𝕏

Task 56122783

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_133_0
Workunit 26653011
Created 4 Jul 2024, 20:55:29 UTC
Sent 5 Jul 2024, 1:09:10 UTC
Report deadline 8 Jul 2024, 4:01:58 UTC
Received 5 Jul 2024, 11:34:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233544
Run time 2 hours 3 min 51 sec
CPU time 2 hours 3 min 2 sec
Validate state Valid
Credit 50.15
Device peak FLOPS 3.72 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.18 MB
Peak swap size 6.19 MB
Peak disk usage 0.05 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_133.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_133_0_r774794084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_133_0_r774794084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 104.129814
     * GNaL_b in INaL: 0.005767
     * Gto_b in Ito: 0.084373
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009587
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.164202
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.361968
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033858
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14442507, states[0] = -94.874185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29106162, states[0] = 3.379172, states[40]= 0.005146
Saving checkpoint... 
Iteration: 43574229, states[0] = 15.278200, states[40]= 0.004788
Saving checkpoint... 
Iteration: 58210910, states[0] = -34.686080, states[40]= 0.002122
Saving checkpoint... 
Iteration: 73198021, states[0] = -29.739766, states[40]= 0.003576
Saving checkpoint... 
Iteration: 88105209, states[0] = 5.066582, states[40]= 0.005166
Saving checkpoint... 
Iteration: 102844880, states[0] = -94.665205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117724265, states[0] = -37.686613, states[40]= 0.001419
Saving checkpoint... 
Iteration: 132930064, states[0] = -94.746541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147473211, states[0] = -94.767402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162037642, states[0] = 26.934331, states[40]= 0.003031
Saving checkpoint... 
Iteration: 177305362, states[0] = -91.465776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192512207, states[0] = 30.845630, states[40]= 0.023553
Saving checkpoint... 
Iteration: 208069515, states[0] = 17.557484, states[40]= 0.004664
Saving checkpoint... 
Iteration: 223416748, states[0] = -94.732642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238391558, states[0] = -94.711259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252898260, states[0] = -94.717283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267993660, states[0] = -94.771466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282708977, states[0] = -31.914656, states[40]= 0.002822
Saving checkpoint... 
Iteration: 296642652, states[0] = -9.617747, states[40]= 0.002915
Saving checkpoint... 
Iteration: 311188221, states[0] = -25.607223, states[40]= 0.004734
Saving checkpoint... 
Iteration: 326183417, states[0] = -24.216338, states[40]= 0.004990
Saving checkpoint... 
Iteration: 340610764, states[0] = 3.425897, states[40]= 0.005047
Saving checkpoint... 
Iteration: 355553544, states[0] = 22.392676, states[40]= 0.003870
Saving checkpoint... 
Iteration: 369743653, states[0] = -44.569672, states[40]= 0.000536
Saving checkpoint... 
Iteration: 384688143, states[0] = -25.581581, states[40]= 0.004740
Saving checkpoint... 
Iteration: 399621970, states[0] = -0.848842, states[40]= 0.004608
Saving checkpoint... 
Iteration: 413955872, states[0] = -94.755368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428929611, states[0] = -94.740444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444192977, states[0] = -26.991020, states[40]= 0.004379
Saving checkpoint... 
Iteration: 459168162, states[0] = -19.641701, states[40]= 0.004594
Saving checkpoint... 
Iteration: 474111193, states[0] = 3.268098, states[40]= 0.005037
Saving checkpoint... 
Iteration: 488834397, states[0] = -94.635602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504101519, states[0] = 6.784089, states[40]= 0.005174
Saving checkpoint... 
Iteration: 519056212, states[0] = 21.608539, states[40]= 0.004021
Saving checkpoint... 
Iteration: 533404018, states[0] = -94.721296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548084235, states[0] = 12.780334, states[40]= 0.005071
Saving checkpoint... 
Iteration: 563125307, states[0] = -2.183392, states[40]= 0.004394
Saving checkpoint... 
Iteration: 578191466, states[0] = -26.547706, states[40]= 0.004502
Saving checkpoint... 
Iteration: 593268222, states[0] = -55.781515, states[40]= 0.000086
Saving checkpoint... 
Iteration: 608128219, states[0] = -3.375934, states[40]= 0.004175
Saving checkpoint... 
Iteration: 622621347, states[0] = -0.602608, states[40]= 0.004643
Saving checkpoint... 
Iteration: 637821194, states[0] = -94.575698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652870379, states[0] = -94.687238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667744704, states[0] = -45.002355, states[40]= 0.000502
Saving checkpoint... 
Iteration: 682570113, states[0] = 17.384129, states[40]= 0.004688
Saving checkpoint... 
Iteration: 697633368, states[0] = -5.547690, states[40]= 0.003727
Saving checkpoint... 
Iteration: 712792476, states[0] = -73.806080, states[40]= 0.000004
Saving checkpoint... 
Iteration: 728153246, states[0] = -14.190598, states[40]= 0.002704
Saving checkpoint... 
Iteration: 743091368, states[0] = 10.348611, states[40]= 0.005160
Saving checkpoint... 
Iteration: 757683391, states[0] = -24.205943, states[40]= 0.004991
Saving checkpoint... 
Iteration: 772446405, states[0] = -94.749584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786918859, states[0] = -94.732240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801407542, states[0] = -94.723556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816708386, states[0] = -31.714347, states[40]= 0.002883
Saving checkpoint... 
Iteration: 832295754, states[0] = -78.061038, states[40]= 0.000002
Saving checkpoint... 
Iteration: 847164920, states[0] = -18.576821, states[40]= 0.004145
Saving checkpoint... 
Iteration: 862397075, states[0] = -94.714461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877008677, states[0] = 30.731432, states[40]= 0.070167
