𝕏

Task 56116086

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_926_0
Workunit 26649670
Created 4 Jul 2024, 20:52:01 UTC
Sent 5 Jul 2024, 0:30:06 UTC
Report deadline 8 Jul 2024, 0:30:06 UTC
Received 6 Jul 2024, 4:39:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 54573
Run time 2 hours 15 min 44 sec
CPU time 2 hours 9 min 54 sec
Validate state Valid
Credit 47.88
Device peak FLOPS 3.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.64 MB
Peak swap size 4.10 GB
Peak disk usage 0.15 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_926.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_926_0_r461935329_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_400-conf_926_0_r461935329_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.991391
     * GNaL_b in INaL: 0.005818
     * Gto_b in Ito: 0.085218
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031847
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163053
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.322678
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032573
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6755267, states[0] = -84.734050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17701150, states[0] = -36.490869, states[40]= 0.000332
Saving checkpoint... 
Iteration: 28668062, states[0] = 2.868478, states[40]= 0.000244
Saving checkpoint... 
Iteration: 39920450, states[0] = -62.073145, states[40]= 0.000018
Saving checkpoint... 
Iteration: 51289037, states[0] = -22.891196, states[40]= 0.000227
Saving checkpoint... 
Iteration: 62312948, states[0] = -53.491117, states[40]= 0.000043
Saving checkpoint... 
Iteration: 72310607, states[0] = -50.842353, states[40]= 0.000055
Saving checkpoint... 
Iteration: 83050644, states[0] = 14.643994, states[40]= 0.000014
Saving checkpoint... 
Iteration: 93939451, states[0] = -83.680500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104573223, states[0] = -84.790459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115735155, states[0] = -82.253495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123299661, states[0] = -37.747800, states[40]= 0.000152
Saving checkpoint... 
Iteration: 133879180, states[0] = -10.793274, states[40]= 0.000233
Saving checkpoint... 
Iteration: 144896768, states[0] = -34.155863, states[40]= 0.000180
Saving checkpoint... 
Iteration: 156146098, states[0] = -84.378034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167046540, states[0] = 17.077992, states[40]= 0.000007
Saving checkpoint... 
Iteration: 178186716, states[0] = -84.906473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189196839, states[0] = -84.976515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200202607, states[0] = 34.421276, states[40]= 0.963615
Saving checkpoint... 
Iteration: 211467375, states[0] = 2.231108, states[40]= 0.000132
Saving checkpoint... 
Iteration: 222193723, states[0] = -84.954582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233005054, states[0] = 29.353457, states[40]= 0.412869
Saving checkpoint... 
Iteration: 244254916, states[0] = 11.733346, states[40]= 0.000026
Saving checkpoint... 
Iteration: 255379912, states[0] = -84.848552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266596988, states[0] = -84.973787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277560584, states[0] = -84.655197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288570739, states[0] = -84.763400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299364698, states[0] = -84.700622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310486859, states[0] = -21.291881, states[40]= 0.000182
Saving checkpoint... 
Iteration: 321169062, states[0] = -84.745072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332223534, states[0] = 28.797465, states[40]= 0.000477
Saving checkpoint... 
Iteration: 343056228, states[0] = 10.839908, states[40]= 0.000032
Saving checkpoint... 
Iteration: 353741238, states[0] = -84.003553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364842734, states[0] = 19.322029, states[40]= 0.000004
Saving checkpoint... 
Iteration: 375697825, states[0] = -35.525252, states[40]= 0.000169
Saving checkpoint... 
Iteration: 386655182, states[0] = 11.556349, states[40]= 0.000027
Saving checkpoint... 
Iteration: 397636782, states[0] = 22.632658, states[40]= 0.000005
Saving checkpoint... 
Iteration: 408777555, states[0] = -84.820371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420074429, states[0] = -4.876775, states[40]= 0.000227
Saving checkpoint... 
Iteration: 431129324, states[0] = -77.172242, states[40]= 0.000002
Saving checkpoint... 
Iteration: 441936382, states[0] = -82.848526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452709432, states[0] = -50.047821, states[40]= 0.000055
Saving checkpoint... 
Iteration: 463806856, states[0] = 28.941007, states[40]= 0.216973
Saving checkpoint... 
Iteration: 474766786, states[0] = -84.713745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485905524, states[0] = -45.152727, states[40]= 0.000087
Saving checkpoint... 
