𝕏

Task 56108448

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0
Workunit 26645852
Created 4 Jul 2024, 20:48:08 UTC
Sent 4 Jul 2024, 23:50:53 UTC
Report deadline 7 Jul 2024, 23:50:53 UTC
Received 5 Jul 2024, 9:08:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239194
Run time 46 min 4 sec
CPU time 33 min 14 sec
Validate state Valid
Credit 47.06
Device peak FLOPS 6.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.81 MB
Peak swap size 5.34 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0_r894283989_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0_r894283989_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.740964
     * GNaL_b in INaL: 0.005865
     * Gto_b in Ito: 0.084559
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031714
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163816
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.255746
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032479
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12296725, states[0] = -87.042137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25199603, states[0] = -86.849377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38832080, states[0] = -86.976658, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0_r894283989_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0_r894283989_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.740964
     * GNaL_b in INaL: 0.005865
     * Gto_b in Ito: 0.084559
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031714
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163816
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.255746
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032479
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 38832080
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.976658 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 50638192, states[0] = -63.233949, states[40]= 0.000003
Saving checkpoint... 
Iteration: 63628212, states[0] = -50.846923, states[40]= 0.000022
Saving checkpoint... 
Iteration: 76592065, states[0] = -13.642037, states[40]= 0.001635
Saving checkpoint... 
Iteration: 88200857, states[0] = -86.768603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101106426, states[0] = -27.531109, states[40]= 0.000536
Saving checkpoint... 
Iteration: 122208251, states[0] = -86.774532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133593880, states[0] = -14.759820, states[40]= 0.001464
Saving checkpoint... 
Iteration: 146740011, states[0] = -86.826898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159892351, states[0] = -86.945344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172707473, states[0] = -86.769029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183128762, states[0] = -49.945380, states[40]= 0.000025
Saving checkpoint... 
Iteration: 196179968, states[0] = -86.708282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209119362, states[0] = -40.074459, states[40]= 0.000116
Saving checkpoint... 
Iteration: 219382301, states[0] = -86.940311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232037444, states[0] = 16.817446, states[40]= 0.004968
Saving checkpoint... 
Iteration: 245115735, states[0] = -36.396742, states[40]= 0.000196
Saving checkpoint... 
Iteration: 255738405, states[0] = -86.821945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268317866, states[0] = -86.906584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281663511, states[0] = -86.180128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295941318, states[0] = -86.956877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320333293, states[0] = -86.916502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332368222, states[0] = -86.934292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349543906, states[0] = 14.379966, states[40]= 0.004795
Saving checkpoint... 
Iteration: 365530643, states[0] = 19.163419, states[40]= 0.005416
Saving checkpoint... 
Iteration: 392060614, states[0] = 7.511164, states[40]= 0.004670
Saving checkpoint... 
Iteration: 429669798, states[0] = -86.605657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467767499, states[0] = -86.860602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487505004, states[0] = 26.489771, states[40]= 0.144281
Saving checkpoint... 
Iteration: 500250772, states[0] = -86.839549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513218811, states[0] = -86.788910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524051780, states[0] = 11.248730, states[40]= 0.004729
Saving checkpoint... 
Iteration: 537003778, states[0] = 29.555731, states[40]= 0.165077
Saving checkpoint... 
Iteration: 549654802, states[0] = -82.216188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559809868, states[0] = -86.900477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572336841, states[0] = -86.918402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585330018, states[0] = -86.914295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596361953, states[0] = -86.931323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608799865, states[0] = -86.892475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622308326, states[0] = -86.899255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633332439, states[0] = -86.915746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646246952, states[0] = -86.834140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666672313, states[0] = -86.654477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704742758, states[0] = -86.828048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730207047, states[0] = -86.766603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743230296, states[0] = -86.808595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755791843, states[0] = -86.885382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766657449, states[0] = -84.226737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779315675, states[0] = -86.904593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791999486, states[0] = -86.965957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802888855, states[0] = -86.941965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815753363, states[0] = -86.842809, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0_r894283989_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_1000-conf_19_0_r894283989_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.740964
     * GNaL_b in INaL: 0.005865
     * Gto_b in Ito: 0.084559
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031714
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163816
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.255746
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032479
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 815753363
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.842809 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 842000623, states[0] = 35.963525, states[40]= 0.006488
Saving checkpoint... 
Iteration: 854093653, states[0] = -14.380018, states[40]= 0.001517
Saving checkpoint... 
Iteration: 867001876, states[0] = 39.013697, states[40]= 0.112411
Saving checkpoint... 
Iteration: 878125421, states[0] = -46.329973, states[40]= 0.000045
Saving checkpoint... 
Iteration: 891811069, states[0] = -86.901143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904685357, states[0] = -86.721745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915119556, states[0] = -40.250753, states[40]= 0.000113
Saving checkpoint... 
Iteration: 927419207, states[0] = -86.951145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939131560, states[0] = -52.948118, states[40]= 0.000015
Saving checkpoint... 
Iteration: 949287701, states[0] = -86.881410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962264221, states[0] = -86.856394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975863785, states[0] = -86.931878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986463368, states[0] = -86.960585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999936188, states[0] = -86.955221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012269493, states[0] = -86.862494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023107400, states[0] = -28.066553, states[40]= 0.000512
Saving checkpoint... 
Iteration: 1035868099, states[0] = -86.933725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049326652, states[0] = -86.911839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060667622, states[0] = -86.527752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074171868, states[0] = -86.647581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087244198, states[0] = -86.829877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097446761, states[0] = -86.957402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110042459, states[0] = 14.939203, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1135628177, states[0] = -49.265916, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1172919676, states[0] = -86.951092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210854620, states[0] = -86.927425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249912838, states[0] = -86.949185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288276022, states[0] = -86.869460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327211657, states[0] = -86.775052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353347748, states[0] = -86.923852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369112415, states[0] = -33.066294, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1402723569, states[0] = -86.796717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414522692, states[0] = 21.390502, states[40]= 0.006979
Saving checkpoint... 
Iteration: 1427263026, states[0] = -86.854624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437650471, states[0] = -77.079310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451637744, states[0] = -60.001868, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1465245501, states[0] = -86.831485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476616387, states[0] = -37.043634, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1488753689, states[0] = -86.842758, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.841390
 - CaMKt in component CaMK (millimolar): 0.006774
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.405322
 - nass in component intracellular_ions (millimolar): 6.405379
 - ki in component intracellular_ions (millimolar): 145.578367
 - kss in component intracellular_ions (millimolar): 145.578348
 - cansr in component intracellular_ions (millimolar): 1.294100
 - cajsr in component intracellular_ions (millimolar): 1.256269
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008151
 - hf in component INa (dimensionless): 0.661057
 - hs in component INa (dimensionless): 0.661046
 - j in component INa (dimensionless): 0.660982
 - hsp in component INa (dimensionless): 0.413168
 - jp in component INa (dimensionless): 0.660938
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466039
 - hLp in component INaL (dimensionless): 0.240622
 - a in component Ito (dimensionless): 0.001074
 - iF in component Ito (dimensionless): 0.999466
 - iS in component Ito (dimensionless): 0.577998
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999466
 - iSp in component Ito (dimensionless): 0.632388
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934885
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001528
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.406910
 - xs1 in component IKs (dimensionless): 0.243076
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997021
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:08:43 (34196): called boinc_finish(0)

</stderr_txt>
]]>


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