𝕏

Task 56096570

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_908_0
Workunit 26639959
Created 4 Jul 2024, 20:42:08 UTC
Sent 4 Jul 2024, 22:52:43 UTC
Report deadline 7 Jul 2024, 22:52:43 UTC
Received 5 Jul 2024, 20:06:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240530
Run time 2 hours 12 min 27 sec
CPU time 1 hours 48 min 59 sec
Validate state Valid
Credit 41.84
Device peak FLOPS 3.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.03 MB
Peak swap size 32.85 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_908.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_908_0_r1660334022_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_5000-conf_908_0_r1660334022_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.068574
     * GNaL_b in INaL: 0.005854
     * Gto_b in Ito: 0.084614
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031808
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163097
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.156611
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032667
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5744693, states[0] = -94.138594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12224839, states[0] = -94.043574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17417577, states[0] = -93.999185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26098167, states[0] = -93.979538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35708476, states[0] = -93.964918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44602299, states[0] = -93.923035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51046003, states[0] = -93.944819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59111011, states[0] = -93.924099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68772006, states[0] = -93.931617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78860819, states[0] = -93.927676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88334971, states[0] = -93.945273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97964219, states[0] = -93.885320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106340493, states[0] = -93.927142, states[40]= 0.000000
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Iteration: 113033923, states[0] = -93.918028, states[40]= 0.000000
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Iteration: 118141280, states[0] = -93.939525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123093291, states[0] = -93.932742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128634938, states[0] = -93.933944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133590527, states[0] = -93.935586, states[40]= 0.000000
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Iteration: 138442720, states[0] = -93.941138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143002627, states[0] = -93.905508, states[40]= 0.000000
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Iteration: 148031479, states[0] = -93.916816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155107295, states[0] = 0.952391, states[40]= 0.003713
Saving checkpoint... 
Iteration: 160279115, states[0] = -93.549197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165748502, states[0] = -93.944589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170970850, states[0] = -93.939914, states[40]= 0.000000
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Iteration: 176262526, states[0] = -93.929017, states[40]= 0.000000
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Iteration: 182012124, states[0] = -93.911676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188532493, states[0] = -93.937504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195182308, states[0] = -55.195390, states[40]= 0.000110
Saving checkpoint... 
Iteration: 200974331, states[0] = -93.939672, states[40]= 0.000000
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Iteration: 206634765, states[0] = -93.918482, states[40]= 0.000000
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Iteration: 211748463, states[0] = -93.916075, states[40]= 0.000000
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Iteration: 218180457, states[0] = -93.942098, states[40]= 0.000000
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Iteration: 223745793, states[0] = -93.929437, states[40]= 0.000000
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Iteration: 228412875, states[0] = -93.941756, states[40]= 0.000000
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Iteration: 233319706, states[0] = -93.944122, states[40]= 0.000000
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Iteration: 239658701, states[0] = -93.909510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245871756, states[0] = -93.942951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250784244, states[0] = -93.944446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256591279, states[0] = -93.919359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262348598, states[0] = -93.907286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270584579, states[0] = -93.930435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279890452, states[0] = -93.906824, states[40]= 0.000000
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Iteration: 289304153, states[0] = -93.914833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298964429, states[0] = -93.922498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306577236, states[0] = -93.919589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313560568, states[0] = -93.936117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319593888, states[0] = -93.910186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324589088, states[0] = -93.910241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331019228, states[0] = -93.937679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339902351, states[0] = -93.906585, states[40]= 0.000000
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Iteration: 349279239, states[0] = -93.915181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358724809, states[0] = -93.929887, states[40]= 0.000000
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Iteration: 368118054, states[0] = -93.935819, states[40]= 0.000000
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Iteration: 374821688, states[0] = -93.907344, states[40]= 0.000000
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Iteration: 381665896, states[0] = -93.917420, states[40]= 0.000000
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Iteration: 387426707, states[0] = -93.906256, states[40]= 0.000000
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Iteration: 393084335, states[0] = -93.930144, states[40]= 0.000000
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Iteration: 397947773, states[0] = -93.872349, states[40]= 0.000000
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Iteration: 403063339, states[0] = -93.925445, states[40]= 0.000000
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Iteration: 408691511, states[0] = -93.930983, states[40]= 0.000000
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Iteration: 414621152, states[0] = -93.909639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420957167, states[0] = -93.939833, states[40]= 0.000000
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Iteration: 430539536, states[0] = -93.918724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440137343, states[0] = -21.221768, states[40]= 0.002008
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Iteration: 450077226, states[0] = 14.941999, states[40]= 0.001475
Saving checkpoint... 
