𝕏

Task 56103211

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_714_0
Workunit 26643238
Created 4 Jul 2024, 20:45:32 UTC
Sent 4 Jul 2024, 23:17:06 UTC
Report deadline 7 Jul 2024, 23:17:06 UTC
Received 6 Jul 2024, 18:24:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215347
Run time 4 hours 10 min 11 sec
CPU time 4 hours 6 min 26 sec
Validate state Valid
Credit 42.72
Device peak FLOPS 3.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak disk usage 0.18 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_714.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_714_0_r1644075260_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_500-conf_714_0_r1644075260_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.377006
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.084157
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031820
     * GKs_b in IKs: 0.001942
     * GK1_b in IK1: 0.163137
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.174077
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032585
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10906369, states[0] = -87.329717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21892415, states[0] = -87.231188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32959768, states[0] = -87.399689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43891808, states[0] = -87.193673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54856557, states[0] = -57.207956, states[40]= 0.000009
Saving checkpoint... 
Iteration: 65783501, states[0] = 15.016479, states[40]= 0.006521
Saving checkpoint... 
Iteration: 76624298, states[0] = -82.635947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87357467, states[0] = -58.061249, states[40]= 0.000008
Saving checkpoint... 
Iteration: 98222919, states[0] = -87.399164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109282137, states[0] = 15.757097, states[40]= 0.006648
Saving checkpoint... 
Iteration: 120058410, states[0] = -0.341284, states[40]= 0.004917
Saving checkpoint... 
Iteration: 130428872, states[0] = -87.312563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140474906, states[0] = -87.400152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150712295, states[0] = -87.380229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161303897, states[0] = 3.033683, states[40]= 0.005369
Saving checkpoint... 
Iteration: 171838028, states[0] = -33.588828, states[40]= 0.000300
Saving checkpoint... 
Iteration: 182777404, states[0] = 17.995325, states[40]= 0.007273
Saving checkpoint... 
Iteration: 193762297, states[0] = 23.057096, states[40]= 0.028619
Saving checkpoint... 
Iteration: 204884457, states[0] = -86.881928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215835686, states[0] = -30.760254, states[40]= 0.000412
Saving checkpoint... 
Iteration: 226766232, states[0] = 22.067704, states[40]= 0.014854
Saving checkpoint... 
Iteration: 237673104, states[0] = -87.297189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248578965, states[0] = -22.599240, states[40]= 0.000858
Saving checkpoint... 
Iteration: 259451368, states[0] = -87.360148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270217766, states[0] = -87.388595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280999263, states[0] = -87.430359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291978020, states[0] = -87.403845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302696310, states[0] = -87.350197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313675564, states[0] = -87.303348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324541223, states[0] = 10.945207, states[40]= 0.006035
Saving checkpoint... 
Iteration: 335589525, states[0] = -35.381464, states[40]= 0.000240
Saving checkpoint... 
Iteration: 346548116, states[0] = 6.849352, states[40]= 0.005714
Saving checkpoint... 
Iteration: 357298820, states[0] = 6.406831, states[40]= 0.005679
Saving checkpoint... 
Iteration: 367947814, states[0] = -87.353130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379048691, states[0] = 6.488321, states[40]= 0.005685
Saving checkpoint... 
Iteration: 389931595, states[0] = -87.317966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400865396, states[0] = -69.318142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411767349, states[0] = 21.750688, states[40]= 0.012943
Saving checkpoint... 
Iteration: 422650400, states[0] = -87.229636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433615891, states[0] = -70.094677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444600830, states[0] = -49.256628, states[40]= 0.000033
Saving checkpoint... 
Iteration: 455272452, states[0] = 20.035693, states[40]= 0.008670
Saving checkpoint... 
Iteration: 466291110, states[0] = 11.009225, states[40]= 0.006040
Saving checkpoint... 
Iteration: 477040991, states[0] = 11.076456, states[40]= 0.006046
Saving checkpoint... 
Iteration: 487738413, states[0] = -87.417406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498709932, states[0] = -87.375417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509644949, states[0] = -87.201776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520511400, states[0] = 23.278591, states[40]= 0.034346
Saving checkpoint... 
Iteration: 531504198, states[0] = 29.427215, states[40]= 0.134985
Saving checkpoint... 
Iteration: 542228858, states[0] = -87.404758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552997802, states[0] = -87.428452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563866076, states[0] = -70.386141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574772252, states[0] = 20.110861, states[40]= 0.008760
Saving checkpoint... 
Iteration: 585836488, states[0] = -31.724887, states[40]= 0.000371
Saving checkpoint... 
Iteration: 596726684, states[0] = -87.401641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607636072, states[0] = -87.000238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618600040, states[0] = -48.259378, states[40]= 0.000038
Saving checkpoint... 
Iteration: 629418843, states[0] = -87.285555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640413393, states[0] = -87.270509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651364734, states[0] = -68.289617, states[40]= 0.000002
Saving checkpoint... 
Iteration: 662304725, states[0] = 2.454183, states[40]= 0.005304
Saving checkpoint... 
Iteration: 672884416, states[0] = -86.877222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683741969, states[0] = -87.421555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694705329, states[0] = -87.367061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705711943, states[0] = -87.378639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716749615, states[0] = -87.430299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727668215, states[0] = -87.283763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738743873, states[0] = -87.423757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749618043, states[0] = -73.525300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760285504, states[0] = 14.061001, states[40]= 0.006368
Saving checkpoint... 
Iteration: 770983421, states[0] = -87.410711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781570547, states[0] = -12.366413, states[40]= 0.002229
Saving checkpoint... 
Iteration: 792062745, states[0] = -4.040705, states[40]= 0.004199
Saving checkpoint... 
