𝕏

Task 56110249

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_21_1
Workunit 26646752
Created 4 Jul 2024, 20:49:05 UTC
Sent 5 Jul 2024, 0:04:39 UTC
Report deadline 8 Jul 2024, 0:04:39 UTC
Received 5 Jul 2024, 8:22:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213988
Run time 1 hours 52 min 9 sec
CPU time 1 hours 46 min 16 sec
Validate state Valid
Credit 44.77
Device peak FLOPS 5.10 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_21.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_21_1_r1990524291_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_21_1_r1990524291_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.052829
     * GNaL_b in INaL: 0.005908
     * Gto_b in Ito: 0.083763
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031743
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.162682
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.141560
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032101
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8932488, states[0] = -94.084596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16719196, states[0] = -94.007769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24311687, states[0] = -93.965215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31757651, states[0] = -93.943240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39528656, states[0] = -93.925613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47833282, states[0] = -93.722226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56318197, states[0] = -93.929143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66046639, states[0] = -93.936508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74808019, states[0] = -93.906312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82744733, states[0] = -93.390127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90330595, states[0] = -93.704665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97983827, states[0] = -93.892847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106036621, states[0] = -93.934182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114846015, states[0] = -93.904105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123343439, states[0] = -93.940345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132134453, states[0] = -93.906325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139900883, states[0] = -93.903231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147416196, states[0] = -93.903019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155078850, states[0] = 14.341380, states[40]= 0.001572
Saving checkpoint... 
Iteration: 162763877, states[0] = -93.479979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171598737, states[0] = -93.915463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180731744, states[0] = -93.940320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190005414, states[0] = 31.205178, states[40]= 0.288999
Saving checkpoint... 
Iteration: 198047666, states[0] = -93.917648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205430452, states[0] = -93.854194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212973263, states[0] = -93.885763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221227346, states[0] = -93.926137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230290852, states[0] = -93.587234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238924822, states[0] = -93.919768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247128017, states[0] = -93.905884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254401588, states[0] = -93.909205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261394359, states[0] = -93.920606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269387952, states[0] = -93.909400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278073511, states[0] = -93.924080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287174897, states[0] = -93.905201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296621997, states[0] = -93.914580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305011468, states[0] = 31.105659, states[40]= 0.035458
Saving checkpoint... 
Iteration: 312391512, states[0] = -93.902738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320015594, states[0] = 31.741514, states[40]= 0.008484
Saving checkpoint... 
Iteration: 328436080, states[0] = -93.936834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336971462, states[0] = -93.907916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346256266, states[0] = -93.924860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354424312, states[0] = -93.908627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362957820, states[0] = -93.875489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370049423, states[0] = 25.099589, states[40]= 0.000332
Saving checkpoint... 
Iteration: 378007924, states[0] = -93.903075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386375905, states[0] = -93.920910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395210311, states[0] = -82.350161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404539257, states[0] = -93.906778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413482775, states[0] = -93.934973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420979077, states[0] = -93.935097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428609145, states[0] = -93.930080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436088447, states[0] = -93.930862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443860858, states[0] = -93.921258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452177118, states[0] = -93.904849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461436862, states[0] = -93.918977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470574740, states[0] = -93.923976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478885055, states[0] = -93.920454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486309546, states[0] = -93.922804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493629317, states[0] = -93.929184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501736049, states[0] = -93.911738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509857944, states[0] = -93.902693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518180749, states[0] = -93.937567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527506890, states[0] = 30.337365, states[40]= 0.173666
Saving checkpoint... 
Iteration: 535074254, states[0] = 16.165226, states[40]= 0.001269
Saving checkpoint... 
Iteration: 542677115, states[0] = -50.756619, states[40]= 0.000219
Saving checkpoint... 
Iteration: 550250375, states[0] = -93.416138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558107290, states[0] = -93.929899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566841327, states[0] = -93.909624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575912659, states[0] = -93.937146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584170969, states[0] = -93.912932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591802486, states[0] = -93.910282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599293462, states[0] = -93.910436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606908094, states[0] = -93.908403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615220247, states[0] = -91.606540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623736968, states[0] = -93.924992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632755070, states[0] = -93.438559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641243819, states[0] = -93.924719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649347807, states[0] = -93.909350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656656230, states[0] = -93.913112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664659686, states[0] = -93.904655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673047682, states[0] = -93.916684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681618489, states[0] = -93.913911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690434344, states[0] = -93.856642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698589915, states[0] = -93.930297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706579423, states[0] = -93.914780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713957979, states[0] = -93.917897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721437415, states[0] = -93.918458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729930403, states[0] = -93.901546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738227225, states[0] = -93.939058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746981613, states[0] = -93.906965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755416565, states[0] = -93.839753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763098386, states[0] = -93.928043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770367368, states[0] = -93.775215