𝕏

Task 56110641

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_721_1
Workunit 26646948
Created 4 Jul 2024, 20:49:15 UTC
Sent 5 Jul 2024, 0:04:39 UTC
Report deadline 8 Jul 2024, 0:04:39 UTC
Received 5 Jul 2024, 9:38:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213988
Run time 1 hours 52 min 32 sec
CPU time 1 hours 46 min 21 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.10 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.69 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_721.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_721_1_r235852820_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_721_1_r235852820_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.185919
     * GNaL_b in INaL: 0.005760
     * Gto_b in Ito: 0.084658
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031757
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163754
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.384458
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032359
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8798932, states[0] = 5.330344, states[40]= 0.005487
Saving checkpoint... 
Iteration: 17839622, states[0] = -37.230950, states[40]= 0.000182
Saving checkpoint... 
Iteration: 26748747, states[0] = -87.463442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34686296, states[0] = -87.355068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42207602, states[0] = -87.391767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49252102, states[0] = 38.469187, states[40]= 0.097521
Saving checkpoint... 
Iteration: 57439915, states[0] = -87.349972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65902997, states[0] = -87.249895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75504037, states[0] = 29.874249, states[40]= 0.136576
Saving checkpoint... 
Iteration: 84426582, states[0] = -87.312947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92563198, states[0] = -4.539900, states[40]= 0.004089
Saving checkpoint... 
Iteration: 100265126, states[0] = 22.324975, states[40]= 0.017401
Saving checkpoint... 
Iteration: 107871470, states[0] = -78.974222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115300021, states[0] = 5.620292, states[40]= 0.005618
Saving checkpoint... 
Iteration: 124054726, states[0] = 2.438386, states[40]= 0.005305
Saving checkpoint... 
Iteration: 132582395, states[0] = -26.792808, states[40]= 0.000603
Saving checkpoint... 
Iteration: 141787721, states[0] = 12.872066, states[40]= 0.006224
Saving checkpoint... 
Iteration: 149517900, states[0] = 21.563220, states[40]= 0.012189
Saving checkpoint... 
Iteration: 156602907, states[0] = -51.901159, states[40]= 0.000022
Saving checkpoint... 
Iteration: 164249191, states[0] = -87.433202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172998742, states[0] = -87.432627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181925902, states[0] = -87.307248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191445305, states[0] = -87.351077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199767045, states[0] = 21.817401, states[40]= 0.013417
Saving checkpoint... 
Iteration: 207177827, states[0] = -87.311901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214642428, states[0] = -87.182907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222188645, states[0] = -87.336932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230791419, states[0] = 10.832448, states[40]= 0.006026
Saving checkpoint... 
Iteration: 239592914, states[0] = -39.454333, states[40]= 0.000140
Saving checkpoint... 
Iteration: 247914356, states[0] = -87.276455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255775900, states[0] = 18.638031, states[40]= 0.007575
Saving checkpoint... 
Iteration: 263467771, states[0] = -87.391227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270942259, states[0] = -87.344597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279104486, states[0] = -53.922882, states[40]= 0.000016
Saving checkpoint... 
Iteration: 287800351, states[0] = 5.428557, states[40]= 0.005600
Saving checkpoint... 
Iteration: 296988244, states[0] = -87.419951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306030522, states[0] = 16.550611, states[40]= 0.006821
Saving checkpoint... 
Iteration: 314508790, states[0] = 24.064189, states[40]= 0.060872
Saving checkpoint... 
Iteration: 322054677, states[0] = 2.492492, states[40]= 0.005310
Saving checkpoint... 
Iteration: 329166256, states[0] = -87.281630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337363667, states[0] = -66.656968, states[40]= 0.000002
Saving checkpoint... 
Iteration: 346269448, states[0] = 21.079144, states[40]= 0.010547
Saving checkpoint... 
Iteration: 355430121, states[0] = -87.317241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363074625, states[0] = -17.272995, states[40]= 0.001385
Saving checkpoint... 
Iteration: 370548606, states[0] = 6.543979, states[40]= 0.005691
Saving checkpoint... 
Iteration: 377849931, states[0] = -48.103463, states[40]= 0.000039
Saving checkpoint... 
Iteration: 386214141, states[0] = -87.385253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395236238, states[0] = -87.417316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404585498, states[0] = -30.514927, states[40]= 0.000423
Saving checkpoint... 
Iteration: 412971173, states[0] = -87.396322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421546099, states[0] = 8.091336, states[40]= 0.005810
Saving checkpoint... 
Iteration: 428918149, states[0] = -87.286684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436608674, states[0] = -59.494021, states[40]= 0.000006
Saving checkpoint... 
Iteration: 444250647, states[0] = 36.615887, states[40]= 0.005967
Saving checkpoint... 
Iteration: 452445793, states[0] = -87.351686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461331361, states[0] = -25.504172, states[40]= 0.000674
Saving checkpoint... 
