𝕏

Task 56103168

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_514_1
Workunit 26643216
Created 4 Jul 2024, 20:45:27 UTC
Sent 4 Jul 2024, 23:15:06 UTC
Report deadline 7 Jul 2024, 23:15:06 UTC
Received 5 Jul 2024, 10:16:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227546
Run time 1 hours 6 min 20 sec
CPU time 45 min 31 sec
Validate state Valid
Credit 50.30
Device peak FLOPS 4.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 8.35 MB
Peak swap size 32.86 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_514.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_514_1_r78172260_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Pieske_333-conf_514_1_r78172260_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.228524
     * GNaL_b in INaL: 0.005767
     * Gto_b in Ito: 0.085450
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031832
     * GKs_b in IKs: 0.001923
     * GK1_b in IK1: 0.163048
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.402077
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033589
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 19347142, states[0] = 20.275130, states[40]= 0.017883
Saving checkpoint... 
Iteration: 39877600, states[0] = -0.642889, states[40]= 0.005850
Saving checkpoint... 
Iteration: 55900947, states[0] = -33.794136, states[40]= 0.000346
Saving checkpoint... 
Iteration: 76063729, states[0] = -31.329673, states[40]= 0.000454
Saving checkpoint... 
Iteration: 91976391, states[0] = -87.780548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108345342, states[0] = 17.090763, states[40]= 0.009749
Saving checkpoint... 
Iteration: 123381611, states[0] = -16.314869, states[40]= 0.001802
Saving checkpoint... 
Iteration: 141239685, states[0] = -53.475574, states[40]= 0.000023
Saving checkpoint... 
Iteration: 160643664, states[0] = -87.804984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181056756, states[0] = -36.311137, states[40]= 0.000258
Saving checkpoint... 
Iteration: 192794124, states[0] = -87.763897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205779249, states[0] = -87.711118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220608019, states[0] = -87.696169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234841221, states[0] = 12.244034, states[40]= 0.007927
Saving checkpoint... 
Iteration: 250624508, states[0] = -87.773456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262304744, states[0] = -87.817747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272530166, states[0] = -11.842790, states[40]= 0.002783
Saving checkpoint... 
Iteration: 286599334, states[0] = -87.684273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301070597, states[0] = -75.180187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319325353, states[0] = 16.512848, states[40]= 0.009341
Saving checkpoint... 
Iteration: 332667865, states[0] = 10.238470, states[40]= 0.007598
Saving checkpoint... 
Iteration: 347186429, states[0] = -7.919636, states[40]= 0.003894
Saving checkpoint... 
Iteration: 362240013, states[0] = -85.858894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374519211, states[0] = -10.806873, states[40]= 0.003060
Saving checkpoint... 
Iteration: 387653390, states[0] = 15.693639, states[40]= 0.008905
Saving checkpoint... 
Iteration: 397258166, states[0] = -87.701785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410604645, states[0] = -87.760040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429689645, states[0] = -23.911832, states[40]= 0.000898
Saving checkpoint... 
Iteration: 450744408, states[0] = -87.636954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466126897, states[0] = 24.706310, states[40]= 0.089592
Saving checkpoint... 
Iteration: 481464748, states[0] = 21.344700, states[40]= 0.026712
Saving checkpoint... 
Iteration: 497413193, states[0] = -87.693257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514988410, states[0] = 6.354687, states[40]= 0.007072
Saving checkpoint... 
Iteration: 533008323, states[0] = -17.770838, states[40]= 0.001563
Saving checkpoint... 
Iteration: 549518514, states[0] = -34.397331, states[40]= 0.000324
Saving checkpoint... 
Iteration: 566281101, states[0] = 28.943692, states[40]= 0.124241
Saving checkpoint... 
Iteration: 582068135, states[0] = -87.672624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600742409, states[0] = -87.722214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621463518, states[0] = 15.596952, states[40]= 0.008861
Saving checkpoint... 
Iteration: 643278228, states[0] = 22.924102, states[40]= 0.055248
Saving checkpoint... 
Iteration: 659475271, states[0] = 5.339609, states[40]= 0.006933
Saving checkpoint... 
Iteration: 674469646, states[0] = 8.422474, states[40]= 0.007346
Saving checkpoint... 
Iteration: 690266878, states[0] = 36.133393, states[40]= 0.104209
Saving checkpoint... 
Iteration: 705679564, states[0] = -48.255132, states[40]= 0.000050
Saving checkpoint... 
Iteration: 721528505, states[0] = -75.102137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735484087, states[0] = -12.146292, states[40]= 0.002705
Saving checkpoint... 
Iteration: 748874107, states[0] = -87.356787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763538599, states[0] = -87.285536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778264680, states[0] = 22.950633, states[40]= 0.055807
