.833949
 - nass in component intracellular_ions (millimolar): 7.834106
 - ki in component intracellular_ions (millimolar): 143.947454
 - kss in component intracellular_ions (millimolar): 143.947438
 - cansr in component intracellular_ions (millimolar): 1.845505
 - cajsr in component intracellular_ions (millimolar): 1.847311
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003918
 - hf in component INa (dimensionless): 0.865620
 - hs in component INa (dimensionless): 0.865620
 - j in component INa (dimensionless): 0.865623
 - hsp in component INa (dimensionless): 0.699318
 - jp in component INa (dimensionless): 0.865625
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707897
 - hLp in component INaL (dimensionless): 0.513427
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.990062
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.995926
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994708
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004588
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009150
 - xs1 in component IKs (dimensionless): 0.054564
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997537
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
08:03:56 (136854): called boinc_finish(0)

</stderr_txt>
]]>


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