𝕏

Task 56106608

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_750-conf_417_1
Workunit 26644935
Created 4 Jul 2024, 20:47:15 UTC
Sent 4 Jul 2024, 23:36:48 UTC
Report deadline 7 Jul 2024, 23:36:48 UTC
Received 5 Jul 2024, 6:28:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 16 min 41 sec
CPU time 2 hours 12 min
Validate state Valid
Credit 43.47
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.53 MB
Peak swap size 2.35 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_750-conf_417.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_750-conf_417_1_r1302253282_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Schmidt_750-conf_417_1_r1302253282_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.818493
     * GNaL_b in INaL: 0.005739
     * Gto_b in Ito: 0.084419
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031828
     * GKs_b in IKs: 0.001929
     * GK1_b in IK1: 0.162709
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.460723
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032167
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11251773, states[0] = 36.353722, states[40]= 0.838292
Saving checkpoint... 
Iteration: 22500060, states[0] = -77.251850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33720509, states[0] = -84.618115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44955014, states[0] = -84.592418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56175727, states[0] = -84.534034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67440067, states[0] = -84.563347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78702946, states[0] = -84.585778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89977067, states[0] = -84.620255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101276738, states[0] = 29.219792, states[40]= 0.000165
Saving checkpoint... 
Iteration: 112550898, states[0] = 18.680638, states[40]= 0.000028
Saving checkpoint... 
Iteration: 123657044, states[0] = -84.482254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134735467, states[0] = -27.186846, states[40]= 0.000207
Saving checkpoint... 
Iteration: 145970678, states[0] = -10.893974, states[40]= 0.000323
Saving checkpoint... 
Iteration: 157181020, states[0] = 16.117489, states[40]= 0.000043
Saving checkpoint... 
Iteration: 168406273, states[0] = 27.540837, states[40]= 0.000037
Saving checkpoint... 
Iteration: 179583951, states[0] = -84.592376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190809437, states[0] = -84.547985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 202033198, states[0] = -84.483806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213251261, states[0] = -84.372598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224480547, states[0] = -84.273514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235684081, states[0] = -83.942610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246863651, states[0] = -30.568695, states[40]= 0.000190
Saving checkpoint... 
Iteration: 258107359, states[0] = -23.825096, states[40]= 0.000209
Saving checkpoint... 
Iteration: 269321467, states[0] = 7.746758, states[40]= 0.000147
Saving checkpoint... 
Iteration: 280537690, states[0] = 24.856341, states[40]= 0.000012
Saving checkpoint... 
Iteration: 291625423, states[0] = -84.367550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302863674, states[0] = -84.313765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314068877, states[0] = -84.027186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325227485, states[0] = -18.450147, states[40]= 0.000224
Saving checkpoint... 
Iteration: 336473365, states[0] = -13.833505, states[40]= 0.000278
Saving checkpoint... 
Iteration: 347713825, states[0] = -4.166249, states[40]= 0.000364
Saving checkpoint... 
Iteration: 358940529, states[0] = 11.094131, states[40]= 0.000094
Saving checkpoint... 
Iteration: 370149042, states[0] = 30.096146, states[40]= 0.000422
Saving checkpoint... 
Iteration: 381327507, states[0] = -84.578124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392551210, states[0] = -84.526206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403785036, states[0] = -84.485128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415024195, states[0] = -84.452694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426266655, states[0] = -84.427427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437518357, states[0] = -84.433071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448596837, states[0] = -12.140151, states[40]= 0.000304
Saving checkpoint... 
Iteration: 459839608, states[0] = -4.855546, states[40]= 0.000367
Saving checkpoint... 
Iteration: 471085254, states[0] = -1.248634, states[40]= 0.000331
Saving checkpoint... 
Iteration: 482328905, states[0] = 3.203915, states[40]= 0.000241
Saving checkpoint... 
Iteration: 493535707, states[0] = 25.716908, states[40]= 0.000014
Saving checkpoint... 
Iteration: 504634076, states[0] = -84.398313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515580487, states[0] = -84.580508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526854839, states[0] = -84.614642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538072092, states[0] = -84.565795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549303987, states[0] = -84.529498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560504317, states[0] = -84.378546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571689984, states[0] = -83.989959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582880969, states[0] = -48.811648, states[40]= 0.000035
Saving checkpoint... 
Iteration: 594060676, states[0] = 13.705484, states[40]= 0.000064
Saving checkpoint... 
Iteration: 605157963, states[0] = -84.475472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616369600, states[0] = -84.335741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627575379, states[0] = -84.071667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638756911, states[0] = -49.815898, states[40]= 0.000030
Saving checkpoint... 
Iteration: 649990914, states[0] = -32.951309, states[40]= 0.000169
Saving checkpoint... 
Iteration: 661184934, states[0] = 14.096692, states[40]= 0.000060
Saving checkpoint... 
Iteration: 672413021, states[0] = 24.713808, states[40]= 0.000011
Saving checkpoint... 
Iteration: 683580911, states[0] = -84.578030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694787931, states[0] = -84.487528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706027110, states[0] = -84.456256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717192571, states[0] = -84.008707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728435234, states[0] = -83.944232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739700499, states[0] = -84.070388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750933659, states[0] = -83.928164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762011472, states[0] = 31.299525, states[40]= 0.035996
Saving checkpoint... 
Iteration: 773249139, states[0] = -84.631142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 784507372, states[0] = 30.098443, states[40]= 0.153933
Saving checkpoint... 
Iteration: 795776320, states[0] = 29.371367, states[40]= 0.000191