Saving checkpoint... 
Iteration: 794887552, states[0] = -87.712820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814238764, states[0] = -87.785516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828276950, states[0] = 15.163919, states[40]= 0.008687
Saving checkpoint... 
Iteration: 848169766, states[0] = -54.615337, states[40]= 0.000019
Saving checkpoint... 
Iteration: 867100240, states[0] = 18.317719, states[40]= 0.011138
Saving checkpoint... 
Iteration: 883661936, states[0] = -48.495882, states[40]= 0.000048
Saving checkpoint... 
Iteration: 904983190, states[0] = -34.704685, states[40]= 0.000313
Saving checkpoint... 
Iteration: 919424857, states[0] = 19.831583, states[40]= 0.015094
Saving checkpoint... 
Iteration: 936627691, states[0] = -8.189689, states[40]= 0.003813
Saving checkpoint... 
Iteration: 955186375, states[0] = -87.314729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974042800, states[0] = -87.739144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990055084, states[0] = -87.787069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008532269, states[0] = -87.709922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024923169, states[0] = 15.596291, states[40]= 0.008862
Saving checkpoint... 
Iteration: 1040886899, states[0] = -87.797861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062113204, states[0] = -5.770525, states[40]= 0.004534
Saving checkpoint... 
Iteration: 1079340467, states[0] = -87.297994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093602342, states[0] = 2.160457, states[40]= 0.006440
Saving checkpoint... 
Iteration: 1107167017, states[0] = -86.486081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126374589, states[0] = -87.786411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143913442, states[0] = 14.370481, states[40]= 0.008422
Saving checkpoint... 
Iteration: 1157417831, states[0] = 10.825550, states[40]= 0.007687
Saving checkpoint... 
Iteration: 1172729903, states[0] = 20.983360, states[40]= 0.022697
Saving checkpoint... 
Iteration: 1187191977, states[0] = -87.753146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207267886, states[0] = -8.966939, states[40]= 0.003584
Saving checkpoint... 
Iteration: 1229124774, states[0] = -44.835527, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1244879350, states[0] = 30.625479, states[40]= 0.125132
Saving checkpoint... 
Iteration: 1259359420, states[0] = -87.780259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275805840, states[0] = -74.118927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294450473, states[0] = -43.303808, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1317085227, states[0] = -2.940431, states[40]= 0.005328
Saving checkpoint... 
Iteration: 1334604629, states[0] = -31.578116, states[40]= 0.000443
Saving checkpoint... 
Iteration: 1353755544, states[0] = -12.083804, states[40]= 0.002721
Saving checkpoint... 
Iteration: 1376760109, states[0] = -21.808773, states[40]= 0.001077
Saving checkpoint... 
Iteration: 1399329461, states[0] = -87.722143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416032549, states[0] = 24.089801, states[40]= 0.078969
Saving checkpoint... 
Iteration: 1435178218, states[0] = -87.789537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457819531, states[0] = -87.704056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479422332, states[0] = -29.987205, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1498568511, states[0] = -4.543708, states[40]= 0.004890
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.698019
 - CaMKt in component CaMK (millimolar): 0.042308
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.005360
 - nass in component intracellular_ions (millimolar): 7.005508
 - ki in component intracellular_ions (millimolar): 144.915301
 - kss in component intracellular_ions (millimolar): 144.915269
 - cansr in component intracellular_ions (millimolar): 1.618521
 - cajsr in component intracellular_ions (millimolar): 1.186923
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007478
 - hf in component INa (dimensionless): 0.691852
 - hs in component INa (dimensionless): 0.691613
 - j in component INa (dimensionless): 0.681005
 - hsp in component INa (dimensionless): 0.446629
 - jp in component INa (dimensionless): 0.654399
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.292548
 - hLp in component INaL (dimensionless): 0.135888
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175594
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.212448
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804133
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966832
 - jca in component ICaL (dimensionless): 0.947949
 - ffp in component ICaL (dimensionless): 0.999863
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009449
 - xrf in component IKr (dimensionless): 0.028758
 - xrs in component IKr (dimensionless): 0.787848
 - xs1 in component IKs (dimensionless): 0.458931
 - xs2 in component IKs (dimensionless): 0.001192
 - xk1 in component IK1 (dimensionless): 0.996812
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:18:25 (48744): called boinc_finish(0)

</stderr_txt>
]]>


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