𝕏

Task 56108516

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0
Workunit 26645886
Created 4 Jul 2024, 20:48:13 UTC
Sent 4 Jul 2024, 23:50:53 UTC
Report deadline 7 Jul 2024, 23:50:53 UTC
Received 5 Jul 2024, 9:08:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239194
Run time 46 min 39 sec
CPU time 33 min 39 sec
Validate state Valid
Credit 44.43
Device peak FLOPS 6.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.79 MB
Peak swap size 5.31 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.116592
     * GNaL_b in INaL: 0.005851
     * Gto_b in Ito: 0.083784
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031914
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162993
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.603326
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032593
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11224592, states[0] = -87.459151, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.116592
     * GNaL_b in INaL: 0.005851
     * Gto_b in Ito: 0.083784
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031914
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162993
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.603326
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032593
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 11224592
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.459151 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 22464994, states[0] = -87.414437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34725849, states[0] = -87.415357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48574045, states[0] = -17.209978, states[40]= 0.001395
Saving checkpoint... 
Iteration: 58963898, states[0] = -87.383443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71007203, states[0] = 25.003599, states[40]= 0.085836
Saving checkpoint... 
Iteration: 91621478, states[0] = -79.215286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104218868, states[0] = -87.383648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118196054, states[0] = -87.342289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130765555, states[0] = 22.272270, states[40]= 0.016390
Saving checkpoint... 
Iteration: 144052686, states[0] = 3.825404, states[40]= 0.005459
Saving checkpoint... 
Iteration: 155351050, states[0] = -49.715165, states[40]= 0.000030
Saving checkpoint... 
Iteration: 168261216, states[0] = 23.369910, states[40]= 0.035786
Saving checkpoint... 
Iteration: 179830559, states[0] = -24.674155, states[40]= 0.000722
Saving checkpoint... 
Iteration: 190166656, states[0] = -87.271419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204081131, states[0] = -25.367736, states[40]= 0.000681
Saving checkpoint... 
Iteration: 217813055, states[0] = -4.404371, states[40]= 0.004120
Saving checkpoint... 
Iteration: 228144242, states[0] = -87.188709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240775532, states[0] = 18.808523, states[40]= 0.007699
Saving checkpoint... 
Iteration: 253989417, states[0] = -87.409911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268095257, states[0] = -42.472690, states[40]= 0.000091
Saving checkpoint... 
Iteration: 293939090, states[0] = -87.326191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306257119, states[0] = 25.091955, states[40]= 0.087189
Saving checkpoint... 
Iteration: 322581148, states[0] = -25.385403, states[40]= 0.000680
Saving checkpoint... 
Iteration: 340373041, states[0] = -81.105524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366354728, states[0] = -54.426532, states[40]= 0.000014
Saving checkpoint... 
Iteration: 404684694, states[0] = -87.316280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443801842, states[0] = 4.405757, states[40]= 0.005515
Saving checkpoint... 
Iteration: 463051903, states[0] = 4.364839, states[40]= 0.005511
Saving checkpoint... 
Iteration: 475466037, states[0] = -87.376665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488113303, states[0] = -66.313501, states[40]= 0.000002
Saving checkpoint... 
Iteration: 499133289, states[0] = -86.759741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512007505, states[0] = 24.821876, states[40]= 0.080406
Saving checkpoint... 
Iteration: 525179875, states[0] = -87.304881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535724253, states[0] = -87.389218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548022077, states[0] = 20.185722, states[40]= 0.008887
Saving checkpoint... 
Iteration: 560618503, states[0] = -74.466455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571574835, states[0] = -17.656643, states[40]= 0.001335
Saving checkpoint... 
Iteration: 583399118, states[0] = -87.215796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595847004, states[0] = -44.624754, states[40]= 0.000066
Saving checkpoint... 
Iteration: 606961383, states[0] = -87.368845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619651650, states[0] = -87.225545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640006222, states[0] = 25.909721, states[40]= 0.103974
Saving checkpoint... 
Iteration: 678234969, states[0] = -87.403848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703462489, states[0] = -87.370611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715906191, states[0] = -87.240461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729647023, states[0] = -87.205879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740263697, states[0] = 22.754543, states[40]= 0.022095
Saving checkpoint... 
Iteration: 752529567, states[0] = 17.007010, states[40]= 0.006969
Saving checkpoint... 
Iteration: 766044191, states[0] = 9.206118, states[40]= 0.005906
Saving checkpoint... 
Iteration: 776348427, states[0] = -46.394121, states[40]= 0.000051
Saving checkpoint... 
Iteration: 789863840, states[0] = -67.122752, states[40]= 0.000002


