𝕏

Task 56103848

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_515_1
Workunit 26643556
Created 4 Jul 2024, 20:45:47 UTC
Sent 4 Jul 2024, 23:18:34 UTC
Report deadline 7 Jul 2024, 23:18:34 UTC
Received 5 Jul 2024, 10:57:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233371
Run time 1 hours 24 min 3 sec
CPU time 51 min 24 sec
Validate state Valid
Credit 44.32
Device peak FLOPS 7.10 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.13 MB
Peak swap size 10.95 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_515.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_515_1_r877118474_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_3000-conf_515_1_r877118474_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.988657
     * GNaL_b in INaL: 0.005906
     * Gto_b in Ito: 0.084021
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031794
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.162879
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.305236
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033631
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10946428, states[0] = -94.085141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21732540, states[0] = -94.073008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32237691, states[0] = -94.047672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43211720, states[0] = -94.021657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53999369, states[0] = -94.007782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65384558, states[0] = -94.029720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76195142, states[0] = -94.016261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86650359, states[0] = -94.017867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97677681, states[0] = -55.211768, states[40]= 0.000101
Saving checkpoint... 
Iteration: 108374642, states[0] = -93.891939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119210108, states[0] = -94.030975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130105185, states[0] = -94.019493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141023417, states[0] = 31.316730, states[40]= 0.000634
Saving checkpoint... 
Iteration: 152060521, states[0] = -94.014924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163497266, states[0] = -94.005018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174182290, states[0] = -59.021740, states[40]= 0.000055
Saving checkpoint... 
Iteration: 184768249, states[0] = -93.619292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195905184, states[0] = -94.027700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206400589, states[0] = -94.027837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217395306, states[0] = -94.008059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228161481, states[0] = -42.069028, states[40]= 0.000658
Saving checkpoint... 
Iteration: 239029366, states[0] = -94.006160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249618897, states[0] = -94.024528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260493616, states[0] = -94.023881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270986791, states[0] = -94.024139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282011118, states[0] = 30.981374, states[40]= 0.040028
Saving checkpoint... 
Iteration: 292513880, states[0] = 31.478684, states[40]= 0.015346
Saving checkpoint... 
Iteration: 303362952, states[0] = -93.873502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314649799, states[0] = -94.016998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325270067, states[0] = -94.012168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336698080, states[0] = -94.029904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347742887, states[0] = -94.013137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358837001, states[0] = -93.825644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369947595, states[0] = -94.025466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380548214, states[0] = -94.021134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391244519, states[0] = -94.012934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402799323, states[0] = -94.030135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413928192, states[0] = -94.006351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425526586, states[0] = -94.021929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436266187, states[0] = -94.011959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447489059, states[0] = -93.989745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458156188, states[0] = -94.027362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469197680, states[0] = -94.014537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480226281, states[0] = -93.356123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491149699, states[0] = -94.026770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501947310, states[0] = -94.025055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513116692, states[0] = -6.744618, states[40]= 0.003054
Saving checkpoint... 
Iteration: 523969875, states[0] = -93.979526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535133299, states[0] = -94.016984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546349910, states[0] = -93.850304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557065688, states[0] = -94.014779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567948708, states[0] = -94.024787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578751598, states[0] = -94.012060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589664500, states[0] = -44.480850, states[40]= 0.000482
Saving checkpoint... 
Iteration: 599898767, states[0] = -94.006717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610061342, states[0] = -94.019830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620001393, states[0] = -93.994690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630693947, states[0] = -94.028819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641602238, states[0] = -94.017964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652232767, states[0] = -94.012556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662768149, states[0] = -94.011159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673522657, states[0] = 31.408526, states[40]= 0.000799
Saving checkpoint... 
Iteration: 684286762, states[0] = -93.687841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695050699, states[0] = -94.010794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705947832, states[0] = -94.024381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716553415, states[0] = -94.019833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726968960, states[0] = -94.023436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738179292, states[0] = -56.527985, states[40]= 0.000082
Saving checkpoint... 
