𝕏

Task 56124461

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_634_0
Workunit 26653847
Created 4 Jul 2024, 20:56:16 UTC
Sent 5 Jul 2024, 1:21:54 UTC
Report deadline 8 Jul 2024, 10:57:54 UTC
Received 6 Jul 2024, 15:28:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 49 min 1 sec
CPU time 1 hours 59 min 55 sec
Validate state Valid
Credit 66.05
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.40 MB
Peak swap size 5.43 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_634.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_634_0_r657577782_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pueyo_APDR-conf_634_0_r657577782_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.278792
     * GNaL_b in INaL: 0.005761
     * Gto_b in Ito: 0.083861
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031924
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.164186
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.438437
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033803
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10933796, states[0] = -95.112631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24361048, states[0] = -95.054970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36593360, states[0] = -15.458369, states[40]= 0.001415
Saving checkpoint... 
Iteration: 49433789, states[0] = -95.046282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62961323, states[0] = -95.043184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76185305, states[0] = -94.811456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87883455, states[0] = -95.015767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100350013, states[0] = -94.999952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114703649, states[0] = -94.843336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128320591, states[0] = -94.980969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141289702, states[0] = -94.957640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153713838, states[0] = -94.860066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163946425, states[0] = -95.025084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177942677, states[0] = -95.024075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193011421, states[0] = 22.805816, states[40]= 0.038026
Saving checkpoint... 
Iteration: 207195840, states[0] = -94.824230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219898052, states[0] = -95.012790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233366580, states[0] = -95.001824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246744759, states[0] = -94.907548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260592630, states[0] = -12.855296, states[40]= 0.001797
Saving checkpoint... 
Iteration: 274950105, states[0] = -95.024914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290094377, states[0] = -14.467998, states[40]= 0.001542
Saving checkpoint... 
Iteration: 303780820, states[0] = -94.948038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318055726, states[0] = 9.263884, states[40]= 0.004905
Saving checkpoint... 
Iteration: 330946127, states[0] = -95.024109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344182866, states[0] = -94.792100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356858302, states[0] = -94.998191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371605314, states[0] = -24.814578, states[40]= 0.000712
Saving checkpoint... 
Iteration: 385672684, states[0] = -94.656257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398491795, states[0] = -95.031133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410608298, states[0] = -27.646743, states[40]= 0.000578
Saving checkpoint... 
Iteration: 424484198, states[0] = -95.030140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438506129, states[0] = 26.158133, states[40]= 0.124500
Saving checkpoint... 
Iteration: 450076711, states[0] = -0.772311, states[40]= 0.004144
Saving checkpoint... 
Iteration: 463560105, states[0] = 7.430938, states[40]= 0.004840
Saving checkpoint... 
Iteration: 478237132, states[0] = -94.896658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492793292, states[0] = -94.958804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504624311, states[0] = -43.281458, states[40]= 0.000079
Saving checkpoint... 
Iteration: 519496707, states[0] = -95.031649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532830281, states[0] = -94.984138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547381139, states[0] = -95.006965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561294920, states[0] = -94.960085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573991882, states[0] = -95.031031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585279464, states[0] = -94.946575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598644190, states[0] = -65.452916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 613290334, states[0] = -94.956266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625944386, states[0] = -95.023582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638338067, states[0] = -94.988330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652640539, states[0] = -61.011499, states[40]= 0.000004
Saving checkpoint... 
Iteration: 667485142, states[0] = -95.030111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682472933, states[0] = -95.028394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695263003, states[0] = -94.929590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709633562, states[0] = -53.135028, states[40]= 0.000017
Saving checkpoint... 
Iteration: 722222000, states[0] = -94.872807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736460151, states[0] = -95.026348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750517697, states[0] = 21.680226, states[40]= 0.012418
Saving checkpoint... 
Iteration: 765121304, states[0] = -40.232209, states[40]= 0.000125
Saving checkpoint... 
Iteration: 779647551, states[0] = -69.929734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793867421, states[0] = -95.001696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806113812, states[0] = -32.911120, states[40]= 0.000336
Saving checkpoint... 
Iteration: 818407077, states[0] = -95.014830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829690252, states[0] = -94.811644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843768893, states[0] = -94.935878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856681798, states[0] = -94.787593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868525813, states[0] = 19.866128, states[40]= 0.006898
Saving checkpoint... 
Iteration: 881826654, states[0] = -94.981819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894757975, states[0] = -94.923700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901660920, states[0] = -90.729787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916185102, states[0] = -94.798867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927916944, states[0] = -95.017342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939631650, states[0] = -51.048389, states[40]= 0.000023
Saving checkpoint... 
Iteration: 953990386, states[0] = -95.030604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967237804, states[0] = -94.897319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982698571, states[0] = -94.829096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996665088, states[0] = -93.503502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010338222, states[0] = -94.988175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024207290, states[0] = -94.846217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038360410, states[0] = -94.998660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052729170, states[0] = -94.884255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065963491, states[0] = -95.026689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078568977, states[0] = 3.377621, states[40]= 0.004607