Iteration: 496716821, states[0] = -59.565261, states[40]= 0.000020
Saving checkpoint... 
Iteration: 507904656, states[0] = -44.068063, states[40]= 0.000095
Saving checkpoint... 
Iteration: 518860386, states[0] = 7.871641, states[40]= 0.000056
Saving checkpoint... 
Iteration: 529753023, states[0] = -84.538508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540606278, states[0] = 28.909773, states[40]= 0.267101
Saving checkpoint... 
Iteration: 551634281, states[0] = 23.949828, states[40]= 0.000011
Saving checkpoint... 
Iteration: 562605796, states[0] = 28.979366, states[40]= 0.317282
Saving checkpoint... 
Iteration: 573705638, states[0] = -45.288104, states[40]= 0.000086
Saving checkpoint... 
Iteration: 584869213, states[0] = 0.567901, states[40]= 0.000158
Saving checkpoint... 
Iteration: 595862477, states[0] = 6.286885, states[40]= 0.000074
Saving checkpoint... 
Iteration: 606208727, states[0] = 29.439277, states[40]= 0.109594
Saving checkpoint... 
Iteration: 617346033, states[0] = -84.350963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628265998, states[0] = 3.435637, states[40]= 0.000113
Saving checkpoint... 
Iteration: 639119598, states[0] = -63.338356, states[40]= 0.000013
Saving checkpoint... 
Iteration: 645980768, states[0] = -84.835595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657100019, states[0] = -38.264647, states[40]= 0.000146
Saving checkpoint... 
Iteration: 668171805, states[0] = -84.754071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679472161, states[0] = -2.359488, states[40]= 0.000201
Saving checkpoint... 
Iteration: 690692449, states[0] = -28.633524, states[40]= 0.000196
Saving checkpoint... 
Iteration: 701844544, states[0] = 18.274341, states[40]= 0.000005
Saving checkpoint... 
Iteration: 712793503, states[0] = -84.928009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724003143, states[0] = 32.852752, states[40]= 0.802229
Saving checkpoint... 
Iteration: 735167425, states[0] = -84.706856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745722637, states[0] = -67.659740, states[40]= 0.000007
Saving checkpoint... 
Iteration: 756728898, states[0] = -76.585122, states[40]= 0.000002
Saving checkpoint... 
Iteration: 767672237, states[0] = -2.435611, states[40]= 0.000202
Saving checkpoint... 
Iteration: 778666656, states[0] = 2.877491, states[40]= 0.000121
Saving checkpoint... 
Iteration: 789781052, states[0] = -84.830534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800494518, states[0] = -31.290428, states[40]= 0.000192
Saving checkpoint... 
Iteration: 811548253, states[0] = -84.419458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822790058, states[0] = -84.898362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 833967408, states[0] = -84.701544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845067297, states[0] = 2.320477, states[40]= 0.000130
Saving checkpoint... 
Iteration: 855825712, states[0] = 27.970471, states[40]= 0.000218
Saving checkpoint... 
Iteration: 866880332, states[0] = -12.358490, states[40]= 0.000221
Saving checkpoint... 
Iteration: 877924449, states[0] = -70.295639, states[40]= 0.000005
Saving checkpoint... 
Iteration: 888960488, states[0] = -84.622120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900045712, states[0] = 17.585750, states[40]= 0.000006
Saving checkpoint... 
Iteration: 911030581, states[0] = 25.799786, states[40]= 0.000038
Saving checkpoint... 
Iteration: 922096880, states[0] = -34.290755, states[40]= 0.000177
Saving checkpoint... 
Iteration: 932687026, states[0] = -21.473012, states[40]= 0.000182
Saving checkpoint... 
Iteration: 944007943, states[0] = 29.194415, states[40]= 0.146044
Saving checkpoint... 
Iteration: 954604419, states[0] = 30.039068, states[40]= 0.515350
Saving checkpoint... 
Iteration: 965773370, states[0] = -84.753535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976813755, states[0] = 30.573180, states[40]= 0.016988
Saving checkpoint... 
Iteration: 987887489, states[0] = -22.089621, states[40]= 0.000182
Saving checkpoint... 
Iteration: 999012835, states[0] = 30.481345, states[40]= 0.023891
Saving checkpoint... 