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778271781, states[0] = -93.939512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786704477, states[0] = -93.911830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795258654, states[0] = -93.454943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804499826, states[0] = -93.906579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812443123, states[0] = -93.901265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819864862, states[0] = -93.902021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827472809, states[0] = -93.900958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835459787, states[0] = -93.875922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844546630, states[0] = -93.905820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853471604, states[0] = -93.934539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861794849, states[0] = -93.909901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869667728, states[0] = -93.904156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877195955, states[0] = -93.903794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885311291, states[0] = -93.651212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893751837, states[0] = -93.923953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902660061, states[0] = -37.664731, states[40]= 0.001224
Saving checkpoint... 
Iteration: 911564251, states[0] = -93.914750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919120749, states[0] = -93.913399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926737117, states[0] = -93.910893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934704126, states[0] = -93.903584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943212697, states[0] = -93.938239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951896095, states[0] = -93.907934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960575012, states[0] = -93.923089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969693761, states[0] = -93.903641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977670140, states[0] = -45.326505, states[40]= 0.000474
Saving checkpoint... 
Iteration: 984971175, states[0] = -93.900668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992287077, states[0] = -93.902515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000446953, states[0] = -93.866324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009050678, states[0] = -93.914896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018177285, states[0] = -93.936386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025983831, states[0] = -93.933749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033332169, states[0] = -93.938418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041262776, states[0] = -93.923291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049415847, states[0] = -93.907418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058341855, states[0] = -93.938174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066843116, states[0] = -93.908624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076060478, states[0] = -93.930707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083706440, states[0] = -93.925186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091171323, states[0] = -93.926453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098380091, states[0] = -93.937136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106362755, states[0] = -93.919917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114819774, states[0] = -93.901921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123470508, states[0] = -93.934057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132282322, states[0] = -93.902296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141133979, states[0] = -93.927755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148420208, states[0] = -93.935790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155865098, states[0] = -93.937434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163599528, states[0] = -93.929027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171881060, states[0] = -93.907761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180296942, states[0] = -93.606174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188385824, states[0] = -93.936796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196923047, states[0] = -93.907014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204921563, states[0] = -93.900710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212455429, states[0] = -93.900373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220078587, states[0] = 14.450940, states[40]= 0.001554
Saving checkpoint... 
Iteration: 1228678267, states[0] = -93.925931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237361098, states[0] = -93.901250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246230200, states[0] = -93.924026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254884441, states[0] = -93.900979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262821397, states[0] = -93.678183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270323628, states[0] = -93.683917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277729776, states[0] = -93.174916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286404068, states[0] = -93.918326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295448160, states[0] = -93.866674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303905771, states[0] = -93.918242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312684346, states[0] = -56.417505, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1320316461, states[0] = -93.664884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327728486, states[0] = -93.110720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335687170, states[0] = -93.936357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344361525, states[0] = -93.907763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353576044, states[0] = -93.929567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362925656, states[0] = -93.847499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371289515, states[0] = -93.921751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379142168, states[0] = -93.912024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387674082, states[0] = -48.387597, states[40]= 0.000310
Saving checkpoint... 
Iteration: 1396259493, states[0] = -93.922717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405422236, states[0] = -93.844149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414247772, states[0] = -93.909737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423236282, states[0] = -93.937931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432405060, states[0] = -93.900430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440471386, states[0] = -93.882218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447934905, states[0] = -93.855656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455749807, states[0] = -93.938072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463250108, states[0] = -93.938060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471272706, states[0] = -93.922122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480284269, states[0] = -93.560813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488680847, states[0] = -93.925333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496759263, states[0] = -93.909351, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.775382
 - CaMKt in component CaMK (millimolar): 0.001583
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.711845
 - nass in component intracellular_ions (millimolar): 6.711969
 - ki in component intracellular_ions (millimolar): 145.149969
 - kss in component intracellular_ions (millimolar): 145.149959
 - cansr in component intracellular_ions (millimolar): 1.833439
 - cajsr in component intracellular_ions (millimolar): 1.833300
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004054
 - hf in component INa (dimensionless): 0.859039
 - hs in component INa (dimensionless): 0.859039
 - j in component INa (dimensionless): 0.859041
 - hsp in component INa (dimensionless): 0.687532
 - jp in component INa (dimensionless): 0.859043
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698479
 - hLp in component INaL (dimensionless): 0.502982
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.997548
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999149
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998689
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005410
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002200
 - xs1 in component IKs (dimensionless): 0.024607
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997618
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:32:53 (30320): called boinc_finish(0)

</stderr_txt>
]]>


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