Iteration: 455432221, states[0] = -93.859521, states[40]= 0.000000
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Iteration: 462053912, states[0] = -93.910459, states[40]= 0.000000
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Iteration: 467227804, states[0] = -93.908215, states[40]= 0.000000
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Iteration: 472387298, states[0] = -93.906477, states[40]= 0.000000
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Iteration: 476911754, states[0] = -93.912591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482852203, states[0] = -93.753482, states[40]= 0.000000
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Iteration: 488794334, states[0] = -93.927259, states[40]= 0.000000
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Iteration: 494348417, states[0] = -93.913634, states[40]= 0.000000
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Iteration: 501163970, states[0] = -93.931815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507493738, states[0] = -93.905400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512838968, states[0] = -93.726427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518631820, states[0] = -93.932986, states[40]= 0.000000
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Iteration: 524127849, states[0] = -93.917986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533517252, states[0] = -93.937363, states[40]= 0.000000
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Iteration: 543188069, states[0] = -93.941878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552344702, states[0] = -93.906757, states[40]= 0.000000
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Iteration: 561563809, states[0] = -93.919419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570433547, states[0] = -93.860457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576693696, states[0] = -93.916450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584379456, states[0] = -93.912923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593798829, states[0] = -93.926908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603277137, states[0] = -93.943775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612020677, states[0] = -93.910645, states[40]= 0.000000
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Iteration: 618369922, states[0] = -93.942269, states[40]= 0.000000
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Iteration: 623833612, states[0] = -93.925727, states[40]= 0.000000
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Iteration: 628977205, states[0] = -93.921511, states[40]= 0.000000
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Iteration: 634003185, states[0] = -93.920811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639591353, states[0] = -93.909600, states[40]= 0.000000
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Iteration: 645641250, states[0] = -93.938071, states[40]= 0.000000
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Iteration: 651826477, states[0] = -93.913720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659204929, states[0] = -93.916056, states[40]= 0.000000
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Iteration: 668635031, states[0] = -93.932575, states[40]= 0.000000
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Iteration: 677812830, states[0] = -93.661055, states[40]= 0.000000
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Iteration: 687125137, states[0] = -93.909059, states[40]= 0.000000
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Iteration: 697117206, states[0] = -93.909144, states[40]= 0.000000
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Iteration: 706458632, states[0] = -93.921867, states[40]= 0.000000
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Iteration: 716431688, states[0] = -93.922602, states[40]= 0.000000
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Iteration: 725968878, states[0] = -93.938817, states[40]= 0.000000
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Iteration: 735505336, states[0] = -93.905354, states[40]= 0.000000
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Iteration: 744578462, states[0] = -93.909572, states[40]= 0.000000
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Iteration: 753921537, states[0] = -93.922820, states[40]= 0.000000
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Iteration: 760403375, states[0] = -93.829727, states[40]= 0.000000
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Iteration: 766133388, states[0] = -93.932449, states[40]= 0.000000
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Iteration: 771341106, states[0] = -93.925206, states[40]= 0.000000
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Iteration: 775958775, states[0] = -93.939090, states[40]= 0.000000
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Iteration: 781631933, states[0] = -93.917397, states[40]= 0.000000
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Iteration: 786818820, states[0] = -93.913598, states[40]= 0.000000
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Iteration: 794254129, states[0] = -93.914804, states[40]= 0.000000
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Iteration: 803554109, states[0] = -93.935420, states[40]= 0.000000
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Iteration: 813099464, states[0] = -93.932118, states[40]= 0.000000
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Iteration: 822136986, states[0] = -93.908645, states[40]= 0.000000
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Iteration: 831532560, states[0] = -93.919673, states[40]= 0.000000
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Iteration: 840899703, states[0] = -93.940974, states[40]= 0.000000
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Iteration: 850232274, states[0] = -93.273037, states[40]= 0.000000