Iteration: 470506639, states[0] = 25.391359, states[40]= 0.096509
Saving checkpoint... 
Iteration: 478270979, states[0] = 20.557717, states[40]= 0.009431
Saving checkpoint... 
Iteration: 485956644, states[0] = -87.372298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493257562, states[0] = 24.690162, states[40]= 0.079723
Saving checkpoint... 
Iteration: 500767688, states[0] = 21.629965, states[40]= 0.012470
Saving checkpoint... 
Iteration: 509014482, states[0] = 22.502803, states[40]= 0.019280
Saving checkpoint... 
Iteration: 517493884, states[0] = -87.426538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526911715, states[0] = -87.268650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535669433, states[0] = -87.290020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543829445, states[0] = -23.169884, states[40]= 0.000819
Saving checkpoint... 
Iteration: 551426048, states[0] = -87.307079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559203119, states[0] = -87.365790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567198598, states[0] = -87.357149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575651863, states[0] = -87.237832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583973607, states[0] = -87.399786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592996268, states[0] = -87.429213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600879798, states[0] = -86.028141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608560873, states[0] = -2.352461, states[40]= 0.004557
Saving checkpoint... 
Iteration: 615912824, states[0] = -87.271733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624171362, states[0] = -87.295024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633041825, states[0] = 10.602095, states[40]= 0.006006
Saving checkpoint... 
Iteration: 642309939, states[0] = -1.556949, states[40]= 0.004708
Saving checkpoint... 
Iteration: 650634035, states[0] = -86.848836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658624362, states[0] = -82.504988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665597893, states[0] = -45.555348, states[40]= 0.000058
Saving checkpoint... 
Iteration: 673576612, states[0] = -19.704693, states[40]= 0.001103
Saving checkpoint... 
Iteration: 682370867, states[0] = -77.974720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691207073, states[0] = -87.372853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700362568, states[0] = -65.015053, states[40]= 0.000003
Saving checkpoint... 
Iteration: 708581189, states[0] = -25.294642, states[40]= 0.000686
Saving checkpoint... 
Iteration: 716681346, states[0] = -87.319784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724969689, states[0] = -87.393735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733255216, states[0] = 27.194692, states[40]= 0.123140
Saving checkpoint... 
Iteration: 742149917, states[0] = -87.230367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749855981, states[0] = -55.879062, states[40]= 0.000012
Saving checkpoint... 
Iteration: 758427823, states[0] = -87.311258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768228358, states[0] = -87.406414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776441530, states[0] = -87.342533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784064723, states[0] = -5.945746, states[40]= 0.003756
Saving checkpoint... 
Iteration: 791813819, states[0] = -5.053766, states[40]= 0.003969
Saving checkpoint... 
Iteration: 799134074, states[0] = -86.852593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807414852, states[0] = -87.277249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816209510, states[0] = -87.377003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824533181, states[0] = 15.247687, states[40]= 0.006551
Saving checkpoint... 
Iteration: 832789124, states[0] = 12.114863, states[40]= 0.006144
Saving checkpoint... 
Iteration: 840445899, states[0] = -87.351503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847889806, states[0] = -87.141205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856451324, states[0] = -87.362111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864939631, states[0] = -87.338378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873201036, states[0] = -87.361546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881690512, states[0] = -87.340257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889533064, states[0] = 15.306463, states[40]= 0.006561
Saving checkpoint... 
Iteration: 896986037, states[0] = -87.416548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904386169, states[0] = -87.011994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912317506, states[0] = -8.877803, states[40]= 0.003033
Saving checkpoint... 
Iteration: 920330925, states[0] = -24.973136, states[40]= 0.000705
Saving checkpoint... 
Iteration: 929080706, states[0] = -24.706540, states[40]= 0.000721
Saving checkpoint... 
Iteration: 937461511, states[0] = -87.380305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945565612, states[0] = -6.852263, states[40]= 0.003534
Saving checkpoint... 
Iteration: 952802923, states[0] = 3.716761, states[40]= 0.005442
Saving checkpoint... 
Iteration: 960323097, states[0] = -15.410844, states[40]= 0.001660
Saving checkpoint... 
Iteration: 967942448, states[0] = -87.344272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976165023, states[0] = -87.277552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984596385, states[0] = -43.689608, states[40]= 0.000076
Saving checkpoint... 
Iteration: 993704186, states[0] = -87.367320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002187507, states[0] = -87.333589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009330009, states[0] = -23.857225, states[40]= 0.000773
Saving checkpoint... 
Iteration: 1016559397, states[0] = -1.107181, states[40]= 0.004789
Saving checkpoint... 
Iteration: 1024732464, states[0] = -87.411753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033569660, states[0] = -11.316994, states[40]= 0.002458
Saving checkpoint... 
Iteration: 1043159252, states[0] = -87.260922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051488862, states[0] = -87.419947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058841111, states[0] = -37.273401, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1066013430, states[0] = 22.760228, states[40]= 0.023123
Saving checkpoint... 