Saving checkpoint... 
Iteration: 807018871, states[0] = 31.337777, states[40]= 0.002609
Saving checkpoint... 
Iteration: 818257424, states[0] = 30.112228, states[40]= 0.151133
Saving checkpoint... 
Iteration: 829516838, states[0] = 31.596755, states[40]= 0.005358
Saving checkpoint... 
Iteration: 840686293, states[0] = -84.539499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851916127, states[0] = -84.492975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 863168652, states[0] = -84.499192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874338130, states[0] = -84.156822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885562385, states[0] = -83.961106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896682819, states[0] = 15.200556, states[40]= 0.000050
Saving checkpoint... 
Iteration: 907902966, states[0] = 28.797542, states[40]= 0.000108
Saving checkpoint... 
Iteration: 918991601, states[0] = -84.316031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930190957, states[0] = -83.991171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941419585, states[0] = -83.549489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952617414, states[0] = -34.523251, states[40]= 0.000152
Saving checkpoint... 
Iteration: 963865962, states[0] = -32.992745, states[40]= 0.000168
Saving checkpoint... 
Iteration: 974983695, states[0] = -84.610831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986147401, states[0] = -84.436088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997359041, states[0] = -84.277116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008612103, states[0] = -84.292466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019852939, states[0] = -84.243914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031102202, states[0] = -84.239577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042314967, states[0] = -83.980610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053559182, states[0] = -83.927512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064656934, states[0] = 27.285333, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1075700058, states[0] = -84.060529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086906384, states[0] = -78.352345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098144762, states[0] = -64.267304, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1109332665, states[0] = 0.667862, states[40]= 0.000296
Saving checkpoint... 
Iteration: 1120539969, states[0] = 23.849746, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1131702682, states[0] = -84.564285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142917606, states[0] = -84.491257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154163447, states[0] = -84.480208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165324087, states[0] = -84.051415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176522120, states[0] = -67.191514, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1187737734, states[0] = -29.567070, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1198924520, states[0] = 19.367312, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1210164116, states[0] = 24.232537, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1221488872, states[0] = -30.774481, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1232542469, states[0] = -84.489212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243765654, states[0] = -84.408366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254958805, states[0] = -84.120262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266163500, states[0] = -82.569884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277429880, states[0] = -83.873855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288489182, states[0] = -84.611157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299706734, states[0] = -84.567751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310950109, states[0] = -84.556532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322189296, states[0] = -84.536407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333418897, states[0] = -84.490906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344665953, states[0] = -84.483195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355914762, states[0] = -84.479872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367177781, states[0] = -84.511352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378428754, states[0] = -84.513316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389517391, states[0] = -61.415038, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1400740269, states[0] = -32.248051, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1411963524, states[0] = -3.884511, states[40]= 0.000362
Saving checkpoint... 
Iteration: 1423181303, states[0] = 15.984155, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1434456742, states[0] = 1.318610, states[40]= 0.000282
Saving checkpoint... 
Iteration: 1445663536, states[0] = 24.492120, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1456875787, states[0] = 33.565280, states[40]= 0.265730
Saving checkpoint... 
Iteration: 1468087190, states[0] = -84.573029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479309970, states[0] = -84.524733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490529227, states[0] = -84.447770, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.494183
 - CaMKt in component CaMK (millimolar): 0.029750
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.750504
 - nass in component intracellular_ions (millimolar): 6.750646
 - ki in component intracellular_ions (millimolar): 144.960941
 - kss in component intracellular_ions (millimolar): 144.960915
 - cansr in component intracellular_ions (millimolar): 1.947775
 - cajsr in component intracellular_ions (millimolar): 1.781558
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.010316
 - hf in component INa (dimensionless): 0.570119
 - hs in component INa (dimensionless): 0.570014
 - j in component INa (dimensionless): 0.569455
 - hsp in component INa (dimensionless): 0.323490
 - jp in component INa (dimensionless): 0.569037
 - mL in component INaL (dimensionless): 0.000358
 - hL in component INaL (dimensionless): 0.361017
 - hLp in component INaL (dimensionless): 0.160770
 - a in component Ito (dimensionless): 0.001258
 - iF in component Ito (dimensionless): 0.999194
 - iS in component Ito (dimensionless): 0.416594
 - ap in component Ito (dimensionless): 0.000641
 - iFp in component Ito (dimensionless): 0.999194
 - iSp in component Ito (dimensionless): 0.453310
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.864182
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.997993
 - jca in component ICaL (dimensionless): 0.999318
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004881
 - xrf in component IKr (dimensionless): 0.000103
 - xrs in component IKr (dimensionless): 0.628654
 - xs1 in component IKs (dimensionless): 0.354765
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996802
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:23:09 (41900): called boinc_finish(0)

</stderr_txt>
]]>


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