Saving checkpoint... 
Iteration: 1093081935, states[0] = -4.122088, states[40]= 0.003570
Saving checkpoint... 
Iteration: 1107690715, states[0] = -94.812496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121319769, states[0] = -94.977475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134015390, states[0] = 22.080777, states[40]= 0.017354
Saving checkpoint... 
Iteration: 1148608266, states[0] = -27.615868, states[40]= 0.000580
Saving checkpoint... 
Iteration: 1161977731, states[0] = -95.028785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175480209, states[0] = -95.029123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189107828, states[0] = -27.199634, states[40]= 0.000599
Saving checkpoint... 
Iteration: 1203056700, states[0] = 8.863667, states[40]= 0.004892
Saving checkpoint... 
Iteration: 1215640482, states[0] = -60.944014, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1229905568, states[0] = -95.014153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243221901, states[0] = -94.872307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256855972, states[0] = -94.996596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271301880, states[0] = -94.965055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284942898, states[0] = -95.022874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298458281, states[0] = -95.025677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312205237, states[0] = -94.842091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325950155, states[0] = -95.024225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337877975, states[0] = -95.005343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352192284, states[0] = -94.815764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366881990, states[0] = -95.006741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378760723, states[0] = -94.926578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392280921, states[0] = -94.947425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404481989, states[0] = -95.029222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416101940, states[0] = -21.615260, states[40]= 0.000868
Saving checkpoint... 
Iteration: 1427016050, states[0] = 21.969419, states[40]= 0.015617
Saving checkpoint... 
Iteration: 1438004747, states[0] = 29.179585, states[40]= 0.150587
Saving checkpoint... 
Iteration: 1451372043, states[0] = -95.003076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465454419, states[0] = -95.024903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478813515, states[0] = -94.973186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492217780, states[0] = -94.865081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503981913, states[0] = -15.125767, states[40]= 0.001581
Saving checkpoint... 
Iteration: 1517667836, states[0] = -95.245381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531797785, states[0] = -95.281540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544527379, states[0] = -71.841963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1554291972, states[0] = -95.291172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565898971, states[0] = -95.185708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579942666, states[0] = -93.986209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593623817, states[0] = 19.570843, states[40]= 0.008700
Saving checkpoint... 
Iteration: 1606323151, states[0] = -66.826835, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1618172371, states[0] = -95.287733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633252207, states[0] = 6.180847, states[40]= 0.005477
Saving checkpoint... 
Iteration: 1647152420, states[0] = -95.042399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660303831, states[0] = -42.695329, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1672654626, states[0] = -95.070143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687526926, states[0] = 18.363968, states[40]= 0.007705
Saving checkpoint... 
Iteration: 1701988825, states[0] = -26.061173, states[40]= 0.000651
Saving checkpoint... 
Iteration: 1715755985, states[0] = 3.972671, states[40]= 0.005282
Saving checkpoint... 
Iteration: 1730187848, states[0] = -24.994272, states[40]= 0.000709
Saving checkpoint... 
Iteration: 1743275566, states[0] = -95.291879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758015967, states[0] = 22.031129, states[40]= 0.017409
Saving checkpoint... 
Iteration: 1772830211, states[0] = -78.560202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786416307, states[0] = -95.224384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802054622, states[0] = 8.483930, states[40]= 0.004998
Saving checkpoint... 
Iteration: 1816243283, states[0] = -94.945555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829745784, states[0] = -94.936888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842336951, states[0] = -95.006957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855238943, states[0] = -94.912252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866776224, states[0] = -94.952401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880338796, states[0] = -94.994371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894702564, states[0] = -94.840778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908743662, states[0] = -94.907736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921199080, states[0] = -94.831453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934414596, states[0] = -95.017371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948943381, states[0] = -95.023351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962750882, states[0] = -94.914897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977091244, states[0] = -11.615402, states[40]= 0.002019
Saving checkpoint... 
Iteration: 1991592875, states[0] = -13.089483, states[40]= 0.001757
Saving checkpoint... 
Iteration: 2005685092, states[0] = -94.798255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020649090, states[0] = -72.166105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2034435442, states[0] = -95.020899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049755358, states[0] = -94.919835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067683820, states[0] = -94.794216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085920974, states[0] = -95.017555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096647711, states[0] = -70.154553, states[40]= 0.000001
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.906861
 - CaMKt in component CaMK (millimolar): 0.006956
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.577216
 - nass in component intracellular_ions (millimolar): 6.577276
 - ki in component intracellular_ions (millimolar): 145.400610
 - kss in component intracellular_ions (millimolar): 145.400591
 - cansr in component intracellular_ions (millimolar): 1.310921
 - cajsr in component intracellular_ions (millimolar): 1.273002
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003617
 - hf in component INa (dimensionless): 0.880088
 - hs in component INa (dimensionless): 0.880083
 - j in component INa (dimensionless): 0.880055
 - hsp in component INa (dimensionless): 0.725994
 - jp in component INa (dimensionless): 0.880035
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710173
 - hLp in component INaL (dimensionless): 0.452520
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621745
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696715
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935557
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001599
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330462
 - xs1 in component IKs (dimensionless): 0.240799
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:28:05 (8248): called boinc_finish(0)

</stderr_txt>
]]>


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