Iteration: 748751490, states[0] = -93.543478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759361274, states[0] = -93.869308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770060897, states[0] = -94.013025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781059407, states[0] = -94.019366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791766117, states[0] = -94.010823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801991719, states[0] = -94.022229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813320535, states[0] = -93.786765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824066587, states[0] = -94.014120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834976511, states[0] = -94.022771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846044213, states[0] = 26.298242, states[40]= 0.000250
Saving checkpoint... 
Iteration: 856855689, states[0] = -93.859594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867840583, states[0] = -94.027701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878815025, states[0] = -94.008729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889704490, states[0] = -82.700211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900236740, states[0] = -93.467965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909688948, states[0] = -94.027733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921092326, states[0] = 7.649728, states[40]= 0.002705
Saving checkpoint... 
Iteration: 932031619, states[0] = -94.004650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943073547, states[0] = -94.018235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953963439, states[0] = -94.003507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964847720, states[0] = -93.844893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975844307, states[0] = -94.027250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986806122, states[0] = -94.008707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998088464, states[0] = -94.017773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009098199, states[0] = -94.016961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020013953, states[0] = 31.488553, states[40]= 0.014962
Saving checkpoint... 
Iteration: 1030876630, states[0] = -93.891741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041858455, states[0] = -94.026615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052707629, states[0] = -94.012269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063562294, states[0] = 20.037026, states[40]= 0.000700
Saving checkpoint... 
Iteration: 1074438994, states[0] = -93.957271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085120317, states[0] = -94.022023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095974017, states[0] = -94.022042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106781922, states[0] = -94.009218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117658370, states[0] = -39.608369, states[40]= 0.000887
Saving checkpoint... 
Iteration: 1128459030, states[0] = -93.971075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139370997, states[0] = -94.025897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149412186, states[0] = -93.933566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160765651, states[0] = -94.009659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170963178, states[0] = -94.022257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182342328, states[0] = -93.833807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193096488, states[0] = -94.018454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203448111, states[0] = -93.963552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214735409, states[0] = -94.010651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224842022, states[0] = -94.026519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235646104, states[0] = -94.014203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246797502, states[0] = -93.721334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257552023, states[0] = -94.009330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268378783, states[0] = -94.025221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279639528, states[0] = -25.174064, states[40]= 0.002223
Saving checkpoint... 
Iteration: 1290379266, states[0] = -93.894563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301534175, states[0] = -94.018796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312445865, states[0] = -94.002908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323799226, states[0] = -94.027192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334390220, states[0] = -94.024607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345728115, states[0] = -93.387840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356837403, states[0] = -94.026225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367750604, states[0] = -94.009572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378466873, states[0] = -94.002040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389583768, states[0] = -94.015701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400304299, states[0] = -94.026856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411047198, states[0] = -94.017880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421857711, states[0] = -94.005476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432737010, states[0] = -93.467802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443454495, states[0] = -93.967133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454027412, states[0] = -94.001644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464868736, states[0] = -94.024931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475805532, states[0] = -94.007162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486234228, states[0] = -94.009828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497300423, states[0] = -93.729488, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.876605
 - CaMKt in component CaMK (millimolar): 0.003116
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.764750
 - nass in component intracellular_ions (millimolar): 6.764871
 - ki in component intracellular_ions (millimolar): 145.087693
 - kss in component intracellular_ions (millimolar): 145.087681
 - cansr in component intracellular_ions (millimolar): 1.833680
 - cajsr in component intracellular_ions (millimolar): 1.833499
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.004013
 - hf in component INa (dimensionless): 0.861041
 - hs in component INa (dimensionless): 0.861042
 - j in component INa (dimensionless): 0.861050
 - hsp in component INa (dimensionless): 0.691100
 - jp in component INa (dimensionless): 0.861054
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701382
 - hLp in component INaL (dimensionless): 0.503143
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.968737
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.984148
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990120
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005005
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030112
 - xs1 in component IKs (dimensionless): 0.072826
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997594
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:57:20 (534870): called boinc_finish(0)

</stderr_txt>
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