Iteration: 1010338976, states[0] = -83.577644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021655723, states[0] = 11.203499, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1032971477, states[0] = -84.731983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044103366, states[0] = -42.418256, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1055189961, states[0] = -84.885718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065352540, states[0] = -84.501781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076251096, states[0] = 14.262687, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1087453143, states[0] = 12.934972, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1098493624, states[0] = -30.121553, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1109573884, states[0] = -84.750896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1120456082, states[0] = 10.959787, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1131090199, states[0] = -25.669800, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1142382477, states[0] = -84.824037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1153628585, states[0] = 26.736414, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1164482607, states[0] = -15.445247, states[40]= 0.000200
Saving checkpoint... 
Iteration: 1174971412, states[0] = -84.723986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185486542, states[0] = -20.804551, states[40]= 0.000181
Saving checkpoint... 
Iteration: 1196614738, states[0] = 30.613970, states[40]= 0.011806
Saving checkpoint... 
Iteration: 1207879799, states[0] = -11.616287, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1219141432, states[0] = -83.969995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230427107, states[0] = 27.392639, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1241470774, states[0] = -0.914797, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1252705264, states[0] = -44.768363, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1263161395, states[0] = -84.613256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273388726, states[0] = -84.865532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283193467, states[0] = -84.898480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294334322, states[0] = -81.726048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305331041, states[0] = -79.005096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316401996, states[0] = 35.867666, states[40]= 1.160699
Saving checkpoint... 
Iteration: 1326973762, states[0] = -84.738494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337972820, states[0] = -84.729049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349069333, states[0] = 0.484852, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1359784770, states[0] = -84.831106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370631214, states[0] = 25.503682, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1377213999, states[0] = 30.594397, states[40]= 0.015512
Saving checkpoint... 
Iteration: 1388537634, states[0] = -83.199085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399334927, states[0] = -82.067733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410539679, states[0] = -83.689952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421784673, states[0] = -84.827151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432815196, states[0] = 30.614572, states[40]= 0.009967
Saving checkpoint... 
Iteration: 1444158090, states[0] = -84.563465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454823330, states[0] = 28.892172, states[40]= 0.000513
Saving checkpoint... 
Iteration: 1465893204, states[0] = -29.554591, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1476871570, states[0] = -1.709048, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1487676574, states[0] = -7.398224, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1498649001, states[0] = 15.593977, states[40]= 0.000010
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.805088
 - CaMKt in component CaMK (millimolar): 0.148638
 - cass in component intracellular_ions (millimolar): 0.000143
 - nai in component intracellular_ions (millimolar): 7.154116
 - nass in component intracellular_ions (millimolar): 7.154384
 - ki in component intracellular_ions (millimolar): 144.117207
 - kss in component intracellular_ions (millimolar): 144.117173
 - cansr in component intracellular_ions (millimolar): 2.943071
 - cajsr in component intracellular_ions (millimolar): 1.956371
 - cai in component intracellular_ions (millimolar): 0.000137
 - m in component INa (dimensionless): 0.009999
 - hf in component INa (dimensionless): 0.582586
 - hs in component INa (dimensionless): 0.581926
 - j in component INa (dimensionless): 0.574100
 - hsp in component INa (dimensionless): 0.332986
 - jp in component INa (dimensionless): 0.557214
 - mL in component INaL (dimensionless): 0.000337
 - hL in component INaL (dimensionless): 0.236582
 - hLp in component INaL (dimensionless): 0.097261
 - a in component Ito (dimensionless): 0.001232
 - iF in component Ito (dimensionless): 0.999234
 - iS in component Ito (dimensionless): 0.180377
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999234
 - iSp in component Ito (dimensionless): 0.200892
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.725323
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.957474
 - jca in component ICaL (dimensionless): 0.956817
 - ffp in component ICaL (dimensionless): 0.999936
 - fcafp in component ICaL (dimensionless): 0.999997
 - nca in component ICaL (dimensionless): 0.020421
 - xrf in component IKr (dimensionless): 0.036265
 - xrs in component IKr (dimensionless): 0.833202
 - xs1 in component IKs (dimensionless): 0.524949
 - xs2 in component IKs (dimensionless): 0.001506
 - xk1 in component IK1 (dimensionless): 0.996735
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
19:38:57 (85426): called boinc_finish(0)

</stderr_txt>
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