Iteration: 1073062878, states[0] = -4.157108, states[40]= 0.004175
Saving checkpoint... 
Iteration: 1081172176, states[0] = -87.296676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090332145, states[0] = -26.455880, states[40]= 0.000621
Saving checkpoint... 
Iteration: 1099763929, states[0] = 22.639352, states[40]= 0.021164
Saving checkpoint... 
Iteration: 1108253194, states[0] = 32.930912, states[40]= 0.130412
Saving checkpoint... 
Iteration: 1116008058, states[0] = 24.405026, states[40]= 0.071580
Saving checkpoint... 
Iteration: 1123521476, states[0] = 20.380453, states[40]= 0.009145
Saving checkpoint... 
Iteration: 1130835088, states[0] = -30.018969, states[40]= 0.000445
Saving checkpoint... 
Iteration: 1138650465, states[0] = -87.232096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147284134, states[0] = 14.764725, states[40]= 0.006471
Saving checkpoint... 
Iteration: 1156106501, states[0] = -56.566334, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1164924101, states[0] = -87.301539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172602046, states[0] = -50.780507, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1180169477, states[0] = -87.289475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187609857, states[0] = -61.126653, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1195650381, states[0] = -87.231714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203788829, states[0] = 12.276923, states[40]= 0.006160
Saving checkpoint... 
Iteration: 1213008518, states[0] = 24.181538, states[40]= 0.064666
Saving checkpoint... 
Iteration: 1221725966, states[0] = -87.402565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229494321, states[0] = -87.426323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236376464, states[0] = -84.351769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244157961, states[0] = -87.256851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252330245, states[0] = -24.144550, states[40]= 0.000755
Saving checkpoint... 
Iteration: 1261182484, states[0] = -87.321900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270364608, states[0] = -68.090688, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1278959121, states[0] = -87.375855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286783134, states[0] = 15.271499, states[40]= 0.006555
Saving checkpoint... 
Iteration: 1294189990, states[0] = -87.338713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301598701, states[0] = -46.560514, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1309593965, states[0] = -40.727664, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1318138000, states[0] = -87.092025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326567369, states[0] = -8.726757, states[40]= 0.003070
Saving checkpoint... 
Iteration: 1335717761, states[0] = -87.390107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343313098, states[0] = -4.363515, states[40]= 0.004128
Saving checkpoint... 
Iteration: 1351120511, states[0] = -77.434143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358457425, states[0] = -87.372796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366165027, states[0] = -87.277162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374319536, states[0] = -11.172844, states[40]= 0.002490
Saving checkpoint... 
Iteration: 1383036700, states[0] = 13.426044, states[40]= 0.006287
Saving checkpoint... 
Iteration: 1392285001, states[0] = 14.318437, states[40]= 0.006404
Saving checkpoint... 
Iteration: 1400158595, states[0] = -87.258597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407858907, states[0] = -59.811111, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1415218814, states[0] = -87.391675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423696415, states[0] = -87.351944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431935089, states[0] = -87.327726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441057871, states[0] = 0.114630, states[40]= 0.004991
Saving checkpoint... 
Iteration: 1450571050, states[0] = -12.949722, states[40]= 0.002110
Saving checkpoint... 
Iteration: 1459211037, states[0] = -87.378967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467026497, states[0] = 18.383077, states[40]= 0.007446
Saving checkpoint... 
Iteration: 1474359182, states[0] = -60.189413, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1482124747, states[0] = -82.893718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490321217, states[0] = -13.148295, states[40]= 0.002070
Saving checkpoint... 
Iteration: 1499257859, states[0] = 24.513240, states[40]= 0.074762
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.308205
 - CaMKt in component CaMK (millimolar): 0.019400
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.741340
 - nass in component intracellular_ions (millimolar): 6.741440
 - ki in component intracellular_ions (millimolar): 145.215997
 - kss in component intracellular_ions (millimolar): 145.215971
 - cansr in component intracellular_ions (millimolar): 1.425161
 - cajsr in component intracellular_ions (millimolar): 1.207705
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007777
 - hf in component INa (dimensionless): 0.678029
 - hs in component INa (dimensionless): 0.677927
 - j in component INa (dimensionless): 0.677233
 - hsp in component INa (dimensionless): 0.431556
 - jp in component INa (dimensionless): 0.675296
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.387281
 - hLp in component INaL (dimensionless): 0.181526
 - a in component Ito (dimensionless): 0.001040
 - iF in component Ito (dimensionless): 0.999507
 - iS in component Ito (dimensionless): 0.293327
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999507
 - iSp in component Ito (dimensionless): 0.340978
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857569
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991043
 - jca in component ICaL (dimensionless): 0.991392
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004195
 - xrf in component IKr (dimensionless): 0.001743
 - xrs in component IKr (dimensionless): 0.674041
 - xs1 in component IKs (dimensionless): 0.383432
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996908
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:56:17 (30431): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge