𝕏

Task 56102682

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_214_1
Workunit 26642973
Created 4 Jul 2024, 20:45:16 UTC
Sent 4 Jul 2024, 23:11:39 UTC
Report deadline 7 Jul 2024, 23:11:39 UTC
Received 5 Jul 2024, 7:33:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241792
Run time 2 hours 26 min 29 sec
CPU time 1 hours 15 min 21 sec
Validate state Valid
Credit 41.96
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.82 MB
Peak swap size 4.00 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_214.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_214_1_r1390207078_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Coppini_2000-conf_214_1_r1390207078_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.147948
     * GNaL_b in INaL: 0.005820
     * Gto_b in Ito: 0.084986
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031789
     * GKs_b in IKs: 0.001929
     * GK1_b in IK1: 0.163273
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.348963
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032263
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10087421, states[0] = 2.302002, states[40]= 0.004288
Saving checkpoint... 
Iteration: 20311469, states[0] = -94.585645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30657653, states[0] = -94.710254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40811168, states[0] = -94.695974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51198523, states[0] = -94.022032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61383487, states[0] = -94.595546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71529320, states[0] = -94.656563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81756169, states[0] = -94.670650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92044810, states[0] = 21.205098, states[40]= 0.002269
Saving checkpoint... 
Iteration: 102150137, states[0] = -45.865120, states[40]= 0.000179
Saving checkpoint... 
Iteration: 112487575, states[0] = -94.636349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122798372, states[0] = -94.663493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133215655, states[0] = -94.225707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143472546, states[0] = -94.628692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153936344, states[0] = -94.659066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163907253, states[0] = -94.659375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174246199, states[0] = -94.335794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184487959, states[0] = -94.632475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194739874, states[0] = -94.660386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204922749, states[0] = -94.658175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215047972, states[0] = 20.337237, states[40]= 0.002482
Saving checkpoint... 
Iteration: 225287094, states[0] = -94.443831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235726819, states[0] = -94.659816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245887628, states[0] = -94.658618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256228214, states[0] = -94.272520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266515187, states[0] = -94.639232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276630886, states[0] = -94.655814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287039547, states[0] = 22.831735, states[40]= 0.002017
Saving checkpoint... 
Iteration: 297078435, states[0] = 8.957243, states[40]= 0.004337
Saving checkpoint... 
Iteration: 307185555, states[0] = -85.928907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317313909, states[0] = -94.493975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327466900, states[0] = -94.624295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337754350, states[0] = -94.659722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347790551, states[0] = -94.659677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358336220, states[0] = -94.526662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368482630, states[0] = -94.629766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378688866, states[0] = -94.658515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388737428, states[0] = -94.659494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398986475, states[0] = -94.655824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408952208, states[0] = -94.656689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419211954, states[0] = -94.204241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429080968, states[0] = 7.788104, states[40]= 0.004427
Saving checkpoint... 
Iteration: 439076354, states[0] = 9.887575, states[40]= 0.004249
Saving checkpoint... 
Iteration: 449046480, states[0] = 20.801164, states[40]= 0.002392
Saving checkpoint... 
Iteration: 459437466, states[0] = -94.611180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469990543, states[0] = -94.655582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480322739, states[0] = -94.507503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490317026, states[0] = -94.498663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501113452, states[0] = -13.668677, states[40]= 0.001852
Saving checkpoint... 
Iteration: 511677878, states[0] = -94.657877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521978555, states[0] = -94.655801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532282649, states[0] = -94.433235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542575440, states[0] = -94.649673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552707911, states[0] = -94.658707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562809986, states[0] = -94.659122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573396535, states[0] = -94.586079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583680849, states[0] = -94.657854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594429658, states[0] = -94.606886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604495670, states[0] = -94.633350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614682736, states[0] = -94.657865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625224030, states[0] = -94.255984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635313293, states[0] = -94.492346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645693537, states[0] = -94.658160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655725467, states[0] = -94.658844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666385242, states[0] = -94.577175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676613143, states[0] = -94.653582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686770779, states[0] = -94.659096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696722420, states[0] = -94.658720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707553192, states[0] = -94.646030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717723224, states[0] = -94.658694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727857816, states[0] = -94.658159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738045667, states[0] = 21.048694, states[40]= 0.002344
Saving checkpoint... 
Iteration: 748293438, states[0] = -94.455848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758385349, states[0] = -94.577091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768956777, states[0] = -94.655903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779336410, states[0] = -94.526117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789708717, states[0] = -94.658285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799846312, states[0] = -94.658215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809913787, states[0] = -94.656868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820162705, states[0] = -57.363144, states[40]= 0.000029
Saving checkpoint... 
Iteration: 830543064, states[0] = -94.644020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840897650, states[0] = -94.657169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851233800, states[0] = -94.291583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861546628, states[0] = -94.644610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871795921, states[0] = -94.658662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882326386, states[0] = -94.512124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892375303, states[0] = -94.568254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902385769, states[0] = -94.577164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912620796, states[0] = -94.653797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923184557, states[0] = -84.456039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933438635, states[0] = -94.610878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944069536, states[0] = 12.751472, states[40]= 0.003895
Saving checkpoint... 
Iteration: 954324558, states[0] = -94.509321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964567444, states[0] = -94.647775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974773994, states[0] = -94.658559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985127210, states[0] = -25.534109, states[40]= 0.001374
Saving checkpoint... 
Iteration: 995139734, states[0] = -36.182851, states[40]= 0.000648
Saving checkpoint... 
Iteration: 1005532567, states[0] = -94.641653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015849091, states[0] = -94.657770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026236764, states[0] = -94.301686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036479653, states[0] = -94.627529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046808657, states[0] = -94.658235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057025750, states[0] = 26.045490, states[40]= 0.001727
Saving checkpoint... 
Iteration: 1067186203, states[0] = -86.821656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077481970, states[0] = -94.628226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087614391, states[0] = -94.652929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097847910, states[0] = -94.657636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108235445, states[0] = -94.296917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118613692, states[0] = -94.652810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128865983, states[0] = -94.657268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139069999, states[0] = 12.565387, states[40]= 0.003922
Saving checkpoint... 
Iteration: 1149142953, states[0] = -38.992676, states[40]= 0.000460
Saving checkpoint... 
Iteration: 1158960938, states[0] = -94.655073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169013804, states[0] = 26.899403, states[40]= 0.014240
Saving checkpoint... 
Iteration: 1179349118, states[0] = -94.541009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189662909, states[0] = -94.655972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200110095, states[0] = -10.758630, states[40]= 0.002371
Saving checkpoint... 
Iteration: 1210300178, states[0] = -94.468128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220545157, states[0] = -94.643678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230695648, states[0] = -94.657135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240607396, states[0] = -94.652005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250865489, states[0] = -94.657050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261252125, states[0] = -94.351409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271473023, states[0] = -94.624785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281591906, states[0] = -94.650324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291694794, states[0] = -94.656997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301882320, states[0] = -94.656632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312017637, states[0] = 26.920664, states[40]= 0.004845
Saving checkpoint... 
Iteration: 1322423784, states[0] = -94.602289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332628971, states[0] = -94.653654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342956645, states[0] = -94.654840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353331462, states[0] = -94.518404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363820529, states[0] = -94.657522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374249395, states[0] = -94.342770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384519966, states[0] = -94.638207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395023937, states[0] = 26.330545, states[40]= 0.001870
Saving checkpoint... 
Iteration: 1405222838, states[0] = -94.249926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415279872, states[0] = -94.425231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425488426, states[0] = -94.629647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435608030, states[0] = -94.651703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445962063, states[0] = -94.654511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456022489, states[0] = 26.525114, states[40]= 0.002098
Saving checkpoint... 
Iteration: 1466383229, states[0] = -94.574027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476826125, states[0] = -94.657245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487034092, states[0] = 24.275276, states[40]= 0.001790
Saving checkpoint... 
Iteration: 1497075403, states[0] = 10.304123, states[40]= 0.004206
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.529354
 - CaMKt in component CaMK (millimolar): 0.004219
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.488203
 - nass in component intracellular_ions (millimolar): 6.488289
 - ki in component intracellular_ions (millimolar): 145.423403
 - kss in component intracellular_ions (millimolar): 145.423388
 - cansr in component intracellular_ions (millimolar): 1.592450
 - cajsr in component intracellular_ions (millimolar): 1.591760
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003757
 - hf in component INa (dimensionless): 0.873385
 - hs in component INa (dimensionless): 0.873386
 - j in component INa (dimensionless): 0.873392
 - hsp in component INa (dimensionless): 0.713516
 - jp in component INa (dimensionless): 0.873395
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719088
 - hLp in component INaL (dimensionless): 0.510951
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891793
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931598
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975474
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002724
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097867
 - xs1 in component IKs (dimensionless): 0.125372
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997433
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:32:39 (214685): called boinc_finish(0)

</stderr_txt>
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