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Iteration: 859631663, states[0] = -93.908641, states[40]= 0.000000
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Iteration: 868307322, states[0] = -93.943053, states[40]= 0.000000
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Iteration: 877859672, states[0] = -93.766453, states[40]= 0.000000
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Iteration: 886975390, states[0] = -93.910790, states[40]= 0.000000
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Iteration: 896088462, states[0] = -93.933914, states[40]= 0.000000
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Iteration: 902756638, states[0] = -93.450969, states[40]= 0.000000
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Iteration: 911733701, states[0] = -93.914982, states[40]= 0.000000
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Iteration: 920979807, states[0] = -93.938036, states[40]= 0.000000
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Iteration: 929989390, states[0] = -93.904622, states[40]= 0.000000
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Iteration: 935969205, states[0] = -93.938400, states[40]= 0.000000
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Iteration: 941043967, states[0] = -93.935547, states[40]= 0.000000
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Iteration: 947514773, states[0] = 31.586692, states[40]= 0.011286
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Iteration: 952249899, states[0] = -93.907020, states[40]= 0.000000
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Iteration: 957884705, states[0] = -93.805643, states[40]= 0.000000
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Iteration: 963265382, states[0] = -93.943068, states[40]= 0.000000
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Iteration: 968736504, states[0] = -93.928298, states[40]= 0.000000
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Iteration: 974107126, states[0] = -93.917592, states[40]= 0.000000
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Iteration: 979577898, states[0] = -93.909125, states[40]= 0.000000
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Iteration: 985456507, states[0] = -93.877573, states[40]= 0.000000
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Iteration: 990456245, states[0] = -93.877380, states[40]= 0.000000
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Iteration: 997401517, states[0] = -93.905321, states[40]= 0.000000
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Iteration: 1006645341, states[0] = -93.916662, states[40]= 0.000000
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Iteration: 1016041057, states[0] = -93.935515, states[40]= 0.000000
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Iteration: 1025307401, states[0] = -93.644592, states[40]= 0.000000
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Iteration: 1033589653, states[0] = -93.933603, states[40]= 0.000000
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Iteration: 1043185353, states[0] = -93.940766, states[40]= 0.000000
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Iteration: 1052655901, states[0] = -34.862818, states[40]= 0.001629
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Iteration: 1061979688, states[0] = -93.910386, states[40]= 0.000000
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Iteration: 1067773982, states[0] = -93.526694, states[40]= 0.000000
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Iteration: 1073632321, states[0] = -93.931896, states[40]= 0.000000
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Iteration: 1079164235, states[0] = -93.916107, states[40]= 0.000000
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Iteration: 1084775990, states[0] = -93.906469, states[40]= 0.000000
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Iteration: 1090312502, states[0] = -93.659317, states[40]= 0.000000
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Iteration: 1097641995, states[0] = -24.681745, states[40]= 0.002442
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Iteration: 1103696838, states[0] = -93.929448, states[40]= 0.000000
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Iteration: 1108363686, states[0] = -93.941488, states[40]= 0.000000
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Iteration: 1114646745, states[0] = -93.907954, states[40]= 0.000000
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Iteration: 1120192735, states[0] = -63.670966, states[40]= 0.000027
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Iteration: 1130097571, states[0] = 6.067497, states[40]= 0.003132
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Iteration: 1139465873, states[0] = -93.910448, states[40]= 0.000000
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Iteration: 1148231027, states[0] = -93.942289, states[40]= 0.000000
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Iteration: 1154330580, states[0] = -93.912675, states[40]= 0.000000
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Iteration: 1160023402, states[0] = 31.451708, states[40]= 0.000639
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Iteration: 1164691157, states[0] = -93.907303, states[40]= 0.000000
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Iteration: 1173520319, states[0] = -93.936011, states[40]= 0.000000
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Iteration: 1182982447, states[0] = -93.893258, states[40]= 0.000000
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Iteration: 1191995980, states[0] = -93.909888, states[40]= 0.000000
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Iteration: 1204619747, states[0] = -93.908129, states[40]= 0.000000
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Iteration: 1210825876, states[0] = -93.942117, states[40]= 0.000000
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Iteration: 1219613786, states[0] = -93.908178, states[40]= 0.000000
