𝕏

Task 56116025

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_826_1
Workunit 26649639
Created 4 Jul 2024, 20:52:01 UTC
Sent 5 Jul 2024, 0:30:06 UTC
Report deadline 8 Jul 2024, 0:30:06 UTC
Received 6 Jul 2024, 4:39:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 54573
Run time 2 hours 15 min 49 sec
CPU time 2 hours 9 min 53 sec
Validate state Valid
Credit 42.34
Device peak FLOPS 3.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 4.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_826.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_826_1_r1569574797_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_2000-conf_826_1_r1569574797_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.868537
     * GNaL_b in INaL: 0.005728
     * Gto_b in Ito: 0.085180
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031888
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164659
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.411057
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033319
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7108493, states[0] = -10.568596, states[40]= 0.001386
Saving checkpoint... 
Iteration: 17538840, states[0] = -84.285445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28674553, states[0] = -84.252295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39565769, states[0] = -84.211241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50678510, states[0] = -84.206902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61672286, states[0] = -84.194340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72431682, states[0] = -84.109176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83437299, states[0] = -84.107364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 94342807, states[0] = -83.977607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104911259, states[0] = -84.167121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116150670, states[0] = -44.342329, states[40]= 0.000105
Saving checkpoint... 
Iteration: 126987264, states[0] = -84.158373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138295867, states[0] = -83.844778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149190875, states[0] = -81.846606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160058841, states[0] = 18.684590, states[40]= 0.000085
Saving checkpoint... 
Iteration: 171159706, states[0] = -52.306849, states[40]= 0.000036
Saving checkpoint... 
Iteration: 181927959, states[0] = -84.157048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192884440, states[0] = -84.158861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 203390836, states[0] = -84.042210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214193790, states[0] = -82.533953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225210064, states[0] = -83.399920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236688651, states[0] = -84.161465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247843805, states[0] = -84.159632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258713224, states[0] = -84.161820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269979390, states[0] = -84.152618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281322156, states[0] = -83.916130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292470850, states[0] = -84.111439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303131252, states[0] = -26.586708, states[40]= 0.000475
Saving checkpoint... 
Iteration: 314232396, states[0] = -83.550058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325665086, states[0] = -84.159616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337075828, states[0] = 11.557193, states[40]= 0.000240
Saving checkpoint... 
Iteration: 348014417, states[0] = 30.929348, states[40]= 0.011817
Saving checkpoint... 
Iteration: 359142298, states[0] = -36.453258, states[40]= 0.000267
Saving checkpoint... 
Iteration: 370419699, states[0] = -84.072403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381436710, states[0] = -84.087318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392682760, states[0] = -84.160057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403878377, states[0] = -84.157002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415263005, states[0] = -83.710077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426375942, states[0] = -84.019882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437601017, states[0] = -84.152640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448585098, states[0] = -84.149997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459846168, states[0] = -84.158085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470850319, states[0] = -84.157848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480932813, states[0] = -84.153808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492192457, states[0] = -82.235887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503180750, states[0] = -74.255502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513826500, states[0] = -84.158523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524269684, states[0] = -83.739115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531479600, states[0] = -84.114844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542482443, states[0] = -84.116276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553549490, states[0] = -84.141601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564633177, states[0] = -84.155762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 575762811, states[0] = -84.159801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586851904, states[0] = -84.157098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 598301202, states[0] = -83.855077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609343725, states[0] = -83.962991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619972637, states[0] = -84.150817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630326378, states[0] = -83.924393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641339940, states[0] = -83.954975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651963309, states[0] = -84.151145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663058665, states[0] = 18.781149, states[40]= 0.000084
Saving checkpoint... 
Iteration: 674050178, states[0] = 22.114160, states[40]= 0.000048
Saving checkpoint... 
Iteration: 684537173, states[0] = -84.137363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 695749137, states[0] = -84.159232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707000277, states[0] = -49.878388, states[40]= 0.000003
Saving checkpoint... 
Iteration: 717824469, states[0] = -84.157393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 728669764, states[0] = -84.157474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739517425, states[0] = -84.130473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750578256, states[0] = -84.146951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761574027, states[0] = -84.146053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 772883900, states[0] = -84.154562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783863669, states[0] = -84.155428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795056405, states[0] = 19.686439, states[40]= 0.000072