Iteration: 802949521, states[0] = -87.356033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813737762, states[0] = -87.416260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824329468, states[0] = -23.212121, states[40]= 0.000815
Saving checkpoint... 
Iteration: 835194785, states[0] = -87.346556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845877875, states[0] = -85.200599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856402490, states[0] = -87.236840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867157587, states[0] = -87.253262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877650417, states[0] = -87.229233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888121566, states[0] = -78.973608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898830972, states[0] = -25.045381, states[40]= 0.000700
Saving checkpoint... 
Iteration: 909560178, states[0] = -1.764037, states[40]= 0.004668
Saving checkpoint... 
Iteration: 920077010, states[0] = -20.205544, states[40]= 0.001054
Saving checkpoint... 
Iteration: 930675646, states[0] = -87.302921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941579441, states[0] = -23.178999, states[40]= 0.000817
Saving checkpoint... 
Iteration: 952299828, states[0] = 5.764328, states[40]= 0.005627
Saving checkpoint... 
Iteration: 962763102, states[0] = 22.864238, states[40]= 0.024519
Saving checkpoint... 
Iteration: 973385514, states[0] = -86.964539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983872994, states[0] = -80.896781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994278758, states[0] = 17.385683, states[40]= 0.007054
Saving checkpoint... 
Iteration: 1005080354, states[0] = -24.292544, states[40]= 0.000745
Saving checkpoint... 
Iteration: 1015895119, states[0] = -87.202444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026785444, states[0] = 14.092498, states[40]= 0.006372
Saving checkpoint... 
Iteration: 1037663887, states[0] = -87.271499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048557364, states[0] = 0.501642, states[40]= 0.005047
Saving checkpoint... 
Iteration: 1059453409, states[0] = -87.363159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070317750, states[0] = -9.157117, states[40]= 0.002964
Saving checkpoint... 
Iteration: 1081293236, states[0] = 9.790176, states[40]= 0.005939
Saving checkpoint... 
Iteration: 1092282695, states[0] = 15.497583, states[40]= 0.006595
Saving checkpoint... 
Iteration: 1103143564, states[0] = -87.189970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113947640, states[0] = -87.352024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124850325, states[0] = -48.617565, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1135683307, states[0] = -87.321211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146337108, states[0] = -32.471069, states[40]= 0.000341
Saving checkpoint... 
Iteration: 1157323301, states[0] = -15.670624, states[40]= 0.001618
Saving checkpoint... 
Iteration: 1168287217, states[0] = 13.153656, states[40]= 0.006254
Saving checkpoint... 
Iteration: 1179225385, states[0] = -87.399183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190088704, states[0] = -34.392161, states[40]= 0.000272
Saving checkpoint... 
Iteration: 1200895833, states[0] = -87.206934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211729250, states[0] = -87.404622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222517981, states[0] = 21.562170, states[40]= 0.012083
Saving checkpoint... 
Iteration: 1233355052, states[0] = -54.676843, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1244229852, states[0] = -87.405420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255125659, states[0] = -83.698280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266188342, states[0] = -87.332446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277227780, states[0] = -87.402503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288078017, states[0] = -21.437974, states[40]= 0.000947
Saving checkpoint... 
Iteration: 1298976745, states[0] = -87.401014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309957671, states[0] = -87.370638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320798521, states[0] = 6.595948, states[40]= 0.005694
Saving checkpoint... 
Iteration: 1331658397, states[0] = -87.255237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342237804, states[0] = -87.415776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353160252, states[0] = -87.260724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364156902, states[0] = -87.250653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375063990, states[0] = -5.227585, states[40]= 0.003926
Saving checkpoint... 
Iteration: 1385979202, states[0] = -87.404378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396732454, states[0] = -87.408791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407621784, states[0] = -79.281008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418679807, states[0] = -87.312652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429686852, states[0] = -87.328979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440444587, states[0] = -87.345533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450924614, states[0] = -87.299784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461855536, states[0] = -55.310137, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1472757193, states[0] = 24.963945, states[40]= 0.085936
Saving checkpoint... 
Iteration: 1483766264, states[0] = 22.059450, states[40]= 0.014791
Saving checkpoint... 
Iteration: 1494559172, states[0] = -0.928657, states[40]= 0.004818
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.305680
 - CaMKt in component CaMK (millimolar): 0.019349
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.746497
 - nass in component intracellular_ions (millimolar): 6.746597
 - ki in component intracellular_ions (millimolar): 145.211113
 - kss in component intracellular_ions (millimolar): 145.211086
 - cansr in component intracellular_ions (millimolar): 1.423963
 - cajsr in component intracellular_ions (millimolar): 1.206789
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007779
 - hf in component INa (dimensionless): 0.677938
 - hs in component INa (dimensionless): 0.677836
 - j in component INa (dimensionless): 0.677141
 - hsp in component INa (dimensionless): 0.431454
 - jp in component INa (dimensionless): 0.675202
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.387183
 - hLp in component INaL (dimensionless): 0.181456
 - a in component Ito (dimensionless): 0.001040
 - iF in component Ito (dimensionless): 0.999507
 - iS in component Ito (dimensionless): 0.293324
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999507
 - iSp in component Ito (dimensionless): 0.340964
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857537
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991044
 - jca in component ICaL (dimensionless): 0.991395
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004186
 - xrf in component IKr (dimensionless): 0.001746
 - xrs in component IKr (dimensionless): 0.673731
 - xs1 in component IKs (dimensionless): 0.383411
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996908
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:50:37 (16994): called boinc_finish(0)

</stderr_txt>
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