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Iteration: 1228604719, states[0] = -93.932648, states[40]= 0.000000
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Iteration: 1237887085, states[0] = -93.808364, states[40]= 0.000000
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Iteration: 1244353348, states[0] = -93.912097, states[40]= 0.000000
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Iteration: 1250015907, states[0] = 31.688206, states[40]= 0.007628
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Iteration: 1255820151, states[0] = -93.942126, states[40]= 0.000000
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Iteration: 1261172357, states[0] = -93.930038, states[40]= 0.000000
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Iteration: 1265802067, states[0] = -93.942346, states[40]= 0.000000
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Iteration: 1271963049, states[0] = -93.910235, states[40]= 0.000000
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Iteration: 1277318317, states[0] = -93.905634, states[40]= 0.000000
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Iteration: 1282848341, states[0] = -93.744408, states[40]= 0.000000
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Iteration: 1289115706, states[0] = -93.916785, states[40]= 0.000000
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Iteration: 1294158473, states[0] = -93.915817, states[40]= 0.000000
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Iteration: 1299759813, states[0] = -93.906235, states[40]= 0.000000
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Iteration: 1304763035, states[0] = -93.906189, states[40]= 0.000000
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Iteration: 1309313946, states[0] = -93.912676, states[40]= 0.000000
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Iteration: 1317052122, states[0] = -93.908831, states[40]= 0.000000
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Iteration: 1326343064, states[0] = -93.924072, states[40]= 0.000000
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Iteration: 1335560518, states[0] = -93.922937, states[40]= 0.000000
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Iteration: 1343579828, states[0] = -93.933384, states[40]= 0.000000
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Iteration: 1349077148, states[0] = -93.917574, states[40]= 0.000000
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Iteration: 1354089664, states[0] = -93.917266, states[40]= 0.000000
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Iteration: 1358794449, states[0] = -93.925575, states[40]= 0.000000
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Iteration: 1362449367, states[0] = -93.904154, states[40]= 0.000000
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Iteration: 1372380622, states[0] = -93.904803, states[40]= 0.000000
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Iteration: 1382060019, states[0] = -93.908594, states[40]= 0.000000
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Iteration: 1389850398, states[0] = -93.905078, states[40]= 0.000000
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Iteration: 1395704832, states[0] = -93.941014, states[40]= 0.000000
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Iteration: 1401837705, states[0] = -93.912069, states[40]= 0.000000
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Iteration: 1407136068, states[0] = -93.907525, states[40]= 0.000000
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Iteration: 1412647476, states[0] = -28.678950, states[40]= 0.002478
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Iteration: 1420578824, states[0] = -93.927032, states[40]= 0.000000
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Iteration: 1429882305, states[0] = -93.904675, states[40]= 0.000000
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Iteration: 1439263774, states[0] = -93.913370, states[40]= 0.000000
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Iteration: 1448082254, states[0] = -93.927690, states[40]= 0.000000
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Iteration: 1457174245, states[0] = -93.906946, states[40]= 0.000000
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Iteration: 1466789041, states[0] = -93.912834, states[40]= 0.000000
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Iteration: 1476612336, states[0] = -93.916500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486292969, states[0] = -93.925378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495414347, states[0] = -93.840368, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.779399
 - CaMKt in component CaMK (millimolar): 0.001583
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.713687
 - nass in component intracellular_ions (millimolar): 6.713811
 - ki in component intracellular_ions (millimolar): 145.148009
 - kss in component intracellular_ions (millimolar): 145.148000
 - cansr in component intracellular_ions (millimolar): 1.834170
 - cajsr in component intracellular_ions (millimolar): 1.834032
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004053
 - hf in component INa (dimensionless): 0.859119
 - hs in component INa (dimensionless): 0.859119
 - j in component INa (dimensionless): 0.859121
 - hsp in component INa (dimensionless): 0.687674
 - jp in component INa (dimensionless): 0.859123
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698592
 - hLp in component INaL (dimensionless): 0.503116
 - a in component Ito (dimensionless): 0.000672
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.997552
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999151
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998692
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005418
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002195
 - xs1 in component IKs (dimensionless): 0.024557
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:54:01 (37949): called boinc_finish(0)

</stderr_txt>
]]>