Saving checkpoint... 
Iteration: 806405975, states[0] = -84.055778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 817181344, states[0] = -74.894597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827745890, states[0] = -84.158473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838586348, states[0] = -84.147917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849619038, states[0] = -84.152580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860794558, states[0] = -84.157481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872062394, states[0] = 17.263676, states[40]= 0.000106
Saving checkpoint... 
Iteration: 883129549, states[0] = -25.051472, states[40]= 0.000473
Saving checkpoint... 
Iteration: 893933427, states[0] = -84.151339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904408726, states[0] = -84.058162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915285512, states[0] = -83.799831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926361619, states[0] = -83.994300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937372349, states[0] = -84.011468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947860577, states[0] = -84.154597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958711329, states[0] = -84.157515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969751387, states[0] = -84.157601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980654836, states[0] = -84.155086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991602469, states[0] = -84.149585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002368856, states[0] = -84.005672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013342777, states[0] = -83.958644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024426309, states[0] = -84.074637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035501726, states[0] = -84.122485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046479680, states[0] = -84.111843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057321541, states[0] = -83.909831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1068550777, states[0] = -84.138899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079855504, states[0] = -84.154038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090997886, states[0] = -84.146622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101951858, states[0] = -84.149118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112997329, states[0] = -84.146523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124271586, states[0] = -83.743581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135087576, states[0] = 6.215074, states[40]= 0.000452
Saving checkpoint... 
Iteration: 1145480390, states[0] = -84.111635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156624455, states[0] = -84.151381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166768453, states[0] = -84.156235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177606184, states[0] = -84.149012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188552807, states[0] = -84.138713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199471941, states[0] = -84.106648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209906349, states[0] = -84.150882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220924308, states[0] = -84.149891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232243247, states[0] = -83.605839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243067691, states[0] = 15.058389, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1253624952, states[0] = -84.150862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260776268, states[0] = -84.155543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271492678, states[0] = -84.117026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282144582, states[0] = -38.483901, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1293199208, states[0] = -83.121493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303946148, states[0] = -84.148237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1315304891, states[0] = -83.862099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326576725, states[0] = -84.143257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337662091, states[0] = -84.153451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348569772, states[0] = -84.141712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359301593, states[0] = -83.851711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369969588, states[0] = -84.146561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377613990, states[0] = -84.148858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388235911, states[0] = -83.563815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399536872, states[0] = -84.133053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410502168, states[0] = -84.120460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421775838, states[0] = -84.154602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433033933, states[0] = 27.770904, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1444192777, states[0] = -82.301927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455009282, states[0] = 29.760794, states[40]= 0.071893
Saving checkpoint... 
Iteration: 1465196878, states[0] = -82.941633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475990172, states[0] = -84.144785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486735239, states[0] = -84.154609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497550856, states[0] = -84.136388, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.020026
 - CaMKt in component CaMK (millimolar): 0.005192
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.336126
 - nass in component intracellular_ions (millimolar): 6.336233
 - ki in component intracellular_ions (millimolar): 145.525973
 - kss in component intracellular_ions (millimolar): 145.525957
 - cansr in component intracellular_ions (millimolar): 1.688895
 - cajsr in component intracellular_ions (millimolar): 1.688218
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.010818
 - hf in component INa (dimensionless): 0.550927
 - hs in component INa (dimensionless): 0.550933
 - j in component INa (dimensionless): 0.550960
 - hsp in component INa (dimensionless): 0.306988
 - jp in component INa (dimensionless): 0.550974
 - mL in component INaL (dimensionless): 0.000392
 - hL in component INaL (dimensionless): 0.386323
 - hLp in component INaL (dimensionless): 0.208475
 - a in component Ito (dimensionless): 0.001298
 - iF in component Ito (dimensionless): 0.999124
 - iS in component Ito (dimensionless): 0.846062
 - ap in component Ito (dimensionless): 0.000662
 - iFp in component Ito (dimensionless): 0.999124
 - iSp in component Ito (dimensionless): 0.875028
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973378
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003207
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.210314
 - xs1 in component IKs (dimensionless): 0.132999
 - xs2 in component IKs (dimensionless): 0.000297
 - xk1 in component IK1 (dimensionless): 0.996914
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
19:51:05 (85520): called boinc_finish(0)

</stderr_txt>
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