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.116592
     * GNaL_b in INaL: 0.005851
     * Gto_b in Ito: 0.083784
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031914
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162993
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.603326
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032593
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 789863840
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -67.122752 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 816600479, states[0] = -48.972759, states[40]= 0.000034
Saving checkpoint... 
Iteration: 828865770, states[0] = -70.108134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841316616, states[0] = -8.007209, states[40]= 0.003249
Saving checkpoint... 
Iteration: 850565174, states[0] = -6.491376, states[40]= 0.003624
Saving checkpoint... 
Iteration: 863349125, states[0] = -47.267520, states[40]= 0.000044
Saving checkpoint... 
Iteration: 876645680, states[0] = -87.198086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887394970, states[0] = -87.193393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899329105, states[0] = -22.890592, states[40]= 0.000837
Saving checkpoint... 
Iteration: 910570542, states[0] = -12.463083, states[40]= 0.002210
Saving checkpoint... 
Iteration: 920994908, states[0] = -87.415787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933691664, states[0] = -87.331062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946994763, states[0] = -87.415593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957946429, states[0] = -87.340859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969941896, states[0] = -87.331516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983042537, states[0] = 10.172826, states[40]= 0.005984
Saving checkpoint... 
Iteration: 993842859, states[0] = -39.546438, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1005985504, states[0] = -87.404209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019440207, states[0] = -87.327869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030759445, states[0] = 23.900217, states[40]= 0.052529
Saving checkpoint... 
Iteration: 1043398037, states[0] = -87.210543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056474333, states[0] = -87.388811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067303715, states[0] = 3.124585, states[40]= 0.005386
Saving checkpoint... 
Iteration: 1079854843, states[0] = -54.575244, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1104889627, states[0] = -87.126143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142408214, states[0] = -87.246204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180486433, states[0] = -87.405224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218986441, states[0] = -87.405196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257263003, states[0] = 22.925159, states[40]= 0.025066
Saving checkpoint... 
Iteration: 1295324942, states[0] = -17.786783, states[40]= 0.001319
Saving checkpoint... 
Iteration: 1321118944, states[0] = -75.165688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337380447, states[0] = -86.227795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372037591, states[0] = 12.937681, states[40]= 0.006249
Saving checkpoint... 
Iteration: 1384460115, states[0] = -87.365894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397329879, states[0] = -23.835924, states[40]= 0.000774
Saving checkpoint... 
Iteration: 1407946898, states[0] = -87.341343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421301678, states[0] = 4.516132, states[40]= 0.005526
Saving checkpoint... 
Iteration: 1434224323, states[0] = -87.388416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445517060, states[0] = 21.857338, states[40]= 0.013452
Saving checkpoint... 
Iteration: 1458803127, states[0] = 3.532894, states[40]= 0.005429


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_519_0_r251695297_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.116592
     * GNaL_b in INaL: 0.005851
     * Gto_b in Ito: 0.083784
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031914
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162993
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.603326
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032593
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1458803127
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 3.532894 (After loading)
 - states[40]: 0.005429 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1471304531, states[0] = 2.549049, states[40]= 0.005321
Saving checkpoint... 
Iteration: 1482678016, states[0] = -87.299407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496046487, states[0] = 7.826903, states[40]= 0.005800
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.296688
 - CaMKt in component CaMK (millimolar): 0.019289
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.738518
 - nass in component intracellular_ions (millimolar): 6.738618
 - ki in component intracellular_ions (millimolar): 145.219386
 - kss in component intracellular_ions (millimolar): 145.219360
 - cansr in component intracellular_ions (millimolar): 1.422853
 - cajsr in component intracellular_ions (millimolar): 1.206049
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007786
 - hf in component INa (dimensionless): 0.677616
 - hs in component INa (dimensionless): 0.677514
 - j in component INa (dimensionless): 0.676820
 - hsp in component INa (dimensionless): 0.431092
 - jp in component INa (dimensionless): 0.674891
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.387132
 - hLp in component INaL (dimensionless): 0.181446
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999506
 - iS in component Ito (dimensionless): 0.293513
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999506
 - iSp in component Ito (dimensionless): 0.341183
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857646
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991052
 - jca in component ICaL (dimensionless): 0.991421
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004179
 - xrf in component IKr (dimensionless): 0.001742
 - xrs in component IKr (dimensionless): 0.674510
 - xs1 in component IKs (dimensionless): 0.383105
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996911
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:48:57 (11796): called boinc_finish(0)

</stderr_txt>
]]>


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