Saving checkpoint... 
Iteration: 892308346, states[0] = -92.960162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907126230, states[0] = -2.558119, states[40]= 0.004328
Saving checkpoint... 
Iteration: 921872956, states[0] = -94.689611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935871325, states[0] = -94.687674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950946985, states[0] = -94.749470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965681481, states[0] = -23.652348, states[40]= 0.005058
Saving checkpoint... 
Iteration: 980576751, states[0] = 15.259630, states[40]= 0.004905
Saving checkpoint... 
Iteration: 995560518, states[0] = 20.328409, states[40]= 0.004254
Saving checkpoint... 
Iteration: 1010616696, states[0] = 1.199683, states[40]= 0.004863
Saving checkpoint... 
Iteration: 1025795030, states[0] = -77.057873, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1040941541, states[0] = -94.746223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055838456, states[0] = -94.641407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070553895, states[0] = 22.290624, states[40]= 0.003890
Saving checkpoint... 
Iteration: 1084757103, states[0] = -50.395750, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1099918724, states[0] = -94.731390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114952592, states[0] = -94.752027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128922255, states[0] = -94.733823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144133326, states[0] = -5.529043, states[40]= 0.003731
Saving checkpoint... 
Iteration: 1158580989, states[0] = 13.865848, states[40]= 0.005009
Saving checkpoint... 
Iteration: 1173339731, states[0] = -94.643243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188749077, states[0] = -46.846991, states[40]= 0.000378
Saving checkpoint... 
Iteration: 1203592705, states[0] = 9.886321, states[40]= 0.005169
Saving checkpoint... 
Iteration: 1217517416, states[0] = 30.969501, states[40]= 0.006303
Saving checkpoint... 
Iteration: 1232191613, states[0] = -26.589886, states[40]= 0.004490
Saving checkpoint... 
Iteration: 1246990891, states[0] = -94.767971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262032330, states[0] = 28.390368, states[40]= 0.002886
Saving checkpoint... 
Iteration: 1276542825, states[0] = 25.503578, states[40]= 0.003282
Saving checkpoint... 
Iteration: 1291088133, states[0] = 11.459799, states[40]= 0.005128
Saving checkpoint... 
Iteration: 1306040667, states[0] = 26.119363, states[40]= 0.003180
Saving checkpoint... 
Iteration: 1321035907, states[0] = 27.445779, states[40]= 0.002988
Saving checkpoint... 
Iteration: 1335733171, states[0] = -40.403096, states[40]= 0.000975
Saving checkpoint... 
Iteration: 1350777303, states[0] = -60.930081, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1365621763, states[0] = -0.765637, states[40]= 0.004620
Saving checkpoint... 
Iteration: 1380695745, states[0] = -27.808458, states[40]= 0.004136
Saving checkpoint... 
Iteration: 1395437215, states[0] = -94.742841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410411421, states[0] = -94.725169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424496294, states[0] = -94.769375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439684898, states[0] = -24.640880, states[40]= 0.004924
Saving checkpoint... 
Iteration: 1454986744, states[0] = -94.765998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470467540, states[0] = -94.758274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485018728, states[0] = 30.892786, states[40]= 0.005003
Saving checkpoint... 
Iteration: 1500134490, states[0] = -18.954030, states[40]= 0.002156
Saving checkpoint... 
Iteration: 1515056742, states[0] = 17.548571, states[40]= 0.006308
Saving checkpoint... 
Iteration: 1529998865, states[0] = -44.884946, states[40]= 0.000747
Saving checkpoint... 
Iteration: 1544654396, states[0] = -9.495847, states[40]= 0.002924
Saving checkpoint... 
Iteration: 1559500189, states[0] = -94.517763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574335305, states[0] = -57.877208, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1589290706, states[0] = -33.136309, states[40]= 0.002691
Saving checkpoint... 
Iteration: 1604119914, states[0] = 6.983305, states[40]= 0.004570
Saving checkpoint... 
Iteration: 1618619146, states[0] = -94.433969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633876947, states[0] = -94.423689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648100455, states[0] = -94.373447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662378800, states[0] = -94.408748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676951110, states[0] = -94.411683, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.282839
 - CaMKt in component CaMK (millimolar): 0.001259
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.166318
 - nass in component intracellular_ions (millimolar): 6.166392
 - ki in component intracellular_ions (millimolar): 145.760287
 - kss in component intracellular_ions (millimolar): 145.760281
 - cansr in component intracellular_ions (millimolar): 1.482900
 - cajsr in component intracellular_ions (millimolar): 1.482384
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003852
 - hf in component INa (dimensionless): 0.868837
 - hs in component INa (dimensionless): 0.868837
 - j in component INa (dimensionless): 0.868838
 - hsp in component INa (dimensionless): 0.705159
 - jp in component INa (dimensionless): 0.868839
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712549
 - hLp in component INaL (dimensionless): 0.519553
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.995926
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.998528
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997562
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002466
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003521
 - xs1 in component IKs (dimensionless): 0.036438
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997495
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:49:06 (2716): called boinc_finish(0)

</stderr_txt>
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